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Mathias Boulanger

@mathias-boulanger.bsky.social

Senior Bioinformatician / data analyst at @EMBL GeneCore - Ph.D in health biology and genomics | Former postdoc at @EMBL Krebs lab - PhD student at @igmm

Posts Replies Media

Reposted by Mathias Boulanger

Ewan Birney @ewanbirney.bsky.social · 18/08/2025

Just brilliat work by Kasit and colleagues in @arnaudkr.bsky.social's group @embl.org. This is leveraging the "everyday" length of ONT (20KB) plus exogenous modification to sort out co-occupancy between enhancers and promoters (and inter-enhancer).

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Reposted by Mathias Boulanger

Arnaud Krebs @arnaudkr.bsky.social · 18/08/2025

This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇

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Mathias Boulanger @mathias-boulanger.bsky.social · 18/08/2025

Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation www.biorxiv.org/content/10.1... @embl.org

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