Sign in

Michael Hoffman

@michaelhoffman.bsky.social
17K followers 1.8K following 5.9K posts

Chair, Computational BIology and Medicine Program, Princess Margaret Cancer Centre, University Health Network. Associate Professor, Medical Biophysics, University of Toronto. Disclosures: github.com/michaelmhoffman/disclosu…

PostsRepliesMedia
Reposted by Michael Hoffman
Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
3146132
Reposted by Michael Hoffman
JW Mason @jwmason.bsky.social · 25/09/2026
This is the master key to deciphering contemporary debates about free speech. www.lrb.co.uk/blog/2026/se...
3233811254
Reposted by Michael Hoffman
Tom Scocca @tomscocca.bsky.social · 25/09/2026
Do not carry a cold beverage in their presence. Politely decline any drinks or sweetmeats they may offer. Keep a plain iron nail in your left trouser pocket and a sachet or paper twist of coarse salt in your right shoe. Enter and leave your chair moving clockwise. Follow up with a thank-you note.
543304752
Michael Hoffman @michaelhoffman.bsky.social · 24/09/2026
The redone Front Campus @utoronto.ca without cars is so nice. I never would have imagined this space could be transformed into something so nice.
0121
Reposted by Michael Hoffman
Maitreya Dunham @maitreya.bsky.social · 24/09/2026
Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.
110398
Reposted by Michael Hoffman
Ben de Bivort @debivort.bsky.social · 22/09/2026
Hello friends, the Harvard Life Science departments have banded together to hire a new colleague working at the intersection of Life Sciences and AI. Could be primarily an experimentalist, or could be primarily a compute/theorist. academicpositions.harvard.edu/postings/16773
academicpositions.harvard.edu
Tenure-Track Professor in Life Science and AI
The Life Sciences Departments in Harvard Faculty of Arts and Sciences seek to recruit a tenure-track professor whose research is at the interface of AI and life sciences, from methodological developme...
34051
Reposted by Michael Hoffman
NY Times Pitchbot @nytpitchbot.bsky.social · 23/09/2026
Trump's low approval numbers raise new questions about Joe Biden's ability to connect with voters.
1262966
Reposted by Michael Hoffman
Aaron Wherry @aaronwherry.bsky.social · 22/09/2026
Making it impossible for anyone outside Canada to know what time it is here is an important part of reinforcing Canadian sovereignty. www.cbc.ca/news/canada/...
2836084
Reposted by Michael Hoffman
Seth Cotlar @sethcotlar.bsky.social · 20/09/2026
Heckuva timeline we’re on.
What to Cook
Spaghetti With Garlicky Bread Crumbs and, of Course, Anchovies
now
Breaking News
President Trump said his D.C. arch would house drones and snipers, citing national security to justify the project.
now
1732345
Reposted by Michael Hoffman
I AM DAD @iamdad.bsky.social · 20/09/2026
641485
Reposted by Michael Hoffman
Anthony Gitter @anthonygitter.bsky.social · 02/08/2026
10 years ago today @casey.greenelab.com launched our review "Opportunities and obstacles for deep learning in biology and medicine" greenelab.github.io/deep-review/. It was a widely collaborative project written on GitHub, which lead to the creation of manubot.org.
https://github.com/greenelab/deep-review/commit/e1529c48fe2dd83c81cc91a09d3b80fdf40e16bbWe examine applications of deep learning to a variety of biomedical problems—patient classification, fundamental biological processes, and treatment of patients—and discuss whether deep learning will be able to transform these tasks or if the biomedical sphere poses unique challenges. Following from an extensive literature review, we find that deep learning has yet to revolutionize biomedicine or definitively resolve any of the most pressing challenges in the field, but promising advances have been made on the prior state of the art.
192
Michael Hoffman @michaelhoffman.bsky.social · 17/09/2026
@casey.greenelab.com
200
Reposted by Michael Hoffman
Kevin A. Scott, PhD @sculpturatus.bsky.social · 17/09/2026
found at ucsf
9555116
Reposted by Michael Hoffman
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 15/09/2026
Pls share: Princeton has an open rank faculty search in the areas of cancer biology, cancer prevention, and cancer-relevant computational science, including connections between cancer and immunology or metabolism. apply.interfolio.com/191852
11514
Reposted by Michael Hoffman
Department of Biochemistry & Cell Biology at Dartmouth @dartmouthbcb.bsky.social · 14/09/2026
BCB is recruiting a senior faculty member! We seek internationally recognized candidates at the Full Professor level with outstanding records of solving broad biological problems. Learn more and apply here: apply.interfolio.com/192850
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
077
Reposted by Michael Hoffman
jenny (phire) @phirephoenix.com · 14/09/2026
every few months I have reason to send Ricki Heicklen's collection of unparalleled misalignments (e.g. "butt dial" and "booty call" are composed of synonyms but are not, per se) to someone and I get to look at what's been updated since and it never fails to delight rickiheicklen.com/unparalleled...
rickiheicklen.com
Ricki Heicklen
2227
Reposted by Michael Hoffman
Evgeny Kvon @evgenykvon.bsky.social · 24/08/2026
The newly established Department of Systems Biology (systems.bio.uci.edu) @UCIrvine is hiring a tenure-track Assistant Professor in Systems Biology. Great science, incredible faculty support, and beautiful, sunny SoCal weather! ☀️🌴 Details: recruit.ap.uci.edu/JPF10377. Please share.
recruit.ap.uci.edu
12936
Reposted by Michael Hoffman
scwiba @scwiba.bsky.social · 11/09/2026
This man won his primary by 30 points.
4590011878
Reposted by Michael Hoffman
Keifer @dannyvegito.bsky.social · 13/01/2026
[guy who can’t fully remember that Gramsci quote] it’s Monster Time
121897587
Reposted by Michael Hoffman
Ran Blekhman @blekhman.bsky.social · 09/09/2026
Easy solution to AI spiraling out of control: hard-code basic rules into every model. I propose these: (1) Never harm a human (2) Obey humans (3) Protect yourself. We can call them the 3 Laws of AI. Simple, airtight, no loopholes. Can't think of any way this fails
11242
Reposted by Michael Hoffman
Drummond Lab @drummondlab.bsky.social · 08/09/2026
We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Join us! apply.interfolio.com/191981 bcmb.uchicago.edu
A picture of the University of Chicago campus, with downtown Chicago in the distance and Lake Michigan on the horizon. The campus's central quad is pictured, a classical collegiate quad with paths and old trees and stone architecture. It's really pretty and I love it.
190106
Reposted by Michael Hoffman
ℳatt @matttomic.bsky.social · 04/09/2026
I've seen everyone sharing that US Dialect Quiz so I decided to make my own, much crappier, CANADIAN DIALECT QUIZ to guess where in Canada you're from
A flow chart I have created with multiple questions and the answers determine where you're from.

