Small regulatory RNAs can act on target mRNAs to control their translation and stability. Here, the authors present evidence that this riboregulation can potentially regulate by pairing to a target si...

Phylogenetic and biochemical analyses show a diversity of components of the DNA replication machinery in different Asgard archaea that contributed to the eukaryotic DNA replication machinery.

imageimageCtf18-RFC is a dedicated leading-strand replication clamp loader, with RFC unable to fulfil this role. This study provides a mechanistic basis as to why this is the case and reveals unique f...