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Research at UHN

@uhnresearch.ca
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Research news from Canada's largest research hospital. 🔗 uhnresearch.ca

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Research at UHN @uhnresearch.ca · 3h
Read about the latest findings from Canada’s largest #research hospital in @uhn.ca ’s Research Spotlight newsletter: ▶️ New treatment for bipolar depression ▶️ #AI tool for cancer treatment ▶️ Retaining registered practical nurses + More 🔗: www.uhnresearch.ca/nrx_newslett...
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Research at UHN @uhnresearch.ca · 8h
🚨Out today in @natimmunol.nature.com, a study from @pmresearch-uhn.bsky.social’s Dr. Anastasia Tikhonova identifies distinctive early changes in the bone marrow environment in people with age-related blood #StemCell mutations, before blood cancer develops. ⬇️
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Research at UHN @uhnresearch.ca · 28/09/2026
Out today in @natbiotech.nature.com, a study from Dr. Bowen Li (@pmresearch-uhn.bsky.social) shows a new strategy for improving the non-viral delivery of large mRNA cargo for gene editing—an approach with the potential to expand the reach of gene editing therapies. 🔗: www.nature.com/articles/s41...
nature.com
Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing - Nature Biotechnology
Lipid nanoparticles are improved by including RNA cargo size in the design process.
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Research at UHN @uhnresearch.ca · 25/09/2026
Congratulations to Dr. Tak Mak, Senior Scientist at @pmresearch-uhn.bsky.social, on receiving the German Society of Immunology's German Immunology Prize. 🎉 As the Society's highest scientific honour, the award recognizes outstanding contributions to immunology. 🔗: idw-online.de/en/news877636
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Research at UHN @uhnresearch.ca · 21/09/2026
Postdoctoral researchers play an important role in advancing discovery and innovation at @uhn.ca. During #PostdocAppreciationWeek, we're highlighting members of UHN's postdoctoral community and the work they're leading across a range of research areas. 🧵⬇️
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Research at UHN @uhnresearch.ca · 18/09/2026
New research from @pmresearch-uhn.bsky.social shows how chemotherapy can cause long-term damage to bone & and blood-forming cells in the bone marrow by triggering inflammation—offering insight into why many cancer survivors face lasting health challenges. 🔗: www.uhnresearch.ca/news/9-18-20...
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Princess Margaret Cancer Centre @pmresearch-uhn.bsky.social · 17/09/2026
Congratulations to Dr. Long Nguyen on being named Canada's Top 40 Under 40 by @financialpost.com for leading a research program uncovering how cancer cells evolve, adapt, and develop resistance to treatment, to improve patient outcomes. @uhnresearch.ca @uhn.ca
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Research at UHN @uhnresearch.ca · 17/09/2026
Can a low-cost depth camera make balance rehabilitation more accessible? Researchers at @kiteuhn.bsky.social found a depth camera performed similarly to traditional force plates used in balance training, suggesting a more accessible rehabilitation approach. 🔗: www.uhnresearch.ca/news/9-16-20...
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Research at UHN @uhnresearch.ca · 16/09/2026
#NewPublication🚨 Researchers at @pmresearch-uhn.bsky.social have developed a new #AI tool that can identify rare immune cells with the ability to recognize and respond to #cancer. 🔗 Read more: www.uhnresearch.ca/news/9-16-20...
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UHN Research & Innovation Cores @uhncores.bsky.social · 11/09/2026
The Princess Margaret Living Biobank is celebrating 10 years of advancing cancer research through patient-derived models. Join researchers, collaborators, and the UHN community on October 8 for food, refreshments, remarks, and a celebration of impact, discovery, and innovation. @uhnresearch.ca
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Research at UHN @uhnresearch.ca · 10/09/2026
1/ Why does deep brain stimulation (DBS) affect people with #Parkinsons differently? Researchers at @kbi-uhn.bsky.social found that DBS affects brain-wide networks and that outcomes differ across two common targets. The findings could help personalize care. 🔗: www.uhnresearch.ca/news/9-07-20...
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Research at UHN @uhnresearch.ca · 09/09/2026
Congratulations to @uhn.ca’s Drs. Laura Dawson and Jan Seuntjens, who have been elected to the Royal Society of Canada—Canada’s leading body of scholars, researchers & artists! 🎉 Their transformative work in radiation oncology is shaping the future of health. 🔗 : www.uhnresearch.ca/news/9-09-20...
