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Pedro Papotto

@ph-papotto.bsky.social
335 followers 204 following 29 posts

Dean's Prize Fellow @ The University of Manchester Currently using worms to uncover the secrets of rare immune cell populations 🇧🇷🇬🇧

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Reposted by Pedro Papotto
Waggoner Lab @labwaggoner.bsky.social · 13h
Lung anthelmintic responses during hookworm infection are regulated by skin-derived γδ T cells www.science.org/doi/10.1126/... @sciimmunology.bsky.social @ph-papotto.bsky.social @profjudiallen.bsky.social
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Salva Iborra @salva-iborra.bsky.social · 30/12/2025
On the use of murine models: Results should be interpreted with caution. Batf3-deficient mice have been traditionally used as a model to study the function of cDC1; however, this transcription factor seems to play other essential roles in other immune populations👇
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Pedro Papotto @ph-papotto.bsky.social · 19/12/2025
Isn't this the coolest Christmas present (or miracle) for a #gdTcell aficionado?! Our latest preprint showing the role of BATF3 on gd T cells is ou on bioRxiv: www.biorxiv.org/content/10.6...
biorxiv.org
BATF3 controls the homeostatic maintenance and function of innate-like γδ T cells
γδ T cells compose an evolutionarily conserved lineage of lymphocytes, with both adaptive- and innate-like characteristics, contributing to tissue homeostasis, immune surveillance, and rapid responses...
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Reposted by Pedro Papotto
bioRxiv Immunology @biorxiv-immuno.bsky.social · 18/12/2025
BATF3 controls the homeostatic maintenance and function of innate-like γδ T cells www.biorxiv.org/content/10.64898/20…
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Salva Iborra @salva-iborra.bsky.social · 25/11/2025
Excited to share our new paper in @jem.org! 🎉 We reveal a key mechanism showing how tissue-resident memory CD8⁺ T cells (#Trm) amplify antiviral protection during reinfection. #immuno 🧵👇1/6
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Megan Priestley @megtriesscience.bsky.social · 04/11/2025
My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...
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Joana F Neves @nevesjf.bsky.social · 21/10/2025
We are recruiting!!! Postdoc position available in my lab to develop this exciting project with @alexfsantos2401.bsky.social advance our understanding of food allergy and oral tolerance in early life. #ILC #organoids #FoodAllergy www.kcl.ac.uk/jobs/128585-...
kcl.ac.uk
Research Associate | King's College London
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Reposted by Pedro Papotto
Becky Dodd @becky-dodd.bsky.social · 15/10/2025
📣 PhD project available 📣 Interested in immuno-matrix interactions and matrix regulation? This project will investigate how hyaluronan is cleared from the lungs after infection. 🫁 @profjudiallen.bsky.social @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social www.findaphd.com/phds/project...
findaphd.com
(MCR DTP) Macrophage clearance of hyaluronan: mechanisms and consequences for lung disease at The University of Manchester on FindAPhD.com
PhD Project - (MCR DTP) Macrophage clearance of hyaluronan: mechanisms and consequences for lung disease at The University of Manchester, listed on FindAPhD.com
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Reposted by Pedro Papotto
Joana F Neves @nevesjf.bsky.social · 07/10/2025
PhD opportunity to study intestinal immune cells using our pioneer human organoid models at the Joana F Neves and Robin Dart labs @kingscollegelondon.bsky.social through #MRC Doutoral training program kcl-mrcdtp.com/project/deco... Applications opening soon! #gdTcells #IBD #gut #organoids
kcl-mrcdtp.com
Decoding γδ T cell-epithelial interactions in the human intestine in health and disease - MRC DTP
The human gut epithelium performs vital absorptive functions, while simultaneously forming a physical barrier between the gut contents and the body. As such it is essential for health and its dysregul...
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Pedro Papotto @ph-papotto.bsky.social · 04/08/2025
Needing some help from all the mouse doctors around! Does anyone know who might keep a B10.D2 mouse colony in the UK (or even mainland Europe)?
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Reposted by Pedro Papotto
Judi Allen @profjudiallen.bsky.social · 16/07/2025
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...
ukri.org
Centre to study how exposome causes chronic inflammatory disease
A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
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Reposted by Pedro Papotto
Lydia Becker Institute @lydiabeckeriii.bsky.social · 16/07/2025
🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases. #Exposome #ImmunoSky sites.manchester.ac.uk/lydia-becker...
sites.manchester.ac.uk
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A groundbreaking £50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.
