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Claire Durrant

@clairedurrant1.bsky.social
935 followers 1.1K following 45 posts

Group leader using human brain slice models to study Alzheimer’s disease at the University of Edinburgh. Race Against Dementia Dyson Fellow & Emerging Leader at the UK Dementia Research Institute. Mum, wife, nature lover. (Photo:Chris Watt)

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Reposted by Claire Durrant
Dervis Salih @dervissalih1.bsky.social · 16/06/2025
We are happy to seek 3 post-docs across Edinburgh Napier, Glasgow & UCL in an exciting project to investigate mechanisms linking glial ageing/longevity & neurodegeneration (MRC-funded). Info attached @nathanwoodling.bsky.social @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social
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Anna Mallach @annamallach.bsky.social · 13/06/2025
Last chance to apply to join my team at the UKDRI at Imperial investigating the interaction of glia cells in neurodegeneration, funded by ARUK! @ukdri.ac.uk @alzheimersresearchuk.org
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Danilo Negro @danineuro.bsky.social · 25/05/2025
Had a brilliant time speaking at @pintofscience.uk with my talk “Gold, Guns and Brain Cells” — exploring neurodegeneration and resilience in Alzheimer’s disease. Huge thanks to everyone who came, asked thoughtful questions, and made it such a fun night! 🧠🍻 #pint25
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Rafeeque Mavoor @rafeequemavoor.bsky.social · 13/05/2025
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!
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British Neuroscience Association @britishneuro.bsky.social · 13/05/2025
🗓️ Tuesday 20th May | 🕓 16:00 - 17:00 (BST) | 💻 Online & Free Are you interested in running your own lab? This webinar is perfect for those in electrophysiology or related fields Register now and take the next step in your research journey 🥼 www.bna.org.uk/mediacentre/...
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Claire Durrant @clairedurrant1.bsky.social · 13/05/2025
Very excited to join, and help grow, this wonderful society journal! In particular, would love to encourage submissions from masters or mini PhD projects to publish as short reports. There are so many small, rigorous, studies that often remain unpublished. This work is valuable to the community!
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Dr Soraya M @sorayam.bsky.social · 12/05/2025
Really privileged to be spending the week at the University of Eastern Finland, giving a talk as part of their course on electrophysiological techniques for human neuron function and also enjoying the wonderful location and weather.
A photo of a lectern that says university of eastern Finland and behind it is a slide that says electrophysiological techniques to measure and interpret human neuron function A picture of very blue sky some water and trees. A very pretty sparse landscapeA picture of soraya by the water with very clear blud skies
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Claire Durrant @clairedurrant1.bsky.social · 07/05/2025
Amazing work by the Booker lab here in Edinburgh! Another demonstration of the power of live human brain tissue 🧠.
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Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 30/04/2025
I have absolutely loved my time as President of @britishneuro.bsky.social . And what an epic end giving a speech in the gorgeous Liverpool cathedral under an installation art piece of the sun. Thank you to CEO and buddy Laura Ajram and excellent exec team.
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UK Dementia Research Institute @ukdri.ac.uk · 30/04/2025
Researchers led by @clairedurrant1.bsky.social have used living human brain tissue to show for the first time how a toxic protein in Alzheimer’s can damage synapses👏 The team hope the cutting-edge tool could help accelerate the development of new treatments👉 buff.ly/cXK2LIa
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Claire Durrant @clairedurrant1.bsky.social · 30/04/2025
Fantastic coverage from @theguardian.com on our latest work!
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Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 30/04/2025
Fantastic to see this work from @clairedurrant1.bsky.social group out in print! Important results using living human brain tissue to study Alzheimer’s disease www.nature.com/articles/s41...
nature.com
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures - Nature Communications
Understanding synapse loss in Alzheimer’s disease has been hampered by a lack of human model systems. Here, the authors show that manipulation of physiological or pathological Aβ has differing effects...
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Claire Durrant @clairedurrant1.bsky.social · 30/04/2025
Fantastic coverage of our recent work using living human brain slices to study Alzheimer’s disease from @itvnews.bsky.social www.itv.com/news/2025-04...
itv.com
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Claire Durrant @clairedurrant1.bsky.social · 30/04/2025
So excited to see our work finally out today in Nature Communications! Brilliant summary by co-first author @sorayam.bsky.social below!
