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Dillingham Lab

@dillinghamlab.bsky.social
775 followers 614 following 11 posts

Studying DNA replication, repair and recombination using biochemical, biophysical and structural methods. University of Bristol, UK. ORCID ID: 0000-0002-4612-7141

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Reposted by Dillingham Lab
Malcolm White @mfwhite2.bsky.social · 25/09/2026
New from the @multidefence.bsky.social consortium: a deep dive into MANTIS defence. Thanks to @ukri.org for funding. www.biorxiv.org/content/10.6...
biorxiv.org
Dual ATPase-activated DNA hemimethylation and cleavage by the MANTIS defence system
Bacterial defence systems are diverse and form major barriers to horizontal gene transfer and bacteriophage (phage) infection. Though restriction-modification systems were the first such defences disc...
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The Dunn School, Oxford @dunnschool.bsky.social · 14/07/2026
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...
path.ox.ac.uk
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
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Michael Trakselis @trakselis.bsky.social · 14/07/2026
We are so fortunate to be able to offer a new postdoc position in the #Traklab. Please see the description below and forward on. sites.baylor.edu/trakselisgro...
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Jon Lane @jondlane.bsky.social · 11/07/2026
The SWBio PhD programme is recruiting 2 students in Engineering Biology for Autumn 2026 start. Please find available projects, host institutions & links to the application system here: www.swbio.ac.uk/programme/pr... Note: these studentships are available to HOME (UK) students ONLY.
swbio.ac.uk
Projects available – SWBiosciences Doctoral Training Partnership
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Stephen McLaughlin @lmbbiophysics.bsky.social · 29/06/2026
It will be our 10th Next Generation Biophysics Symposium @mrclmb.ac.uk on 16th September. Please join us in person or online and celebrate all things #biophysics www3.mrc-lmb.cam.ac.uk/sites/nextge...
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 26/06/2026
2026 marks the tenth edition of the Next Generation Biophysics Symposium! Registration for this year’s event, happening at the LMB on Wednesday 16th September, is open now ➡️ www3.mrc-lmb.cam.ac.uk/sites/nextge…
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Cees Dekker @ceesdekker.bsky.social · 16/06/2026
WORK: our Bionanoscience department at TU Delft is looking to hire an Assistant Professor in Biophysics of Living Systems. Apply! Deadline 30 July careers.tudelft.nl/job/Delft-As... RT=nice
careers.tudelft.nl
Assistant Professor in Biophysics of Living Systems
Assistant Professor in Biophysics of Living Systems
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Dirk Remus @dirkremus.bsky.social · 13/06/2026
If you have experience in biochemistry/cryo-EM, are interested in DNA replication, and would like to do a postdoc in New York - our lab has positions available! Just DM or email me with your CV.
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Biochemical Society @biochemsoc.bsky.social · 12/06/2026
From creating structural biology pipelines to investigating DNA mismatch repair, it's been an insightful week in Crete for our Machines on Genes conference! Congratulations to our poster prize winners: Daniel, James, Manuel and Emma for their fantastic presentations. 🧪
Daniel Ramirez Montero holding his poster prize certificate by the stage at the Biochemical Society's 94th Harden Conference: Machines on Genes.Emma Arean-Ulloa, James Provan and Manuel Osorio Valeriano holding their poster prize certificates in front of the stage at the Biochemical Society's 94th Harden Conference: Machines on Genes.
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Stephen McLaughlin @lmbbiophysics.bsky.social · 05/05/2026
Hope you can join us for our 10th Next Generation Biophysics Symposium @mrclmb.ac.uk in September. We have a fantastic speaker line up: www3.mrc-lmb.cam.ac.uk/sites/nextge...
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Marc van der Kamp @marcvanderkamp.bsky.social · 20/03/2026
Registration is open for the #CCPBioSim Annual Conference, 6-8 July, Bristol, UK! See: www.ccpbiosim.ac.uk/bristol2026 Delighted to be hosting the conference @bristoluni.bsky.social, with the theme "Biomolecular simulation across scales, for understanding and design" #compchem #compbio #biodesign
ccpbiosim.ac.uk
CCPBioSim Annual Conference
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Syma Khalid @sykhalid.bsky.social · 02/02/2026
A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends. www.jbc.org/article/S002...
jbc.org
Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope
Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative bacteria. We unco...
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Zha Lab @zhalab.bsky.social · 22/12/2025
Are you ready for 2026? Social DNAing is! See who is coming. Sign up at www.cancer.columbia.edu/research/pro...
