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Rodrigues Lab

@crodrigueslab.bsky.social
200 followers 156 following 16 posts

Understanding how bacteria develop into one of the toughest cell types on Earth - Spores Principal Investigator | Reader www.rodrigueslab.com

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Susan Schlimpert @s-lab.bsky.social · 25/08/2026
It is happening, and registration is open for the EMBO Workshop: Bacterial and archaeal cell division: diverse mechanisms and models. 20–23 April 2027 | Barga, Italy. Come and join us @awehenkel.bsky.social, @seamusholden.bsky.social, @s-lab.bsky.social ! Deadline: Jan 6, 2027. #Bacdiv27
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EMBO @embo.org · 24/08/2026
Sign up now for the EMBO Workshop "Bacterial and archaeal #CellDivision: Diverse mechanisms and models" in Barga (Lucca), Italy, 20–23 April 2027. Deadline: 6 January 2027 meetings.embo.org/event/27-cell-div… #EMBObacDiv27 #genetics #biochemistry #StructuralBiology #EMBOevents 🧪
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Cristina Landeta-Escamilla @cris-s.bsky.social · 16/08/2026
Our virus story @growkudos.bsky.social www.growkudos.com/publications...
growkudos.com
Giant viruses carry their own "chemical toolkit" to change the fats in the cells they infect
We found that giant viruses encode a key enzyme (VKOR) usually found in cells to perform redox reactions. This enzyme is part of a larger module that can modify membrane lipids. These "mini pathway" t...
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Saganism @sagan.bsky.social · 14/08/2026
41 years ago, Carl Sagan gave a clear and elegant explanation of the science behind global warming.
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Rodrigues Lab @crodrigueslab.bsky.social · 14/08/2026
Excited to share our study focused on the honeybee pathogen, Paenibacillus larvae, published in @plos.org Pathogens. Thanks to our collaborators David Chandler, @xavierdidelot.bsky.social and Matej Medvecky. Funded by @bbka.org.uk and Bee Disease Insurance. journals.plos.org/plospathogen...
journals.plos.org
Comparative genomics and phenotypic divergence of ERIC I and ERIC II genotypes of Paenibacillus larvae, the causative agent of American Foulbrood disease
Author summary Honeybees (Apis mellifera) are essential pollinators that support global agriculture and ecosystem stability. American foulbrood (AFB) is a highly destructive disease of honeybee larvae...
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Ran Blekhman @blekhman.bsky.social · 09/08/2026
Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9zv3rj...
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Rodrigues Lab @crodrigueslab.bsky.social · 28/07/2026
Looks like the nanotubes are back! 🤔
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Rodrigues Lab @crodrigueslab.bsky.social · 28/07/2026
Paper accepted in PLOS Pathogens! More on this work soon! 🥳
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 24/07/2026
A self-organized geometry sensing oscillator spatially regulates cell division in archaea www.biorxiv.org/content/10.64898/20…
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STCmicrobeblog @stcmicrobeblog.bsky.social · 16/07/2026
«The Fellowship of the Z Ring» the next chapter... 👇 #Archaea #ArchaeaSky #MicroSky
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Rodrigues Lab @crodrigueslab.bsky.social · 15/07/2026
Checkout out the latest from our lab. One of two papers published by PhD student, Behzad Dehghani who recently completed their PhD. We identify CprV as a "safeguard" protein that helps protect cellular compartmentalisation during bacterial spore formation. www.nature.com/articles/s42...
nature.com
A safeguarding factor monitors septal pore stability to secure compartmentalization during sporulation in Bacillus subtilis - Communications Biology
Identification of CprV during bacterial sporulation reveals insight into how developing cells monitor compartmental integrity during cellular remodelling and differentiation.
