Sign in

Hepworth Lab

@hepworth-lab.bsky.social
960 followers 513 following 55 posts

Mucosal Immunology Lab at the University of Manchester

PostsRepliesMedia
Hepworth Lab @hepworth-lab.bsky.social · 15/09/2026
Final bump for our two PDRA positions that close end of week. Important info for anyone who may be unsure, these positions are open to visa sponsorship for foreign nationals (despite incorrect wording originally included in the adverts)... so positions open to candidates far and wide!
012
Hepworth Lab @hepworth-lab.bsky.social · 08/09/2026
Super exciting meeting in London at end of month, great lineup of speakers at interface of environment and immunology. Registration is free and places still left - come and present your work (poster slots available)
011
Hepworth Lab @hepworth-lab.bsky.social · 24/08/2026
We have a Research Technician post that has just gone live (closing 18/09/26). Ideal for someone looking to build their research experience before a PhD or other scientific role. Details below - please share via your networks: www.jobs.manchester.ac.uk/Job/JobDetai...
032
Hepworth Lab @hepworth-lab.bsky.social · 17/08/2026
HUGE news in Manchester. Excited to welcome @slg1717.bsky.social and her lab to the institute!
053
Reposted by Hepworth Lab
Tracy Hussell @tracyh9494.bsky.social · 17/08/2026
The Becker moves on to a bright future with the fantastic appointment of Sarah Gaffen. A brilliants scientist and team player. Im thrilled the Becker is in safe hands.
093
Hepworth Lab @hepworth-lab.bsky.social · 07/08/2026
🚨 We are hiring!! 🚨 2 postdoctoral research associate roles available in our lab - adverts now open, closing date 18/09/26. Details below - please spread the word far and wide!
jobs.manchester.ac.uk
Postdoctoral Research Associate in Immunology:Oxford Road
186
Reposted by Hepworth Lab
Lydia Becker Institute @lydiabeckeriii.bsky.social · 05/08/2026
Discover the latest from the Becker! Our August newsletter features new grant awards, new networks in Immuno-Biotechnology and Cancer Immunology, ECR highlights, community updates, and our latest publications. Read the full issue: documents.manchester.ac.uk/display.aspx... #ImmunoSky
011
Reposted by Hepworth Lab
Mahima Swamy @mahimaswamy.bsky.social · 04/08/2026
Excited to announce I am starting as Professor of Immunology at the University of Manchester this week! I am #hiring a #postdoc in Manchester, to work on human intestinal lymphocytes in #Coeliac disease, please get in touch if interested. @lydiabeckeriii.bsky.social
static.klipy.com
Camp Summer2023: We're Hiring
ALT: Camp Summer2023: We're Hiring
3207
Hepworth Lab @hepworth-lab.bsky.social · 31/07/2026
Incredibly exciting news to be welcoming @mahimaswamy.bsky.social to Manchester. Looking forward to discussions, collaborations and hearing more about all the exciting work coming out of the Swamy lab!!!
032
Hepworth Lab @hepworth-lab.bsky.social · 14/05/2026
Interesting new review article from former lab member @kingji.bsky.social
020
Reposted by Hepworth Lab
Mucosal Immunology @mucosalimmunol.bsky.social · 13/05/2026
Cytokine networks driving eosinophil functional heterogeneity www.mucosalimmunology.org/article/S193...
095
Reposted by Hepworth Lab
Doug Dyer @douglaspdyer.bsky.social · 01/05/2026
delighted to share our new pre-print developing label-free glycosaminoglycan analysis of diverse complex biological samples, led by @h-davies-s.bsky.social working closely with David Knight and Rebecca Miller alongisde our recent recruit Samie Dalgarno www.biorxiv.org/content/10.6...
biorxiv.org
4177
Reposted by Hepworth Lab
Journal of Experimental Medicine @jem.org · 27/04/2026
New study from @mengzelyu.bsky.social in the Gregory F. Sonnenberg lab @weillcornell.bsky.social reveals that #microbiota-specific RORγt+ regulatory T cells are uniquely restrained by B7 costimulation. rupress.org/jem/article/... #MucosalImmunology #Tolerance
021
Hepworth Lab @hepworth-lab.bsky.social · 27/04/2026
Congrats to former lab member @rosertp.bsky.social on this new work in @jem.org
142
Reposted by Hepworth Lab
Journal of Experimental Medicine @jem.org · 27/04/2026
New study: @rosertp.bsky.social, Bashour, Filipska, et al (@victorgreiff.bsky.social & Cerutti labs, Uni Oslo & @researchmar.bsky.social) show IgD responses involve a heterogenous pop. of IgD class-switched memory #Bcells from epithelial areas of aerodigestive mucosa. rupress.org/jem/article-...
