We are recruiting a postdoctoral scientist to join the recently opened Zandawala Lab at KU Leuven. The position is funded by an Odysseus grant from FWO (Research Foundation – Flanders). For more infor...

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In vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.

The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.

Burgmer et al. show that the pattern recognition receptors (PRRs) PGRP-LC and PGRP-LE repress key metabolic functions in the Drosophila midgut. These regulations occur independently of canonical immun...

Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dar...

α cells can generate and secrete both glucagon and GLP-1 with distinct processing enzymes to control metabolism.

Species and sex-specific differences in organ size are fundamental features of animal biology, yet the mechanisms that drive these differences remain debated. Adult female Drosophila are larger than m...

Enteroendocrine (EE) cells in the Drosophila gut produce and release multiple factors, including Allatostatin A (AstA), Allatostatin C (AstC), neuropeptide F (NPF), tachykinin (Tk), Diuretic hormone 3...

Biswas et al. show that greater dietary sugar intake promotes fat accumulation in Drosophila adult females. In the presence of dietary sugar, the activity of the conserved insulin/insulin-like growth ...

Abstract. In this study, we leverage the power and tractability of Drosophila genetics to better understand the molecular mechanisms underlying a group of

Huber et al. used live pancreas slices from donors with recently diagnosed type 1 diabetes to reveal beta cell dysfunction independent of local immune cells. Real-time imaging and molecular analyses u...

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Do not miss this call for mentees from the Drosophila community. Scan the QR Code & fill the mentee survey ! The Fly Board is excited to announce the

Tissue homeostasis is dependent on precise coordination between endocrine organs in response to changes in organism physiology. Secreted circulating factors from adipocytes (called adipokines) regulat...

Nature - Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.