Sign in

The Picower Institute for Learning and Memory at MIT

@picowerinstitute.bsky.social
268 followers 111 following 150 posts

A community of more than 250 MIT researchers dedicated to understanding the fundamental mechanisms of how the brain works and applying that insight to disease.

PostsRepliesMedia
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 30/09/2026
In six talks at our Aging Brain Initiative symposium Sept. 25, researchers from across MIT described projects aimed at advancing the understanding of and interventions against neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS picower.mit.edu/news/symposi...
Earl Miller speaks from a podium in MIT"s Buildig 46
032
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 23/09/2026
💼We're hiring! We're looking for an Executive Director to help drive scientific strategy and research development while leading our administrative and financial teams. picower.mit.edu/about/careers #neuroscience #careers #jobs
picower.mit.edu
Careers
011
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 18/09/2026
Join us a week from today for our afternoon symposium: Innovation for the Aging Brain. Six great talks + Posters. Registration will close on Monday: picower.mit.edu/events/aging... #neuroscience #aging
Poster lists speakers: Alan Jasanoff, Oleta Johnson, Laura Kiessling, Earl Miller, Ritu Raman and Giovanni Traverso
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 14/09/2026
We’ve been so touched to hear from so many people since our founder Susumu Tonegawa died. As a tribute to his legacy, MIT has established The Susumu Tonegawa Memorial Fund. Gifts can be made via giving.mit.edu/susumu-toneg... or by emailing memorial-gifts-office@mit.edu.
In a black and white picture, Susumu Tonegawa sits at a table piled with papers and writes on a pad with a pen. Behind him is a whiteboard full of math.
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 09/09/2026
How the brain keeps its options straight at decision time: Ensembles of neurons encode information to maximize clarity throughout the process. picower.mit.edu/news/how-bra... #neuroscience
A flat cartoon profile of a head with a speak bubble coming out of it. Inside the bubble are check and x marks.
141
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 01/09/2026
A new atlas of the striatum reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia, addiction and other disorders. It could guide new drug treatments. youtu.be/eQmEKrBMvmo #neuroscience
youtu.be
A 'roadmap' of the striatum
YouTube video by The Picower Institute for Learning and Memory
110
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 19/08/2026
New theory! The brain's ability to generate cognition and consciousness arises from analog computations carried out by electrical waves. Review in JNeurosci led by @earlkmiller.bsky.social : picower.mit.edu/news/cogniti... #neuroscience
picower.mit.edu
Cognition and consciousness arise from analog computations, says new theory
The brain's ability to generate quick, nimble volitional thought—and a unified awareness of thought and experience—arises from analog computations carried out by electrical waves, MIT neuroscientists ...
1175
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 17/08/2026
Flexible brain circuits can switch between different tasks. Neuroscientists have discovered circuits in the prefrontal cortex that can be repurposed to store different types of information. picower.mit.edu/news/flexibl... #neuroscience
132
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 14/08/2026
High-speed microscopy reveals electrical activity across the brain. New technique, demonstrated in Zebrafish, could help scientists learn how the entire brain works as a whole. picower.mit.edu/news/high-sp... #neuroscience
142
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 13/08/2026
“The brain does not evaluate each new event from scratch." picower.mit.edu/news/brain-c...
picower.mit.edu
Brain circuit keeps tabs on what just happened to aid judgement of what’s happening now
With the tough job of trying to keep track of what’s going on in front of it, the brain relies not only on what it sees, but also a comparison with what it just saw. A new study in mice pinpoints the ...