0138
Reposted by Hepworth Lab
David Posner, PhD @davidposner.bsky.social · 30/03/2026
@hepworth-lab.bsky.social new paper alert. Matt and I wrote a research highlight about recent papers that describe mechanisms of ILC2-neuron crosstalk. If you're interested in reading it, check it out! onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
Emerging roles of ILC2 in neuronal crosstalk across organs. In a series of studies published in 2025, ILC2 were shown to regulate nervous system function across a range of organs across the body. Wit...
065
Reposted by Hepworth Lab
Lydia Becker Institute @lydiabeckeriii.bsky.social · 06/03/2026
To celebrate #InternationalWomensDay, we’re honouring our namesake, Lydia Becker. A pioneer for suffrage and a dedicated botanist, she fought for women’s right to scientific education. We continue her mission by championing the brilliant women leading the way in immunology research. #IWD2026
Image of Lydia Becker, suffragist, scientist, trailblazer, International Women's Day 2026, Lydia Becker Institute of Immunology and Inflammation. Image credit: @realmancsy
011
Reposted by Hepworth Lab
Lydia Becker Institute @lydiabeckeriii.bsky.social · 04/03/2026
New research from the @hepworth-lab.bsky.social lab and @gjbrainresearch.bsky.social reveals how stroke impacts the gut immune system and microbiome. By identifying changes in intestinal IgA and immune crosstalk, investigators are uncovering new ways to treat complications. tinyurl.com/48v4jy9e
tinyurl.com
Stroke’s Reach Beyond the Brain: New Study Reveals Impact on the Gut Immune System and Microbiome
New research from the Lydia Becker Institute reveals how stroke impacts the gut-brain axis, altering IgA antibodies and the microbiome.
041
Reposted by Hepworth Lab
Arthur Mortha @theonlylabever.bsky.social · 22/01/2026
Please share and distribute ILC6 6th International Conference on Innate Lymphoid Cells in Vancouver, BC Canada Abstract submission and registration are open: ilc6vancouver.com #immunosky #ILC6vancouver #ILC6 Lots of presenter spots available!!! Get those hot abstracts out.
042
Reposted by Hepworth Lab
Sarah Crome @sarahcrome.bsky.social · 22/01/2026
The new Crome Lab at BC Cancer is up and running — and we’re hiring! We’re recruiting a PDF for a newly funded project on ILCs & NK cells in Type 1 Diabetes, using spatial genomics and single-cell approaches. 🔗 jobs.phsa.ca/job/postdoct... #Immunology #SingleCell #SpatialGenomics #Type1Diabetes
jobs.phsa.ca
Postdoctoral Fellow - Innate Lymphoid Cells and Spatial Genomics in Type 1 Diabetes, Crome Lab, Terry Fox Laboratory - BC Cancer Vancouver | Working at Provincial Health Services Authority | Careers a...
Postdoctoral Fellow - Innate Lymphoid Cells and Spatial Genomics in Type 1 Diabetes, Crome Lab, Terry Fox Laboratory BC Cancer Vancouver, BC We are recruiting a highly motivated Postdoctoral Fellow to...
0910
Reposted by Hepworth Lab
Mucosal Immunology @mucosalimmunol.bsky.social · 22/01/2026
Trained ILC2 prevent IL-17-associated lung injury during helminth infection through a serotonin-dependent mechanism www.mucosalimmunology.org/article/S193...
172
Reposted by Hepworth Lab
Lydia Becker Institute @lydiabeckeriii.bsky.social · 10/12/2025
🏆 Huge congratulations to our Director Professor Tracy Hussell @tracyh9494.bsky.social who has been awarded the Nature 2025 Lifetime Achievement Award for Mentoring in Science for her exceptional support of emerging scientists. #ImmunoSky @nature.com sites.manchester.ac.uk/lydia-becker...
sites.manchester.ac.uk
Professor Tracy Hussell Receives Nature Lifetime Achievement Award for Mentoring in Science
Professor Tracy Hussell receives the 2025 Nature Lifetime Achievement Award for Mentoring in Science, recognising her outstanding support of early-career researchers.
0144
Reposted by Hepworth Lab
The University of Manchester @manchester.ac.uk · 26/11/2025
The Old Quad by night 🌙 📸@alderley_aerial_photography on Instagram
An aerial image of the Old Quad and Oxford road at night time
0112
Hepworth Lab @hepworth-lab.bsky.social · 25/11/2025
www.manchester.ac.uk/about/news/s...
manchester.ac.uk
Stroke scientists gather more evidence for presence of ‘gut-brain axis’
Research on mice by scientists at The University of Manchester has shed new light on why the guts’ immune system changes after a stroke and how it might contribute to gastro-intestinal problems.Publis...
