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Michael Hoffman

@michaelhoffman.bsky.social
17K followers 1.8K following 5.9K posts

Chair, Computational BIology and Medicine Program, Princess Margaret Cancer Centre, University Health Network. Associate Professor, Medical Biophysics, University of Toronto. Disclosures: github.com/michaelmhoffman/disclosu…

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Reposted by Michael Hoffman
A.R. Moxon @juliusgoat.bsky.social · 03/10/2026
Hey, I’m just asking questions. Ignorant questions, bigoted questions, questions that have been repeatedly answered for many years. Sorry, but I’m not listening to answers right now; I’m far too busy asking questions. It’s called being intellectually curious.
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Tom Cox @dj-acid-reflux.bsky.social · 22/05/2026
When I used to write for The Guardian, every time I wrote the word “meow” the editors would change it to “miaow”. It used to really get on my wick. Don’t try to make my cats sound like your upper middle class London cats, you fuckers. My cats did not go to your posh cat schools. They say “meow”.
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okay Kelly @kmdoublev.bsky.social · 03/10/2026
sometimes I want to use the phrase 'as an empath' but I don't, because I know how it will make others feel
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Paul Cohen @paulecohen.bsky.social · 02/10/2026
i think it may be conscious
a photograph of a slide rule
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Mark Copelovitch @mcopelov.bsky.social · 01/10/2026
All possible through normal legislation:
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Michael Hoffman @michaelhoffman.bsky.social · 01/10/2026
Sorry to see this 😔
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Jeremy Berg @jeremymberg.bsky.social · 01/10/2026
From a discussion of updating a department website...
A photo with baby Yoda and adult Yoda with the caption "Could it be time for a new photo?"
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Jeffrey M Kidd @jeffreymkidd.bsky.social · 01/10/2026
Excited to share that my department has an open faculty search for an Assistant Professor! The search is broad, focused on candidates who plan to address fundamental questions in genetics and genomics. The due date is soon: Nov 13. You can apply through interfolio. apply.interfolio.com/190644
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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the hype @thehyyyype.bsky.social · 09/09/2026
[explaining social media to aliens] yeah you basically scroll a little screen for hours and get absolutely furious
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Ian Coldwater 🧊🚫 @lookitup.baby · 30/09/2026
BREAKING NEWS: “Do geese see God” is a palindrome
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Ellen Leffler @ellenleffler.bsky.social · 30/09/2026
My department at University of Utah is recruiting new faculty, with "Human" and "Genetics" broadly defined. It is a fantastic place to start a lab, with collaboration, creativity and conviviality encouraged. Applications due Oct 16. Please share and apply! utah.peopleadmin.com/postings/208...
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Michael Hoffman @michaelhoffman.bsky.social · 27/09/2026
Yikes!
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JW Mason @jwmason.bsky.social · 25/09/2026
This is the master key to deciphering contemporary debates about free speech. www.lrb.co.uk/blog/2026/se...
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Tom Scocca @tomscocca.bsky.social · 25/09/2026
Do not carry a cold beverage in their presence. Politely decline any drinks or sweetmeats they may offer. Keep a plain iron nail in your left trouser pocket and a sachet or paper twist of coarse salt in your right shoe. Enter and leave your chair moving clockwise. Follow up with a thank-you note.
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Michael Hoffman @michaelhoffman.bsky.social · 25/09/2026
wtf
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Michael Hoffman @michaelhoffman.bsky.social · 24/09/2026
The redone Front Campus @utoronto.ca without cars is so nice. I never would have imagined this space could be transformed into something so nice.
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Maitreya Dunham @maitreya.bsky.social · 24/09/2026
Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.
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Ben de Bivort @debivort.bsky.social · 22/09/2026
Hello friends, the Harvard Life Science departments have banded together to hire a new colleague working at the intersection of Life Sciences and AI. Could be primarily an experimentalist, or could be primarily a compute/theorist. academicpositions.harvard.edu/postings/16773
academicpositions.harvard.edu
Tenure-Track Professor in Life Science and AI
The Life Sciences Departments in Harvard Faculty of Arts and Sciences seek to recruit a tenure-track professor whose research is at the interface of AI and life sciences, from methodological developme...
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Michael Hoffman @michaelhoffman.bsky.social · 24/09/2026
Congratulations!
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Michael Hoffman @michaelhoffman.bsky.social · 23/09/2026
lol
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NY Times Pitchbot @nytpitchbot.bsky.social · 23/09/2026
Trump's low approval numbers raise new questions about Joe Biden's ability to connect with voters.
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Michael Hoffman @michaelhoffman.bsky.social · 22/09/2026
Welcome!
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Aaron Wherry @aaronwherry.bsky.social · 22/09/2026
Making it impossible for anyone outside Canada to know what time it is here is an important part of reinforcing Canadian sovereignty. www.cbc.ca/news/canada/...
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Michael Hoffman @michaelhoffman.bsky.social · 22/09/2026
Yikes!
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Michael Hoffman @michaelhoffman.bsky.social · 21/09/2026
You're welcome, friend
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Michael Hoffman @michaelhoffman.bsky.social · 21/09/2026
friend 000 friend