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Reposted by Pedro Papotto
Worboys Lab @worboyslab.bsky.social · 14/07/2025
Delighted to advertise a collaborative postdoc position available in the lab to develop new proximity labelling tools, funded by a BBSRC Transformative Research Technology grant: www.jobs.manchester.ac.uk/Job/JobDetai... #ChemicalBiology #SyntheticChemistry
jobs.manchester.ac.uk
Research Associate in Synthetic Chemistry and Chemical Biology:Oxford Road
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Reposted by Pedro Papotto
Bertuzzi Lab @bertuzzilab.bsky.social · 04/07/2025
Interested in working on Mucorales adaptation? Thanks to new funding from @wellcometrust.bsky.social, we will have two postdoc and a technician positions advertised very soon! if interested, please get in touch for more information.
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Reposted by Pedro Papotto
Thiago Carvalho @cyrilpedia.bsky.social · 01/07/2025
ICYMI: Junior PI positions in Kyoto at @ccii-kyoto.bsky.social, a new center led by Tasuku Honjo (DIrector) & Sidonia Fagarasan (Vice Director) #Immunology #Immunotherapy #ScienceJobs
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Reposted by Pedro Papotto
Marc Veldhoen @marcveld.bsky.social · 03/06/2025
🚨Great new MSc and PhD positions available @gimmfoundation! Check out the links or use the QR code. MSc: www.medicina.ulisboa... PhD: gimm.pt/course/phd-p...
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Reposted by Pedro Papotto
Worboys Lab @worboyslab.bsky.social · 29/05/2025
The deadline for this PhD is fast approaching. We are looking for a promising synthetic chemist to make new chemical biology tools to learn more about nucleic acid interactions. This is a collaborative project with the Trowbridge Lab in @uomscieng.bsky.social. If interested, get in touch soon!
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Reposted by Pedro Papotto
Worboys Lab @worboyslab.bsky.social · 14/05/2025
Our latest research is now available as a pre-print at BioRxiv. We show that the immune checkpoint receptor TIGIT cannot signal in T cells without simultaneous TCR stimulation. #ImmunoSky www.biorxiv.org/content/10.1...
biorxiv.org
Inhibitory TIGIT signalling is dependent on T cell receptor activation
TIGIT is an immune checkpoint receptor that can signal via cytoplasmic ITT-like and ITIM motifs to regulate T cell function. The signalling molecules that mediate inhibitory TIGIT signalling in T cell...
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Matthew Sinton 🏳️‍🌈 @mcsinton.bsky.social · 08/05/2025
Hi everyone 👋 I’ve been nominated for the role of ECR representative position on the Member Representative Forum at @britsocimm.bsky.social. If you’d like to see me in this position and want to vote for me, you can follow this link: www.immunology.org/news/bsi-com... #immunosky
immunology.org
BSI committee elections 2025 | British Society for Immunology
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Reposted by Pedro Papotto
Worboys Lab @worboyslab.bsky.social · 16/05/2025
We have a PhD available in the lab to design new chemical tools to do super resolution proximity labelling of nucleotides. Come join us!! #ChemSky #ChemBio www.findaphd.com/phds/project...
findaphd.com
(EPSRC DTP) Super-resolution proximity nucleotide labelling at The University of Manchester on FindAPhD.com
PhD Project - (EPSRC DTP) Super-resolution proximity nucleotide labelling at The University of Manchester, listed on FindAPhD.com
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Reposted by Pedro Papotto
Doug Dyer @douglaspdyer.bsky.social · 28/04/2025
So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...
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Payal Yokota @payalyokota.bsky.social · 25/04/2025
Excited to share our latest study @cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social for his outstanding mentorship throughout! Pls read/share!👇 www.cell.com/immunity/ful...
cell.com
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
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γδ T cell Forum @forum-gd.bsky.social · 17/04/2025
Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer. #gdTcells
nature.com
Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer - Nature Cancer
Silva-Santos and colleagues provide in vivo preclinical evidence supporting a therapeutic use of Delta One T cells to tackle colorectal cancer and propose activating natural killer cell receptor NKG2D...
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Reposted by Pedro Papotto
D’Agostino Lab @dagostinolab.bsky.social · 07/04/2025
Our latest study @science.org #Immunology on perception of #hunger and #immunity. #BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones. @ukri.org @fbmh-uom.bsky.social www.science.org/doi/10.1126/...
science.org
Brain sensing of metabolic state regulates circulating monocytes
Brain-initiated hunger signals control circulating monocyte dynamics.
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Reposted by Pedro Papotto
The University of Manchester @manchester.ac.uk · 07/04/2025
What really happens to your immune system when you fast? New research from @fbmh-uom.bsky.social could be a game-changer for how we think about immunity, nutrition, and inflammation. Let’s break it down. #scicomms
media.tenor.com
a close up of a woman 's face with a surprised look on her face .
