We show that, in a genomic locus with minimal complexity, the distance between promoter and enhancer modulates the frequency of clustered transcriptional bursts. Thus, besides the nucleotide sequence,...

By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University

Microsoft Excel: 1 — Human Genetics: 0.

How intrinsically disordered regions (IDRs) shape chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We used proximity-assisted photoactivation (PAPA), a single...

Don't blame LLMs. We have always wanted slop.

Federal funding cuts have curtailed research at elite universities such as MIT, dulling America’s competitive edge globally.

The last year was marked by turmoil at science agencies and the administration’s stated desire to shrink the federal workforce.

Shirley Meng explains why her passion for decarbonizing the global economy required her to relocate

Chromatin dynamics govern search times between DNA elements. Using integrated MINFLUX imaging, Mazzocca, Narducci, Grosse-Holz and colleagues track chromatin dynamics over seven orders of magnitude in...