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Phil Kyriakakis

@breakliquid.bsky.social
2.2K followers 3.2K following 747 posts

Senior Research Scientist at Stanford Bioengineering | Taking apart and building biology.🧪

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Phil Kyriakakis @breakliquid.bsky.social · 17/08/2026
ysph.yale.edu/news-article...
ysph.yale.edu
Universal Health Coverage Could Save $1 Trillion and 114,000 Lives Every Year, Yale Study Projects
A single-payer universal health care system could cover every American, save more than 100,000 lives a year, and still cost $1 trillion less than the system it
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optimisticsoap.bsky.social @optimisticsoap.bsky.social · 09/08/2026
Libraries make us a harder target for authoritarianism. Equal access to info, ideas, and space that doesn’t require a purchase to belong. Also: using the library means money stays in your community instead of streaming out to Amazon. 📚 What’s checked out on your card right now?
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Phil Kyriakakis @breakliquid.bsky.social · 10/07/2026
Two preprints up in the same week! This one was from work I finished in 2014, my PhD work! FINALLY. It describes the biochemistry of the yeast glucokinase, which is in the actin family, and forms ATP/ADP-regulated glucose-6-phosphate filaments! www.biorxiv.org/content/10.6...
biorxiv.org
Glk1p is an actin fold metabolic enzyme whose polymerization is sensitive to nucleotide state
The actin fold is present in enzymes ranging from sugar kinases to chaperones. Previous work on the actin fold metabolic enzyme, glucokinase (Glk1p) in S. cerevisiae found it could form filaments in r...
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Phil Kyriakakis @breakliquid.bsky.social · 09/07/2026
OooooopenEvo! What a journey building this @atinygreencell.bsky.social , our baby is born! We hope this serves as a nice research tool as well as a teaching tool for biology, electronics and more!
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Digital Brain @yourdigitalbrain.bsky.social · 03/07/2026
Peacock spiders are only 4mm long, but their courtship dance rivals any bird of paradise. Australia has over 90 species of these tiny, ultra-colorful performers.
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Phil Kyriakakis @breakliquid.bsky.social · 30/06/2026
Is this cool or gross? www.nature.com/articles/s41...
nature.com
Underwater Suit-Wearing Cyborg Insect Capable of Hours-Long Diving and Terra-Aqua Travel - Nature Communications
A wearable diving suit enables terrestrial cyborg cockroaches to maintain respiration and locomotion underwater for up to 3 hours. This biohybrid system facilitates sustained exploration through hybri...
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Phil Kyriakakis @breakliquid.bsky.social · 26/06/2026
I thought maybe I invented this term, but its already a thing! Its better than PCR, GCR! “Gratitude Chain Reaction uses the psychological ripple effect of appreciation to inspire a cycle of reciprocal kindness”
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Sebastian S. Cocioba @atinygreencell.bsky.social · 14/06/2026
I made a webpage to try SpliceCraft out directly in your browser in a little sandbox. No download or install needed to try it. Gonna make a tutorial mode to walk people through the features soon. Enjoy! splicecraft.bio
splicecraft.bio
SpliceCraft — the in-terminal plasmid workbench
Design, clone & mutate plasmids in a mouse-friendly terminal workbench. Everything runs on your own computer — no cloud, no account.
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Stacey Ogden 🦔 @labogden.bsky.social · 03/06/2026
Make some noise about this 🧪 www.npr.org/2026/06/03/n...
npr.org
President Trump seeks control of science funding
The White House Office of Management and Budget is moving to take more control of billions of dollars in federal grants. Critics say the proposed change would jeopardize the integrity of U.S. science.
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Phil Kyriakakis @breakliquid.bsky.social · 01/06/2026
WHY?
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Sebastian S. Cocioba @atinygreencell.bsky.social · 29/05/2026
SPLICECRAFT v1.0 IS LIVE!!!!!!!!!!!! Open your terminal and type in "pipx install splicecraft" if you want to try it out, then spam "splicecraft update" often as I push updates frequently. A labor of love for the community I adore. Enjoy! 💚
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Phil Kyriakakis @breakliquid.bsky.social · 10/05/2026
Exam question idea: give a question with AI answering it. The student needs to explain what is wrong with the AI answering.
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Phil Kyriakakis @breakliquid.bsky.social · 01/05/2026
Night market in Santa Clara this weekend!!! www.santaclaraca.gov/recreation-c...
santaclaraca.gov
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Phil Kyriakakis @breakliquid.bsky.social · 24/04/2026
Evolution of my print. Printing TPU 85a is way harder than I expected.
