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Center for Cancer Immunotherapy and Immunobiology

@ccii-kyoto.bsky.social
869 followers 733 following 107 posts

Conquering cancer by advancing immunotherapy. The CCII is a research center at Kyoto University, led by Nobel Laureate Prof Tasuku Honjo. www.ccii.med.kyoto-u.ac.jp/en

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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 13/08/2026
CCII's Toshiyasu Suzuki introduces guest speaker Jun Ishihara (Imperial College) who spoke on "Improving Efficacy and Safety of Immune Checkpoint Inhibitors, Cytokine Therapy, and CAR-T Cells via Tumour Collagen-Targeted Drug Delivery System" www.ccii.med.kyoto-u.ac.jp/en/event/the...
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Reposted by Center for Cancer Immunotherapy and Immunobiology
Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 31/07/2026
The high level of heterogeneity of immune cells, (Kenji Chamoto) says, “is likely an eternal challenge in immunology.”'
nature.com
What’s your name, immune cell? - Nature Methods
Groups of immunologists are advancing recommendations to address nomenclature challenges in their subfields.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 31/07/2026
Visiting Prof. Thiago Carvalho @cyrilpedia.bsky.social in the second session of a hands-on workshop for CCII PhD students on writing introductions, abstracts & cover letters. www.ccii.med.kyoto-u.ac.jp/en/
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 31/07/2026
The high level of heterogeneity of immune cells, (Kenji Chamoto) says, “is likely an eternal challenge in immunology.”'
nature.com
What’s your name, immune cell? - Nature Methods
Groups of immunologists are advancing recommendations to address nomenclature challenges in their subfields.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 29/07/2026
What's in a name? Quite a lot: for cancer immunotherapy, it is vital that researchers & clinicians know when they are talking about the same cells (or not). CCII's Kenji Chamoto participated in this effort to standardise T cell nomenclature. #Immunology @natrevimmunol.nature.com
nature.com
Guidelines for T cell nomenclature - Nature Reviews Immunology
This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomenclature that is designed to be brief and flexible and to avo...
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Reposted by Center for Cancer Immunotherapy and Immunobiology
JAMA @jama.com · 27/07/2026
🔖 Bookmark now, reference later: Most #ThyroidCancer cases are well differentiated and asymptomatic, and surgery with or without #RadioactiveIodine is curative in most tumors >1 cm. Cite this #JAMAReview: ja.ma/4yI1vHC
JAMA Review: Thyroid Cancer. Diagram of antiangiogenic and targeted therapies in thyroid carcinoma. Various inhibitors (e.g., Selpercatinib, Sorafenib) target molecular pathways (RET, BRAF, VEGFR) to decrease tumor growth, induce apoptosis, and restore differentiation.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 27/07/2026
'Were it not for the imperative to turn more than a trillion dollars of losses into a profit, we would not have the aggressive, site-destroying scraping epidemic. Nor would we see AI crammed into every part of every product and service we use.' pluralistic.net/2026/07/24/s...
pluralistic.net
Pluralistic: AI solipsists and AI cynics (24 Jul 2026) – Pluralistic: Daily links from Cory Doctorow
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 23/07/2026
Following the success of last year, Four Seasons Hotel Kyoto is honoured to host the “Terry Fox Run 2026,” a charity event dedicated to supporting the Center for Cancer Immunotherapy and Immunobiology (CCII). www.ccii.med.kyoto-u.ac.jp/en/2026/07/1...
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Thiago Carvalho @cyrilpedia.bsky.social · 22/07/2026
You might be interested in this paper fm last year by my @ccii-kyoto.bsky.social colleague Kenji Chamoto et al, making the for neoantigens that activate both CD4 & CD8 rupress.org/jem/article/...
