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Jay Hennig

@jhennig.bsky.social
1.6K followers 548 following 150 posts

Computational neuroscientist interested in how we learn, and dad to twin boys Asst prof at Baylor College of Medicine www.henniglab.org

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Reposted by Jay Hennig
Matthijs Pals @matthijspals.bsky.social · 8h
What kind of dynamics underlie sequence working memory? In the last project of my PhD we developed and analysed RNNs fitted to multi-session single-unit data of macaques. Now out on: www.biorxiv.org/content/10.6... With @jakhmack.bsky.social and data from Chen et al., Neuron 2024. [1/4]
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Michael Okun @michael-okun.bsky.social · 30/09/2026
A project that I've been working on for the last couple of years (on & off), dealing with the question of how firing rates of neuronal populations change (1/6).
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Franziska Brändle @frabraendle.bsky.social · 29/09/2026
Incredibly excited to announce that I’m starting my own research group at Justus-Liebig-Universität in Gießen as part of the excellence cluster “The Adaptive Mind”! 🥳 I'm looking to fill the first PhD position. If you’re interested, apply here: tinyurl.com/38p3h22p Please spread the word! 🙏
jobs.uni-giessen.de
Doctoral student (m/f/d) Computational Motivation – Justus-Liebig-Universität Gießen
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Sandra Romero Pinto @sromeropinto.bsky.social · 25/09/2026
Happy to have this finally out! TL;DR: The evolution of beliefs over time can be formulated as a dynamical system, and OFC neural activity appears to implement this system with its own dynamics. These emerge without explicit supervision—when animals learn to predict value in simple Pavlovian tasks
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Mattan S. Ben-Shachar @mattansb.msbstats.info · 24/09/2026
This quote by haunts me. From Wilcox's "Introduction to Robust Estimation and Hypothesis Testing" #stats
To begin, distributions are never normal. For some this seems obvious, hardly worth mentioning, but an aphorism given by Cram´er (1946) and attributed to the mathematician Poincar´e remains relevant: “Everyone believes in the [normal] law of errors, the experimenters because they think it is a mathematical theorem, the mathematicians because they think it is an experimental fact.”
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Sam Gershman @gershbrain.bsky.social · 24/09/2026
I'm excited about this work that an amazing undergrad, @ariazhang.bsky.social, did with me and @tomerullman.bsky.social: www.biorxiv.org/content/10.6... Aria showed how a neural net can discover abstractions for intuitive physics and use its own reliability estimates to decide when to deploy them.
biorxiv.org
Reliability-guided meta-control in intuitive physics
Intuitive physical reasoning is an important part of daily life, but the computations underlying it remain debated. Some prominent accounts propose intuitive physics relies on mental simulation, with ...
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samuel mehr @mehr.nz · 24/09/2026
my favourite form of grad student flex: you roll up to lab meeting with pilot data which demonstrates that the study is working exactly as expected, but you didn't tell anyone ahead of time. the lab finds out all at once, together
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Nicholdav @nicholdav.bsky.social · 24/09/2026
sorry folks @ashleyjuavinett.bsky.social et al. just proved that neurons are canonically non-binary
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Jay Hennig @jhennig.bsky.social · 24/09/2026
Amazing work by @sromeropinto.bsky.social ! Sandra found that in Pavlovian tasks with hidden states, neural population dynamics in mouse OFC resemble beliefs/state-inference
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Nima Dehghani @neurovium.bsky.social · 23/09/2026
XJ Wang left ?!? What a loss for the US (and NYU) Everyday I get some news that a prominent scientist is leaving. The chaos of the science budget and downfall of the American science are spiralling down very fast. This is disheartening. www.eurekalert.org/news-release...
eurekalert.org
World-renowned computational neuroscientist professor Xiao-Jing Wang joins HKU as Chair Professor
The University of Hong Kong (HKU) announces the appointment of Professor Xiao-Jing Wang, a pioneer in theoretical and computational neuroscience, to its faculty as a Chair Professor. Professor Wang wi...
