Communications Chemistry - Differential detection of tau aggregation species using a small molecule probe for cell-based drug screening

Getting a grant funded starts with knowing what the panel wants. Louise Serpell shares advice from the review board, summary to interview.

Programmed −1 ribosomal frameshifting (PRF) is a translational control mechanism used by RNA viruses to regulate the relative abundance of proteins en…

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Detergent-induced membrane solubilization is important for several biotechnological applications including membrane protein isolation, cell lysis and virus inactivation. The thermodynamic details of t...

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Detergent-induced membrane solubilization is important for several biotechnological applications including membrane protein isolation, cell lysis and virus inactivation. The thermodynamic details of t...

Single-molecule Förster resonance energy transfer (smFRET) studies of highly structured RNA molecules are often frustrated by issues with efficient dye conjugation. Here, we develop a DNA scaffold-bas...

Dynamic DNA machines exploit the specificity of base pairing and/or sensitivity to the local environment to control the reversible switching of DNA constructs between conformational states. One such e...

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The recent development of drugs able to mitigate neurodegenerative diseases has created an urgent need for novel diagnostics. Although biomarker detection directly in patients' blood is now possible, ...

Help Steven Quinn raise money to support Alzheimer's Research UK

Alzheimer’s disease (AD) represents one of the most pressing healthcare challenges of the 21st century. As a leading cause of dementia, AD impacts over 55 million people worldwide, with this number pr...

PhD Project - Probing the Function of RNA Structural Elements in the FMDV Genome using Biophysical and Genetic Approaches at The Pirbright Institute, listed on FindAPhD.com