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Phil Kyriakakis @breakliquid.bsky.social · 24/03/2026
I accidentally made a better stirring system
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Phil Kyriakakis @breakliquid.bsky.social · 24/03/2026
Much needed good news www.canarymedia.com/articles/cle...
canarymedia.com
Suddenly, the US manufactures a ton of grid batteries
Energy storage is surging on the U.S. grid — and now the country has more than enough battery-making factories to meet that booming demand.
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Phil Kyriakakis @breakliquid.bsky.social · 14/03/2026
Either I like to eat scorpions or I don’t…
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Phil Kyriakakis @breakliquid.bsky.social · 02/03/2026
Claude is way better anyway
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Phil Kyriakakis @breakliquid.bsky.social · 02/03/2026
Mass surveillance and killer robots are not for me.
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Phil Kyriakakis @breakliquid.bsky.social · 28/02/2026
My new cup holders, which change color when heated.
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Andy Rivkin @asrivkin.bsky.social · 23/02/2026
🔭🛰️🧪
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Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 21/02/2026
Exciting! Stanford researchers have developed a UNIVERSAL INTRANASAL vaccine. A study in mouse models shows that vaccinated mice were protected against Covid & other coronaviruses. Still a long way to humans. This study was #NIH funded. A potential game changer. 🧪 med.stanford.edu/news/all-new...
med.stanford.edu
One vaccine may provide broad protection against many respiratory infections and allergens
Stanford Medicine researchers and their colleagues invented a new vaccine that protects mice from respiratory viruses, bacteria and allergens — the closest yet to a universal vaccine.
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Wim Meijer @wimgmeijer.bsky.social · 19/02/2026
The system acts as near-permanent archival storage for backup of critical data. It stores 4.8 terabytes, the equivalent of around 2 million printed books Data survives for 10,000 years at a temperature of 290ºC and much longer at room temperature. 🧪🦠 www.nature.com/articles/d41...
nature.com
Microsoft team creates 'revolutionary' data storage system that lasts for millennia
Researchers use mini plasma explosions to encode the equivalent of two million books into a coaster-sized device. The method could preserve research data for millennia with minimal storage costs.
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Tapani Hopkins @tapani-hopkins.bsky.social · 18/02/2026
I suspect one reason science social media has done reasonably well post-Twitter is that it didn't get (too badly) scattered. There's a viable population on both Bluesky and Mastodon. Here's one (opt-in) way of of connecting those two populations to make sciencesky even bigger. 🧪
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Nigel Goldenfeld @nigelgoldenfeld.bsky.social · 18/02/2026
🧪⚛️ Ever wondered what would happen if you thrashed around in a water tank, creating a blob of turbulence, and then watched it spread and gradually dissipate energy? So did we. But we did the experiment, now out in PNAS and on the cover! It only took us 7 years ... www.pnas.org/doi/10.1073/...
Pictured are 3D trajectories of turbulent particles colored by speed, showing two large vortices. Takumi Matsuzawa, Minhui Zhu et al. observed the expansion and decay of a blob of turbulence created in the center of a tank of still water. The results revealed steep fronts separating turbulent and undisturbed regions, the nonlinear transport and decay of the turbulent blob, and a persistent signature of turbulence late into the decay process. According to the authors, the analysis could help provide insight into processes ranging from star formation to fusion reactors. See the article by Matsuzawa, Zhu et al. e2526858123. Image credit: Takumi Matsuzawa.
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Phil Kyriakakis @breakliquid.bsky.social · 17/02/2026
Why is Windows do this every time my computer updates?
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Tim O'Connell @tinosaurs.bsky.social · 15/02/2026
Okay, but for #BlueSky to gain a fraction of the value in networking that we once enjoyed over at #Twitter, we all need to be reposting pretty much everything we see. Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky url: academic.oup.com/icb/article-...
academic.oup.com
Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky
Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For
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Phil Kyriakakis @breakliquid.bsky.social · 07/02/2026
🤞
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Phil Kyriakakis @breakliquid.bsky.social · 03/02/2026
Another cool pipette rack pattern!
