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Stephen Moxley

@fermentation.computer
604 followers 1.1K following 78 posts

Industrial fermentation researcher living in the Upper Valley. Passionate about humans' earliest technologies.

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Reposted by Stephen Moxley
Scientific American @sciam.bsky.social · 24/09/2026
Apple "detectives" wanted to identify a gnarly old tree growing on a remote plot of land in Maine. What they discovered was the key to a centuries-old apple mystery.
scientificamerican.com
How apple detectives solved the mystery of an ancient tree—and rewrote the history of fruit
And how they might have helped save the future of American apples
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Jerry Chen @jcsalterego.bsky.social · 14/08/2026
(guy about to invent fermentation) ummm five week rule
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n+1 @nplusonemag.com · 22/07/2026
“The Luddites see Big Tech as having eroded commonality: the common good, the social fabric, the institutions of collective interest. Luddism, as they conceive of it, is a communal, spiritual, and political project.” www.nplusonemag.com/online-only/...
nplusonemag.com
Getting Off with the Luddites | Sarah Thankam Mathews
They see Big Tech as having eroded commonality: the common good, the social fabric, the institutions of collective interest. Luddism, as they conceive of it, is a communal, spiritual, and political pr...
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Brookston @brookston.bsky.social · 22/07/2026
Beer In Ads #5297: Frankfurter Bürgerbräu Bock brookston.short.gy/mhcQQ6
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Stephen Moxley @fermentation.computer · 14/07/2026
the color of the day is orange
An orange mushroom growing up from the forest floor in front of a dry log. The stipe is thick and curved.Hundreds of small orange-yellow mushrooms growing out of a big log covered in moss. Some of the mushrooms are being attacked by a white mold.A mushroom growing out of the ground. It is a bright red orange, and is growing out of a thick white volva.A cluster of mushrooms growing on the forest floor. The mushrooms are bright orange and have thick, distinct gills.
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Sebastian S. Cocioba @atinygreencell.bsky.social · 08/07/2026
@breakliquid.bsky.social and I are delighted to say our OpenEVO preprint is finally live! An open source hand-made turbidostat that's modular, affordable, and made to be customized. Designed with love for the research community. Enjoy!!!💚 www.biorxiv.org/content/10.6...
biorxiv.org
OpenEvo: An Open-Source Platform for Automated Evolution and Analysis
Here we introduce OpenEvo, a fully open-source, low-cost turbidostat platform for automated continuous culture and directed evolution experiments. Existing tools are expensive, complex, or lack open-s...
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James Poniewozik @poniewozik.bsky.social · 03/07/2026
Medically, the beers you have while grilling don’t count. The science behind it is fascinating
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Ken Jennings @kenjennings.bsky.social · 20/05/2026
Takeout/delivery and cooking your own food are both wrong. Instead you should be extracting atmospheric dust, nutrients, and moisture using specialized microscopic hairs called trichomes.
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Jim Musil Painter @jimmusilpainter.bsky.social · 01/05/2026
My painting DRIFTLESS AREA
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alix e. harrow @alixeharrow.bsky.social · 28/04/2026
when we mourn le guin, we mourn one of our greatest writers & thinkers. but we also mourn one of our all-time greatest haters
All you do is take all the sex out, and use little short words, and little dumb ideas, and don't be too scary, and be sure there's a happy ending. Right? Nothing to it. Write down. Right on.

If you do all that, you might even write Jonathan Livingston Seagull and make twenty billion dollars and have every adult in America reading your book.