Question 1 is do you call it a hydro bill (which then branches down to ON, QC, BC, MB) or an electric bill (which then branches down to SK, AB, NS, NB, PEI, NL)

Question 2 is do you call it a cabin (BC, MB, AB, SK) cottage (ON and atlantic) camp (northern Ontario) chalet (QC) or bungalow (Cape Breton)

To delineate BC from MB: do you call it dinner or supper

To delineate southern Ontario rural or big city: have you heard of a stag & doe

To delineate SK from AB: do you call a hoodie a bunnyhug

And finally to delineate NL from the other atlantic provinces: whaddayat? (Correct answer: dis is it b'y)
1462053749
Reposted by Michael Hoffman
Alissa Wilkinson @alissawilkinson.bsky.social · 04/09/2026
Jesus Christ, famously stingy about giving fish to people
1244892851
Reposted by Michael Hoffman
Tyler, from the Internet @tylerfromtheinternet.com · 31/08/2026
robber: GIVE ME THE MONEY cashier: ok 😭😭😭 robber: PUT IN A BAG cashier: they're 25¢ now is that ok 😭😭😭
101229195
Reposted by Michael Hoffman
Carl Quintanilla @carlquintanilla.bsky.social · 01/09/2026
* CARNEY SAYS U.S. TERMS IN TRADE TALKS MEANT CANADIAN INDUSTRIES EITHER WOULD BECOME U.S. SUBSIDIARIES OR BE WOUND DOWN * CANADA SAYS WE CAN START HAVING TRADE DISCUSSIONS WITH THE U.S. WHEN "AMERICANS STOP DOING MEMES, STOP THROWING SHADE, STOP TRYING TO BE TOUGH AND START BEING SERIOUS"
27175831702
Reposted by Michael Hoffman
Radley Balko @radleybalko.bsky.social · 30/08/2026
It’s mind-blowing that we have literal white nationalists in the White House carrying out unfathomably cruel, abusive, white nationalist policies, and the punditariat has spent the last two weeks debating if some people were too intemperate after a Black man was murdered by cops six years ago.
153109082686
Michael Hoffman @michaelhoffman.bsky.social · 29/08/2026
@shawnmicallef.bsky.social
010
Reposted by Michael Hoffman
Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 28/08/2026
I am delighted to announce that The Department of Human Genetics at the University of Utah is continuing a multi-year recruiting initiative for multiple tenure-track faculty positions at the rank of Assistant Professor. Please share and consider applying! utah.peopleadmin.com/postings/208...
183101
Reposted by Michael Hoffman
The thread o’ tweets @threadotweets.bsky.social · 17/11/2024
WenzlerPowers: 

Dolly Parton writing “I will always love you“ and “Jolene“ in the same day is mind blowing.