120
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 13/08/2026
Every year, undergrads from across the country visit MIT labs, including ours, to gain research experience. Learn more about the MSRP-Bio program through the lens of two students' experiences in the lab of @jtroylittleton.bsky.social www.youtube.com/watch?v=tpia... #neuroscience #stem
youtube.com
Summer research in MSRP-Bio
YouTube video by The Picower Institute for Learning and Memory
010
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 10/08/2026
Congratulations to Emery N. Brown on earning an honorary doctorate from University of Coruna (Galicia, Spain) honoring his research on anesthesia and the brain! udc.gal/gl/novas/Mar... #neuroscience
050
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 29/07/2026
With Mass. Women’s Health Award, team will study how Alzheimer’s risk varies with hormone replacement picower.mit.edu/news/mass-wo... #Alzheimers #WomensHealth
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 20/07/2026
Congratulations to Emery N. Brown on being named an Institute Professor at MIT. It's MIT's highest faculty honor! picower.mit.edu/news/mit-nam... @mitbcs.bsky.social
picower.mit.edu
MIT names Emery N. Brown an "Institute Professor," its highest faculty honor
Brown, a renowned neuroscientist, anesthesiologist and statistician, has made numerous seminal contributions to basic science and clinical care alike. He joins two other professors in earning the hono...
090
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 15/07/2026
We are heartbroken to have lost our founder, who provided so much inspiration, but we are all honored to carry on the science he loved so much. picower.mit.edu/news/picower... #neuroscience #biology
picower.mit.edu
Picower Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86
Tonegawa made landmark discoveries about how the immune system generates antibody diversity and how the brain forms memories.
02919
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 09/07/2026
Video: How Your Brain Beats AI on the Energy of a Light Bulb Earl K. Miller Neuroscience of Democracy Symposium May 19, 2026 MIT's Picower Institute for Learning and Memory youtu.be/uC8QlVgNIac #neuroscience @picowerinstitute.bsky.social
youtu.be
How Your Brain Beats AI on the Energy of a Light Bulb - Earl K. Miller
YouTube video by Earl Miller
1218
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 07/07/2026
News alert: New paper! Electric fields help guide neural activity, even from moment to moment “The brain is a rollicking sea of electrical influences” picower.mit.edu/news/electri... work by @pinotsislab.bsky.social #neuroscience
picower.mit.edu
Electric fields help guide neural activity, even from moment to moment
A new study adds evidence that electric fields in the brain help to organize and shape underlying neural activity via “ephaptic coupling.”
0177
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 20/06/2026
New results! A new method that analyzes brain waves and spike timing together. This lets us pinpoint exactly which rhythms neurons are locking to. BAYESIAN STATE-SPACE MODEL FOR JOINT INFERENCE OF OSCILLATORY DYNAMICS AND POINT-PROCESS COUPLING doi.org/10.64898/202... #neuroscience
doi.org
BAYESIAN STATE-SPACE MODEL FOR JOINT INFERENCE OF OSCILLATORY DYNAMICS AND POINT-PROCESS COUPLING
Under a range of behavioral and physiological conditions, spike times and local field potential (LFP) oscillations exhibit phase coupling within specific frequency bands. Classical measures such as sp...
14513
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 18/06/2026
Speedy, spiraling electrical waves may be key to brain’s information flow Rotating neuronal waves are built into brain anatomy and help coordinate far-flung regions, mouse imaging study suggests www.science.org/content/arti... #neuroscience
science.org
Speedy, spiraling electrical waves may be key to brain’s information flow
Rotating neuronal waves are built into brain anatomy and help coordinate far-flung regions, mouse imaging study suggests
35315
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 11/06/2026
How do brains integrate sensory evidence over minutes to generate adaptive behaviors? A new Flavell lab preprint identifies C. elegans circuits that integrate aversive smells during foraging to control specific behavioral responses. www.biorxiv.org/content/10.6... #neuroscience @mitbcs.bsky.social
A grayscale image shows a tiny worm slithering from upper right to bottom left. Its head crosses a faint line labeled "copper boundary"
073
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 03/06/2026
Congratulations to three students who have earned MIT HEALS Graduate Fellowships! Jessie Xiao (studying alpha synuclein in Parkinson's disease), Evan Ruesch (developing tools for optical physiology), & Emma Ibanez (studying sensory neurons in reproductive system). #neuroscience #brain
Jessie Xiao, Evan Ruesch and Emma Ibanez smile as they stand along a railing in MIT's Building 46.