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Charles Winterhalter @winterhalterlab.bsky.social · 23/01/2026
E. coli is the leading bacterium causing death from AMR infections worldwide. If you'd like to explore approaches to exploit the DNA damage response as alternative antimicrobial, please apply to the following PhD studentship available in my lab starting October 2026: www.findaphd.com/phds/project...
findaphd.com
Exploiting the bacterial DNA damage response as an alternative antimicrobial at Newcastle University on FindAPhD.com
PhD Project - Exploiting the bacterial DNA damage response as an alternative antimicrobial at Newcastle University, listed on FindAPhD.com
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Daniela Barillà @danielabarilla.bsky.social · 09/01/2026
Totally! 💯 Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award. If you have received,you give back to the community
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Lori Passmore @lapassmore.bsky.social · 05/01/2026
Alessandro Costa @costalaboratory.bsky.social, Dana Branzei and myself are co-organising the 2026 Machines on Genes meeting in beautiful Crete as the 94th Harden Conference hosted by @biochemsoc.bsky.social Register now - lots of opportunities for selected talks www.eventsforce.net/biochemsoc/f...
eventsforce.net
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Hasan Yardimci @hyardimci.bsky.social · 25/11/2025
We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you. Application deadline: 24 December www.crick.ac.uk/careers-stud...
crick.ac.uk
Postdoctoral Fellow - H Yardimci Lab
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Multi-Defence @multidefence.bsky.social · 14/11/2025
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity? Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4) #PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
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Dillingham Lab @dillinghamlab.bsky.social · 13/11/2025
34 fully-funded PhD studentships in the Biosciences across UK Universities in the South West (including Bristol Biochemistry!) Home and International students eligible Information and applications here www.swbio.ac.uk
swbio.ac.uk
SWBiosciences Doctoral Training Partnership
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 10/11/2025
Considering the LMB for your PhD? We’ve got over 25 projects available, covering a wide array of topics. Check them out here: www2.mrc-lmb.cam.ac.uk/students/int... Apply by 2nd DEC for Autumn 2026 admission.
Join the LMB's PhD programme!
Applications now open for October 2026
Deadline 2nd December 2025
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Malcolm White @mfwhite2.bsky.social · 10/11/2025
Thinking about your first steps to independent research? We'd love to hear from you. More details below, or contact me directly for details - reposts appreciated! www.nature.com/naturecareer...
nature.com
Biomolecular Science Fellowship Day - St Andrews, Fife (GB) job with UNIVERSITY OF ST ANDREWS | 12848597
The School of Biology at the University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candida...
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Daniela Barillà @danielabarilla.bsky.social · 09/11/2025
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects.High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
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Andrew Deans @genomestability.bsky.social · 09/11/2025
🧬 List of 2026 DNA repair and genome stability conferences, now updated. Please let me know if there is anything missing! docs.google.com/spreadsheets...
docs.google.com
DNA REPAIR/GENOME STABILITY CONFERENCES
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Steven Shaw @steven-shaw.bsky.social · 08/11/2025
Exciting PhD opportunity! Uncover the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas. Based in the Szczelkun lab in Bristol with strong collaboration with the Blower lab at NEB and opportunities to work with other amazing research groups! Link below:
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Harry Low’s Lab @lowlab.bsky.social · 29/10/2025
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
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John Innes Centre @johninnescentre.bsky.social · 08/10/2025
Applications are now OPEN for the JIF Rotation PhD Programme This prestigious 4-year #PhD programme trains graduate students in Plant and Microbial Sciences at the JIC, @thesainsburylab.bsky.social and @earlhaminst.bsky.social. 🗓️ Closing date - 13 November 2025 www.jic.ac.uk/training-car...
jic.ac.uk
Rotation biology PhDs | John Innes Centre
Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…
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TJ McCorvie @allostericstate.bsky.social · 21/10/2025
Please join us in the North East on the 5th of November as we celebrate with a one day symposium for the launch of our BBSRC funded 100 keV Tundra TEM aka the Northern Eye: nusbf.ncl.ac.uk/ccpem-tfs-ne... The symposium has been kindly sponsored by @thermofishersci.bsky.social & @ccpem.bsky.social
nusbf.ncl.ac.uk
Grand Opening of the Northern eye, a cryo-TEM in Newcastle
Grand Opening of the Northern Eye in Newcastle, a100 kV Tundra cryo-TEM in Newcastle University on Wednesday 5th November 2025
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Morgan Jones @04mjone.bsky.social · 14/10/2025
I’m really excited to share that I’ve been awarded a Wellcome Trust Career Development Award to start my own research group at Oxford University Biochemistry Department @BiochemOxford 🧬🎉
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Liam Faller @liamfaller.bsky.social · 13/10/2025
First ad for a position in my new lab at the University of Bristol! If you are looking for a fully funded PhD in cutting edge science that will be based in a supportive environment, and in a great city, check out the link below! www.findaphd.com/phds/project...
findaphd.com
Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol on FindAPhD.com
PhD Project - Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol, listed on FindAPhD.com
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Stephan Gruber @gruberlab.bsky.social · 09/10/2025
How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️. Check out the new paper: www.cell.com/molecular-ce...
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Tung Le @tunglejic.bsky.social · 03/10/2025
Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
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The Francis Crick Institute @crick.ac.uk · 07/10/2025
2026 PhD recruitment is now open. As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website: www.crick.ac.uk/careers-stud...
crick.ac.uk
PhD student recruitment
PhD recruitment information.
