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Parthive Patel

@gutstresslab.bsky.social
119 followers 147 following 37 posts

Patel lab, School of Cellular and Molecular Medicine, University of Bristol

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Reposted by Parthive Patel
Andrew Lin @andrewclin.bsky.social · 15/09/2026
We're hiring! Join us as a postdoc to study how the brain is optimised for sensory coding and memory Please spread the word! Apply at jobsite.sheffield.ac.uk/job/Research... Deadline: 5 October 2026 Learn more at: www.aclinlab.org
jobsite.sheffield.ac.uk
Research Associate: Neuroscience (2 Posts)
Research Associate: Neuroscience (2 Posts)
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Junior European Drosophila Investigators @fly-jedi.bsky.social · 14/09/2026
Dear #Drosophila and #NewPI community, the mentee survey for this great mentorship program is still open!
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Parthive Patel @gutstresslab.bsky.social · 05/09/2026
I am excited to share our work, recently published in PLOS Biology, in which we uncover a mechanism by which intestinal stem cells (ISCs) recognise pathogenic bacteria following infection and promote intestinal regeneration. journals.plos.org/plosbiology/...
journals.plos.org
Recognition of pathogenic bacteria by intestinal stem cells promotes adult Drosophila midgut regeneration
Bacteria infecting the intestinal epithelium are recognized by epithelial and immune cells, however the role of intestinal stem cells (ISCs) remains unclear. This study shows that adult Drosophila mid...
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@bilderlab @bilderlab.bsky.social · 17/08/2026
Now out in Annu Rev Cancer Biol: "Beyond Mice and Men." We think of cancer as a disease of humans, as well as pets 🐈‍⬛ 🐕 & lab mice. But cancer is found across the animal tree of life, including clams and fruit flies. Comparative oncology has a lot to teach us. 🧵 www.annualreviews.org/content/jour...
annualreviews.org
Beyond Mice and Men: Alternative Vertebrate and Invertebrate Models in Cancer Biology
While cancer looms large in the public and scientific minds, this can result in a quite narrow view of its range and manifestations. The centering of human clinical investigations and the popularity o...
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François Leulier @francoisleulier.bsky.social · 12/08/2026
Latest from the lab in its final form. We revisit the #Decretin concept in the light of growth adaptation to protein intake. PhD work of @longweibai.bsky.social at @igflyon.bsky.social #Drosophila
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Parthive Patel @gutstresslab.bsky.social · 12/08/2026
Excited to share our new work in The EMBO Journal! We show that intestinal stem cells directly sense tissue damage via phosphatidylserine on dying cells, activating Draper-Src-Shark-STAT signalling to drive their proliferation and shape local tissue responses to promote regeneration.
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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 11/08/2026
Read about our latest work here www.cell.com/cell/fulltex... or let Alessandro tell you all about it (link below)!
cell.com
The sex and reproductive plasticity of intestinal muscles instruct gut size
Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls ...
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Bardin Lab @bardinlab.bsky.social · 30/07/2026
A huge congratulations to Zheng and the entire Guo lab for this beautiful story! Very cool mechanism! www.nature.com/articles/s41...
nature.com
Intestinal stem cells count self-renewal divisions to switch multipotency - Nature
In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing ...
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Perrimon Lab @perrimonlab.bsky.social · 04/07/2026
New paper: Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth in Drosophila. Huang K, Miao T, Chen Y, Dantas E, Sanford J, Asara JM, Moon SJ, Hu Y, Wang K, Han M, Goncalves M, Perrimon N. Nat Commun. 2026 Jul 3. doi: 10.1038 s41467-026-75074-w.
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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 30/06/2026
Lab's latest: sculpting sex-biased metabolic territories in the intestine by tuning ploidy and lipid metabolism. Myc is to blame; Laura, Pedro and Chris found out www.cell.com/developmenta...