020
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 02/06/2026
A recap of our recent symposium "The Neuroscience of Democracy," ICYMI: picower.mit.edu/news/symposi...
picower.mit.edu
Symposium speakers examine how understanding the brain could improve the functioning of democracy
Combining insights from the debates of American civics to the discoveries of neuroscience labs, experts honed in on ways that brain science research could inform efforts to improve political participa...
030
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 26/05/2026
Myriam Heiman named the director of The Picower Institute for Learning and Memory. Heiman, who studies neurodegenerative diseases such as Huntington’s disease and Parkinson’s disease, will lead the institute beginning July 1. picower.mit.edu/news/myriam-... #neuroscience
Myriam Heiman stands along blue glass windows in MIT's Building 46
1126
Reposted by The Picower Institute for Learning and Memory at MIT
SfN Journals @sfnjournals.bsky.social · 14/05/2026
Register for the next #ResearchInConversation webinar, "Development of Cortical Somatostatin Innervation," May 26, 12PM EDT 🔗 Register: neuronline.sfn.org/scientific-resea… 📄 Read the paper: doi.org/10.1523/JNEUROSCI.1870-25.2…
023
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 18/05/2026
Congratulations to Professor Emery N. Brown, who this morning received an honorary doctorate of medical sciences from Yale in recognition of his #neuroscience, #statistics and #anesthesiology research.
Emery Brown in academic regalia stands facing the dais as his citation is read in front of a massive crowd at Yale's commencement.
0120
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 15/05/2026
🐈Amid finals and in advance of graduation, two of our most prestigious 'Purr-fessors,' Kinje and Torbie, held office hours at a cat cafe today, arranged the lab of Professor Myriam Heiman. Attendees also enjoyed boba, macarons and cat crafts. Thanks to MIT's School of Science!
Two women kneel on either side of a cat tree where a calico cat is snacking on a treatA man in an MIT hat leans down to offer a snack to a dark grey cat hiding in a fuzzy grey boxA bunch of people crowd around a conference room table stacked with boba teas and other snackscloseup on a man's hands as he colors in a flat wooden cat using a blue magic marker
031
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 14/05/2026
The rules neurons follow to make sense of what we see. A new study in mice by @SurLabMIT discerns the rules that neurons use to turn what could be a cacophony of input into a functional arrangement for processing vision. picower.mit.edu/news/rules-n... #neuroscience
130
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 06/05/2026
Read a fascinating new interview in Nautilus with @earlkmiller.bsky.social and @lisafeldmanbarrett.com based on their new paper in Nature Reviews Neuroscience, "Categorization is 'baked' into the brain." nautil.us/how-does-you...
nautil.us
How Does Your Brain Know a Cat Is a Cat?
How Does Your Brain Know a Cat Is a Cat?: A conversation with renowned neuroscientists Lisa Feldman Barrett and Earl Miller about categories, “folk psychology,” beginner’s mind, and thinking fast and ...
010
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 01/05/2026
Happy "Cat-sual Fur-day"! The lab of Professor Myriam Heiman treated our whole building to a cat cafe featuring Torbie, Cleo, and Kinje. Hoomans also got Boba tea!
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 01/05/2026
The company's headband uses EEG to measure brain activity while people enjoy their normal sleep routines. The data are processed by machine learning to monitor the effects of treatments, find signs of disease & create patient cohorts for clinical trials. news.mit.edu/2026/beacon-... #neuroscience
news.mit.edu
Beacon Biosignals is mapping the brain during sleep
Beacon Biosignals is creating a model to help diagnose and treat brain disorders, based on data collected while people sleep at home. The firm was founded by MIT alumnus Jake Donoghue and former MIT r...
001
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 27/04/2026
#AI for #Alzheimers: MIT-based team releases first AI foundation model for Alzheimer's prevention picower.mit.edu/news/mit-bas...