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Grainger Lab @graingerlab.bsky.social · 07/10/2025
Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation. www.findaphd.com/phds/?Keywor...
findaphd.com
grainger birmingham PhD Projects, Programmes & Scholarships - 3 PhDs Listed
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
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Paul Fogg @pcmfogg.bsky.social · 07/10/2025
Still a couple of days left to apply for this postdoc #job. With access to world-class facilities, you will unravel the DNA-packaging mechanisms used by #phages and the unusual #GeneTransferAgents, and explore the impact of these tiny machines on evolution, resistance, and biotech. @ukri.org #bbsrc
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Harry Low’s Lab @lowlab.bsky.social · 11/08/2025
Please RT 🙏 If you’re an early career researcher working in the fields of structural or synthetic biology wishing to start your lab then come join us at Imperial. We’re looking to support outstanding individuals for external Career Development Awards/Fellowships. www.imperial.ac.uk/media/imperi...
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Harry Low’s Lab @lowlab.bsky.social · 28/07/2025
Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏 www.imperial.ac.uk/media/imperi...
imperial.ac.uk
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Genome Damage and Stability Centre (GDSC) @gdsc-sussex.bsky.social · 21/07/2025
Sussex is the host for this year's South West Structural Biology Consortium meeting [we snuck in... !]. Looking forward to hearing talks from Universities of Bath, Bristol, Cardiff, Exeter, Portsmouth, Southampton and of course, Sussex!
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Saloni @scientificdiscovery.dev · 21/07/2025
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good! There are also little quizzes and interactives. www.ebi.ac.uk/training/onl...
ebi.ac.uk
AlphaFold - A practical guide
AlphaFold - A practical guide
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Alessandro Costa @costalaboratory.bsky.social · 21/07/2025
Less than two weeks left to apply! Postdoc positions in my lab to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists & structural biologists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...
crick.wd3.myworkdayjobs.com
Postdoctoral Fellow - Costa Lab
Salary for this Role: From £45,500 with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Costa Lab Reports to: Alessandro Costa Closing Date: 03/Aug/2025 23.59 GMT Job Desc...
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 19/07/2025
Interested in the "Crystallography Through The Decades" session at #aca2025? Take a tour of the PDB over the years at PDB-101 pdb101.rcsb.org/motm...
pdb101.rcsb.org
PDB101: Molecule of the Month: Fifty Years of Open Access to PDB Structures
The Protein Data Bank is celebrating its golden anniversary!
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John Innes Centre @johninnescentre.bsky.social · 18/07/2025
PRESS RELEASE - Major funding boost to bring world leading researchers to the John Innes Centre We have been awarded an equal share of the new £54 million Global Talent Fund, to attract and support leading researchers and their teams to relocate to the UK: www.jic.ac.uk/press-releas...
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Dillingham Lab @dillinghamlab.bsky.social · 16/07/2025
BBC News - Babies made using three people's DNA are born free of hereditary disease www.bbc.com/news/article...
bbc.com
Babies from three people's DNA prevents heriditary disease
The method was pioneered by UK scientists to overcome devastating, sometimes fatal inherited diseases.
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Stephen McLaughlin @lmbbiophysics.bsky.social · 20/06/2025
Excited for our program of speakers at Next Generation Biophysics 2025. Come join us as registration is now open either in person or online: www3.mrc-lmb.cam.ac.uk/sites/nextge...
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Alessandro Costa @costalaboratory.bsky.social · 20/06/2025
Postdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...
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Harry Low’s Lab @lowlab.bsky.social · 28/04/2025
Please RT. Post-doc opportunity alert! 💥 closing 5th May.. Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
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Richard Sever @richardsever.bsky.social · 15/04/2025
Moving obituary of David Stephens, "in many ways, the perfect academic" journals.biologists.com/jcs/article/...
journals.biologists.com
Remembering David Stephens (1971–2024)
In the autumn of 2024, David Stephens, a prominent member of the UK cell biology community and a brilliant scientist, leader and mentor, passed away. With his pragmatism and natural authority, combine...
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Malcolm White @mfwhite2.bsky.social · 31/03/2025
www.findaphd.com/phds/project... A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social
findaphd.com
Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews on FindAPhD.com
PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 31/03/2025
How do SMC complexes capture DNA? 🧪 Led by Frank Bürmann, Jan Löwe’s & Mark Dillingham’s groups have identified the directional loading mechanism the bacterial SMC complex MukBEF uses to capture & ingest DNA, & found a phage inhibitor to this pathway. Read more: tinyurl.com/4s8nrrkk #LMBResearch
Schematic illustrating the structural changes undergone by MukBEF SMC complex during DNA capture and ingestion.
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RepState Project @repstateeu.bsky.social · 03/02/2025
Hello Bluesky! We are a research network of 13 PhD researchers exploring DNA repair mechanisms 🧬 🏛️ Partnering with research institutions across Europe 💡 Fostering collaborations between academia and industry to drive innovation #RepState #DNADamage #DNARepair #ScientificResearch #EUResearch
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Harry Low’s Lab @lowlab.bsky.social · 28/03/2025
Please RT. Post-doc opportunity alert! 💥 Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
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