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Tomer Ullman @tomerullman.bsky.social · 22/09/2026
new preprint: "Directing large language models to follow the letter or spirit of the law" arxiv.org/pdf/2609.23083 (by Qian , Li, Chen, Murthy @soniakmurthy.bsky.social , Belinkov, and me) this is particularly cool/important, and I'm allowed to say it because it was headed by @pqian.bsky.social
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Mitchell Ostrow @neurostrow.bsky.social · 21/09/2026
We also built a fast, differentiable form of DSA — ∂DSA. With this, we showed we can train RNNs online with DSA to learn novel, never-before-hypothesized solutions to computational tasks! (Stay tuned for future work on this too!) (8/)
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Ann Kennedy @antihebbiann.bsky.social · 21/09/2026
There are more submissions to ICLR this year (at least 62,000) than in all previous years of the conference combined.
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PessoaBrain @pessoabrain.bsky.social · 21/09/2026
𝗥𝗲𝗰𝗼𝗿𝗱𝗶𝗻𝗴 𝗮𝗰𝗿𝗼𝘀𝘀 𝗯𝗿𝗮𝗶𝗻 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘀 𝗯𝗿𝗮𝗶𝗻𝘄𝗶𝗱𝗲 𝗿𝗲𝗽𝗿𝗲𝘀𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻𝘀 Neuroscientists now recording across the brain are finding what fMRI revealed in humans. Signals are not localized but often all over the brain. (NB: non, it's not everything, everywhere) #neuroskyence www.biorxiv.org/content/10.6...
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Caswell Barry @caswell.bsky.social · 19/09/2026
Masa's paper is out in Hippocampus. The left-right alternation of hippocampal theta sequences at T-maze choice points, much loved as a 'planning' signal, falls straight out of MEC dynamics. Well done @masahironakano.bsky.social, fun project with @clopathlab.bsky.social doi.org/10.1002/hipo.70131
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Weiji Ma @weijima.bsky.social · 17/09/2026
NEW PREPRINT ON LAB CULTURE: What is it, how is it related to mentorship, and how to document it? With @rademaker.bsky.social and Chris Pfund. osf.io/preprints/ps...
osf.io
OSF
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Mark Wagner @mark-j-wagner.bsky.social · 16/09/2026
Granule cells predict future dopamine reward. Delayed climbing-fiber signals can reinforce the action that precedes it. Our paper, led by Benjamin Filio, is out today in Nature Neuroscience. www.nature.com/articles/s41... Public PDF: rdcu.be/RscCNeXvkXAa
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saulsch.bsky.social @saulsch.bsky.social · 15/09/2026
Here is a graph.
A graph of time (in years) versus number (of papers submitted to the ArXiv in August). Shows an increase in most categories of perhaps 1.5 going from 2025 to 2026.
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Monosov Lab @monosovlab.bsky.social · 15/09/2026
New preprint! 🧠 How do reward, risk & information preferences relate to psychopathology? How do they vary across decisions about gains vs. losses? 1,954 people! Hundreds of economic choices each + transdiagnostic assessment of mental health symptoms online. www.biorxiv.org/content/10.6...
biorxiv.org
A dimensional link between gain-loss economic preferences and psychopathology
Human decision-makers differ in how they value and trade off reward, risk, and information when evaluating future gains and losses, and these preferences are central to well-being. However, how multi-...
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Patrick Mineault @patrickmineault.bsky.social · 14/09/2026
Are virtual flies playing Beat Saber? SM64? Doom? No. The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown: www.neuroai.science/p/are-flies-...
neuroai.science
Are flies playing Beat Saber?
What a time to be alive!
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Jay Hennig @jhennig.bsky.social · 14/09/2026
This is such cool work, especially the idea that on-manifold geometry is "imposed by the circuit's intrinsic dynamics" and not just stim encoding. We think something similar happens in human hippocampus—though tbf we haven't characterized the stimulus encoding dims yet bsky.app/profile/jhen...
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Terence Tao @teorth.bsky.social · 11/09/2026
A group of 25 Fields Medalists, including myself, have made a joint declaration on Math and AI: mathandai.org . We welcome additional signatories. See also this article in the Economist announcing the declaration: www.economist.com/science-and-...
mathandai.org
Declaration — Math and AI
Read the declaration and add your name.