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 20/04/2026
How neurons sense bacteria in the gut: To understsand the mechanisms that enable the bacterial microbiome to influence brain function, a new study examines the mechanisms at work in a model “bacterial specialist,” C. elegans. picower.mit.edu/news/how-neu... #neuroscience @mitbcs.bsky.social
Little worms wriggle through a red-tinted gel.
242
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 14/04/2026
A new study of Rett syndrome highlights potential for personalized treatment. MIT researchers tracked how two different mutations alter neural circuit development in organoids and how each could be addressed with distinct potential therapeutics. picower.mit.edu/news/rett-sy... @mitbcs.bsky.social
Three different views of a cerebral organoid-a roundish arrangement of brain cells in a lab culture-show the cells lit up in different colors such as green and magenta
110
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 14/04/2026
At the Alana Down Syndrome Center's symposium last week, 7 researchers from MIT, Rutgers and the University of São Paulo shared the work they are doing to help people with trisomy 21 throughout their lifespan. picower.mit.edu/news/alana-d... @mitbcs.bsky.social #downsyndrome
picower.mit.edu
Alana Down Syndrome Center symposium highlights studies from brain to heart
Seven researchers from MIT, Rutgers University and the University of São Paulo shared the research they are doing to help people with trisomy 21 throughout their lifespan.
000
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 13/04/2026
A new paper in @natrevneuro.nature.com challenges decades of dogma about how and why the brain boils down what it sees, hears, smells, tastes and feels into categories. picower.mit.edu/news/complet... #neuroscience #cognition @mitbcs.bsky.social
picower.mit.edu
A complete rethinking of how our brains use categories to make sense of the world
Challenging the classic view, two cognitive scientists argue in a new review that categorization is not a late, specialized stage of sensory processing. Instead, it is a core function operating at eve...
1279
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 10/04/2026
How do nervous systems produce behaviors? A new MIT study provides a detailed mechanistic mapping of exactly what happens in the brains of C. elegans worms when they “follow their nose” to savor attractive odors or avoid unappealing ones. picower.mit.edu/news/navigat... #neuroscience
1104
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 03/04/2026
What does it mean that Assistant Professor Sara Prescott is "Committed to Caring"? She cultivates a lab where students are challenged to think boldly while feeling genuinely supported, and where they are seen not only as researchers, but as whole people. Read more: picower.mit.edu/news/leading...
picower.mit.edu
Leading with rigor, kindness, and care
“We cannot be effective scientists if we are unhappy or unhealthy outside of the lab,” says “Committed to Caring” honoree Sara Prescott.
000
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 01/04/2026
Melvyn Goodale at the MIT Consciousness Club Linking Past and Present Worlds in the Visual Control of Behaviour youtu.be/kThwjMtbe6I?... #neuroscience #conciousness
youtu.be
Melvyn Goodale - Linking Past and Present Worlds in the Visual Control of Behaviour
YouTube video by MIT Consciousness Club
0181
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 02/04/2026
A review of #autism research across our institute as we recognize World #AutismAwarenessDay: picower.mit.edu/news/autism-...
picower.mit.edu
Autism advances
Rooted in fundamental curiosity about how the brain works, Picower scientists continue to break new ground in understanding autism and devising treatment strategies
001
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 30/03/2026
🗓️Join us online April 9 when researchers from MIT, University of São Paulo and Rutgers University will present short talks on their research on Down syndrome and related conditions. Registration is open and free! picower.mit.edu/events/accel... #downsyndrome
picower.mit.edu
Accelerating Research for Down Syndrome
001
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 23/03/2026
Our spring newsletter is out now! In a dish or on a computer, brain simulations can advance basic discovery and biomedical research. Read our cover story (picower.mit.edu/news/brain-s...) and subscribe for free (picower.mit.edu/news/subscribe)! #neuroscience @earlkmiller.bsky.social
A newsletter cover uses a bottom-left to upper-right white line to divide the main image between a tissue culture made of cells and a printed circuit. Each has a nearly matching light-blue hue.