But you won't have every kid in America reading your book. They will look at it, and they will see straight through it, with their clear, cold, beady little eyes, and they will put it down, and they will go away. Kids will devour vast amounts of garbage (and it is good for them) but they are not like adults: they have not yet learned to eat plastic.
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Evan Rail @evanrail.bsky.social · 22/04/2026
You should see this NYT video article on making sake at Terada Honke in Japan. Gift link: www.nytimes.com/interactive/...
nytimes.com
See How a 350-Year-Old Brewery Makes Sake the Hard Way (Gift Article)
In Japan, the Terada Honke brewery holds fast to tradition: wild yeast, ancient songs, and a mixture of muscle and finesse.
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Rural Indexing Project @ruralindexing.bsky.social · 04/04/2026
Post Office Lisbon, IA
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Saccharomyces Genome Database @yeastgenome.bsky.social · 28/03/2026
🍻🌏🍻 Beyond commercial strains: Native #Yeast species like S. cerevisiae, Brettanomyces & Torulaspora create unique flavors in #CraftBrewing. Review shows how local microorganisms enhance terroir expression while preserving biodiversity 🧬 #YeastResearch 🧪 #SGD www.yeastgenome.org/reference/S1...
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lukelukeluke @lukelukeluke.bsky.social · 24/03/2026
Here are some nice mushrooms
Dozens of blue and silver turkey tail mushrooms grow along the side and top of a fallen log like solar panels arranged along a hillside. All photos by me
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Pablo J. Sáez @pjsaez.bsky.social · 16/03/2026
This is why we love #CalciumSignaling Look how mechanical damage triggers long range Ca2+ waves in this plant !! By @annalisabellandi.bsky.social, who is now around here ;) Full www.science.org/doi/10.1126/... @science.org #microscopy #cell #mechanobiology 🧪🔬
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Dorian Lynskey @dorianlynskey.bsky.social · 10/03/2026
The playful, prolific use of hyperlinks in online journalism (eg Slate, Pitchfork) didn’t anticipate link-rot. Now so many articles are pock-marked with cryptic allusions that some long-dead link once explained. Weird how quickly a new style comes to feel more archaic than the traditional format
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Wine Enthusiast @wineenthusiast.bsky.social · 09/03/2026
The oldest winery in the Americas is Casa Madero in Coahuila state. It sits at 5,000 feet in elevation, on soil dotted with dinosaur bones. 🦕
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Saccharomyces Genome Database @yeastgenome.bsky.social · 06/03/2026
🍺 Fixing brewing #Yeast! 🧬 Experimental evolution corrects mother-daughter separation defects in ale strain over 200 generations: ✅ fewer large clusters ✅ reduced foam accumulation during fermentation 🧪 #YeastResearch #SGD #MoreGoodPours @micropub7n.bsky.social www.yeastgenome.org/reference/S1...
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Bandcamp @bandcamp.com · 04/03/2026
This month’s Best Metal on Bandcamp includes black metal from the Palestinian diaspora, a dungeon-crawling symphonic black/doom epic, the highly anticipated return of metalcore legends, and much more.
daily.bandcamp.com
The Best Metal on Bandcamp, February 2026
Our guide to the month’s crucial heavy LPs.
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Reposted by Stephen Moxley
FEMS @femsmicro.org · 21/02/2026
🌿🍶 Happy World Kombucha Day! 🍶🌿 Cheers to the bacteria and yeasts that make kombucha fizzy, flavorful, and fascinating. Discover the microbial magic inside every brew: 👉 buff.ly/RMqTeAr
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The Delicious Legacy Podcast @deliciouslegacy.bsky.social · 13/02/2026
New episode is out, and it's a corker! Listen to The Delicious Legacy, discussing fermented dairy with Dr Simi Rezai-Ghassemi in lieu of her new book "Fermented Dairy of Central Asia" coming out this Sunday 15th! podcasts.apple.com/gb/podcast/t... #podcast #food #dairy #fermentation #cheese
podcasts.apple.com
A History of Fermented Dairy in Central Asia - From the steppe to space!
Podcast Episode · The Delicious Legacy · 12/02/2026 · 1h 2m
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Stephen Moxley @fermentation.computer · 17/02/2026
Fermentation fans: help add to this collection on @semble.so! #fermentation
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spacecowboy @spacecowboy17.bsky.social · 15/02/2026
Here is a very rough version of the For You Stats dashboard: linklonk.com/foryou It shows you 3 things: - how much you've been using For You - how many views and likes your posts got in For You - how your likes/reposts helped surface posts to other people in For You Feedback welcome
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intracranial aneurysm (spooky, scary) @chemotaxis.bsky.social · 13/02/2026
(1) this is cool (2) lol at the framing of "molecule can almost do important thing"
newscientist.com
RNA strand that can almost self-replicate may be key to life's origins
Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this
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Saccharomyces Genome Database @yeastgenome.bsky.social · 12/02/2026
🧬 Engineering stress-resistant #Yeast: Overexpressing PIR3 & SPI1 helps yeast tolerate high-concentration molasses stress from potassium/calcium ions. Modified strains showed significantly higher ethanol production than wt 🧪 #YeastResearch #SGD #Biotechnology www.yeastgenome.org/reference/S1...
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Andy Moore @aaandmoore.bsky.social · 07/02/2026
Not something you see in textbooks very often: tripolar mitosis.
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Joachim Goedhart @joachimgoedhart.bsky.social · 03/02/2026
Great to see this officially out: An mTurquoise2-Based Glucose Biosensor - works in yeast & mammalian cells and is compatible with FLIM: pubs.acs.org/doi/10.1021/...
pubs.acs.org
An mTurquoise2-Based Glucose Biosensor
Glucose is an important substrate for organisms to acquire energy needed for cellular growth. Despite the importance of this metabolite, single-cell information at a fast time-scale about the dynamics...
