BMC Biology is calling for submissions to our Collection on Cell biology of virus-host interactions. The study of viral-host interactions lies at the heart of ...

Author summary Autophagy, like the Interferon (IFN) system, is considered part of the innate immune defenses activated upon viral infection. However, some viruses, such as measles (MeV) and respirator...

Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lower dement...

YouTube video by KeystoneSymposia

Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lower dement...

Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lower…

Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lower…

YouTube video by KeystoneSymposia

ID: 8551. Title: Postdoctoral Research Associate (Molecular Biology of HIV Infection). Application Deadline:

The innate immune system is known for its ability to recognize cytosolic DNA as evidence of infection, but detailed studies of this process have been mostly limited to mice and cell lines. To investig...

Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...

Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...

The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable to bind the actinmodulating kinas...

Brain-Drain in den USA: Mehr Forschende kommen nach Deutschland

The Helmholtz Institute for RNA-based Infection Researchopens a call for

Author summary Hepatitis E virus (HEV) is an important yet often underestimated pathogen. Depending on the genotype, HEV infections can progress to chronicity, but the underlying mechanisms remain poo...

In contrast to living organisms, viruses were long thought to lack protein synthesis machinery and instead depend on host factors to translate viral transcripts. Here, we discover that giant DNA virus...

Merold and Bekere et al. reveal that OAS2 exists as a zinc-mediated dimer in an autoinhibited state, preventing autoreactivity to short RNAs. Dimer-to-monomer transition, dsRNA binding to a non-canonical interface, and targeting to the Golgi by myristoylation are necessary for OAS2 activation and restriction of viruses that form double membrane vesicles.

Research project is combining central registry with local brain imaging data by means of artificial intelligence.

Herpesvirus proteins disrupt centromeres, triggering centromeric DNA amplification and local nuclear activation of the nucleic acid sensor cGAS. This reveals an immune surveillance mechanism in the nu...