Alt: a close up of a woman 's face with a surprised look on her face .
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Hepworth Lab @hepworth-lab.bsky.social · 05/04/2025
www.manchester.ac.uk/about/news/s...
manchester.ac.uk
Scientists cast new light on how fasting impacts the immune system
New research from The University of Manchester may reshape our understanding of what happens to the immune system when we fast.Funded by the Biotechnology and Biological Sciences Research Council (BBS...
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Pedro Papotto @ph-papotto.bsky.social · 08/04/2025
Really thrilled to have been awarded an @acmedsci.bsky.social Springboard Award! This new PI thing is definitely starting to feel real now! The #Springboard25 will help me to kickstart some cool work on innate-like T cells in skin and lungs at the @lydiabeckeriii.bsky.social! Exciting times ahead!
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Academy of Medical Sciences @acmedsci.bsky.social · 07/04/2025
📢 We're making our largest ever investment in early-career researchers Through #Springboard25, we’re investing £7.6m in 62 researchers to drive innovations that improve health and wellbeing 🔬 Congrats to all 2025 awardees! 🎉 👉 bit.ly/springboard2... @thebhf.bsky.social @wellcometrust.bsky.social
Three people wearing lab coats and talking to each other while writing on a whiteboard
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Reposted by Pedro Papotto
Worboys Lab @worboyslab.bsky.social · 26/03/2025
Our lab has a postdoc position available to use super-resolution microscopy to understand how nanoscopic localisation of immune checkpoints dictates their function. Please get in touch if interested in applying. www.jobs.manchester.ac.uk/Job/JobDetai... #ImmunoSky #Imaging #Microscopy
jobs.manchester.ac.uk
Research Associate in Imaging Human Immunology:Oxford Road
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The Minutti Lab @minuttilab.bsky.social · 08/03/2025
🔬 Looking for OP9 cells overexpressing Notch ligands (Jagged1, Jagged2, Delta1, Delta3, Delta4). We already have Jagged1, Delta1, and Delta4 but need the full set—happy to cover shipping & set up an MTA! Any leads? 🧫 #immunology #Notch
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Joana F Neves @nevesjf.bsky.social · 03/03/2025
Looking for an excellent & highly motivated postdoctoral researcher to join our team to develop an exciting project focused on the generation of beneficial Innate Lymphoid Cells #ILC for the treatment of Inflammatory Bowel Disease #IBD using #organoids. Please share! www.kcl.ac.uk/jobs/109186-...
kcl.ac.uk
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Seth Coffelt @coffeltlab.bsky.social · 07/02/2025
#hiring #postdoc We are looking for a postdoc to work on anti-tumor gamma delta T cells in breast cancer metastasis mouse models. Apply here: www.gla.ac.uk/explore/jobs...
gla.ac.uk
University of Glasgow - Explore - Jobs at Glasgow - Appointments - Research Associate (Breast Cancer Now) [164192]Search iconClose menu iconMenu icon bar 1Menu icon bar 2Menu icon bar 3
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Adrian Liston @labliston.bsky.social · 19/01/2025
#PhD researchers - want to build your #career options for post-PhD? This article provides you the necessary goals and timeline to ensure you have a good range of career options after you graduate. 🧵1/4 @immunolcellbiol.bsky.social with @makaroff.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
PhD training is incredibly versatile, with the possibility of leading to a myriad of downstream careers. However, it is often only in retrospect that the options and optimal strategies behind your ca...
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Madhvi Menon @madhvimenon.bsky.social · 16/01/2025
🚨 The Menon lab is hiring a postdoc! Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social Please help spread the word #ImmunoSky www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate in Mucosal Immunology :Manchester
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Pedro Papotto @ph-papotto.bsky.social · 15/01/2025
If you like parasites and gamma delta T cells, don't miss out on my webinar tomorrow (16/01) @ 5pm GMT! I'll be talking about our recently posted preprint! 👇🏼 www.biorxiv.org/content/10.1...
biorxiv.org
Migratory dermal γδ T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection
Many helminth parasites migrate through multiple host organs during infection but how immunity is regulated across these tissues is still poorly understood. To investigate the cellular and molecular a...
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Reposted by Pedro Papotto
Tara Sutherland @drtesutherland.bsky.social · 13/01/2025
Still time to apply to join our lab in Aberdeen as a post-doc, in a well-funded position. If you're interested in immune-ECM cross talk and want to use cutting edge spatial technologies, apply now. www.abdnjobs.co.uk/vacancy/rese...
abdnjobs.co.uk
Research Fellow (IMS301RX) | University of Aberdeen
The Sutherland lab, based at the University of Aberdeen, studies lung diseases at the interface between immunology and extracellular matrix biology. We are seeking to appoint a highly motivated, creat...
