iiinova — where your digital self keeps evolving

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bioRxiv Genomics @biorxiv-genomic.bsky.social · 23/09/2026

An atlas of eukaryotic centromere architecture reveals recurrent evolutionary dynamics www.biorxiv.org/content/10.64898/20…

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Reese Richardson @reeserichardson.bsky.social · 05/06/2026

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · 01/04/2026

New preprint! We identified many components that localize to the structure involved in "eating" in a marine organism. #ProtistOnSky #diplonemid www.biorxiv.org/content/10.6...

biorxiv.org

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Clinton Lau @ckylau.bsky.social · 30/03/2026

Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

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Takashi Akera Lab @takashiakeralab.bsky.social · 22/03/2026

We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️

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Nilsson lab @nilssonlab.bsky.social · 06/03/2026

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...

nature.com

A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology

Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

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Eelco Tromer @eelcotromer.bsky.social · 26/02/2026

We're on a roll here. Check out this cool paper by @scienceleah.bsky.social et al. on not one, but two types of sperm (!) in the silk worm Bombyx mori. Happy to have contributed. #meiosis4ever

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Kops Lab @kopslab.bsky.social · 23/02/2026

As a cell biology lab, we acknowledge the decades-long impressive efforts to uncover evolutionary relationships using advanced phylogenomics methods. These approaches undergo continuous improvements that lead to adjustments of data interpretation, as is the case in every scientific field. (1/3)

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Andrew Roger @andrewjroger.bsky.social · 23/02/2026

Before he passed away in 2021, Tom Cavalier-Smith had drafted parts of his autobiography. It's now 'published' because Gáspár Jékely put a lot of effort in! Please enjoy and share: doi.org/10.5281/zeno...

doi.org

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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 16/02/2026

Hamer + Spijker. Tijd voor verandering van de PhD stelsel op Nederlandse Universiteiten. Lees dit opiniestuk van @erikvansebille.bsky.social in het Digitaal Universiteitsblad van @utrechtuniversity.bsky.social

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Eelco Tromer @eelcotromer.bsky.social · 18/02/2026

Perpetually in awe of the astonishing creative capacity of retrotransposons in eukaryotic cell biology — makes you wonder what remarkable, still-hidden origin stories centromeres across the tree of life carry.

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 17/02/2026

A 🆕 #Ichthyosporea story Led by@margaridaaraujo.bsky.social, in Co. @gautamdey.bsky.social & @hiralshah.bsky.social+🔥team across @embl.org & @sciencesunige.bsky.social We finally have a look at what #microtubules are doing during #cellularization in #Sphaeroforma ▶️ tinyurl.com/MTSARC #ProtistsOnSky

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Max Raas @maxraas.bsky.social · 13/02/2026

Recently, a Hypothesis was posed in @jcellsci.bsky.social in which the root of eukaryotes was placed between kinetoplastids and all other eukaryotes. From this, it was implied that LECA did not have a kinetochore. We argue this is highly unlikely. A 🧵(1/12) Read our reply here: tinyurl.com/n87myhpr

tinyurl.com

The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025

Summary:Akiyoshi, 2025 presented a hypothesis with implications for the early evolution of eukaryotes and eukaryotic cell division machinery. In this Correspondence, the authors conclude that this hyp...

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bioRxivpreprint @biorxivpreprint.bsky.social · 20/01/2026

Direct binding of chromosome axis and cohesin complexes underlies meiotic chromosome architecture in fungi and plants www.biorxiv.org/content/10.64898/20…

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 26/12/2025

Another #notTHECover unfortunately. But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab. Read here: www.cell.com/cell/fulltex...

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Eelco Tromer @eelcotromer.bsky.social · 22/12/2025

Some light reading for the holidays :). Let us know what you think.