rupress.org
Chimeric MHC class I– and II–restricted non-self epitopes broaden antitumor T cell reactions
We identified peptide sequence principles that drive dendritic cell maturation and broaden tumor-reactive T cell clones, even with non-tumor sequences. The
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 23/07/2026
Following the success of last year, Four Seasons Hotel Kyoto is honoured to host the “Terry Fox Run 2026,” a charity event dedicated to supporting the Center for Cancer Immunotherapy and Immunobiology (CCII). www.ccii.med.kyoto-u.ac.jp/en/2026/07/1...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 21/07/2026
Day 3 of Salvatore Cosentino's CCII Workshop on Data Sharing and Management for Scientists. www.ccii.med.kyoto-u.ac.jp/en/event/cci...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 15/07/2026
CCII Visiting Professor Thiago Carvalho @cyrilpedia.bsky.social kicks off a series of sessions for graduate students on how to write the introduction to scientific manuscripts www.ccii.med.kyoto-u.ac.jp
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/07/2026
Thanks to Cornelia Weyand (Mayo Clinic/Stanford) for visiting Kyoto & CCII & giving the 50th CCII Seminar on “The Hidden Risk of Immune Youth in #Autoimmune Disease”. www.ccii.med.kyoto-u.ac.jp/event/event_...
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Reposted by Center for Cancer Immunotherapy and Immunobiology
Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 22/06/2026
At @cruk-mi.bsky.social, Santiago Zelenay @santiagozelenay.bsky.social introduces CCII vice director Sidonia Fagarasan, who spoke on metabolic effects on cancer #immunotherapy.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 21/07/2026
Day 3 of Salvatore Cosentino's CCII Workshop on Data Sharing and Management for Scientists. www.ccii.med.kyoto-u.ac.jp/en/event/cci...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 15/07/2026
CCII Visiting Professor Thiago Carvalho @cyrilpedia.bsky.social kicks off a series of sessions for graduate students on how to write the introduction to scientific manuscripts www.ccii.med.kyoto-u.ac.jp
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/07/2026
Thanks to Cornelia Weyand (Mayo Clinic/Stanford) for visiting Kyoto & CCII & giving the 50th CCII Seminar on “The Hidden Risk of Immune Youth in #Autoimmune Disease”. www.ccii.med.kyoto-u.ac.jp/event/event_...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 23/06/2026
Cornelia Weyand (Mayo Clinic/Stanford) will visit Kyoto & CCII on July 6th to speak about “The Hidden Risk of Immune Youth in #Autoimmune Disease”. It will mark our 50th CCII Seminar 🎂 #Immunology www.ccii.med.kyoto-u.ac.jp/event/event_...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 22/06/2026
At @cruk-mi.bsky.social, Santiago Zelenay @santiagozelenay.bsky.social introduces CCII vice director Sidonia Fagarasan, who spoke on metabolic effects on cancer #immunotherapy.
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ASHBi at Kyoto University @ashbi-kyotou.bsky.social · 01/06/2026
📢 Upcoming Workshop! Registration is still open for our upcoming ASHBi workshop. Don't miss out on the latest research! 📅 Date: June 22–23, 2026 📍 Venue: Nitori Hall, CCII, Kyoto Univ. 👉 Sign up: forms.gle/BWX876ymrwf4... 🔗 Event details: ashbi.kyoto-u.ac.jp/event/event-...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 05/06/2026
Dorina Avram (Moffitt Cancer Center) at CCII, discussing the “Control of Exhaustion and Stemness Programs in Tumor Infiltrating Lymphocytes and Opportunities for Response Improvement in Adoptive Cell Therapy” www.ccii.med.kyoto-u.ac.jp/en/event/eve... #Immunology #Immunotherapy
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 25/05/2026
New fm CCII researchers Katsuhiro Ito, Kenji Chamoto , Tomonori Yaguchi et al: "Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancer" #Immunology #Immunotherapy @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancer - Nature Communications
Tumor-reactive T cells (TR-T) in the peripheral blood of cancer patients undergo phenotypic changes during immune checkpoint inhibitor (ICI) therapy, which might predict therapeutic outcomes. Here aut...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 23/05/2026
June 1st at CCII, Dorina Avram on "Control of Exhaustion and Stemness Programs in Tumor Infiltrating Lymphocytes and Opportunities for Response Improvement in Adoptive Cell Therapy" #Immunology www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 22/05/2026
Thanks to Gabriel Nunez for visiting CCII & giving a seminar on "Microbiota-Immune Interactions in Intestinal Inflammatory Disease" #Immunology www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 16/04/2026
After two days on how to generate images, Stanford's Guolan Lu guided CCII workshop participants through what is arguably the most significant bottleneck: how to analyse all the resulting data (pic by @hiroshi-ichise.bsky.social) #Imaging #Immunology www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Thiago Carvalho @cyrilpedia.bsky.social · 16/04/2026
With @hiroshi-ichise.bsky.social, closing the @ccii-kyoto.bsky.social workshop on advanced imaging and image analysis in Kyoto. Thanks to Guolan Lu (Stanford), @iannaconelab.bsky.social, Andrea Radtke (Leica), Yuki Sugiura (CCII), and Johanne T. Jacobsen for great lectures and practicals!
