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Madison Sneve

@madisonsneve.bsky.social
229 followers 478 following 0 posts

Graduate student @ Harvard neuro, insect enthusiast

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Reposted by Madison Sneve
John Tuthill @tuthill.bsky.social · 01/10/2026
two new preprints from Wangchu Xiang (@darbly.bsky.social, Ginty labs) about connectomic reconstruction from electron microscopy of somatosensory afferents and projection neurons in the dorsal horn of the mouse spinal cord www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...
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Jolyon Troscianko @jtroscianko.bsky.social · 30/09/2026
🦋 Butterfly wing patterns create motion illusions that protect them from predators! Our new study (8 years in the making) is out in Nature today doi.org/10.1038/s415... @grahancock.bsky.social @esbriolat.bsky.social @scienceanna.bsky.social @lauraakelley.bsky.social @uniexecec.bsky.social
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Ivy Chan @ivychanchiwai.bsky.social · 25/09/2026
Our paper on odour categorization in the Drosophila mushroom body is now out in Cell Reports! 🎉 We found that αβ and α′β′ Kenyon cells—but not γ KCs—distinguish food-related from non-food odours at the population level. Very happy to see this work published! 🪰🧠 doi.org/10.1016/j.ce...
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Rafael Pinilla-Redondo (Rafa) @rafomics.bsky.social · 16/07/2026
1/10 🚨Preprint! One RING to rule them all (phages)👑💍⚔️ Bacteria build giant DNA-scaffolded RNase rings (larger than the ribosome!) to shut down viral infection🧬🧵👇 biorxiv.org/content/10.6...
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Dan Goodman @neural-reckoning.org · 16/07/2026
New preprint (well, very updated). 🤖🧠🧪 We find that an abstract model of neuromodulation lets spiking neural networks perform much better, particularly in challenging noisy environments, using less energy. Relevant to #neuroscience and #neuromorphic computing. 🧵👇 www.biorxiv.org/content/10.1...
biorxiv.org
Neuromodulation enhances the capability and efficiency of spiking neural networks
Spiking neurons underlie the brain’s extreme energy efficiency, and therefore have great potential in neuromorphic computing, although realising this efficiency in practice has proven challenging. We ...
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Kevin Terretaz @kwolbachia.bsky.social · 17/07/2026
New favorite way to color code microscopy data: this is a real 3D confocal image of an unidentified larvae stained for actin (muscles fibers here). Looks like a watercolor painting! #microscopy #ImageJ #FluorescenceFriday #microscopyMonday
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stefanofusi.bsky.social @stefanofusi.bsky.social · 15/07/2026
From a great collaboration with @lorenzoposani.com, @shuqiw.bsky.social, Samuel Muscinelli, Liam Paninski, now in Nature: www.nature.com/articles/s41...
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
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Aran Nayebi @anayebi.bsky.social · 13/07/2026
1/6 Why have deep neural networks aligned so strongly with brains for the past 15 years? What explains it? @dyamins.bsky.social & I make progress on this question in our new paper👇 In a nutshell, we *prove* that for sufficiently hard tasks, the choice of alignment metric does *not* matter.
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Louis Pezon @lpezon.bsky.social · 30/06/2026
Both brains and RNNs can re-use components of computation across similar tasks or contexts. But what exactly are those “shared components”? How can they be used to solve several tasks? We address these questions in a new preprint with @avm.bsky.social! Link: www.biorxiv.org/content/10.6...
biorxiv.org
Interpretable compositional computation with recurrent neural networks
Flexible cognition utilizes reusable components to enable rapid adaptation of behavior to different contexts or tasks. Analysis of artificial neural networks trained on multiple tasks suggested that t...
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Nancy Moran @nancy-moran.bsky.social · 02/07/2026
A step forward in discovering Buchnera's key to the aphid's heart, published today! Thanks to Jerry Maeda and other authors--a great team -- and to the helpful reviewers #SymbioSky doi: doi.org/10.1038/s415...
doi.org
A secreted endosymbiont protein essential for colonizing host cells - Nature
SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera transmission.
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Ian Dworkin @idworkin.bsky.social · 29/06/2026
I am excited to tell you about our new study led by Tyler Audet and in collaboration with Stefan Lüpold's group. Below you see two species. On the right is Drosophila melanogaster. On the left, Drosophila prolongata. Notice the highly exaggerated legs of the males in D.p! doi.org/10.1093/evol...