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Research at UHN @uhnresearch.ca · 08/09/2026
1/ Improving care goes beyond clinical expertise. A @tier-uhn.bsky.social study identified ways continuing professional development programs can improve teaching on topics such as health equity and power dynamics to advance collaboration and patient care. 🔗: www.uhnresearch.ca/news/9-08-20...
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Research at UHN @uhnresearch.ca · 04/09/2026
A new study from @uhn.ca’s Peter Munk Cardiac Centre shows that the protein ERG helps protect blood vessels from changes that drive atherosclerosis—the buildup of plaque in the arteries. Findings could point to future therapeutic strategies to protect arteries. 🔗: www.uhnresearch.ca/news/9-04-20...
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Research at UHN @uhnresearch.ca · 03/09/2026
1/ Four infusions. Two weeks. One important step toward expanding treatment options. A @uhn.ca-led clinical trial found that ketamine reduced symptoms in adults with treatment-resistant #BipolarDepression and was well tolerated throughout the study. 🔗: www.uhnresearch.ca/news/9-02-20...
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Research at UHN @uhnresearch.ca · 27/08/2026
1/ Researchers at @pmresearch-uhn.bsky.social have developed an RNA-based therapy that can repair disease-causing genetic "stop" signals. Out today in @science.org, the approach has the potential to treat certain genetic disorders such as cystic fibrosis. 🔗: www.uhnresearch.ca/news/8-27-20...
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Research at UHN @uhnresearch.ca · 25/08/2026
Congratulations to @uhn.ca’s Drs. Niall Ferguson, Jennie Johnstone, Michael Milosevic, & Gang Zheng on being elected as Fellows of the Canadian Academy of Health Sciences. Their research is improving health outcomes in Canada and beyond. 🔗: www.uhnresearch.ca/news/8-25-20...
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Research at UHN @uhnresearch.ca · 25/08/2026
People with #ALS often face uncertainty about disease progression and care management. @kiteuhn.bsky.social researchers found that access to personalized information and more patient-centred support may help people make more informed choices about their care. 🔗: www.uhnresearch.ca/news/8-25-20...
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Research at UHN @uhnresearch.ca · 24/08/2026
1/ A new study from @pmresearch-uhn.bsky.social introduces a new #AI model that could make gene editing more effective. DeepCC9 predicts which CRISPR-Cas9 guide RNAs will perform best while revealing the sequence patterns behind successful gene editing. 🔗: www.uhnresearch.ca/news/8-24-20...
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Krembil Brain Institute 🧠 @kbi-uhn.bsky.social · 18/08/2026
Get a behind-the-scenes look as some of this year's summer students @kbi-uhn.bsky.social @dkjei-uhn.bsky.social @schroeder-uhn.bsky.social as they share what it was like working in the lab and reflect on their research experiences this summer >> bit.ly/4gflcOG @uhn.ca @uhnresearch.ca
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Ajmera Transplant Centre UHN @transplant-uhn.bsky.social · 14/08/2026
Ajmera Transplant Centre Research Day 2026 brought our transplant community together to share discoveries, celebrate excellence, and advance the future of transplantation. Read more: ow.ly/Pyc250ZzQ6N #Transplantation #Research #UHN
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Research at UHN @uhnresearch.ca · 13/08/2026
1/ A new blood test-based method developed by researchers at @pmresearch-uhn.bsky.social could detect and classify metastatic breast cancer without the need for invasive tissue biopsies. 🔗 Read more: www.uhnresearch.ca/news/8-04-20...
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Donald K. Johnson Eye Institute @dkjei-uhn.bsky.social · 12/08/2026
We are pleased to announce the Vision Research Symposium 2026: Innovations in Retina, bringing together Toronto's vision science community to share knowledge, celebrate research, and foster collaboration across disciplines. @uhn.ca @uhnresearch.ca @kbi-uhn.bsky.social @uoftmedicine.bsky.social
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Research at UHN @uhnresearch.ca · 12/08/2026
Through UHN STEM Pathways, 37 high school students gained hands-on research experience and explored their future STEM aspirations. 🔗 This #YouthDay, learn about 4 of these summer students and their experiences at @uhn.ca: www.uhnresearch.ca/news/8-12-20... #NextGenUHN
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Research at UHN @uhnresearch.ca · 11/08/2026
#ICYMI Recently, the Hon. Nolan Quinn, Michelle Cooper, and Mohamed Firin joined us to learn about transplant innovations and advanced MRI technologies at @uhn.ca, which are shaping the future of patient care. Watch some of the highlights from the visit below ⬇️
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Research at UHN @uhnresearch.ca · 07/08/2026
#ICYMI: With $20.7 million from the Canadian Institutes of Health Research's Spring 2026 Project Grant Competition, 26 @uhn.ca-led projects will advance research and help shape the future of health care across Canada. 🔗 Learn more about these impactful projects: www.uhnresearch.ca/news/8-07-20...