063
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 17/03/2026
New discovery! Several different anesthetics each similarly destabilize neural activity. The insight could lead to a universal anesthesia delivery system to monitor patient consciousness and dosing more effectively. picower.mit.edu/news/three-a.... #neuroscience @mitbcs.bsky.social
Doctors place a mask on the faced of a woman lying unconscious on an operating table
110
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 13/03/2026
Li-Huei Tsai, who has led The Picower Institute since 2009, will step down as director at the end of the academic year. Her decision frees her to focus on research, including her leadership of MIT’s Aging Brain Initiative and the Alana Down Syndrome Center. picower.mit.edu/news/after-1...
picower.mit.edu
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching
Tsai, who has grown the MIT neuroscience institute, will increase focus on research including Alzheimer’s disease and Down syndrome
100
Reposted by The Picower Institute for Learning and Memory at MIT
Sreeparna Pradhan @sreeparnap.bsky.social · 12/03/2026
The MIT BCS Postdoc Association is looking for a Rising Star 🌟 Showcase your work and meet folks in the department! Deadline 31st May 2026! @picowerinstitute.bsky.social
043
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 11/03/2026
Last night @wcvb5.bsky.social aired an update on local technologies to help people with Alzheimer's, including by Li-Huei Tsai's lab www.wcvb.com/article/alzh...
wcvb.com
From robots to brain games, new tools in the fight against Alzheimer’s
Technology is opening new paths for patients living with Alzheimer’s disease.
000
Reposted by The Picower Institute for Learning and Memory at MIT
BrainFacts @brainfacts.org · 05/02/2026
This social isolation helps curb the spread of disease across species, researchers found. vist.ly/4qg98
brainfacts.org
Immune and Nervous Systems Shut Down Socializing When Sick
This social isolation helps curb the spread of disease across species, researchers found.
031
Reposted by The Picower Institute for Learning and Memory at MIT
Earl K. Miller @earlkmiller.bsky.social · 25/02/2026
Is The Brain an Analog Computer? Consciousness as Dynamic Brainwave Organization | Earl Miller Mind-Body Solution podcast. youtu.be/vZ1B-MvGMgw?... #neuroscience
youtu.be
Is The Brain an Analog Computer? Consciousness as Dynamic Brainwave Organization | Earl Miller
YouTube video by Mind-Body Solution
3294
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 25/02/2026
MIT neuroscientists have found that mutations that cause Rett syndrome undermine the structural integrity of developing blood vessels. By showing that the problem derives from overexpression of a microRNA,the new study points to a potential treatment. picower.mit.edu/news/rett-sy... #neuroscience
picower.mit.edu
In Rett syndrome, leaky brain blood vessels traced to microRNA
MIT neuroscientists have found that either of two genetic mutations that cause Rett syndrome undermine the structural integrity of developing blood vessels. By showing that the problem derives from ov...
131
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 24/02/2026
Wow, that was a lot of snow! ❄ Snow much snow. But quick work by MIT Facilities Grounds Services has pushed the wall back from the doors so we'll be back to neurosciencing tomorrow! Photo by Layla Gonzalez.
The glassy entrance to the Picower Institute's building is faced by a giant snow pile yards away. In the middle are clear dry pavers.
020
The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 24/02/2026
Three new neural network-based tools enable fast, accurate alignment and annotation of images even in very wiggly subjects🪱🪼. The tools might offer a way to automate cell tracking in other imaging datasets, too. picower.mit.edu/news/worms-a... #neuroscience #AI @mitbcs.bsky.social
picower.mit.edu
As worms and jellyfish wriggle, new AI tools track their neurons
Three new neural network-based tools enable fast, accurate alignment and annotation of images even in very wiggly subjects. The tools might offer a way to automate cell tracking in other imaging datas...
140