Voltage-gated ion channels do not distribute evenly in the plasma membrane of a neuron; they localize to distinct domains where they govern the exc...

Neural sequences, characterized by neurons or groups of neurons that fire one after the other, have been observed in multiple brain regions, across species, and are known to underlie a diversity of br...

Neuronal circuits in the olfactory bulb (OB) perform computations fundamental to pattern classification including a decorrelation and normalization of odor-evoked activity. These computations are medi...

Brains rely on internal models of the world to interpret sensory input and to simulate the future. In the mammalian hippocampal-entorhinal network, environments are represented by cognitive maps that ...

Intelligent behavior requires experience-dependent internal representations of relevant information. We examined representational learning in telencephalic area pDp of adult zebrafish, the homolog of ...

The Drosophila whole male central nervous system connectome enables end-to-end analysis of sensorimotor circuits. Comparison with existing female datasets shows that brain-wide wiring differences betw...

The authors use recurrent neural networks to predict how structured prior experience shapes neural dynamics as mice learn flexible timing strategies during complex context-dependent behavior.

Using a virtual reality system, experiments in Drosophila show that flies use memory mechanisms to navigate along the boundary of an odour plume and track the source of a smell.

All physical interactions between an organism and its environment occur within the space immediately adjacent to and surrounding its body, its peripersonal space (PPS). This space has been extensively...

Difficult decisions require gathering evidence over extended periods, placing demands on working memory. Yet, how working memory limitations affect decision-making remains largely unknown. We trained ...

Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...

GNB1 encephalopathy (GNB1-E) is a rare neurodevelopmental disorder associated with motor dysfunction, epilepsy and learning disability caused by mutations in the gene encoding the G protein subunit Gβ...

Variability is a prominent feature of animal behavior across species. Despite highly controlled experimental conditions, the same individual often responds differently to repeated identical stimulatio...

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Using in vivo whole-cell recordings during goal-directed navigation, Bhatia, Adel, and Grienberger identify plateaus as a prominent feature of subiculum activity. These events preferentially occur nea...

The neuromodulator octopamine, the insect counterpart to norepinephrine, helps flies get their bearings in an unfamiliar environment.

Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where...

Research Software Engineer

Research Technician position available in the Grienberger lab at Brandeis University. We are a new neuroscience group studying the cellular basis of learning and memory in the mammalian brain. This is...

For 20 years the beautiful structure in the grid cell code has presented an attractive puzzle: what computation do these representations subserve, and why does it manifest so curiously in neurons. The...