This link will take you to a page that’s not on LinkedIn

Glucocorticoid receptor activation is a key driver of resistance of triple-negative breast cancer to both CD8+ T cells and natural killer cells during initial metastatic seeding.

Neuroimmune interactions shape host responses to infection, but the molecular role of sensory neurons during viral infection remains unclear. Roger et al. show that HSV-1-activated sensory neurons pro...

Liu et al. reveal that lactate, an aerobic glycolysis product, promotes NLRP3 inflammasome activation and pyroptosis. NLRP3 is identified as a target of lactylation, and K24 and K565 have potential to...

Cyclic guanosine monophosphate (GMP)-AMP synthase (cGAS) is a critical cytosolic DNA sensor, whose activity can be regulated by acetylation. Here, we show that nicotinamide adenine dinucleotide (NAD+)...

Un nouveau papier auquel Claire Gourin, Sébastien Hantz et Alexia Damour (membres de l’UMR Inserm 1092 RESINFIT) ont participé, est accessible en ligne. Il s’intitule « Targeting Human Cytomegalovirus...

The immunology research group “Leukocyte Traffic and the Immune Response”, led by Professor Marko Salmi, invites applications for two fixed-term postdoctoral researcher positions at the [Faculty of Me...

High quality input data is the key to successful interpretation of any scientific assay. In flow cytometry, fluorescently-conjugated antibodies allow us to simultaneously measure an incredible range ...

Published in Emerging Microbes & Infections (Vol. 14, No. 1, 2025)

Denmark is eliminating its 25% book tax after finding reading skills in steep decline. Culture Minister Engel-Schmidt: "The gift of reading is something we should give to younger generations."

Artis and colleagues show that enteric neurons produce CGRP-related ADM2 to promote intestinal tissue-protective functions in ILC2s.

Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...

Background: Aluminum is used as an adjuvant in nonlive vaccines administered in early childhood. Concerns persist about potential associations between vaccination with aluminum-adsorbed vaccines an...

Pyruvate is the end-product of glycolysis and a central metabolite involved in many biochemical pathways. However, a lack of high-performance (i.e., Δ F / F > 10) single fluorescent protein (FP)-base...

Systematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive ox...

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

Immune cells lose their cancer-fighting prowess after taking tumours’ organelles on board.

Click on the article title to read more.

Impaired mitochondrial bioenergetics in macrophages can drive hyperinflammatory cytokine responses[1][1]–[6][2], but whether this may also be caused by inherited mtDNA mutations is unknown. Here, we a...

Chronic viral infections are ubiquitous in humans, with individuals harboring multiple latent viruse