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Gregor Weiss @weiss-lab.bsky.social · 10/07/2026
Some bacteria do not live as individuals. They build multicellular filaments and connect neighboring cells through tiny cell-cell junctions. Cyanobacteria are among the most beautiful examples 😍 In our new paper, we reveal first molecuar insights on the cyanobacterial septal junction architecture 🧵
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 10/07/2026
Assembly of the essential SpoIVA coat protein at the surface of developing bacterial spores www.biorxiv.org/content/10.64898/20…
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 09/07/2026
SpoIVA contributes to efficient engulfment through a cytoskeletal-like mechanism during Bacillus subtilis sporulation www.biorxiv.org/content/10.64898/20…
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Cell Press @cellpress.bsky.social · 02/07/2026
How psychological stress alters gut microbes and ages blood stem cells in mice. Learn more in Cell Stem Cell: www.cell.com/cell-stem-ce... Linjia Jiang, Meng Zhao & colleagues @cp-cellstemcell.bsky.social
first page of Cell Stem Cell article "Psychological stress drives aging-like hematopoietic stem cell dysfunction through a brain–gut–bone marrow axis"
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Ákos T Kovács @evolvedbiofilm.bsky.social · 01/07/2026
Directed Evolution of Plant-Associated Bacteria Enhances Plant Holobiont Stress Tolerance [Bacillus subtilis] in Plant Cell Environment onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Directed Evolution of Plant‐Associated Bacteria Enhances Plant Holobiont Stress Tolerance
Directed evolution of plant-associated bacteria enhanced their metabolite production and functional traits. Inoculation of coriander (Coriandrum sativum) with the evolved strains improved heavy metal...
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Joachim Goedhart @joachimgoedhart.bsky.social · 01/07/2026
A High-Affinity Nanobody Recognizing mNeonGreen Enables Versatile Biochemical, Cellular, and in vivo Applications. by Steffen Frey and team: www.biorxiv.org/content/10.6...
mNeonGreen Selector: a pulldown resin for mNeonGreen-fusion proteins. (A) Sketch of mNG
Selector binding mNG fusion proteins. (B, C) Immunoprecipitation from E.coli lysate in the presence (B) or
absence (C) of target protein (mNG-Halo fusion, arrowhead). Proteins were eluted in boiling SDS sample
buffer. mNG Selector enables highly specific one-step capture of mNG-tagged proteins. (D) Binding assay to
evaluate the cross-reactivity of the mNG Selector to other recombinant fluorescent proteins. Shown is a figure
of the equilibrium bound fraction of each indicated fluorescent protein prior to buffer washing. (E)
Compatibility of mNG Selector to various reagents applied during binding (top panel) or during washing steps
(lower panel). mNG fluorescence is lost in the presence of 2 M Gua-HCl. The symbols below each row indicate
binding efficiency: ++: strong binding, + binding, -: no binding
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 23/06/2026
Our Dept of Microbiology & Immunology @Geisel School of Medicine @Dartmouth has an opening for an Assistant Professor. Looking for programs bridging multiple areas in Micro & Immuno. A great place to be! Programs: www.M2P2.org www.dartmouthbiofilm.org Job ad: apply.interfolio.com/187637
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Christophe 🔬 Leterrier @christlet.bsky.social · 15/06/2026
A ratiometric membrane tension probe based on a non-conducing TRAAK channel bearing a split HaloTag. Compares well with Flipper-TR (and no need for lifetime imaging capacity): www.biorxiv.org/content/10.6...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 12/06/2026
Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity @natmicrobiol.nature.com from Michael Laub & Abel Garcia-Pino www.nature.com/articles/s41...
nature.com
Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity - Nature Microbiology
The activation of an antiphage defence system relies on host factors targeted by phages, a mechanism analogous to the way that eukaryotic innate immune systems detect pathogen-induced perturbations of...
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Sonja-Verena Albers @archaellum.bsky.social · 20/05/2026
New preprint! Cell division has to happen at the right place but how Archaea pick that place is unknown. We now identified a three-protein system, Dip, that positions the divisome at midcell in H. volcanii and is broadly conserved across Archaea. A thread 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
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British Beekeepers Association @bbka.org.uk · 05/05/2026
The National Bee Unit's BeeBase website is a vital resource for beekeepers and honey bee health. The resources section contains a wealth of valuable information on pests and diseases and other topics Registering on BeeBase is free and highly recommended for all beekeepers www.nationalbeeunit.com
nationalbeeunit.com
Home » APHA - National Bee Unit - BeeBase
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AmirAli Toghani @amiralito.bsky.social · 05/05/2026
Protein structure prediction changed biology. Protein assembly discovery is next. We present SNI (Structural Novelty Index), a scalable framework for finding new protein complexes. We used it to uncover an unexpected resistosome assembly: 11-mer. 🧵👇🏻 biorxiv.org/content/10.6...