cell.com
Myc sustains sex-biased organ zonation in the Drosophila intestine
Amourda, Blackie, Gaspar, et al. show that sex-biased activity of Dsx and Myc shapes intestinal zonation and lipid metabolism in Drosophila. Elevated Myc activity in female enterocytes increases ploid...
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Junior European Drosophila Investigators @fly-jedi.bsky.social · 15/03/2026
Calling all #Drosophila #NewPI #researchers! A few spots remain for the upcoming JEDI Conference - and you won’t want to miss this! Every attendee gives a talk, making the exchange dynamic, personal, and highly interactive - all at a stunning venue that inspires collaboration and creativity.
View of the historic hotel Pousada Castelo in Palmela.
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Fillip Port @crisprflydesign.bsky.social · 24/03/2026
Join us in Heidelberg for your PhD! If you are excited about CRISPR genome engineering and would like to develop and apply new methods to investigate Wnt signaling in different model systems, than this project is for you. More info here: my-hbigs.uni-heidelberg.de/site/index.p... 🧪🧬🔬
Header image for the PhD position "Advanced genome engineering to investigate Wnt signaling in animals."
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Rangan Lab @ranganlab.bsky.social · 23/03/2026
Amazing new work from the Hurd lab:Sperm keep their mitochondria but lose their mitochondrial genomes. This new preprint identifies the nuclease responsible — and shows it reads DNA structure, not sequence. tinyurl.com/3npwwk37
tinyurl.com
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Parthive Patel @gutstresslab.bsky.social · 15/03/2026
A big thank you to Laura Buttitta @buttittalab.bsky.social and the Department of Molecular, Cellular and Developmental Biology at the University of Michigan for inviting me this week to present our lab’s work at the University of Bristol. I had a lovely visit.
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Parthive Patel @gutstresslab.bsky.social · 15/03/2026
Very proud of Martina Legido and Marie Srotyr from our lab for their excellent presentations of their work last week at the GSA Drosophila Research Conference (Dros26) in Chicago. 👏
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Harmit Singh Malik @harmitmalik.bsky.social · 12/11/2025
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on. (Please repost to reach a broad audience.)
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Rachel Smith-Bolton @rachelsmithbolton.bsky.social · 08/01/2026
I’d like to highlight @felicityhsu.bsky.social ‘s recently publish work in @dev-journal.bsky.social ! She showed that the regeneration blastema consists of concentric zones of differential growth and translation driven by Myc and Tor. journals.biologists.com/dev/article/...
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Bardin Lab @bardinlab.bsky.social · 03/01/2026
Happy 2026 everyone- the time has come to apply! Registration for this exciting Dev Bio conference is until the end of January!
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Giorgio Gilestro @giorgio.gilest.ro · 05/12/2025
Want to carry a PhD in London, in one of the best Universities in the world? We have two calls for PhD students to join our lab at Imperial College. Deadline January 12th. More details for applications in the link below. Feel free to keep in touch!
lab.gilest.ro
Available Jobs – gilestro laboratory
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Bardin Lab @bardinlab.bsky.social · 03/12/2025
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches May 18-22, 2026 Roscoff, France Abstract deadline: January 31, 2026 Apply here: cjm.sb-roscoff.fr/en
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 04/12/2025
Drosophila colleagues--Please submit nominations for the Larry Sandler Award. which recognizes excellent recent graduates who have completed a PhD in Drosophila research. Details are below and at this link: genetics-gsa.org/drosophila-2...
The Larry Sandler Award recognizes excellent recent graduates who have completed a PhD in Drosophila research. The awardee will receive a fantastic opportunity to present the Larry Sandler Memorial Lecture at the 67th Annual Drosophila Research Conference in Chicago, IL!