0106
Hepworth Lab @hepworth-lab.bsky.social · 22/11/2025
New paper out from the lab, led by Maddy Hurry. We investigate how stroke leads to peripheral complications in the gut through dysregulation of IgA mediated host-commensal crosstalk. @lydiabeckeriii.bsky.social @diiirm.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Cerebral ischaemic stroke results in altered mucosal antibody responses and host-commensal microbiota interactions
Stroke is a devastating neurological event with a high risk of mortality that results in long-term sequalae that extend beyond the central nervous sys…
2124
Reposted by Hepworth Lab
Prof Sheena Cruickshank @sheencr.bsky.social · 14/11/2025
so excited to share our article in @nature.com Immunology on the many challenges of climate change has for our immune function, infection susceptibility and disease and the need for new ways to research this. Will do a thread later! 🧪 @lydiabeckeriii.bsky.social @exposomeimmunology.bsky.social
urldefense.com
The role of ecoimmunology in tackling the emerging threats of climate change and the exposome
Nature Immunology - Climate change creates a multitude of challenges over the human life-course, influencing our exposomes and shaping immune function — requiring researchers to consider...
04515
Reposted by Hepworth Lab
6th International Conference on Innate Lymphoid Cells @ilc6.bsky.social · 03/11/2025
BIG NEWS! The Innate Lymphoid Cell (ILC) 6 Meeting (ILC6) will take place on June 2nd-4th, 2026, in Vancouver! Keynotes include: Andrew McKenzie, Kazuyo Moro. ilc6vancouver.com #ILC6 #ILC6Vancouver #2026ILC6 (1/3)
195
Hepworth Lab @hepworth-lab.bsky.social · 05/11/2025
A few more weeks to apply for this postdoc in mucosal immunology and ILC biology, please share in your networks and with interested candidates.
064
Reposted by Hepworth Lab
Judi Allen @profjudiallen.bsky.social · 20/10/2025
Friday we celebrated our new MRC Centre of Research Excellence in Exposome Immunology: a joint venture with Oxford that we call MOXIE (Manchester-Oxford Immunology of the Exposome). This challenging adventure is off to a great start. @exposomeimmunology.bsky.social
0338
Hepworth Lab @hepworth-lab.bsky.social · 09/10/2025
Postdoc opportunity in the lab for a budding ILC biologist. Informal enquiries welcome - please spread the word. Ad closes in 4 weeks. www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate - mucosal immunology and innate lymphoid cell (ILC) biology:Oxford Road
The Hepworth laboratory within the Lydia Becker Institute of Immunology and Inflammation at the University of Manchester wish to appoint a laboratory-based Research Associate to an exciting project in mucosal immunology and innate lymphoid cell (ILC) biology.
175
Hepworth Lab @hepworth-lab.bsky.social · 01/10/2025
Nice article about the community of Lister fellows in Manchester!
051
Reposted by Hepworth Lab
Doug Dyer @douglaspdyer.bsky.social · 22/09/2025
We now have a very exciting technician post advertised as part of our long term Wellcome Trust funded team investigating the role of the glycocalyx during CNS inflammation. Supporint the lab, developing glycan analysis and research experience www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Technician in the Glyco-immunology (Dyer) Lab:Oxford Road
Include: background, duties, essential skills and experience, length of contract, full or part-time. Keep to 150 words.
0611
Reposted by Hepworth Lab
Dr Hannah Tompkins @hetompkins.bsky.social · 20/09/2025
So pleased to see our research out in #ScienceImmunology demonstrating that CLPs regulate airway remodelling during allergy 🫁 Really proud of the hard work and collaboration that went into this project 🫱🏼‍🫲🏽. Definitely one to check out for lovers of the immuno-matrix & pretty pictures👇🏼🔬
0123
Reposted by Hepworth Lab
Tara Sutherland @drtesutherland.bsky.social · 19/09/2025
Aberdeen is hiring - Neuroimmunology Lectureship! Really exciting opportunity to join our supportive, collaborative and multidisciplinary Institute to carry out cutting edge translation research. Not to mention the scenery in the North East of Scotland is amazing www.abdn.ac.uk/jobs/vacanci...
abdn.ac.uk
Lecturer in Neuroimmunology, Medicine, Medical Sciences & Nutrition (MED243A) | The University of Aberdeen
Browse and apply for current job openings at the University of Aberdeen across various schools, departments and roles, including admin and academic.