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Megan Sorensen @messorensen.bsky.social · 30/04/2026
Interested in working on the evolution of photosynthetic endosymbioses? Come join us! I have 2 open positions in my new group @cemess.bsky.social in Vienna 3yr postdoc info: tinyurl.com/4emkjpn4 4yr PhD info: tinyurl.com/mtxmsjpy Apply by 1st June! Please share/repost #Protists #Symbiosis #PhD
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Charles Winterhalter @winterhalterlab.bsky.social · 29/04/2026
What are the genetic and molecular determinants underpinning the repair of bidirectional replication fork collapse in bacteria? PhD position open in my lab in collaboration with the brilliant @heathmurraylab.bsky.social. Please share and contact me if interested: www.findaphd.com/phds/project...
findaphd.com
Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University on FindAPhD.com
PhD Project - Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University, listed on FindAPhD.com
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Adrià Sogues @adriasogues.bsky.social · 27/04/2026
This one deserves it🤩! We used cryo‑EM to identify a new “sporesilk” in Bacillus thuringiensis. The fiber, called A‑ENA, forms an incredibly stable covalent network that increases virulence by keeping the toxic payload and spores in a biofilm-like structure. www.nature.com/articles/s41...
nature.com
Auto-crosslinking sporesilk fibers promote endospore and Cry toxin clustering - Nature Communications
Authors reveal that protein nanofibrils govern assembly of bacterial spores and extrasporal toxins into insecticidal aggregates. Spores and parasporal bodies are incased in a “sporesilk” matrix that d...
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Freya Harrison @friendlymicrobe.bsky.social · 22/04/2026
And a 7th post @warwicklifesci.bsky.social! This one assistant/associate prof in quantitative, systems & engineering biology: warwick-careers.tal.net/vx/lang-en-G...
warwick-careers.tal.net
Associate Professor or Assistant Professor in Quantitative, Systems and Engineering Biology (111546-0426) - University of Warwick
Title: Associate Professor or Assistant Professor in Quantitative, Systems and Engineering Biology (111546-0426). Application Deadline: . Position Type: Permanent
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Freya Harrison @friendlymicrobe.bsky.social · 20/04/2026
My super department @warwicklifesci.bsky.social is hiring 6 assistant profs in the wake of recent retirements. We're looking for people in microbiology/infection, cellular disease / immunity; environmental biology; and plant/crop science. #MicroSky warwick-careers.tal.net/vx/lang-en-G...
warwick-careers.tal.net
Assistant Professor x6 (111522-0426) - University of Warwick
Title: Assistant Professor x6 (111522-0426). Application Deadline: . Position Type: Permanent
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Stella Hurtley @smhsci.bsky.social · 17/04/2026
Out now in @science.org Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape | Science www.science.org/doi/10.1126/...
science.org
Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape
Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In m...
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Magnus Kjærgaard @proteinmagnus.bsky.social · 26/03/2026
Why do intrinsically disordered proteins appear larger than they are in SDS-PAGE? We investigate how sequence properties affect SDS-PAGE mobility using synthetic IDRs. Conclusion: We need to consider both SDS binding and the compaction of protein-SDS complexes. www.biorxiv.org/content/10.6...
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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 17/03/2026
AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk
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Addgene @addgene.bsky.social · 20/02/2026
Find the hot-off-the-press plasmids here! www.addgene.org/browse/artic...
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Nature @nature.com · 10/03/2026
For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell go.nature.com/4lrAulM
go.nature.com
'Virtual cell' captures most-basic process of life: bacterial division
Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.
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Nick Polizzi @nickpolizzi.bsky.social · 11/03/2026
Our paper with @sokrypton.org using AlphaFold2 to predict small-molecule binding sites in proteins is now out in Nature Methods! 🧵 rdcu.be/e7SnX www.nature.com/articles/s41...
rdcu.be
AF2BIND: predicting small-molecule binding sites using the pair representation of AlphaFold2
Nature Methods - AF2BIND is a logistic regression model trained on AlphaFold2 pair features to predict small-molecule binding-site residues in proteins, without multiple sequence alignments,...