Two panel image of Drosophila prolongata and Drosophila melanogaster. In the top panel is a female of Drosophila prolongata on the left and a female of Drosophila melanogaster on the right. It shows that D. prolongata females are somewhat larger than melanogaster, and have spotted wings. Importantly the legs are proportional in each species.

In the bottom panel are males. On the left is a Drosophila prolongata male which is larger than all the other individuals, and has highly exaggerated legs in terms of width and length, and also has black stripes. In contrast male Drosophila melanogaster are much smaller than all the others, with normally proportioned legs.
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eLife @elife.bsky.social · 19/06/2026
A fundamental study of individual variation and contribution of learning to behavioural individuality. Conclusions are supported by compelling, rigorous analysis across a number of experiments in thousands of individuals across genotypes and conditions.
buff.ly
Learning is a fundamental source of individuality
Altmetric provides a collated score for online attention across various platforms and media.See more details
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paveltomancak.bsky.social @paveltomancak.bsky.social · 18/06/2026
Big paper from @hejnol.bsky.social lab. Title says it all. Congrats, Stanislav Kremnyov and the team. www.nature.com/articles/s41...
nature.com
A blastoporal organizer in a ctenophore - Nature
Experiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transit...
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Gizem Özdil @gzmozd.bsky.social · 18/06/2026
🍎 Next time you see a fly cleaning itself on your fruit salad, you might think about it differently! ⬇️ Read this wonderful piece by the Kempner team on our work on fly grooming, including a short interview with me about the project. Link to the paper: www.nature.com/articles/s41...
nature.com
Centralized brain networks controlling antennal grooming coordination - Nature Communications
The neural basis of grooming behavior remains incompletely understood. Here, the authors combine behavior, biomechanical simulations, connectome analysis, and neural network modeling to uncover centra...
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Science Magazine @science.org · 14/06/2026
A new Science study shows that bumble bees can position a ball underneath a fake “flower” to reach a reward, suggesting they can exhibit spontaneous problem-solving and challenging the notion that such advanced cognitive abilities are exclusive to large-brained vertebrates. scim.ag/4vs08dC
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Wei-Chung Allen Lee @darbly.bsky.social · 12/06/2026
A great privilege of science is working with remarkable people. A nice piece highlighting @mindyisminsu.bsky.social. Her grit, esp through the pandemic, was foundational to the #BANC project. hms.harvard.edu/news/making-...
hms.harvard.edu
Making Connections, in the Brain and in Science
PhD student Minsu Kim gained confidence, experience in the lab of neurobiologist Wei-Chung Allen Lee
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Flavio Martinelli @flavioh.bsky.social · 10/06/2026
NEW PAPER. Why do larger networks train better? "Because they contain more candidate *sub*networks that can learn the task" → lottery tickets This popular explanation uses an appealing but misleading metaphor🧵 We propose an intuitive alternative grounded in theory: escape dimensions
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Ajay Narendra @pipilika.bsky.social · 02/06/2026
New article: We studied how volumes of different brain regions vary between workers, males & alate females in 2 species of Australian ants. First paper from Saroja Ellendula's PhD thesis! Article is available here: bit.ly/4fVwCIN @neuroethology.org @austentsoc.bsky.social @animbehav.bsky.social
Pictures of workers, males and alate females of two Australian ant species3D reconstruction of brains of workers, males and alate females of two Australian ant species.
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Reese Richardson @reeserichardson.bsky.social · 28/05/2026
TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...
reeserichardson.blog
How much of Thermo Fisher’s antibody data has been manipulated?
We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog
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Mike Keesey @tmkeesey.bsky.social · 25/05/2026
We now have 12,463 silhouettes on PhyloPic! Cant believe it took this long to get a Sacabambaspis. #sciart www.phylopic.org/images/a6428...
phylopic.org
Sacabambaspis janvieri by Petr Menshikov (original illustration), T. Michael Keesey (vectorization) (CC BY 4.0) - PhyloPic
A free silhouette image of Sacabambaspis janvieri Gagnier & al. 1986 by Petr Menshikov (original illustration), T. Michael Keesey (vectorization) (License: Attribution 4.0 International).
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Brad Hulse @bradkhulse.bsky.social · 21/05/2026
Story time friends... Ring attractor networks rely on fine-tuned symmetric connectivity. The fly head direction network has ring attractor dynamics but heterogeneous connectivity. How is this possible? 1/🧵 Link: www.biorxiv.org/content/10.6...