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Good Trailcams @goodtrailcams.bsky.social · 31/01/2026
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Ian McQue @ianmcque.bsky.social · 31/01/2026
More Burgh
Ink drawing, Edinburgh old town-inspired architecture
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Saccharomyces Genome Database @yeastgenome.bsky.social · 30/01/2026
⚡ Unconventional zinc finger binding! Newly solved structure shows #Yeast Fzf1 transcription factor uses non-canonical DNA binding strategy with its 5 zinc fingers; unusual binding pattern controls key stress response genes like SSU1 and YHB1 🧬 #YeastResearch #SGD www.yeastgenome.org/reference/S1...
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Sardonicus @sardonicus.eu · 24/01/2026
'1970s canned goods label designs, from The Art of the Label by Robert Opie.'
tinned food with various designs,some very simple other more complex
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Jeff VanderMeer @jeffvandermeer.bsky.social · 22/01/2026
your calm moment
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WinRAR Earle @tommchenry.bsky.social · 04/01/2026
2-minute comic
Drawing of the artist in a sweater at a desk, scowling at an empty sketchbook page. TEXT: “Maybe the REAL problem is I don’t have the right system of little notebooks…”
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merryn @merryn02.bsky.social · 19/12/2025
🏺How was #malt discovered? I should've presented this at the World Neolithic Congress last year but was not able to. So I submitted it to PAST, the newsletter of The Prehistoric Society. It was published last month in the November issue. It should be online soon! merryn.dineley.com/2025/12/the-...
merryn.dineley.com
The importance of being malted: making malt and malt sugars from cereals in the Palaeolithic.
The Shanidar Cave: one of the places where the ancient magic of malt was first discovered. (image: Wikimedia)  I should have presented this...
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colors.bsky.social @colors.bsky.social · 25/12/2025
#F47C10
a square filled in with strong orange color  #f47c10.
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ASM @asm.org · 15/12/2025
The 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart
"The Hidden Power of Microorganisms: No microbes, no life…”“Self-portrait of Saccharomyces Cerevisiae.”“Circles of Life: Microbes in Motion.”
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Gary Hornseth @garyhornseth.bsky.social · 14/12/2025
Trade catalog images American Type Founders Co. Elizabeth, New Jersey 1950 Images: Type, Typewriter and Typography Collection via @archive.org; archive.org/details/ATF1...
A rectangular box labeled “Semi-circles and Quadrants,” containing a variety of them. A rectangular box labeled “Gothic Percent Marks, wide and narrow,” containing a variety of them. A rectangular box labeled “Spartan Medium Fractions,” containing a variety of them. A rectangular box labeled “Heavy Round Corners,” containing a variety of them.
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Stephen Moxley @fermentation.computer · 10/12/2025
twenty one people in the past MONTH??
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The Onion @theonion.com · 09/12/2025
Hometown Unveils Disappointing Microbrewery theonion.com/hometown-unveils-disap…
Hometown Unveils Disappointing Microbrewery
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Stephen Moxley @fermentation.computer · 05/12/2025
this would fix me, etc etc
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Maitreya Dunham @maitreya.bsky.social · 26/11/2025
Fun new preprint from the lab, headed up by two incredible undergraduate researchers: Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast. www.biorxiv.org/content/10.1...
biorxiv.org
Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast
The budding yeast, Saccharomyces cerevisiae, is the workhorse of the brewing industry. Brewers have domesticated a vast array of different strains with traits that complement the beers they wish to br...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 26/11/2025
AWESOME technical goal. This is exactly the direction to go on this problem, and worth taking a risk on.
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Manuel Lera-Ramirez @manu-lera.bsky.social · 24/11/2025
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software ✅ Free 🔓 Open Source 🧬 More cloning methods than SnapGene 🤖 Can be automated with python 👨‍🔬 Built by a researcher — for researchers! 👉 Check it out at opencloning.org
A cloning strategy as depicted in the OpenCloning website
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Jeremy Bartlett @jeremybartlett.bsky.social · 20/11/2025
My latest blog post: Golden Conecap, Conocybe aurea. A rather scarce fungus in the UK and a very nice find this summer when I was watering a neighbour's greenhouse at the allotments. www.jeremybartlett.co.uk/2025/11/20/g... #Fungi #FungiFriends
Golden Conecap, Conocybe aurea. Two picked fruitbodies.Golden Conecap, Conocybe aurea. in situ, in a pot of compost in an allotment neighbour's greenhouse.Golden Conecap, Conocybe aurea. Spores (x1000, in water).Golden Conecap, Conocybe aurea. Cheilocystidia (xw100, stained in Congo red).
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Thorn @coelliptic.bsky.social · 20/11/2025
I use Celsius because I care about how water feels. Sorry for being an empath
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Jack A Gilbert @gilbertjacka.bsky.social · 17/10/2025
Microbes sustain all ecosystems yet they’re nearly absent from conservation frameworks. The @IUCN Microbial Conservation Specialist Group aims to change that. Honored to co-chair this global effort. Great @nytimes piece by Carl Zimmer: www.nytimes.com/2025/10/17/s...
nytimes.com
Save the Whales. But Save the Microbes, Too.
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Stephen Moxley @fermentation.computer · 01/11/2025
very cool! I can’t wait to get some more tools in the leaflet toolbox—I think I’m most excited about image galleries but audio will be awesome as well
lab.leaflet.pub
Polls in publications — what block should we add next? - Leaflet Lab Notes
Help us test our newest block type…by voting on what block to add next in Leaflet!
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