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Veit Hornung

@v-hornung.bsky.social
861 followers 35 following 5 posts

(Innate) Immunologist at LMU Munich

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Iannacone Lab @iannaconelab.bsky.social · 18/10/2025
Join us for this exciting meeting! @embo.org Workshop "Pathogen Immunity and Signalling", 8-12 June, 2026, Leiden, The Netherlands meetings.embo.org/event/26-pat...
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Reposted by Veit Hornung
Ivan Zanoni @lozanzi.bsky.social · 19/10/2025
#WeekendRead! #ToSenseOrNotToSense! #MysterySolved! Berouti, Wagner, Carell, @v-hornung.bsky.social &co show @cp-cell.bsky.social that RNase T2 & PLDs generate #TLR7 & #TLR8 agonistic ligands only if RNA does not contains pseudouridines explaining avoidance of self RNA sensing!
sciencedirect.com
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
Recognition of exogenous RNA by Toll-like receptors (TLRs) is central to pathogen defense. Using two distinct binding pockets, TLR7 and TLR8 recognize…
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Reposted by Veit Hornung
Tobias Komar @t-komar.bsky.social · 09/08/2025
Excited to share the first paper of my PhD, published in the Journal of Biological Chemistry. Huge thanks to all authors, especially to co-first author Stefan Bauernfried, Alex Horswill‘s lab and @mannlab.bsky.social, and my supervisor @v-hornung.bsky.social. www.jbc.org/article/S002...
jbc.org
Inflammasome-independent IL-1β activation via staphopain A protease of Staphylococcus aureus
Interleukin-1β (IL-1β) is a pivotal mediator of innate immunity, essential for orchestrating the acute inflammatory response. While the canonical activation of IL-1β involves cleavage of its inactive ...
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Keystone Symposia @keystonesymposia.bsky.social · 16/09/2025
⏰ Deadline: Sept 17 (11:59pm MDT) Early-career scientists - submit an abstract or apply for a scholarship for #KSAutoImmune26: Autoimmunity & Autoinflammation 🧬 📅 Jan 19–22, 2026 | Breckenridge, CO 👉 keysym.us/KSAutoimmune26 youtu.be/nMsJANbMb-w #KSAutoImmune26 @v-hornung.bsky.social
youtu.be
Autoimmunity & Autoinflammation Meeting Promo
YouTube video by KeystoneSymposia
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Pavel Kielkowski @pavelkielkowski.bsky.social · 23/09/2025
The final version of our article about PLD3 AMPylation is now out shorturl.at/iTxWx. One protein, many proteoforms. Congratulations to Laura and thanks to @marleenberouti.bsky.social @v-hornung.bsky.social @jaelab.bsky.social @hellmichgroup.bsky.social
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Rebsamen Lab @UNIL @rebsamenlab.bsky.social · 28/01/2025
We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky
wp.unil.ch
Symposium immunobiology
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Journal of Experimental Medicine @jem.org · 24/01/2025
New: Sato, Miyake @UTokyo_News_en and colleagues report that the lack of RNase T2 activates TLR13, the sensor of bacterial 23S ribosomal RNAs, leading to the accumulation of tissue-protective Kupffer cells. buff.ly/4hw6kL0 Companion study by @v-hornung.bsky.social buff.ly/4jG49Gy
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Waggoner Lab @labwaggoner.bsky.social · 24/01/2025
RNase T2 plays an important role in limiting self-RNA recognition by preventing erroneous activation of TLR13 @jem.org @v-hornung.bsky.social doi.org/10.1084/jem.... doi.org/10.1084/jem....
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Sorek Lab @soreklab.bsky.social · 23/01/2025
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10 www.cell.com/cell/abstrac...
cell.com
Structure-guided discovery of viral proteins that inhibit host immunity
Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify those that bind and antagonize host immune proteins. Detected proteins are shown to inhibit no...
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Louis-Jeantet Foundation @louisjeantetfdn.bsky.social · 21/01/2025
VEIT HORNUNG @v-hornung.bsky.social @genecenter-lmu.bsky.social is awarded the 2025 Collen-Jeantet Prize for Translational Medicine for his important contributions to our understanding of how foreign nucleic acids and other non-self signals trigger the innate immune system.
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Pavel Kielkowski @pavelkielkowski.bsky.social · 16/01/2025
Proteoforms matter! We show how AMPylation impacts PLD3 proteolytic processing and catalytic activity. Congratulations to Laura Hoffmann and thanks to all collaborators @jaelab.bsky.social, @v-hornung.bsky.social, @hellmichgroup.bsky.social and Wei Xiang lab! www.biorxiv.org/content/10.1...
biorxiv.org
AMPylation regulates PLD3 processing
The 5’-3’ exonuclease phospholipase D3 (PLD3) is a single-pass transmembrane protein undergoing sequential post-translational modifications (PTM) by N -glycosylation, AMPylation and proteolytic cleava...
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Aude Bernheim @audeber.bsky.social · 09/12/2024
Registration now open for the EMBO Workshop: Immune System of Bacteria !!!! www.sisb2025.conferences-pasteur.org/home Joins us in Institut Pasteur, Paris, April 8-10th.
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Brian Ferguson @viropractor.bsky.social · 29/11/2024
We are recruiting an associate or full Professor of Infection and/or Immunity to the school biological sciences in Cambridge. Full details here: www.jobs.cam.ac.uk/job/49381/ #immunology #virology
jobs.cam.ac.uk
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
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Gene Center Munich @LMU Munich @genecenter-lmu.bsky.social · 19/11/2024
Don't miss this opportunity for your next career step:
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Veit Hornung @v-hornung.bsky.social · 19/11/2024
📢 Postdoc opening! 📢 @soreklab.bsky.social and we are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research in two dynamic fields. Interested? Let’s connect! 👇 www.genzentrum.uni-muenchen.de/career/postd...
genzentrum.uni-muenchen.de
Postdoctoral Position (f/m/x) in Immunology / Biochemistry / Computational Biology - Gene Center Munich - LMU Munich
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