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Jennifer O’Chan @chanjenerational.bsky.social · 21/05/2026
Thrilled to share my main postdoctoral work out @nature.com ! This project tackles a fundamental question: how do pregnancy and postpartum experiences promote lifelong changes to the brain? www.nature.com/articles/s41...
nature.com
Dopamine drives persistent remodelling of the maternal brain - Nature
Brain-wide transcriptomic profiling in mice reveals that reproductive experience remodels the maternal brain by altering dopamine dynamics in the dorsal hippocampal formation, causing dopamine-depende...
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Rui Xu @rui-xu.bsky.social · 20/05/2026
New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n
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eric lai @lucksmith.bsky.social · 18/05/2026
this review topic is so metal. and also very @currentbiology.bsky.social! 🤘 one thing i didn't appreciate is that one advantage of "ballistic tongues" is that they operate over a broader temperature range than muscle shortening action. www.cell.com/current-biol...
cell.com
Ballistic tongues
Zeng and Deban provide an overview of ballistic tongues in three vertebrates, highlighting similarities and differences in launch and retraction mechanisms, ecological advantages, evolutionary history...
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Annika Barber @annikabarber.bsky.social · 19/05/2026
All my friends are SO COOL! Monika and her lab assure us you can build this cool scope in <4 hours and use it to explore not just her favorite organism 🪱, but also mine 🪰, and also tardigrades! Wanna calcium-image your lil wiggly guys while they do their thing? Now you can! 🧪 doi.org/10.1038/s414...
doi.org
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior - Nature Communications
Researchers present a low-cost, modular fluorescence microscope built entirely from commercial parts for research and education. Demonstrations include muscle dynamics in Drosophila larvae, stride ana...
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Drew Schreiner @schreinerdrew.bsky.social · 13/05/2026
Where, exactly, does learning happen in the brain? Out today in @nature.com, we identify a synaptic locus of birdsong learning and show that the circuit can be tuned to make birds learn faster - but at a cost. Read on👇 #neuroskyence 🧪 #prattle 💬 #bioacoustics Shareable link: rdcu.be/fiyrS
nature.com
A synaptic locus of song learning - Nature
Combining a computational framework and optogenetic and&nbsp;chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...
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MultiplEye Lab @multipleye-lab.bsky.social · 13/05/2026
📢 New pre-print alert! Most spiders have eight eyes, but not all - PhD researcher Antonio Galán Sánchez and Dr Andres Rivera Quiroz @naturalis.bsky.social led an exciting new analysis of the evolution of eye number and losses in spiders on a truly incredible scale! www.biorxiv.org/content/10.6...
biorxiv.org
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Reece Keller @reecedkeller.bsky.social · 05/06/2025
1/ I'm excited to share recent results from my first collaboration with the amazing @anayebi.bsky.social and @leokoz8.bsky.social ! We show how autonomous behavior and whole-brain dynamics emerge in embodied agents with intrinsic motivation driven by world models.
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Daniel Anthes @anthesdaniel.bsky.social · 11/05/2026
Excited about our new preprint: “The illusory simplicity of the feedforward pass: evidence for the dynamical nature of stimulus encoding along the primate ventral stream” arxiv.org/abs/2604.12825 Work with Sushrut Thorat, Anna Mitola, Paolo Papale, Peter König & Tim Kietzmann 🧵 thread below
arxiv.org
The illusory simplicity of the feedforward pass: evidence for the dynamical nature of stimulus encoding along the primate ventral stream
In studying primate vision, a large body of work focuses on the first feedforward sweep. During this initial time window, information is thought to pass through ventral stream regions in a stage-like ...
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Amelia Eisch 🧪🧠👩‍🔬 🐁 @eisch.bsky.social · 05/05/2026
1/ New preprint! 🧪With @talmo.bsky.social and team, we used deep learning on archival NASA video of mice on the ISS. Turns out mice in microgravity become tiny acrobats: huddling to sleep, doing backflips, even briefly generating their own ~1g. #SpaceBiology #OpenScience #NASA #SLEAP
biorxiv.org
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Aurel A. Lazar @aalazar.bsky.social · 05/05/2026
Flies vision is tightly intertwined with action, using motion itself to sharpen perception and speed up neural processing. Understanding how biology achieves predictive, low‑delay sensing could inspire new approaches in artificial vision and neuromorphic engineering. www.nature.com/articles/s41...
nature.com
Synaptic high-frequency jumping synchronises vision to high-speed behaviour - Nature Communications
How insects maintain precise vision during rapid motion remains unclear. Here, the authors show that motion-driven photoreceptor dynamics and synaptic high-frequency jumping enable hyperacute, minimal...