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Max Fürst @maxfus.bsky.social · 16/12/2025

New preprint🚨 Imagine (re)designing a protein via inverse folding. AF2 predicts the designed sequence to a structure with pLDDT 94 & you get 1.8 Å RMSD to the input. Perfect design? What if I told u that the structure has 4 solvent-exposed Trp and 3 Pro where a Gly should be? Why to be wary🧵👇

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Eelco Tromer @eelcotromer.bsky.social · 10/12/2025

#EvoChromo ciliate kinetochores @maxraas.bsky.social @kopslab.bsky.social . Previous work w\ @jvhooff.bsky.social : tinyurl.com/y5h4ehnt showed a lack of Tetrahymena kinetochore complexity. Replacement, simplification or missed homologies? All of the above? - check out our pre-print tiny.cc/hp8w001

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Max Raas @maxraas.bsky.social · 01/12/2025

Our story on the kinetochore composition of the ciliate Tetrahymena thermophila is out now on bioRxiv! We find surprisingly many orthologs of conventional kinetochore components, but also components that have very different evolutionary origins. A 🧵 (1/11) Check it out here: tinyurl.com/4ectm9x4

tinyurl.com

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Jana Helsen @helsenjana.bsky.social · 26/11/2025

How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉 doi.org/10.1038/s41586-025-09779-1

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Ryuji Yanase @ryanase.bsky.social · 24/11/2025

Our new preprint describes Plasmodium NEK4 as a key regulator coupling meiotic initiation and morphogenesis—a critical step for malaria transmission. This involves MTOC-driven nuclear movement strikingly analogous to "horsetail" movement in fission yeast. www.biorxiv.org/content/10.1...

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Eelco Tromer @eelcotromer.bsky.social · 31/08/2025

New work on ARK1 (AURKB?) in Plasmodium (malaria parasite) with @ritatewari.bsky.social and Pushkar Sharma. CPC in Plasmodium is (ofcourse..) different compared to conventional models: two INCENPs, no borealin/survivin - mainly at spindle microtubules/MTOCs. Special thanks to @ryanase.bsky.social!

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Ryuji Yanase @ryanase.bsky.social · 28/08/2025

Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". Many thanks to our collaborators. @ritatewari.bsky.social @eelcotromer.bsky.social @davidguttery.bsky.social www.biorxiv.org/content/10.1...

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Franzi Böwer @flipping-meiosis.bsky.social · 03/08/2025

Happy to share the first story from my postdoc in @schnittger-lab.bsky.social We studied TITAN9, a Csm1-like protein in Arabidopsis. Even though I now work with soil, chromosome segregation and meiosis still have a special place in my heart. #meiosis4eva #meiosis #chromosomesegregation

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Leah Rosin @scienceleah.bsky.social · 04/08/2025

So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms! www.biorxiv.org/content/10.1...

biorxiv.org

Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori

The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility and offspring health. However, Lepidopteran (moths and butterflies) males pr...

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Chris Morgan @morganlab.bsky.social · 21/07/2025

Postdoc position currently available in our group studying meiosis in arabidopsis and wheat: www.jic.ac.uk/vacancies/po...

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 17/07/2025

We are growing! A new @zeiss-microscopy.bsky.social widefield tailored for ExM- supported by @moorefound.bsky.social is settling! Another one is on its way at @gautamdey.bsky.social Lab ! These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !

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Eelco Tromer @eelcotromer.bsky.social · 23/06/2025

Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!

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Carlos Santana Molina @santanamolina.bsky.social · 03/03/2025

Asgardarchaea & Alphaproteobacteria: key players for the assembly eukaryotic central carbon metabolism! Our new study reveals their gene contributions to glycolysis & TCA cycle, supporting synthrophic scenarios of eukaryogenesis. rdcu.be/eb0aK

rdcu.be

Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes

Nature Ecology & Evolution - Analysis of the eukaryotic gene repertoires mediating central carbon metabolism identifies ancestral contributions from Alphaproteobacteria, Asgardarchaeota and...

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Jolien van Hooff @jvhooff.bsky.social · 05/03/2025

Exciting news! I'm looking for a computational biologist to join my lab at Wageningen University & Research! It's a 3-year postdoc position on Holomycota genome architecture and evolution. Spread the word! www.wur.nl/en/vacancy/p...

wur.nl

Postdoc Comparative genomics and genome architecture in early-diverging fungi and their protist relatives (3-year position)

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🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 08/12/2024

Have questions about #bioinformatics, #genomics, #evolution or stuck on a project? 🧬💻 I want to help! Happy to discuss data, figures, writing, academia/industry or chatting just for kicks—no strings attached Drop questions below, DM, or schedule a meeting Science together is better than alone 🙌

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · 05/01/2024

A new preprint from our group in collaboration with @jvhooff.bsky.social and @eelcotromer.bsky.social. We discovered that trypanosomes have (a zombie of) Bub1-Bub3 despite the fact that tryps do not have a canonical spindle checkpoint! This is a team work involving Dan, WillC, Midori and Patryk

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