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Arthur Prat @arthurpr4t.bsky.social · 09/09/2026
We derived six laws of psychophysics from a single efficient-coding equation. The laws include Weber's law; scaling laws in visual working memory (which had been noted before, but with unclear theoretical justification); Wei & Stocker's law of human perception; arthurprat.com/pdfs/Prat-Ca...
arthurprat.com
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Lindsey Powell @lindseypowell.bsky.social · 09/09/2026
UCSD Psychology is hiring!! We’re seeking a new assistant professor colleague who studies high-level human cognition, broadly construed. Please share and/or apply! apol-recruit.ucsd.edu/JPF04646
apol-recruit.ucsd.edu
Assistant Professor in High-level Human Cognition
University of California, San Diego is hiring. Apply now!
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Ben Hayden @benhayden.bsky.social · 09/09/2026
New paper from the Neurosurgery Research Team at BCM! “Neural geometry in the human hippocampus enables generalization across spatial position and gaze” led by @assiachericoni.bsky.social! 🧵 www.cell.com/neuron/abstr...
cell.com
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
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Jieyu Zheng @jieyusz.bsky.social · 04/09/2026
How fast can mice learn complex mazes? With @mameister4.bsky.social we reveal memory, generalization, latent learning, and remote credit assignment of mice in the Manhattan Maze. Do mice born without a cortex or hippocampus have them too? Check it out! www.biorxiv.org/content/10.6...
biorxiv.org
Rapid spatial cognition in mice, with and without neocortex and hippocampus
Rapid learning, memory, and generalization are often attributed to circuits of the neocortex and hippocampus, but their specific role remains unclear. To examine these cognitive abilities together in ...
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John C. Baez @johncarlosbaez.bsky.social · 03/09/2026
Terence Tao says: there's an emerging consensus on how to solve one of the $1,000,000 Millennium prize problems. He says AI may help and lead to new insights - but it may solve the problem in a way that gives no new insights! Read what he wrote here: mathstodon.xyz/@tao/1172078...
Terence Tao from https://mathstodon.xyz/@tao/117207849921390904 :

But there is now a scenario in which an autonomous AI harness, backed by an enormous amount of computational resources, performs this entire iteration internally, and ends up producing the final ansatz, and thence the solution to the Navier-Stokes regularity problem, while the AI company running the harness keeps the process to arrive at that ansatz almost completely out of public view.  Technically, one of the most prominent open problems in mathematics would now be solved; but there would be almost no value added to mathematics as a consequence.  It is theoretically possible that with some herculean (and heavily AI-assisted) additional effort by a third party, some portion of the process could be reverse-engineered to recover some actual insight and understanding from the solution; but this would be a far less efficient process than if the solution had been obtained via a diverse combination of both human mathematicians and machine assistance as mentioned above. (5/6)
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Constantin Rothkopf @c-rothkopf.bsky.social · 03/09/2026
Pouring a cup of coffee looks trivial. It isn’t. Humans effortlessly control nonlinear liquid dynamics across different vessels and speeds—while robots still struggle. In our new preprint, we ask how the human motor system solves this everyday control problem. 1/5
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Benjamin Cowley @benjocowley.bsky.social · 01/09/2026
CSHL is hiring a new BioAI faculty member, part of a multi-year hiring process for the Foundations of the Future. We need to fill a new BioAI building, come join! www.cshl.edu/about-us/car...
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Tom McCoy @rtommccoy.bsky.social · 01/09/2026
🤖🧠NEW PAPER🧠🤖 (The result of an 8-year project!) LLMs seem very different from symbolic systems. Yet LLMs excel in symbolic domains (e.g., language/code/math). How do they do it? Our finding: LLM representations have implicit symbolic structure! Link in thread ⬇️ 1/n
Overview of the paper. 
Title: The Emergent Symbolic Structure of Artificial Neural Networks
Authors: Tom McCoy, Paul Soulos, Tal Linzen, Paul Smolensky
Left: Neural networks encode information in vectors (there is then an image of a vector), yet they excel at tasks long thought to require symbolic structure (there is then an image of a symbolic representation, specifically a syntax tree). How do LLMs do it?