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Nicole Rust @nicolecrust.bsky.social · 27/04/2026
Yes!!!! Beautiful essay, @tonyzador.bsky.social.
So where does this leave us? The compression step, collapsing a sprawling dataset into something portable and teachable, remains (for now, at least) a human activity. AI models can predict; they have not yet learned to explain. But the Vafa result suggests that the drive toward understanding isn’t just a scientist’s vanity. Even in the age of large AI models, it may remain our most important job.
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ZooKeys @zookeys.pensoft.net · 14/04/2026
🌊 We are thrilled that our latest special issue on Clarion-Clipperton Zone amphipods has been featured in: @discovermag.bsky.social: www.discovermagazine.com/24-newly-dis... @mongabay.com: news.mongabay.com/2026/04/24-n... Oceanographic Magazine: oceanographicmagazine.com/news/new-bra...
discovermagazine.com
24 Newly Discovered Species Reveal a New Branch of Life Hidden in the Deep Sea
Learn how researchers discovered a new superfamily living at the bottom of the Pacific Ocean.
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Current Biology @currentbiology.bsky.social · 13/04/2026
On the cover of our current issue: the 'cool' snow fly❄️❄️❄️ whose genome reveals several fascinating cold adaptations. www.cell.com/current-biol...
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The Transmitter @thetransmitter.bsky.social · 08/04/2026
Researchers reveal the neural basis of evolving new capabilities by investigating behavioral and morphological differences between deer mouse subspecies. #neuroskyence By @siddhantpusdekar.bsky.social www.thetransmitter.org/evolution/ar...
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Emilie Macé @mace-lab.bsky.social · 08/04/2026
1/8. New preprint! ✨ How spontaneous is spontaneous behavior? 🧠🐭 We found that whole-brain fUSi signals predicted spontaneous behavioral transitions seconds in advance. Inhibiting one node of this transition-prone state, the medial septum, facilitated switching! www.biorxiv.org/content/10.6...
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c0nc0rdance @c0nc0rdance.bsky.social · 08/04/2026
Wayne Maddison (waynemaddison.bsky.social), professor emeritus at UBC, captured this video of a nearly transparent jumping spider (tribe Amycini) from Canandé Reserve, Ecuador. Look closely & you'll see the principal eyes moving as it scans the area visually. Let's talk about spider-vision! 🕷️🧪
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Ctenophores Rock! @ctenophoresrock.bsky.social · 07/04/2026
Happy #CtenophoreCtuesday! Enjoy this bloody-belly comb jelly (Lampocteis cruentiventer) for your moment of zen 🔊🪼 The color red is nearly invisible in deep-sea allowing these jellies to hide from potential predators. Credit video to @mbarinews.bsky.social. #sciart #science #scicomm #ctenophore
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Katrin Vogt @katrinvogt.bsky.social · 31/03/2026
Check out our new preprint and learn about the smart foraging behavior of fly larvae! www.biorxiv.org/content/10.6...
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Venki Murthy @neurovenki.bsky.social · 24/03/2026
Evolution seems to have repeatedly converged on a similar architecture in the early olfactory system of many animals. We offer an efficient-coding framework to understand this. Out in @pnas.org now! Led by @jzv.bsky.social, driven by Juan Carlos, + help from Farhad. www.pnas.org/doi/10.1073/...
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Marcus Stensmyr @marcusstensmyr.bsky.social · 24/03/2026
Genome of the Abominable Snowfly uncovers the mysteries of cold tolerance in a winter active insect! New cool (literally) paper in @currentbiology.bsky.social from Marco Gallio, @matthewcapek.bsky.social, @tuthill.bsky.social, myself, and fine colleagues! ⛄ 🦟 authors.elsevier.com/sd/article/S...