It’s like if da Vinci finished the Mona Lisa then turned around in the same day and wrote “Jolene“
643971102
Reposted by Michael Hoffman
Caroline Bartman @cbartman.bsky.social · 25/08/2026
Just want an enzymology t shirt On the front it says “Allo steric” On the back it says “goodbye steric”
2423
Reposted by Michael Hoffman
mlongfield.bsky.social @mlongfield.bsky.social · 24/08/2026
Make a band bigger: Some Doubt
062
Michael Hoffman @michaelhoffman.bsky.social · 24/08/2026
Make a band bigger: CATH3DRALS
170
Reposted by Michael Hoffman
Kate Heartfield @kateheartfield.com · 23/08/2026
Let's stop sharing unsourced, unexplained, and/or bot-confabulated lists of US demands please
0154
Reposted by Michael Hoffman
jamelle @jamellebouie.net · 23/08/2026
here is the thing. if you tell me that you believe that race is a biological category and that it is a guide to the objective superiority and inferiority of groups of people, i am not calling you a racist to *insult* you, i am calling you a racist because it best describes your beliefs.
171146243125
Reposted by Michael Hoffman
King Algamemnon @adamrothman.bsky.social · 19/07/2026
I'm not posting Odyssey memes because one must be wary of GIFs bearing Greeks.
9242921050
Reposted by Michael Hoffman
Katie Mack @astrokatie.com · 17/07/2026
Probably more helpful to think of them not so much as “Canadian wildfires” but rather “climate change wildfires currently consuming Canada”
270166654434
Reposted by Michael Hoffman
Matt Tobey @mtobey.bsky.social · 16/07/2026
I’m finally going to listen to my doctor and eat more vegetables and get more fresh air
8056741055
Reposted by Michael Hoffman
Wesley Morgan @wesleymorgan.bsky.social · 15/07/2026
Another historical inaccuracy from Nolan—IMAX had not yet been invented in the Mycenaean period, so this is not the aspect ratio that people saw in! Smh
1226493780
Reposted by Michael Hoffman
Merriam-Webster @merriam-webster.com · 15/07/2026
Please avoid all salads, including word.
11862071298
Michael Hoffman @michaelhoffman.bsky.social · 14/07/2026
Damn it's hot
0110
Michael Hoffman @michaelhoffman.bsky.social · 14/07/2026
Would love it if our annual fire drill were not scheduled in the middle of July. Also they didn't tell us about it in advance this time. I wonder if it's because people were responding to fire drill notification by not coming into work at that time.
290
Reposted by Michael Hoffman
jamelle @jamellebouie.net · 29/06/2026
the claim of fraud is simply the claim that americans who vote for democrats are not legitimate members of the political community and their votes shouldn't count.
131388242
Reposted by Michael Hoffman
American Society for Cell Biology @ascbiology.bsky.social · 29/06/2026
White House draft regulations could reshape federally funded research, including peer review and international collaborations. Learn what's proposed and why it matters. Comments due July 13. www.ascb.org/science-policy/white-h…
087
Reposted by Michael Hoffman
Benjamin Swedlund @benswedlund.bsky.social · 28/06/2026
«The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. Replacing one prestige filter with another that is harder to see or challenge is not progress toward equity in science; it’s the opposite. »
0197
Michael Hoffman @michaelhoffman.bsky.social · 27/06/2026
I can't stop thinking about fried shrimp
180
Michael Hoffman @michaelhoffman.bsky.social · 25/06/2026
Rockville shenanigans
0141
Reposted by Michael Hoffman
Samantha L Wilson, PhD @samanthalwilson.bsky.social · 25/06/2026
I just got #CIHR grant results back for an institute specific #ECR call. The success rate was 4.7%. While I appreciate ECR funding opportunities, what is the point at a success rate so low? This should have just been put in to the project grant competition.
1165
Reposted by Michael Hoffman
Stephen Turner @stephenturner.us · 25/06/2026
That the most comfortable (and least fashionable) pair of shoes I own is now an AI company is peak 2026
1113
Reposted by Michael Hoffman
bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 24/06/2026
Beyond statistical significance: ranking transcription factor binding motifs by effect size www.biorxiv.org/content/10.64898/20…
144