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British Neuroscience Association @britishneuro.bsky.social · 24/04/2025
🧠 Can we defeat dementia? This week, BNA President @tspiresjones.bsky.social took the TEDx stage to explore the powerful neuroscience that could help us do just that. 🎥 Watch her talk here: youtu.be/hJMEAd9ODis #TEDx #Neuroscience #Dementia #BNA
youtu.be
The neuroscience of defeating dementia | Prof Tara Spires-Jones | TEDxUniversityofStAndrews
YouTube video by TEDx Talks
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Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 23/04/2025
It was a pleasure to visit St Andrews to deliver a TEDx talk! www.youtube.com/watch?v=hJME...
youtube.com
The Neuroscience of Defeating Dementia | Prof Tara Spires-Jones | TEDxUniversityofStAndrews
YouTube video by TEDx Talks
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Claire Durrant @clairedurrant1.bsky.social · 21/04/2025
Such an honor to conduct Andrew’s viva. Was a great discussion and wonderful to hear all about his hard work! A credit to @kunathlab.bsky.social! One of the nicest post- viva receptions I’ve seen (I want to start a campaign that every institution have a tannoy announcement for new doctors!)
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Sam Halpert @samhalpert.bsky.social · 15/04/2025
Even accepting the premise that AI produces useful writing (which no one should), using AI in education is like using a forklift at the gym. The weights do not actually need to be moved from place to place. That is not the work. The work is what happens within you.
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Dr Soraya M @sorayam.bsky.social · 10/04/2025
We have proofs!!!!
A photo showing a manuscript with received 27 feb 2025. Accepted 1 April 2025 (not an April fools). Published online xx xx 2025
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Danilo Negro @danineuro.bsky.social · 14/04/2025
Curious about how the brain might adapt to neurodegeneration? Come hear me talk about gold, guns and brain cells at @pintofscience.uk in Edinburgh! 🧠🍻 #pint25
pintofscience.co.uk
The Resilient Mind: Fighting Against Dementia
Join us for an insightful event exploring the fascinating world of the brain. The first talk dives into the science of neurodegeneration, where brain cells…
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James Catterson @scotsfriction.bsky.social · 01/04/2025
I also had a chance to speak with HRH The Duchess of Edinburgh about our work using flies in dementia research. Everybody loves the flies. 😇😅🥰
Me chatting to HRH The Duchess of Edinburgh about the cool stuff we do with Drosophila
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Claire Durrant @clairedurrant1.bsky.social · 01/04/2025
Amazing to welcome HRH The Duchess of Edinburgh, Patron of Race Against Dementia to our lab! An incredible opportunity to showcase our work with living human brain slice cultures and the importance of investing in dementia research. We are very lucky to have her support.
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Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 10/03/2025
One of the great joys of working for the University of Edinburgh @edinburgh-uni.bsky.social is the gorgeous Firbush retreat in the highlands where we take our neuroscience students in their final year.
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Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 10/03/2025
Delighted to share our new preprint where we observe synapse ingestion by glia around plaques in aged cats with cognitive dysfunction syndrome. A fab collab with Edinburgh Veterinary colleages and Dr McGeachan's first corresponding author paper! www.biorxiv.org/content/10.1...
biorxiv.org
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Brain Communications @braincomms.bsky.social · 07/03/2025
Amazing talk from our editor-in-chief @tspiresjones.bsky.social about Synapse-glia interaction in the pathogenesis of Alzheimer’s disease #BrainConf25 👏🏻👏🏻👏🏻
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Brain Communications @braincomms.bsky.social · 07/03/2025
Brain Comms people at #BrainConf25 😁 @tspiresjones.bsky.social and @manuelamarescotti.bsky.social
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Rosie Jackson @aramblingrosie.bsky.social · 05/03/2025
Now is the moment!! If you'd like to come and do a PhD with me in sunny Dundee then I have not 1 but 2 funded PhD positions in my lab looking at #ApoE. Please reach out with any questions! Come do science with us, it'll be fun! www.dundee.ac.uk/phds/opportu... www.dundee.ac.uk/phds/opportu...
dundee.ac.uk
Investigating the impact of ApoE source and isoform on Neuroinflammation | University of Dundee, UK
A PhD project at the University of Dundee
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Claire Durrant @clairedurrant1.bsky.social · 04/03/2025
With so much horrible news at the moment- amazing to celebrate the legacy of someone wonderful and selfless! Having needed Anti-D injections myself it’s incredible to think my two boys were born happy and healthy because of science and amazing people like him.
