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Silvia Fre lab

@frelab.bsky.social
161 followers 143 following 24 posts

Developmental biologist interested in stem cell fate institut-curie.org/team/fre

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Silvia Fre lab @frelab.bsky.social · 21/09/2026
A section on Cell Reprogramming, Regeneration and Repair: Regulatory Mechanisms of Cell Fate and Plasticity in Tissue Regeneration in Current Opinion in Genetics & Development. heck it out at the link below:
sciencedirect.com
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Silvia Fre lab @frelab.bsky.social · 01/07/2026
Congrats @priscaliberali.bsky.social @silviabarbiero.bsky.social @davidbrueckner.bsky.social @cschwayer.bsky.social @ehannezo.bsky.social ! Such a wonderful study! Happy to see that it's finally out! 😍
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Silvia Fre lab @frelab.bsky.social · 01/07/2026
So happy to be part of this distinguished community! Thank you to all colleagues @embo.org who voted for me!
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Silvia Fre lab @frelab.bsky.social · 29/06/2026
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Silvia Fre lab @frelab.bsky.social · 26/06/2026
Week-end reading? Check out our new review on development and regeneration of glandular epithelia! With two fantastic co-authors: @robinjournot.bsky.social and @candice-merle.bsky.social ! 🤗 authors.elsevier.com/sd/article/S...
authors.elsevier.com
Shared molecular and cellular programs during regeneration of glandular epithelia
An emerging concept across multiple adult tissues implies that regeneration involves the transient reactivation of developmental programs, rather than…
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Silvia Fre lab @frelab.bsky.social · 26/06/2026
So proud of my ex-student @robinjournot.bsky.social who got yet another PhD award from the British Genetics Society, thank you very much @gensocuk.bsky.social !!! 👏
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Mia Farrow @miafarrow.bsky.social · 02/03/2026
We didn’t want another war. It wasn’t explained why we began a war when Iran posed no threat. After earlier attack Trump said he “decimated” Iran’s nuclear abilities. On this attack he focused on killing leadership. Also bombed a girls elementary school. War for regime change has never gone well
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Anne Grapin-Botton @anne-grapin.bsky.social · 09/01/2026
Congratulations to Byung Ho for spearheading this work and our HFSP team! Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper. Byung Ho is looking for PI positions and he has amazing ideas and leadership. www.nature.com/articles/s41...
nature.com
Client Challenge
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Steffen Rulands @rulands.bsky.social · 05/12/2025
New preprint out now, where we track clonal cancer evolution with barcodes and predict treatment outcome.
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Levayer Lab @levayerr.bsky.social · 04/12/2025
It's been several times that I am pretty sure to witness during reviewer crosscommenting assesment mostly generated by AI (composed of hundred of unnecessary and finicky points that would lead to years of revision). For the human reviewer out there, speak up to editor if you notice this !
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Silvia Fre lab @frelab.bsky.social · 03/12/2025
Check out our beautiful story on tumour clonal dynamics with barcodes, performed in the @frelab.bsky.social by my super talented post-doc @candice-merle.bsky.social and @ivanditerlizzi.bsky.social from @rulands.bsky.social lab! #barcodes #plasticity
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Silvia Fre lab @frelab.bsky.social · 19/11/2025
Thank you @patrickpla.bsky.social ! I wish I could have been there this year #FSSCR2025
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Silvia Fre lab @frelab.bsky.social · 11/11/2025
Congratulations to Bruno Simoes and Rob Clarke! #ENBDC #breastcancer
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Silvia Fre lab @frelab.bsky.social · 27/10/2025
Thank you so much @doctoremmerson.bsky.social for liking our paper! Looking forward to discussing the implications with you!
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Robin Journot 🔬| 🎾 @robinjournot.bsky.social · 06/10/2025
Our paper is on the cover of @cp-devcell.bsky.social . Image: embryonic murine salivary-gland explants stained for fate determinants; p63 (cyan) and HES1 (yellow). Thanks to everyone involved. doi.org/10.1016/j.de...
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James Briscoe @jamesbriscoe.bsky.social · 03/10/2025
Mechanical constraints disrupt gastruloid polarisation without changing gene expression - uncouples morphogenesis & patterning Gregor & co use tunable hydrogels to show cell motility, not gene expression, drives axis formation in gastruloids journals.biologists.com/dev/article/...
journals.biologists.com
Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids
Highlighted Article: A bioinert confinement system enables dissection of how stiffness and timing shape gastruloid development, revealing uncoupling between polarization and transcriptional programs.
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Silvia Fre lab @frelab.bsky.social · 29/09/2025
So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis! Fantastic collaboration with the lab of Zuzana Koledova in Prague! @sumbalovakoledova.bsky.social It just came out online, check it out here: rdcu.be/eIIKD
rdcu.be
Contractile fibroblasts form a transient niche for the branching mammary epithelium
Nature Communications - Fibroblasts represent a heterogenous cell population but how their differences reflect their plasticity and origin is not fully understood. Here, the authors map the origin...
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Silvia Fre lab @frelab.bsky.social · 09/09/2025
Geometry first: how positional cues dictate fate in bilayered epithelia thenode.biologists.com/geometry-fir...
thenode.biologists.com
Geometry first: how positional cues dictate fate in bilayered epithelia - the Node
Behind the paper story focussed on research on early fate decisions in bilayered epithelia.
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Silvia Fre lab @frelab.bsky.social · 15/07/2025
Super happy to share the work by my post-doc Candice Merle on breast cancer obtained @institutcurie.bsky.social thanks to funding from ARC: www.fondation-arc.org/actualites/2...
fondation-arc.org
Pour mieux comprendre la transformation cancéreuse des cellules mammaires
Une exploration des mécanismes moléculaires qui permettent aux cellules mammaires de modifier leur identité donne des éléments fondamentaux pour comprendre certains phénomènes de la transformation can...
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Robin Journot 🔬| 🎾 @robinjournot.bsky.social · 01/07/2025
🧵Just out ! We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration. Here’s the story👇 authors.elsevier.com/c/1lM285Sx5g... Work done in @frelab.bsky.social at ‪ ‪ @institutcurie.bsky.social
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Silvia Fre lab @frelab.bsky.social · 17/06/2025
1000 congrats to Walid @wtklab.bsky.social !!! Plenty of success!
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Silvia Fre lab @frelab.bsky.social · 12/03/2025
Beautiful and insightful review! Congrats to @sarawickstrom.bsky.social and @clemvilleneuve.bsky.social
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Silvia Fre lab @frelab.bsky.social · 07/03/2025
Dev Bio @institutcurie.bsky.social #standupforscience
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c0nc0rdance @c0nc0rdance.bsky.social · 10/02/2025
This is a room where we turn very modest salaries and budgets (and lots of coffee) into new knowledge, life-saving innovations, and technology that feeds business growth. It's literally the loom that spins hay into gold but these numpties are suddenly worried about the cost of hay.
A research lab from Northwestern, chosen because it's generic and sort of zoomed out.  Three scientists are visible in lab coats, and there are benches and shelving, with glass along one wall showing another high-rise building nearby. Overhead fluorescents provide light.
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Walid Khaled @wtklab.bsky.social · 15/01/2025
JOB ALERT We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster. www.jobs.cam.ac.uk/job/49939/ @scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
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Financial Times @financialtimes.com · 13/01/2025
The man in charge of social media platforms used by billions should show some moral courage, writes @jemima.bsky.social www.ft.com/content/682c...
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