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@bilderlab.bsky.social
1.9K followers 361 following 60 posts

Epithelial biology: polarizing proteins, elongating eggs, and cold-blooded cancer

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@bilderlab @bilderlab.bsky.social · 24/09/2026
"...given to the most striking image that clearly conveys a point of important biological information in Drosophila research…Because the Award is tied closely to science as well as aesthetics, only images that have been published in a primary research journal... are eligible." drosophila-images.org
drosophila-images.org
Drosophila Image Award |
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@bilderlab @bilderlab.bsky.social · 24/09/2026
This incident @nikonsmallworld brings to mind rules we set for the Drosophila Image Award in 2004. We didn't want to reward pretty pictures generated for their own sake, but celebrate the amazing images that emerge from everyday science, where beauty and discovery are inseparable. 1/2
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@bilderlab @bilderlab.bsky.social · 17/08/2026
Now out in Annu Rev Cancer Biol: "Beyond Mice and Men." We think of cancer as a disease of humans, as well as pets 🐈‍⬛ 🐕 & lab mice. But cancer is found across the animal tree of life, including clams and fruit flies. Comparative oncology has a lot to teach us. 🧵 www.annualreviews.org/content/jour...
annualreviews.org
Beyond Mice and Men: Alternative Vertebrate and Invertebrate Models in Cancer Biology
While cancer looms large in the public and scientific minds, this can result in a quite narrow view of its range and manifestations. The centering of human clinical investigations and the popularity o...
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Katy Ong @ongkaty.bsky.social · 01/12/2025
I've had a bit of a hiatus due to faculty job apps, but the Etsy shop is open again and ready for your holiday orders! All proceeds go to @flybase.bsky.social , and I just sent the August/September revenue donation. So grab some #drosophila stocking stuffers =>
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Katy Ong @ongkaty.bsky.social · 24/10/2025
@bilderlab.bsky.social Karaoke night. Please clap for my charcuterie board.
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@bilderlab @bilderlab.bsky.social · 18/10/2025
FWIW we also find that flies show coagulopathy, another big cause of death of cancer patients pubmed.ncbi.nlm.nih.gov/37354901/
pubmed.ncbi.nlm.nih.gov
Systemic coagulopathy promotes host lethality in a new Drosophila tumor model - PubMed
Malignant tumors trigger a complex network of inflammatory and wound repair responses, prompting Dvorak's characterization of tumors as "wounds that never heal."<sup>1</sup> Some of these responses le...
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@bilderlab @bilderlab.bsky.social · 18/10/2025
Maybe referring to a 2015 paper from our lab? pubmed.ncbi.nlm.nih.gov/25850672/ @perrimonlab.bsky.social published back-to-back: pubmed.ncbi.nlm.nih.gov/25850671/.
pubmed.ncbi.nlm.nih.gov
Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting - PubMed
Tumors kill patients not only through well-characterized perturbations to their local environment but also through poorly understood pathophysiological interactions with distant tissues. Here, we use ...
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@bilderlab @bilderlab.bsky.social · 29/09/2025
And so fabulous to dine out with former postdocs Anne Classen @classenlab.bsky.social, Thomas Vaccari @vaccarilab.bsky.social and Lucy O’Brien. Many laughs, fond memories, and talk of bright futures for all of them. #EDRC2025
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@bilderlab @bilderlab.bsky.social · 29/09/2025
Honored to share stage with all the great plenary speakers at #EDRC2025. Exciting science and great vibes from Drosophila researchers worldwide – Let’s keep the American, Euro, and APAC communities coordinated and strong!
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@bilderlab @bilderlab.bsky.social · 08/08/2025
Beautiful paper from former student @dy-chen.bsky.social now postdoc in Zernicka-Goetz lab. Human embryos, stem cell models & mice: BM heterogeneity drives AP symmetry breaking. High-end microscopy, live imaging, physical modeling, mechanistic tests. Tour de force. www.nature.com/articles/s41...
nature.com
Basement membrane perforations guide anterior–posterior axis formation - Nature Communications
Chen et al. show that in mice, extracellular matrix remodeling drives early migration of the anterior signaling center, establishing the body axis sooner than expected—a mechanism potentially conserve...
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@bilderlab @bilderlab.bsky.social · 10/07/2025
Amazing and multitalented postdoc @ongkaty.bsky.social taking time out from writing her new paper with this generous initiative. #genetics, #CRISPR, #drosophila, hallmarks of #cancer and more. For a great cause; support @flybase.bsky.social!
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Katy Ong @ongkaty.bsky.social · 10/07/2025
All proceeds from my #sciart Etsy shop will now be donated to @flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag! www.etsy.com/shop/Picosti...
gold crispr-cas9 enamel pinsdrosophila embroidered patches and enamel pinsIgM antibody enamel pins in purple and cyan
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@bilderlab @bilderlab.bsky.social · 30/06/2025
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com‬. Thanks to the leaders in the field for welcoming me as an invertebrate researcher. rdcu.be/etKdN
rdcu.be
Advancing cancer research via comparative oncology
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
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@bilderlab @bilderlab.bsky.social · 13/05/2025
New paper from superb postdoc Hui-Yu Ku about how proteases pattern extracellular matrix to precisely sculpt an organ. She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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@bilderlab @bilderlab.bsky.social · 11/05/2025
Thursday, May 22 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
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UC Berkeley MCB @berkeleymcb.bsky.social · 31/03/2025
Congrats to MCB's Diana Bautista and David Bilder for being named as AAAS Fellows @aaas.org! @bilderlab.bsky.social 👏 🎉https://news.berkeley.edu/2025/03/27/seven-faculty-members-named-fellows-of-american-association-for-the-advancement-of-science/
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@bilderlab @bilderlab.bsky.social · 25/02/2025
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details. (1/5)
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Katy Ong @ongkaty.bsky.social · 25/02/2025
Citrus tasting at the annual @bilderlab.bsky.social Lunar New Year Party 🍊
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@bilderlab @bilderlab.bsky.social · 09/01/2025
Thursday, January 30 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Join to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
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@bilderlab @bilderlab.bsky.social · 15/11/2024
Part of our lab studies #Drosophila cancer models. Delighted to announce ‘Beyond Mammals: Exploring Cancer Models” webinar held by NCI, hopefully in advance of funding opportunities. I’m speaking with @perrimonlab.bsky.social and others incl #Zebrafish and #Celegans PIs. Registration free.