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Research at UHN @uhnresearch.ca · 07/08/2026
Read about the latest findings from Canada’s largest research hospital in @uhn.ca’s Research Spotlight newsletter: ▶️ #CognitiveTraining to improve balance ▶️ Strategies for #HeartFailure care ▶️ #BrainStimulation treatments for people with severe OCD + More 🔗: www.uhnresearch.ca/news/8-07-20...
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Research at UHN @uhnresearch.ca · 05/08/2026
1/ Registered practical nurses (RPNs) are playing an increasingly important role in Canadian hospitals. A @tier-uhn.bsky.social study highlights the need for greater role clarity, professional development, and workplace supports to strengthen retention. 🔗: www.uhnresearch.ca/news/8-05-20...
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Research at UHN @uhnresearch.ca · 31/07/2026
New research from @schroeder-uhn.bsky.social suggests that overall #osteoarthritis burden may influence recovery after surgery for lumbar spinal stenosis. 🦴 The findings could help improve treatment planning and patient outcomes. 🔗 Read more: www.uhnresearch.ca/news/7-31-20...
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Krembil Brain Institute 🧠 @kbi-uhn.bsky.social · 31/07/2026
The CRANIA 2026 Conference brought together multidisciplinary experts and highlighted #neuromodulation and #DBS research last July 23-24, 2026. 🧠 This year's conference had a record number of speakers, sponsors, and demand from attendees. ⚡️ @crania-toronto.bsky.social
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Research at UHN @uhnresearch.ca · 28/07/2026
1/ Chronic kidney disease (CKD) cases are rising globally. New research co-led by @uhn.ca is highlighting the impact on patients with cirrhosis, finding worse patient outcomes, and reinforcing a need for proactive disease management. 🔗 Read more: www.uhnresearch.ca/news/7-28-20...
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Research at UHN @uhnresearch.ca · 27/07/2026
Last week, @uhnresearch.ca had the pleasure of welcoming the Hon. Nolan Quinn, Michelle Cooper, and Mohamed Firin to showcase research supported by the Ontario Research Fund—including the EVLP system and advanced MRI innovations. Stay tuned for a full recap! -- @uhn.ca
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Research at UHN @uhnresearch.ca · 24/07/2026
Take a look at how @uhn.ca’s SHERLOCK study—supported by the Peter Gilgan Foundation—is lighting a new path in #PrecisionCare and helping detect cancer recurrence earlier with a blood test. 🔗 Learn more: www.uhn.ca/corporate/Ne... @pmresearch-uhn.bsky.social
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Krembil Brain Institute 🧠 @kbi-uhn.bsky.social · 20/07/2026
🎉 Please join us in welcoming Dr. Richard Roth to UHN’s @krembilresearch! Dr. Roth joins us as a Scientist, focusing on the interplay between synaptic plasticity and neural circuit adaptation, and how these processes shape motor learning.    🔗 Learn more about his research: www.motor-plasticity.org
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Donald K. Johnson Eye Institute @dkjei-uhn.bsky.social · 17/07/2026
🎉 Please join us in welcoming Dr. Wendy Xin @droligo.bsky.social to @dkjei-uhn.bsky.social and @kbi-uhn.bsky.social! Learn more about her research: www.oligodendrocyte.org @uhnresearch.ca @uoftmedicine.bsky.social (1/2)
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Research at UHN @uhnresearch.ca · 20/07/2026
🚨 #NewPublication What would patients improve about their hospital stay? A @uhn.ca study surveyed patients & caregivers in Canada and found communication, care delays, and inclusivity matter most. The findings can help guide quality improvement efforts. 🔗: www.uhnresearch.ca/news/7-20-20...
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Research at UHN @uhnresearch.ca · 08/07/2026
After cancer treatment, one question remains: Is it truly gone? Backed by the Peter Gilgan Foundation, SHERLOCK at @pmresearch-uhn.bsky.social is uncovering cancer earlier—through a simple blood test. 🔗 Read the CBC exclusive: www.cbc.ca/news/health/...
cbc.ca
Can you ever truly cure cancer? Canadian researchers are using blood biopsies to find out | CBC News
A Toronto-based team is launching a massive, years-long research project to study liquid biopsies, a novel technology meant to catch tiny traces of tumour DNA in the blood. The goal? Finding better wa...