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Harvard_MCB @harvardmcb.bsky.social · 24/03/2026
Why Evolution Keeps Returning to the Same Solution for Smell 🧠 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @neurovenki.bsky.social @kempnerinstitute.bsky.social @pnas.org @harvardbrainsci.bsky.social @jzv.bsky.social @rachellegaudet.bsky.social @naoshigeuchida.bsky.social
mcb.harvard.edu
Why Evolution Keeps Returning to the Same Solution for Smell - Harvard University - Department of Molecular & Cellular Biology
Why do animals as different as insects and mammals process smells in nearly the same way? A new theoretical study published in PNAS takes on this question by […]
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Datta Lab @dattalab.bsky.social · 25/03/2026
Have you ever wondered why mice do what they do when they are free to do whatever they want? Check out our latest (and this slightly delayed thread about our recent paper, led by Caleb Weinreb and friends...) www.cell.com/neuron/fullt...
cell.com
Spontaneous behavior is a succession of self-directed tasks
Weinreb et al. reveal a hierarchy of timescales in mouse behavior, including low-level syllables and high-level behavioral states. States and syllables are encoded in different brain areas. Prefrontal...
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John Tuthill @tuthill.bsky.social · 24/03/2026
🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...
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Claudia Clopath Lab @clopathlab.bsky.social · 23/03/2026
Check out our new paper on computational modelling of epigenetic plasticity! With the lab of @graeffjohannes.bsky.social academic.oup.com/brain/advanc...
academic.oup.com
A computational framework for epigenetic plasticity in memory
Delamare et al. present a computational model of memory formation inspired by recent experimental data, in which individual memories are encoded not only i
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Hannah Haberkern @hannah-haberkern.bsky.social · 19/03/2026
How does an animal choose between exploring for a better food source and taking advantage of a known one? Our recent work in Current Biology demonstrates how recent feeding and metabolic state dynamically influence fly local search. bit.ly/3PfrIv3 #Science #Neurosky #Foraging #Drosophila
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Alex Williams @itsneuronal.bsky.social · 19/03/2026
Cosyne invited me to give a long tutorial (4 hours!) on methods to quantify differences high-d neural recordings across animals, brain regions, deep neural nets, etc. The recording is up on youtube. I hope it inspires more research on this fundamental topic! www.youtube.com/watch?v=n44x...
youtube.com
Cosyne 2026 - Cosyne Tutorial: Comparative Analysis of Neural Population Codes
YouTube video by Cosyne Talks
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Thibaut Brunet @thibautbrunet.bsky.social · 20/03/2026
Expansion microscopy of a loricate choanoflagellate, generated by Mylan Ansel in our lab 🤩 (yes, the lorica expands. No, we don't understand how either)
Credit: Mylan Ansel
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samuel mehr @mehr.nz · 19/03/2026
out now in Science: @loganjames.bsky.social collected pairs of sounds in 16 species where we *know* which sound is more attractive (to that species) he played them to ppl on themusiclab.org, asking, in each pair, which was nicer. humans agreed w other animals doi.org/10.1126/science.aea1202
cOMPaRatiVe cOGNitiONHumans share acousticpreferences with other animalsLogan S. James1,2,3,4* Sarah C. Woolley 1,2, Jon T. Sakata1,2,Courtney B. Hilton5,6, Michael J. Ryan3,4, Samuel A. Mehr5,7,8Many animals produce courtship sounds, and receivers prefersome sounds over others. Shared ancestry and convergentevolution may generate similarities in preference across speciesand underlie Darwin’s conjecture that some animals “havenearly the same taste for the beautiful as we have.” In this study,we show that humans share acoustic preferences with a rangeof animals, that the strength of human preferences correlateswith that in other animals, and that humans respond fasterwhen in agreement with animals. Furthermore, we foundgreatest agreement in preference for adorned, ancestral, andlower-frequency sounds. humans’ music listening experiencewas associated with preferences. These results are consistentwith theories arguing that biases in processing sculpt acousticpreferences, and they confirm Darwin’s century-old hunchabout the conservation of aesthetics in nature
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Roy Eyono @royeyono.bsky.social · 19/03/2026
How do neural circuits in the brain implement normalization? 🧠 In our new paper, we show that just normalizing sensory input isn't enough. Crucially, we must also normalize the error signals! 🧵👇 Paper: arxiv.org/abs/2603.17676
arxiv.org
Inhibitory normalization of error signals improves learning in neural circuits
Normalization is a critical operation in neural circuits. In the brain, there is evidence that normalization is implemented via inhibitory interneurons and allows neural populations to adjust to chang...
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