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Colette Delawalla, PhD @cdelawalla.bsky.social · 27/01/2026
Wow. This is devastating. www.science.org/content/arti...
science.org
U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office
A Science analysis reveals how many were fired, retired, or quit across 14 agencies
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Phil Kyriakakis @breakliquid.bsky.social · 01/02/2026
Another 3d printed pipette rack
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Phil Kyriakakis @breakliquid.bsky.social · 24/01/2026
My new pipette holder
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Phil Kyriakakis @breakliquid.bsky.social · 23/01/2026
This figure really grabs your attention!
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Phil Kyriakakis @breakliquid.bsky.social · 16/01/2026
Is there an easy way to get saw RNA-seq data and turn it into a table of differentially expressed genes? Like, without installing 12 programs and taking a bioinformatics course?
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Phil Kyriakakis @breakliquid.bsky.social · 07/01/2026
I hope their antibodies are better than their legos. The design is very flimsy, but I enjoyed the challenge.
An antibody lego from abcam
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Phil Kyriakakis @breakliquid.bsky.social · 03/01/2026
Taaaaalllllll
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BWJones @bwjones.bsky.social · 01/01/2026
Surprise mother$#@%er! Q: What does this mean for neural systems to understand them? A: We absolutely need the wiring diagram. All synapses, chemical and electrical. #Connectomics
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Phil Kyriakakis @breakliquid.bsky.social · 23/12/2025
They win for best use of parafilm: www.nature.com/articles/s41...
nature.com
Fluorine-free binder-based dry thick electrodes with Parafilm® M toward sustainable and efficient battery manufacturing - Nature Communications
Fluorine-containing binders in battery dry electrode processing raise environmental concerns regarding restrictions on per- and polyfluoroalkyl substances. Here, authors show that a fluorine-free bind...
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Phil Kyriakakis @breakliquid.bsky.social · 19/12/2025
👀
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Phil Kyriakakis @breakliquid.bsky.social · 19/12/2025
How to write an R01 type grant that isn’t “too high risk”, but is still exciting, novel?
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 15/12/2025
This is VERY cool! 🧪
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Phil Kyriakakis @breakliquid.bsky.social · 13/12/2025
Son got sick (severe cold) in Taiwan, no insurance. Saw a doctor in 10min, $15 including the acetaminophen and ibuprofen the doctor gave us. How much would that be in the USA?
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Phil Kyriakakis @breakliquid.bsky.social · 07/12/2025
More squirrel.
A plump black squirrel eating a french fry at a park
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Phil Kyriakakis @breakliquid.bsky.social · 01/12/2025
This website was meant for scientist runners! They literally cut the shoes in 1/2 and do all sorts of testing on them! runrepeat.com/saucony-ride...
runrepeat.com
Cut in half: Saucony Ride 17 Review (2024)
Saucony Ride 17 review: The Saucony Ride 17 is more than just a minor update—it's a significant overhaul, especially with the all-new midsole that enhances energy return and responsiveness. In our lab...
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Oded Rechavi @odedrechavi.bsky.social · 27/11/2025
PI sharing with his student a competitor's ERC that he's reviewing
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Phil Kyriakakis @breakliquid.bsky.social · 27/11/2025
Wow, this is really cool! www.nature.com/articles/s41...
nature.com
All-optical visualization of specific molecules in the ultrastructural context of brain tissue - Nature Biotechnology
Pan-expansion microscopy of tissue combines staining of proteins and lipids with immunolabeling.
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Phil Kyriakakis @breakliquid.bsky.social · 22/11/2025
Update, I grabbed 10 colonies and combined into one @plasmidsaurus.bsky.social reaction. All of them were too small and most were the same, the TE inserted in the same place. So screening colonies won't likely work.
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Jaeseung Hahn @jaeseunghahn.bsky.social · 20/11/2025
Boolean logic-gated protein cargo release! @coledeforest.bsky.social's group previously used the molecular topology with proteases as inputs to release fluorescent proteins from hydrogels, and they now extended the platform for other protein cargoes! 🧬 onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
Boolean Logic‐Based Controlled Release of Bioactive Proteins with Diversified Inputs
We recombinantly express autonomously compiling Boolean logical operators enabling controlled release of therapeutically relevant proteins in response to precise user-defined combinations of environm...
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Phil Kyriakakis @breakliquid.bsky.social · 19/11/2025
Has anyone had this show up in their plasmid, and how to prevent it? "E. Coli IS10L Transposon"
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Phil Kyriakakis @breakliquid.bsky.social · 15/11/2025
AI can mess things up real fast! 😭
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