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Research at UHN @uhnresearch.ca · 07/07/2026
1/ After stroke, regaining mobility and balance can be challenging. A new study from @kiteuhn.bsky.social found that more reactive balance training was associated with improved balance control in people recovering from stroke. 🔗 Read more: www.uhnresearch.ca/news/7-07-20...
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Research at UHN @uhnresearch.ca · 03/07/2026
#ICYMI UHN secured a total of $1.7M to recruit 13 international researchers to advance Canadian innovation in #AI, #StemCells, #cancer, and more. This funding was awarded through the Canada Impact+ Research Training Awards. 🔗: www.uhnresearch.ca/news/7-03-20...
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Research at UHN @uhnresearch.ca · 02/07/2026
1/ As AI-powered surgical tools advance, it is essential to consider their usability, cost, and environmental impact in real-world clinical settings. In a new study, @tier-uhn.bsky.social researchers evaluated how two AI surgical guidance systems perform in simulated operating rooms. 👇 @uhn.ca
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Research at UHN @uhnresearch.ca · 29/06/2026
Congratulations to Elly Zhou, inaugural recipient of @uhn.ca's Lawrence and Nora Pentland Fellowship. Based at the Ajmera Transplant Centre, her work uses AI to model human lungs and improve how therapies are tested. We are grateful to the Pentlands for making this opportunity possible.
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Research at UHN @uhnresearch.ca · 26/06/2026
1/ New findings from @pmresearch-uhn.bsky.social reveal how DNA sequences called transposable elements can help leukemia stem cells survive treatment and drive relapse, paving the way for new therapeutic strategies. 🔗 Read more: www.uhnresearch.ca/news/6-26-20...
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Research at UHN @uhnresearch.ca · 25/06/2026
For patients with heart failure, deciding on a hospital care strategy is critical. A new study from @uhn.ca’s Peter Munk Cardiac Centre found that a risk-based care strategy with coordinated follow-up improves outcomes equally for males and females. 🔗 Read more: www.uhnresearch.ca/news/6-25-20...
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Research at UHN @uhnresearch.ca · 24/06/2026
AI is transforming health care—but how do we ensure it’s safe, fair, and trustworthy? The Cancer Digital Intelligence team from @pmresearch-uhn.bsky.social has developed AFFRM-AI, a practical framework for responsible #AI in clinical care. 🔗 Read more: www.uhnresearch.ca/news/6-23-20...
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Research at UHN @uhnresearch.ca · 23/06/2026
1/ New research from @kiteuhn.bsky.social finds that cognitive training may improve balance and cognitive multitasking in older adults. Still, benefits are limited by hearing ability—providing insights into reducing fall risk and supporting independence. 🔗: www.uhnresearch.ca/news/6-23-20...
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Research at UHN @uhnresearch.ca · 18/06/2026
Chronic kidney disease (CKD) is on the rise worldwide—and over half of cases are not linked to diabetes. New results from a trial published in three journals, co-authored by UHN’s Dr. David Cherney, found that finerenone can slow CKD progression and reduce heart risks across diverse cases of CKD. 🧵
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Krembil Brain Institute 🧠 @kbi-uhn.bsky.social · 18/06/2026
📢 Big news! Join us in celebrating Dr. Mark Reed, Scientist @kbi-uhn.bsky.social, on receiving funding from @cabhiinnovates.bsky.social! 🧠✨ His project explores new treatments for Alzheimer’s & dementia by targeting neuroinflammation & crossing the blood-brain barrier. 👏 @uhn.ca @uhnresearch.ca
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Research at UHN @uhnresearch.ca · 12/06/2026
Last month, UHN STEM Pathways brought STEM to life at #ScienceRendezvous with @sinaihealthtoronto.bsky.social! 200+ visitors explored robotics, the human body, & more. Thank you to the volunteers who created an afternoon full of discovery! 🔗 Read more: www.uhnresearch.ca/news/6-12-20...
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Research at UHN @uhnresearch.ca · 11/06/2026
#ICYMI 6 @uhn.ca researchers received Canada Research Chair funding to advance research on retinal regeneration, obesity and diabetes, tumour microenvironments, cancer radiotherapy, virtual care technology, and physician education. 🎉 🔗 Read more: www.uhnresearch.ca/news/6-11-20...
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Research at UHN @uhnresearch.ca · 10/06/2026
New research co-led by UHN sheds light on why some people with high genetic risk for schizophrenia develop the condition while others do not—offering new insight into disease biology and potential pathways for earlier diagnosis.🧬 🔗 www.uhnresearch.ca/news/6-09-20...
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