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Dr Soraya M @sorayam.bsky.social · 03/03/2025
My favourite time of the year is when we get visitors from Alzheimers Scotland. It’s great to be able to share some of the cool research we do and hear what they think, and they share their inspirational stories with us and how they advocate for those living with dementia. 💜
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Edinburgh Neuroscience @edinunineuro.bsky.social · 03/03/2025
Guests from Alzheimer Scotland recently visited our labs, sharing their inspiring personal stories, the impact of diagnoses on their lives as well as the advocacy work they do for those living with dementia and their families. A reminder of why we do what we do. 🧠🔬🧫https://tinyurl.com/97z8ha9v
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Claire Durrant @clairedurrant1.bsky.social · 26/02/2025
Fighting the urge to start every email response with ‘sorry’ this week 🤦🏻‍♀️. A tsunami of post-mat leave requests/ to do lists colliding with a poorly baby is a fun balancing act!
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Claire Durrant @clairedurrant1.bsky.social · 25/02/2025
Aaaannd the baby has RSV and bronchiolitis! (Gutted to have missed out on the new RSV jab when pregnant by a few weeks!)Trip to A&E for suction and now back to the extreme sport of juggling running a lab whilst caring for a sick child 🫠 counting down the seconds until spring!
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Claire Durrant @clairedurrant1.bsky.social · 21/02/2025
2 weeks back of work after 6 months of maternity leave. In learning to rebalance life with a baby, toddler and a full time job I have the following early observations (thread!). Solidarity to all academic parents out there!
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Katie Langin @klangin.bsky.social · 14/02/2025
Dear federal scientists: If you have been affected by the probationary firings and would be willing to speak with Science, please reach out to me by email (klangin@aaas.org) or on Signal. We can guarantee annonymity.
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Ariel K. Frame @arielframe.bsky.social · 10/12/2024
Fascinating correlation here doi.org/10.1093/brai... If this leaves you wondering what good high CSF amyloid beta might do, check out one of my favourite reviews doi.org/10.1007/s004... by @tspiresjones.bsky.social @clairedurrant1.bsky.social
doi.org
Increases in amyloid-β42 slow cognitive and clinical decline in Alzheimer’s disease trials
By analysing data from over 25 000 patients with Alzheimer’s disease in 24 randomized controlled trials, Abanto et al. show that the cognitive improvements
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Itai Yanai @itaiyanai.bsky.social · 10/12/2024
You have to believe you can write a manuscript in a week, so that it will end up only taking three months.
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James Catterson @scotsfriction.bsky.social · 05/12/2024
Putting these guys to bed now for Xmas/New Year 😴 🥶 🎄 See you in 2025, wee flies! 🪰 #Drosophila
Hundreds of Drosophila stocks in a cold incubator A different cold incubator with hundreds of Drosophila stocks
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Neil Renic @ncrenic.bsky.social · 04/12/2024
Two stages of writing: 1) This shouldn't take too long 2) Oh no
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Claire Durrant @clairedurrant1.bsky.social · 27/11/2024
Productive day of maternity leave! Paper revisions sent back to a journal and my little one rolled over for the first time! I’ll pretend it’s always like this 😅😅 #academicparent #delusional
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Dr Soraya M @sorayam.bsky.social · 25/11/2024
Caught one! #ephys #neuroscience
A ephys trace of a neuron showing rebound firing after a negative current injection from a brain slice.
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Rosie Jackson @aramblingrosie.bsky.social · 20/11/2024
One week left to apply for this job!! I'm looking for a research tech to come and work on Alzheimers and ApoE! If you love cell culture, astrocytes, APOE or just fun science with fun people then come do science with us in beautiful Dundee! tinyurl.com/a33kjn49 Seriously the sunsets are on point!
Sunset over the tay bridge from The school of life sciences building in dundee
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Cathy Abbott @cathyabbott.bsky.social · 21/11/2024
The BNA scholars programme is now open for applications - this is a great scheme, instigated by @landreae.bsky.social (I can't tag the BNA as they aren't here yet I don't think) www.bna.org.uk/mediacentre/...
bna.org.uk
Applications welcome for 2025 entry to the BNA Scholars Programme | Media | The British Neuroscience Association
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adam grieve @adamgrieve.bsky.social · 15/11/2024
Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c
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James Catterson @scotsfriction.bsky.social · 15/11/2024
🧠Re-sharing this as the list is growing. 🌲 Let me know if I've left you out - or if you think I should add someone! 🧠 go.bsky.app/S6FfsTp
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Dr Soraya M @sorayam.bsky.social · 10/11/2024
I find intros so cringe aha, but here we go. Big electrophysiology fan, working in human brain slice models at the minute to model dementia, ex in vivo patcher and other forms of ephys. Currently employed as a post doc with Dr Claire Durrant at the University of Edinburgh.
A screen showing action potentials from a single cell recording in a sliceMe at the rig talking to students about electrophysiology An in vivo patch recording from the hippocampus showing bursting action potentialsA 2 photon image of a neuron being recorded in vivo
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