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Jean-Yves Tinevez @jytinevez.bsky.social · 09/03/2026
Let's get ready for a full month of training in image analysis in @pasteur.fr , this summer! Are you interested in learning how to do bioimage analysis? For light microscopy? for cryo-EM? And for cellular cryo-EM? Stay tuned, Pasteur offers access to THREE courses, this June. 👇🎓
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Ákos T Kovács @evolvedbiofilm.bsky.social · 09/03/2026
The registration is now open for BACELL meeting on 8-9 June 2026 at University of Malaga, Spain. Register and submit abstract for oral or poster presentation: bacell2026.eu Deadline for abstract submission: 31 March 2026 Registration deadline: 15 May 2026 Organizer @diegromero.bsky.social
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Biology-UNIGE @biology-unige.bsky.social · 05/03/2026
✨ New postdoctoral opportunity in #cell biology at UNIGE! @sophiemartinlab.bsky.social is looking for a postdoc to study cell–cell fusion. Spread the word and see details below 👇@mocel.bsky.social @sciencesunige.bsky.socia
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Freya Harrison @friendlymicrobe.bsky.social · 05/03/2026
#MicroSky
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Ákos T Kovács @evolvedbiofilm.bsky.social · 03/03/2026
Save the date for the next International Conference on Gram-Positive Bacteria which will take place between 29 June–2 July 2027. The organizers (@annadragos.bsky.social, @polonca32.bsky.social, and Ines Mandic-Mulec) look forward to welcoming you to Ljubljana, Slovenia
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Ákos T Kovács @evolvedbiofilm.bsky.social · 26/02/2026
Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social Application deadline on 15 March 2026 👇 careers.universiteitleiden.nl/job/Assistan...
careers.universiteitleiden.nl
Assistant/Associate/Full Professor Computational Biology
Assistant/Associate/Full Professor Computational Biology
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Waggoner Lab @labwaggoner.bsky.social · 26/02/2026
SNIPE is a widespread bacterial defence system that exploits the spatial organization of phage genome injection to specifically target viral DNA, distinguishing self from non-self in prokaryotic immune systems @nature.com @mitpress.bsky.social www.nature.com/articles/s41...
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BejaLabTechnion @bejalab.bsky.social · 25/02/2026
Convergent MurJ flippase inhibition by phage lysis proteins www.nature.com/articles/s41...
nature.com
Convergent MurJ flippase inhibition by phage lysis proteins - Nature
A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial devel...
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microbingle.bsky.social @microbingle.bsky.social · 22/02/2026
The origins of agar www.asimov.press/p/agar
asimov.press
The Origins of Agar
First introduced into laboratories in 1881, agar remains indispensable as a culture medium.
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 17/02/2026
PhD & Postdoc Positions at the Dept of Microbial Population Biology of the MPI for Evolutionary Biology (Plön, Germany) to work on jumbo phages & HGT of genomic islands. An amazing research team led by the one and only Paul Rainey, one of the most hard-core evolutionary micro/biologists of our time!
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PLOS @plos.org · 11/02/2026
In recognition of International Day of Women and Girls in Science, @plosone.org brings together perspectives from Section Editors and an insightful conversation with @clairebrockett.bsky.social from @sheffielduni.bsky.social on why inclusion matters ⬇️ #IDWGS2026 #WomenInScience
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British Beekeepers Association @bbka.org.uk · 04/02/2026
The NUBee lab @Newcastle University have an exciting, fully funded opportunity to study Varroa, a major driver of honey bee colony losses. The PhD complements ongoing work. For more info (lnkd.in/eXKTNFcN) or contact Prof. Giles Budge.
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Wiep Klaas Smits (ExpBac/CMAT) @smitslab.bsky.social · 31/01/2026
Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication url: academic.oup.com/nar/article/...
academic.oup.com
Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication
Abstract. Bidirectional replication is a conserved principle requiring coordinated translocation of the two replicative helicases loaded at the origin. In
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Nico Rascovan @nrascovan.bsky.social · 27/01/2026
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
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Rodrigues Lab @crodrigueslab.bsky.social · 27/01/2026
Check out these tools to detect co-evolution in protein-protein interactions developed by postdoc @chrislbgraham.bsky.social Very useful as a hypothesis generator, complementing protein interaction prediction from Alphafold. www.biorxiv.org/content/10.6...
biorxiv.org
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anna brogan @apbrogan.bsky.social · 13/12/2025
Fer’s tour de force in B. anthracis is out! Fer got Tn-seq running, built an ordered knockout library, defined all essential sporulation genes, and found a peptidoglycan deacetylase inhibitor critical for engulfment. Including our first one-by-all Alphafold screen! journals.plos.org/plosbiology/...
journals.plos.org
Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis
How good is Bacillus subtilis as a model for the spore-forming pathogen Bacillus anthracis? Using high throughput genetics to identify B. anthracis sporulation genes and cytological analysis of the mu...
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