Nasal IgA1 autoantibodies against IFN-α are associated with better COVID-19 prognosis, including fewer symptoms and robust anti–SARS-CoV-2 immunity.

Nasal IgA1 autoantibodies against IFN-α are associated with better COVID-19 prognosis, including fewer symptoms and robust anti–SARS-CoV-2 immunity.

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Join us at the Keystone Symposia on B Cell and Antibody Responses, February 2027, in London, with field leaders!

Ruslan Medzhitov shares his thoughts on the balance between generating data and developing theories in immunology, with a focus on exploring the rules that govern complex systems.

2026 Summer Intern - Immunology Discovery Department Summary An internship position is available for a highly motivated and independent scientist to join the Yewdell Lab in the Department of Immunolog...

Infants from a traditional farming community exhibited antibody profiles that were found to be associated with lower incidence of egg allergy.

B-1 cells are innate-like lymphocytes that play a critical role in homeostasis by secreting natural antibodies, typically IgM, and immunosuppressive molecules such as IL-10. However, the regulation of...

FlowLITE is a flow cytometry bead-based assay that enables multiplexing and high-throughput quantification of all antibody isotypes from humans, mice, or other species, using small volumes of any fluid specimen. Here, we detail a FlowLITE protocol to quantify and characterize antibody light-chain and isotype expression in human plasma. We describe steps for titrating the capture and reveal antibodies, multiplexing assay beads, and staining samples. We then describe proced...

STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...

Nasal IgA1 autoantibodies against IFN-α are associated with better COVID-19 prognosis, including fewer symptoms and robust anti–SARS-CoV-2 immunity.

Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.

Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

Cole et al. report that adoptively transferred, tumor-specific Th17 cells engage host B cells and drive B cell proliferation and differentiation. These Th17 cells require B cells for sustained immunit...

Darwinian evolution of immunoglobulin genes within germinal centers (GC) underlies the progressive increase in antibody affinity following antigen exposure. Whereas the mechanics of how competition be...

From public health to high-tech innovation, universities are the workhorses of national progress.

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