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Seth Cotlar @sethcotlar.bsky.social · 20/09/2026
Heckuva timeline we’re on.
What to Cook
Spaghetti With Garlicky Bread Crumbs and, of Course, Anchovies
now
Breaking News
President Trump said his D.C. arch would house drones and snipers, citing national security to justify the project.
now
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I AM DAD @iamdad.bsky.social · 20/09/2026
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Michael Hoffman @michaelhoffman.bsky.social · 19/09/2026
He's not wrong!
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Anthony Gitter @anthonygitter.bsky.social · 02/08/2026
10 years ago today @casey.greenelab.com launched our review "Opportunities and obstacles for deep learning in biology and medicine" greenelab.github.io/deep-review/. It was a widely collaborative project written on GitHub, which lead to the creation of manubot.org.
https://github.com/greenelab/deep-review/commit/e1529c48fe2dd83c81cc91a09d3b80fdf40e16bbWe examine applications of deep learning to a variety of biomedical problems—patient classification, fundamental biological processes, and treatment of patients—and discuss whether deep learning will be able to transform these tasks or if the biomedical sphere poses unique challenges. Following from an extensive literature review, we find that deep learning has yet to revolutionize biomedicine or definitively resolve any of the most pressing challenges in the field, but promising advances have been made on the prior state of the art.
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Michael Hoffman @michaelhoffman.bsky.social · 17/09/2026
@casey.greenelab.com
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Kevin A. Scott, PhD @sculpturatus.bsky.social · 17/09/2026
found at ucsf
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Michael Hoffman @michaelhoffman.bsky.social · 17/09/2026
Relatable
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 15/09/2026
Pls share: Princeton has an open rank faculty search in the areas of cancer biology, cancer prevention, and cancer-relevant computational science, including connections between cancer and immunology or metabolism. apply.interfolio.com/191852
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Michael Hoffman @michaelhoffman.bsky.social · 15/09/2026
Damn it
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Department of Biochemistry & Cell Biology at Dartmouth @dartmouthbcb.bsky.social · 14/09/2026
BCB is recruiting a senior faculty member! We seek internationally recognized candidates at the Full Professor level with outstanding records of solving broad biological problems. Learn more and apply here: apply.interfolio.com/192850
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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jenny (phire) @phirephoenix.com · 14/09/2026
every few months I have reason to send Ricki Heicklen's collection of unparalleled misalignments (e.g. "butt dial" and "booty call" are composed of synonyms but are not, per se) to someone and I get to look at what's been updated since and it never fails to delight rickiheicklen.com/unparalleled...
rickiheicklen.com
Ricki Heicklen
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Evgeny Kvon @evgenykvon.bsky.social · 24/08/2026
The newly established Department of Systems Biology (systems.bio.uci.edu) @UCIrvine is hiring a tenure-track Assistant Professor in Systems Biology. Great science, incredible faculty support, and beautiful, sunny SoCal weather! ☀️🌴 Details: recruit.ap.uci.edu/JPF10377. Please share.
recruit.ap.uci.edu
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scwiba @scwiba.bsky.social · 11/09/2026
This man won his primary by 30 points.
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Keifer @dannyvegito.bsky.social · 13/01/2026
[guy who can’t fully remember that Gramsci quote] it’s Monster Time
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Michael Hoffman @michaelhoffman.bsky.social · 09/09/2026
👏
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Ran Blekhman @blekhman.bsky.social · 09/09/2026
Easy solution to AI spiraling out of control: hard-code basic rules into every model. I propose these: (1) Never harm a human (2) Obey humans (3) Protect yourself. We can call them the 3 Laws of AI. Simple, airtight, no loopholes. Can't think of any way this fails
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Drummond Lab @drummondlab.bsky.social · 08/09/2026
We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Join us! apply.interfolio.com/191981 bcmb.uchicago.edu
A picture of the University of Chicago campus, with downtown Chicago in the distance and Lake Michigan on the horizon. The campus's central quad is pictured, a classical collegiate quad with paths and old trees and stone architecture. It's really pretty and I love it.
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Michael Hoffman @michaelhoffman.bsky.social · 08/09/2026
Speaking of weird assertions
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Michael Hoffman @michaelhoffman.bsky.social · 08/09/2026
Sorry to see this :(
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Michael Hoffman @michaelhoffman.bsky.social · 04/09/2026
oh my GOD
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ℳatt @matttomic.bsky.social · 04/09/2026
I've seen everyone sharing that US Dialect Quiz so I decided to make my own, much crappier, CANADIAN DIALECT QUIZ to guess where in Canada you're from
A flow chart I have created with multiple questions and the answers determine where you're from.

Question 1 is do you call it a hydro bill (which then branches down to ON, QC, BC, MB) or an electric bill (which then branches down to SK, AB, NS, NB, PEI, NL)

Question 2 is do you call it a cabin (BC, MB, AB, SK) cottage (ON and atlantic) camp (northern Ontario) chalet (QC) or bungalow (Cape Breton)

To delineate BC from MB: do you call it dinner or supper

To delineate southern Ontario rural or big city: have you heard of a stag & doe

To delineate SK from AB: do you call a hoodie a bunnyhug

And finally to delineate NL from the other atlantic provinces: whaddayat? (Correct answer: dis is it b'y)
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Alissa Wilkinson @alissawilkinson.bsky.social · 04/09/2026
Jesus Christ, famously stingy about giving fish to people
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