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 15/04/2026
A Brief History of Everything (in imaging) with Oslo University's Johanne Tracey Jacobsen at CCII's workshop on Advanced Tissue Imaging and Image Analysis, followed by hands on work for the participants. #Immunology #Imaging www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 15/04/2026
A Brief History of Everything (in imaging) with Oslo University's Johanne Tracey Jacobsen at CCII's workshop on Advanced Tissue Imaging and Image Analysis, followed by hands on work for the participants. #Immunology #Imaging www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 14/04/2026
New paper from CCII researchers Masaki Tajima, Sidonia Fagarasan et al: a purine salvage pathway that helps CD8 T cells cope with metabolic stress and fend off ferroptosis. #Immunology #Metabolism @natimmunol.nature.com www.nature.com/articles/s41...
nature.com
Purine salvage pathway protects CD8+ T cells from metabolic stress - Nature Immunology
Tajima et al. show that a transient or continuous high-fat diet induces metabolic changes in CD8+ T cells that lead to increased vulnerability to ferroptosis and reduced antitumor responses.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 13/04/2026
Matteo Iannacone @iannaconelab.bsky.social gave a tour de force presentation on liver immunity, hosted by @hiroshi-ichise.bsky.social as part of the CCII workshop on Advanced Tissue Imaging & Image Analysis #Immunology #TissueImmunity www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 13/04/2026
Matteo Iannacone @iannaconelab.bsky.social gave a tour de force presentation on liver immunity, hosted by @hiroshi-ichise.bsky.social as part of the CCII workshop on Advanced Tissue Imaging & Image Analysis #Immunology #TissueImmunity www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 20/03/2026
CCII's Kenji Chamoto introduces guest speaker Florent Ginhoux, who spoke on the heterogeneity of tumor associated macrophage #Immunology #Kyoto www.ccii.med.kyoto-u.ac.jp/en/
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Dr. Sunny Shin @sunnyshinlab.bsky.social · 12/03/2026
Deadline extended to March 27th for the CSHA conference on Bacterial Infection & Host Defense May 11-15, 2026! We have a fantastic list of speakers and opportunities for abstract talks. For full details, please visit the conference webpage: www.csh-asia.org?content/2975. Hope to see you in Suzhou!
Flyer for CSHA Conference on Bacterial Infection & Host Defense
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Aegean Conferences, Inc. @aegeanconf.bsky.social · 12/03/2026
⏰ Reminder: There’s still time to register & submit an abstract for the 21st International Conference on Innate Immunity! 🎓 Travel awards available 📅 May 22–27, 2026 | 📍 Kalimera Kriti Hotel & Conference Center 🇬🇷 #InnateImmunity #Immunology aegeanconferences.org/src/App/conf...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 13/03/2026
Our Imaging workshop organizer, Hiroshi Ichise, will be joining CCII this spring. You can read Hiroshi's recent work with Ron Germain, 'Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection' (and see the beautiful images) 👇 www.science.org/doi/abs/10.1...
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Reposted by Center for Cancer Immunotherapy and Immunobiology
International Union of Immunological Societies @iuis-online.bsky.social · 13/03/2026
🧫 Working in pediatric infectious diseases? IIC 2026 takes place June 23–25, 2026, in Oxford, UK. Plenary sessions on key topics in pediatric infection, with lectures, case rounds & debate. Learn more: loom.ly/Qr7bMHM #ImmunologyWithoutBorders
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 13/03/2026
Our Imaging workshop organizer, Hiroshi Ichise, will be joining CCII this spring. You can read Hiroshi's recent work with Ron Germain, 'Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection' (and see the beautiful images) 👇 www.science.org/doi/abs/10.1...