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Doug Dyer @douglaspdyer.bsky.social · 07/01/2025
Please spread the word and sign up for our exciting spring meeting in Nottingham with amazing speakers on the topic of ECM, immunity and infection. An exciting and developing field! paacr4.wixsite.com/bsmb-spring2...
paacr4.wixsite.com
Home | BSMBSpring2025
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γδ T cell Forum @forum-gd.bsky.social · 11/01/2025
Please join us for our January #GDTcellClub #gdTcells webinar with talks by Drs. Pedro Papotto and Victoria Stary. Jan 16 @ 12pm (New York) | 5pm (London) nyulangone.zoom.us/j/9589051706... Zoom ID: 958 9051 7066 Passcode: 369081 @payalyokota.bsky.social @ph-papotto.bsky.social
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Hepworth Lab @hepworth-lab.bsky.social · 10/01/2025
Exciting new pre print out now from @ph-papotto.bsky.social and @profjudiallen.bsky.social... Bluesky-orial below!
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Pedro Papotto @ph-papotto.bsky.social · 10/01/2025
What a great way to start this account and end the week: our preprint describing how dermal γδ T cells mediate a skin-lung axis during parasite infection in mice is online! I'm excited to show the findings of my main postdoc project with @profjudiallen.bsky.social!🧵👇 www.biorxiv.org/content/10.1...
biorxiv.org
Migratory dermal gamma delta T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection
Many helminth parasites migrate through multiple host organs during infection but how immunity is regulated across these tissues is still poorly understood. To investigate the cellular and molecular a...
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Reposted by Pedro Papotto
bioRxiv Immunology @biorxiv-immuno.bsky.social · 09/01/2025
Migratory dermal gamma delta T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection www.biorxiv.org/content/10.1101/202…
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British Society for Immunology @britsocimm.bsky.social · 08/01/2025
Ready to decode #omics to boost your #immunology research? 🧬 Learn the essentials of #bioinformatics and data visualisation on our highly-rated online 'Omic data analysis using #R' course 🤩 Limited spots available! Register now 👉 bit.ly/3BZOnSQ
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Kathryn Else @kathelse.bsky.social · 19/12/2024
Interested in immune responses to parasites? Mark Viney, James Hewitson and I have an exciting PhD project available : BBSRC NWD CASE: The role of co-infections in modulating anti-nematode immune responses Do get in touch if interested! urldefense.com/v3/__https:/...
urldefense.com
BBSRC NWD CASE: The role of co-infections in modulating anti-nematode immune responses at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD CASE: The role of co-infections in modulating anti-nematode immune responses at University of Liverpool, listed on FindAPhD.com
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James Hewitson @minsterbantam.bsky.social · 19/12/2024
www.findaphd.com/phds/project...
findaphd.com
BBSRC NWD CASE: The role of co-infections in modulating anti-nematode immune responses at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD CASE: The role of co-infections in modulating anti-nematode immune responses at University of Liverpool, listed on FindAPhD.com
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Edelblum Lab @edelblumlab.bsky.social · 17/12/2024
Recently finished your PhD or plan to in early 2025 and love #Tcell biology, particularly #gdTcells? We're recruiting a #NIDDK-funded #postdoc @sinaiimmuno.bsky.social! We'd love to have an #immunologist with expertise in #GIsky or #IBDsky join our team. bit.ly/4izpZLj #Immunosky
bit.ly
Postdoctoral Fellow-MSH-20093-049 in New York, NY | Mount Sinai Health Systems
Mount Sinai is hiring a Postdoctoral Fellow-MSH-20093-049 in New York, NY. Review all of the job details and apply today!
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Worboys Lab @worboyslab.bsky.social · 13/12/2024
Studentships available in the lab in the BBSRC NWD scheme (www.bmh.manchester.ac.uk/study/resear...) 1. Looking at the nanoscopic arrangement of chemokine-matrix interactions (with @douglaspdyer.bsky.social) #ImmunoSky #Immunomatrix
bmh.manchester.ac.uk
BBSRC NWDP projects | Biology, Medicine and Health | University of Manchester
Browse all of the currently available projects for the BBSRC North West Doctoral Programme in Bioscience at The University of Manchester.
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Henry McSorley @henrymcsorley.bsky.social · 12/12/2024
PhD available in the excellent @peronalab.bsky.social of Georgia Perona-Wright. The only downside of the PhD for the student is that I will also be involved. Its a cool project and will be a fun collaboration!
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