The deadline to nominate is December 15, 2025. 

Nominate Here
Eligibility
Any student completing a PhD in an area of Drosophila research between July 2024 and December 2025 is eligible. Students may be nominated by their thesis advisor, department chair, or supervisory committee member. 

Nominations
Nominations may be submitted by the student’s thesis advisor, department chair, or supervisory committee member, and should include the following:
Nominee's CV
Nominee's thesis abstract of 1–2 pages
A nomination letter directly answering the following questions:
What are the main discoveries in the nominee's thesis?
What are the intellectual and experimental contributions of the nominee to the project?
How does the thesis work advance what was previously known in the field and to previous work from your lab?
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Society for Developmental Biology @socdevbio.bsky.social · 28/11/2025
✨A gut feeling you’ll love this one 🐛 The anterior midgut of a Drosophila melanogaster 🪰larva puts on a confocal glow show! 🟢 Adult midgut progenitors 🔴 Actin 🔵 Nuclei 📸Image by Sapna Krishnakumar #FluorescenceFriday #Microscopy #DevBio
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Genetics Society of America @genetics-gsa.bsky.social · 14/11/2025
Calling thesis advisors, department chairs, and supervisory committee members! 📣 Nominate an outstanding PhD/PhD candidate working with Drosophila for the Larry Sandler Award. They'll present at #Dros26. Learn more and submit a nomination: buff.ly/mtfDbBD @peiferlabunc.bsky.social
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Bardin Lab @bardinlab.bsky.social · 19/10/2025
Starting Monday!!! If you are in Paris, feel free to drop in for this exceptional course!
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Liam Faller @liamfaller.bsky.social · 13/10/2025
First ad for a position in my new lab at the University of Bristol! If you are looking for a fully funded PhD in cutting edge science that will be based in a supportive environment, and in a great city, check out the link below! www.findaphd.com/phds/project...
findaphd.com
Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol on FindAPhD.com
PhD Project - Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol, listed on FindAPhD.com
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Bardin Lab @bardinlab.bsky.social · 07/10/2025
The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social www.cell.com/developmenta...
cell.com
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila
Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...
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Alex Gould Lab @alexgouldlab.bsky.social · 03/10/2025
Passionate about doing a PhD on metabolism in neural stem cells and their niche? The call just opened for applications for a PhD position in our lab @crick.ac.uk in London. Please repost. tinyurl.com/ysnkdrmw
Gould lab retreat 2025
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Parthive Patel @gutstresslab.bsky.social · 02/10/2025
Thank you for hosting me! It was a lovely visit.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 23/08/2025
The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
Dear Fly Community,

In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled.

The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC).

Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options.

To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum).

To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

Our immediate goals are:

1. To maintain core curation activities and keep the FlyBase website online

2. To complete integration with the Alliance of Genome Resources (The Alliance).

Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data.

At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise.

Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028.

We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide.

Sincerely,
The FlyBase Team
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Elizabeth Rideout @ejrideout.bsky.social · 22/08/2025
I watched the video and donated - it was super easy! Please donate if you’re able, and help spread the word so that we can keep this essential resource going.
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Mark A. Hanson @hansonmark.bsky.social · 14/08/2025
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate. www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Amoyel lab @amoyellab.bsky.social · 27/07/2025
Lovely work by @martinestermann.bsky.social and colleagues from the Capel lab! Together with our recent work (www.biorxiv.org/content/10.1...), this really makes a strong case that lactate is crucial to supporting male germ cells in vivo - from flies to mammals.
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corderolab.bsky.social @corderolab.bsky.social · 21/07/2025
Very happy and proud to share the latest work from our lab. Neuroendocrine control of intestinal regeneration through the vascular niche. www.sciencedirect.com/science/arti...
sciencedirect.com
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila
Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…
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The EMBO Journal @embojournal.org · 22/07/2025
How does nutrient-responsive #mTORC1 sense the key amino acid #glutamine? Gianluca Figlia, Aurelio Teleman et al @telemanlab.bsky.social identify a combination of GCN2-dependent processes triggered by secondary depletion of asparagine in glutamine-starved cells www.embopress.org/doi/full/10....
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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 19/03/2025
Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, ‪@coxlabkcl.bsky.social,‬ @priscaliberali.bsky.social and Maria Rodriguez-Colman
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Alex Gould Lab @alexgouldlab.bsky.social · 04/06/2025
Calling all European #Drosophila labs. Time for all of us, that are able, to step up to support FlyBase during this funding crisis.
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European Drosophila Society @fly-eds.bsky.social · 04/06/2025
#Drosophila @flybase.bsky.social requires emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!
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Katja Röper @katjaroeper.bsky.social · 04/06/2025
European Fly PIs: please respond to the email we sent out yesterday and help save FlyBase!
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