Right: We find that LLM representations can be closely approximated with symbolic structures. This approximation lets us edit the structure of an LLM’s output by editing the structure of its internal representations, as shown. There is then an image of two edits to LLMs. In the first one, the original input is 3 + 6 * 8, with an answer of 51. But if we swap the positions of the 3 and the 6, the output becomes 30. In the second one, the original input is a Python command repeating the list [Z, U] three times, producing [Z, U, Z, U, Z, U]. But if we edit the input in a way that adds a Q at the end of the input, the output becomes [Z, U, Q, Z, U, Q, Z, U, Q].
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Marc Coutanche @marccoutanche.bsky.social · 01/09/2026
We are recruiting an Assistant Professor in Cog Neuro/Cog Psych to join us at Rice! Please spread the word! apply.interfolio.com/192080
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Jay Hennig @jhennig.bsky.social · 31/08/2026
Lesson learned: If you want double spacing in Overleaf/latex just like MS Word, \doublespacing is not it! You want: \usepackage{setspace} \setstretch{2}
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Jay Hennig @jhennig.bsky.social · 31/08/2026
Just realized that creating a double-spaced document in Latex gives you more lines-per-page than double-spacing in Word. If a grant says your application must be "8 pages double-spaced"...will I get penalized if I didn't use Word's stricter definition? 😬😬😬
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Tal Golan @talgolanneuro.bsky.social · 28/08/2026
How can we design experiments that make computational models disagree? One section of our new @natrevneuro.nature.com Review with @kriegeskorte.bsky.social and @heikoschuett.bsky.social examines studies that used stimulus sets designed to elicit distinct predictions from competing models. 1/16
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Joost de Jong @joost-de-jong.bsky.social · 28/08/2026
🧵 What is the briefest visual response we can elicit? Intuitively, that's the response to the briefest stimulus, aka a flash, right? 📸 No, we can go even briefer! Using a deceptively simple technique, we designed stimuli that elicit briefer-than-brief responses www.biorxiv.org/content/10.6...
biorxiv.org
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Victoria Bosch @initself.bsky.social · 28/08/2026
The URH: representations are shaped by the slice of reality a system can sense, act on, and cares about: its Umwelt. Alignment is explained by overlap of ecological constraints, not convergence onto a veridical world model. Universality cannot explain both similarity *and* systematic difference. 6/n
Top: Our visualization of the Funktionskreis (see von Uexkull). Umwelts are shaped by development and learning under constraints, through interaction of the system and the world, mediated by sensors and effectors.
Bottom: Both human and ANN vision are shaped by analogous biological and artificial constraints. The content and effect of these constraints determine representational alignment between compared systems.
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Victoria Bosch @initself.bsky.social · 28/08/2026
Are brains and artificial neural networks converging onto universal representations? There is a seductive idea making the rounds in NeuroAI / machine learning: train systems well enough, and they all converge on the same representation of reality (i.e. a unique world model). We have thoughts™ 1/n
cell.com
The Umwelt Representation Hypothesis: rethinking Universality
Recent studies reveal striking representational alignment between artificial neural networks (ANNs) and biological brains, leading to proposals that all sufficiently capable systems converge on univer...
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Harrison Ritz @hritz.bsky.social · 27/08/2026
Our task-switching paper is now out at Current Biology! www.cell.com/current-biol... We find that that our brains reset to a task-neutral state between trials, providing flexibility when the upcoming task is uncertain. RNNs also learn this strategy, but only when trained to switch tasks.
schematic of how a brain might reset to a neutral state between trials
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Adrien Peyrache @apeyrache.bsky.social · 28/08/2026
Interesting piece in which @itsneuronal.bsky.social suggests dropping the common bit-per-spike metric & reporting the duration of held-out data to validate a model Seems to be just 120ms of data for a sharply tuned, high firing rate head-direction cell, i.e. just 3-4 spikes arxiv.org/abs/2607.28779
arxiv.org
Bits per Spike as a Betting Game: An Interpretable Unit for Held-Out Log-Likelihood in Neural Data Analysis
Held-out log-likelihood is the standard currency for comparing statistical models of neural spike trains, and is often reported as bits per spike relative to a homogeneous Poisson baseline. The units ...