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Reposted by Center for Cancer Immunotherapy and Immunobiology
Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 12/03/2026
Register for April's CCII Workshop on Advanced Tissue Imaging & Image Analysis, here in Kyoto. Org. by Hiroshi Ichise & supported by Leica. Invited faculty: Matteo Iannacone (San Raffaele), Johanne Tracey Jacobsen (Oslo), Guolan Lu (Stanford), Yuki Sugiura (CCII) & Andrea Radtke (Leica). It's free!
ccii.med.kyoto-u.ac.jp
CCII Workshop: Advanced Tissue Imaging and Image Analysis|Events|Center for Cancer Immunotherapy and Immunobiology
Detailed program information will be available soon. Please stay tuned.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 12/03/2026
Register for April's CCII Workshop on Advanced Tissue Imaging & Image Analysis, here in Kyoto. Org. by Hiroshi Ichise & supported by Leica. Invited faculty: Matteo Iannacone (San Raffaele), Johanne Tracey Jacobsen (Oslo), Guolan Lu (Stanford), Yuki Sugiura (CCII) & Andrea Radtke (Leica). It's free!
ccii.med.kyoto-u.ac.jp
CCII Workshop: Advanced Tissue Imaging and Image Analysis|Events|Center for Cancer Immunotherapy and Immunobiology
Detailed program information will be available soon. Please stay tuned.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/03/2026
Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity” For more info. 👇 #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Thiago Carvalho @cyrilpedia.bsky.social · 09/03/2026
Brown was an early mentor to Tasuku Honjo, who's always acknowledged him (including in his Nobel lecture over 4 decades later, on a completely different topic) When we were creatin a small exhibition here in @ccii-kyoto.bsky.social, Prof Honjo insisted that it include Don Brown (pic is from a panel)
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/03/2026
Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity” For more info. 👇 #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/event/eve...
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Journal of Experimental Medicine @jem.org · 27/01/2026
MHC one–two punch knocks out #cancer. Amir Ghorbani and Jonathan Yewdell @niaidnews.bsky.social discuss new study by Zhang, Chamoto and colleagues @ccii-kyoto.bsky.social (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/... #TumorImmunology #Immunotherapy
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/01/2026
The Chamoto lab at CCII works on the interplay of metabolism, ageing, and immunity in the host response to tumors. Find out more about their research here 👇 www.ccii.med.kyoto-u.ac.jp/en/research/...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/01/2026
New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com #Immunology #Immunotherapy #Metabolism www.nature.com/articles/s41...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 09/01/2026
New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com #Immunology #Immunotherapy #Metabolism www.nature.com/articles/s41...
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Thiago Carvalho @cyrilpedia.bsky.social · 31/12/2025
Here at @ccii-kyoto.bsky.social we had a workshop with @victora.bsky.social @danmucida.bsky.social Angelina Bilate (Rockefeller) & Carolina Lucas (Yale) where I asked them to discuss with the students & postdocs failed projects & negative results, including when to walk away from a project.
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 17/12/2025
CCII's Sidonia Fagarasan & Kenji Chamoto recently discussed recent advances in tumor #metabolism & #immunity at the 2nd @csisingapore.bsky.social – Kyoto University Joint Symposium. www.ccii.med.kyoto-u.ac.jp/en/2025/11/2...
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 23/12/2025
Senior Editor Zoltan Fehervari @nature.com recently stopped by CCII to discuss scientific publishing, some of its myths & legends, and what makes for a "good" paper. #ScientificPublishing #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/events/
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Center for Cancer Immunotherapy and Immunobiology @ccii-kyoto.bsky.social · 27/12/2025
'The deal, announced on December 22, is to be signed off officially in 2026, but Japanese researchers and companies can already apply for calls starting in January and join projects on an equal footing with partners in the EU and other associated countries.' sciencebusiness.net/news/horizon...
sciencebusiness.net
Japan to join Horizon Europe, strengthening EU role in global science
Japan has agreed to join Horizon Europe, becoming the biggest country yet to associate to the EU’s €93.5 billion research and innovation programme. The development confirms the EU’s emerging role as a...
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