events.cancer.gov
Beyond Mammals: Exploring Cancer Models Webinar Series (Overview) | Events Registration
Overview The Beyond Mammals: Exploring Cancer Models series will feature three webinars, each focused on one non-mammalian animal model and its applicability to cancer research. Each webinar will high...
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@bilderlab @bilderlab.bsky.social · 25/03/2024
Hosted a joint lab retreat with @LOBrienLab.  Shared lots of science, some lore, and a bit of history, and introduced the Stanford folks to some of the joys of Berkeley.
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@bilderlab @bilderlab.bsky.social · 25/03/2024
New lab preprint —longtime project finished in Hong Kong by new investigator @Jung_Kim_PhD. www.biorxiv.org/content/10.1...
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@bilderlab @bilderlab.bsky.social · 08/03/2024
Now accepting applications- come join us in Berkeley! #Drosophila #Celegans careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
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@bilderlab @bilderlab.bsky.social · 26/02/2024
We are hiring a research technician for June here in Berkeley.  Great for a post-bac interested in genetics, development or cancer biology.  bilderlab.berkeley.edu Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila. Please RT.
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The Interactive Fly @interactivefly.bsky.social · 20/11/2023
The Interactive Fly (www.sdbonline.org/sites/fly/ai...) is a guide to fruit fly development. It describes the literature of over 1,700 genes, dealing with developmental pathways and gene regulation. Sections include Drosophila as a model for human diseases, evolutionary biology, and neural circuits
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@bilderlab @bilderlab.bsky.social · 20/11/2023
Thomas Brodsky has arrived on Bluesky! Tom runs The Interactive Fly website and tirelessly surveys the #Drosophila literature. He won one of the inaugural Drosophila Community Service awards last year. Please follow him, like his posts, and welcome him here!
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@bilderlab @bilderlab.bsky.social · 16/11/2023
Nice @berkeleyMCB turnout tonight for @nkwhiteman.bsky.social 's triumphant talk about his book 'Most Delicious Poison'! @gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social Sabeeha Merchant
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@bilderlab @bilderlab.bsky.social · 31/10/2023
#bullettime
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@bilderlab @bilderlab.bsky.social · 31/10/2023
@bilderlab Halloween 2023: The (Extracellular) #Matrix @KatyOng1 @CajulaoJan
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@bilderlab @bilderlab.bsky.social · 07/10/2023
another awesome @bilderlab alumni talk. @d_y_chen, former @berkeleyMCB PhD, visits to describe his exciting work in @ZernickaGoetz lab and catch up with @MeganMartikPhD and @gastrulateordie. When he heads for the job market, grab him!
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@bilderlab @bilderlab.bsky.social · 28/09/2023
from student @CajulaoJan 🇵🇭
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@bilderlab @bilderlab.bsky.social · 27/09/2023
from @CajulaoJan: Fun @bilderlab outing at the ballpark last night! So far, the @SFGiantshave a 100% win rate whenever the lab is at the game😉😉
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@bilderlab @bilderlab.bsky.social · 22/09/2023
At group meeting this week, we introduced the three @bilderlab expat postdocs (Hui-yu Ku, Yoshiki Sanai, Stephan Gerlach) to good old American #Twinkies.  Check out the before and after.
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@bilderlab @bilderlab.bsky.social · 22/09/2023
Welcome Cody Doubravsky, @berkeleyMCB grad student and @Olzmannlab alum, for the first rotation!
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@bilderlab @bilderlab.bsky.social · 19/08/2023
Golden Dragon pluots edge out Dapple Jack pluots for overall best. Birthday celebrant @KatyOng1 and @CajulaoJan provide the tie breaking votes. O'Henry yellows from JJ Ramos orchard take the peach/ nectarine category. @BerkeleyBowl
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@bilderlab @bilderlab.bsky.social · 18/08/2023
Some labs do whiskey tastings… Preparing for @KatyOng1’s birthday celebration, which always coincides with stone fruit season. Here’s a partial guide to today's buy from @BerekelyBowl.   White peaches and white nectarines underrepresented, b/c really? Will post lab favorites
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@bilderlab @bilderlab.bsky.social · 10/08/2023
Reminded to post this: before @HSCRB seminar in May. I first learned to be a scientist here in the Biolabs working with @StainierLab and Wally Gilbert. Knew I had the ‘bug’ when I found myself going into lab even when I didn’t have experiments to do….
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@bilderlab @bilderlab.bsky.social · 05/08/2023
from @katyong1: My 1st postdoc paper is out @CurrentBiology. Co-authored w/Tsai-Ching Hsi, this was a fun journey: a new Drosophila tumor model, an unexpected phenotype, insight into cancer mortality & ancient origins of host response to malignancy 1/n authors.elsevier.com/a/1hIb53QW8S2Q…
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