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Rui Ponte Costa @somnirons.bsky.social · 27/08/2026
How does the brain continually adapt? Fresh in @natureportfolio.nature.com our super exciting collaboration with @mark-j-wagner.bsky.social showing that the cerebellum contextualises cortical dynamics enable multi-task learning: www.nature.com/articles/s41...
nature.com
Granule cells reorient cortical trajectories to separate contexts - Nature
Simultaneous imaging of premotor cortex and cerebellar granule cells in mice learning two skills in parallel shows that trajectories generalize in cortex but coherently reorient apart in granule cells...
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Marlene Cohen @marlenecohen.bsky.social · 25/08/2026
Now out at PNAS! The final version includes a smart analysis suggested by a reviewer showing that biomarkers collected in blood track our neural population metrics. A very exciting connection between basic neurophys and translational approaches. Congrats to all! www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Anatoly Shashkin💾 @dosnostalgic.bsky.social · 26/08/2026
Original Microsoft Solitaire graphics by Susan Kare.
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The Transmitter @thetransmitter.bsky.social · 25/08/2026
The Transmitter's summer reading list highlights upcoming neuroscience books and other notable titles from this year—with books by @romainbrette.bsky.social, @susanacarmona.bsky.social, @markdhumphries.bsky.social, David Susillo and more. #neuroskyence By @franciscorr25.bsky.social bit.ly/4qz0oXj
thetransmitter.org
The Transmitter’s reading list for 2026
Our summer reading list includes books on the Human Brain Project, the neuroscience of motherhood and the career of a Huntington’s disease researcher.
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TheHerm @herminator12.bsky.social · 25/08/2026
Live your life so that even the freakin' Library of Congress mourns you.
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Library of Congress @librarycongress.bsky.social · 25/08/2026
The Library is devastated to learn of the passing of Dolly Parton, a music legend and titan of children's literacy. Her Imagination Library program has earned multiple Library Literacy Awards and, in 2018, she visited us to donate its 100 millionth book to our collection and host a story time. 🦋❤️
Dolly Parton reads to children in the Library’s Great Hall in 2018. Photo by Shawn Miller.
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Fenying Zang @fenying-zang.bsky.social · 25/08/2026
Very excited to share that the first paper from my PhD has now been published in Nature Communications!    Does the ageing brain become noisier? We analysed >18,000 neurons across 16 brain regions to find out.   www.nature.com/articles/s41... 1/5
nature.com
Age-related changes in behavioural and neural variability in a decision-making task - Nature Communications
How the reduction of variability in response to sensory stimuli changes with ageing is not fully understood. Using large-scale neural recordings in mice, this study shows that ageing is linked to more...
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Matt Henderson @matthen.com · 25/08/2026
Playing with the P, I, and D weights in a PID controller. P = Proportional: push in proportion to how far the ball is off I = Integral: accumulate historical error to fix slow drift D = Derivative: respond to how fast the error is changing, to damp it
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Nico Schuck @nicoschuck.bsky.social · 24/08/2026
I enjoyed writing this piece for The Transmitter. AI is a seismic change for science. What we make of it is up to us, but it’s a decision we can only make collectively. I hope more labs, and the field at large, will engage in finding a shared view of how we want to use AI.
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Elliot H Smith, PhD @neurosmith.bsky.social · 21/08/2026
New preprint from the lab about time time resolved ensemble computations and geometrical motifs that facilitate rapidly learned inference. skeeprint 🧵: 1/
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Venki Murthy @neurovenki.bsky.social · 21/08/2026
New preprint! Taking inspiration from ML where train-test split is critical to show that an agent is generalizing rather than just memorizing, we did some experiments that suggest mice have an inductive bias towards generalization. Led by an amazing graduate student Ningjing Xia. See what you think!
biorxiv.org
An inductive bias for generalization in mouse olfactory learning
Animals must generalize from limited experience, yet behavioral experiments in the laboratory setting rarely assess whether or how rapidly they generalize. This contrasts with machine learning systems...
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