01011
Reposted by Hepworth Lab
Doug Dyer @douglaspdyer.bsky.social · 12/09/2025
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road
Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:
11818
Reposted by Hepworth Lab
David Posner, PhD @davidposner.bsky.social · 16/09/2025
New paper alert! 🎉 Check it out here: biorxiv.org/content/10.1... Here we show that intestinal bacterial, helminth and fungal challenges polarise CD4 T cell populations in the dural meninges.
biorxiv.org
Intestinal challenges shape the polarisation of protective dural memory CD4 T cells
The meninges house several innate and adaptive immune cell populations[1][1]–[3][2]. These predominantly localise within the dura mater and include gut-derived IgA-secreting plasma cells[4][3]. Whethe...
1145
Hepworth Lab @hepworth-lab.bsky.social · 09/09/2025
Following on from the PDRA adverts, we are also happy to announce the MRC Core in Exposome Immunology PhD scheme, details below. Reach out with any questions www.findaphd.com/phds/program... www.bmh.manchester.ac.uk/study/resear...
findaphd.com
FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester
Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester
032
Hepworth Lab @hepworth-lab.bsky.social · 08/09/2025
New Postdoc position as part of the recently awarded MRC Core in Exposome Immunology, led by Jo Konkel here @lydiabeckeriii.bsky.social. Job ad and more info below: www.jobs.manchester.ac.uk/Job/JobDetai... www.bmh.manchester.ac.uk/research/ins...
jobs.manchester.ac.uk
Research Associate in MRC CoRE in Exposome Immunology (Defining Acute and Chronic Mucosal Responses to Pollution Exposure):Oxford Road
Project Title: Defining Acute and Chronic Mucosal Responses to Pollution Exposure
01213
Reposted by Hepworth Lab
Kat Coyte @coytelab.bsky.social · 08/09/2025
closing at the end of this week!
0313
Reposted by Hepworth Lab
Kat Coyte @coytelab.bsky.social · 27/08/2025
Another PDRA position! Join our team exploring how the mammalian immune system shapes microbiome ecology & evolution, and vice versa. In collaboration with @hepworth-lab.bsky.social funded by the @wellcometrust.bsky.social www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate in Microbial Ecology:Oxford Road
02218
Reposted by Hepworth Lab
Ákos T Kovács @evolvedbiofilm.bsky.social · 14/08/2025
Cell Symposia: Host-microbiome dynamics May 10–12, 2026 | Bruges, Belgium by @cp-immunity.bsky.social @cp-cellhostmicrobe.bsky.social and @cp-trendsmicrobiol.bsky.social www.cell-symposia.com/microbiome-2...
23512
Reposted by Hepworth Lab
Lydia Becker Institute @lydiabeckeriii.bsky.social · 16/07/2025
🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases. #Exposome #ImmunoSky sites.manchester.ac.uk/lydia-becker...
sites.manchester.ac.uk
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A groundbreaking £50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.
23710
Reposted by Hepworth Lab
Judi Allen @profjudiallen.bsky.social · 16/07/2025
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...
ukri.org
Centre to study how exposome causes chronic inflammatory disease
A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
25815
Hepworth Lab @hepworth-lab.bsky.social · 16/07/2025
www.ukri.org/news/centre-...
ukri.org
Centre to study how exposome causes chronic inflammatory disease
A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
000
Hepworth Lab @hepworth-lab.bsky.social · 16/07/2025
Big news! Manchester, together with colleagues in Oxford, have been awarded an MRC CoRE in Exposome Immunology!! Exciting times ahead to uncover how pollution and other environmental factors worsen inflammatory diseases!!
0185
Reposted by Hepworth Lab
Waggoner Lab @labwaggoner.bsky.social · 16/06/2025
ILC3s are a RORγt+ APC that sense the microbiota through STING to induce microbiota-specific Treg cells www.cell.com/immunity/ful... @cp-immunity.bsky.social
164
Hepworth Lab @hepworth-lab.bsky.social · 14/04/2025
So cool to see our recent review highlighted on the cover of @mucosalimmunol.bsky.social !!
1131
Reposted by Hepworth Lab
Emily White @emily-white.bsky.social · 11/04/2025
Come and work with me! The Nature Micro team is expanding and we're looking for someone to champion microbial ecology, plant micro & related areas for the journal Knowledge of microbial ecology/plant micro is desirable but we're open to applications from all microbiologists Link below 👇
110199
Reposted by Hepworth Lab
D’Agostino Lab @dagostinolab.bsky.social · 07/04/2025
Our latest study @science.org #Immunology on perception of #hunger and #immunity. #BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones. @ukri.org @fbmh-uom.bsky.social www.science.org/doi/10.1126/...
science.org
Brain sensing of metabolic state regulates circulating monocytes
Brain-initiated hunger signals control circulating monocyte dynamics.
14413
Hepworth Lab @hepworth-lab.bsky.social · 08/04/2025
A pleasure to be a part of this study with @dagostinolab.bsky.social revealing how hunger sensing neurons in the brain act to modulate circulating monocyte levels. Out now in #scienceimmunology
092