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Freya Harrison

@friendlymicrobe.bsky.social
3.4K followers 936 following 5.6K posts

Reader (Associate Professor) in Microbiology at the University of Warwick, UK. Biofilm, chronic infection and ancientbiotics. www.youtube.com/@BreakingBiofilm

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Freya Harrison @friendlymicrobe.bsky.social · 8h
Thank you to the Dermasphere podcast for discussing some of our work on the antibacterial activity of Bald's eyesalve #Ancientbiotics #MicroSky #biofilm podcasts.apple.com/us/podcast/1...
podcasts.apple.com
193. SCoRCH syndrome to TMP/SMX - An ancient remedy ("Bald's eyesalve") for biofilms - Leg-length discrepancy in CMTC - GLP-1s reduce the risk of psoriasis and HS
Podcast Episode · Dermasphere - The Dermatology Podcast · September 28 · 41m
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Freya Harrison @friendlymicrobe.bsky.social · 8h
This will be a brilliant post with a super team #MicroSky
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Dr Vanessa @hpsvanessa.bsky.social · 28/09/2026
Ooop www.science.org/content/arti...
science.org
Ancient sheep virus found hiding in medieval parchment
Newly recovered sheeppox sequences reveal when and how the virus emerged
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Kate Baker @ksbakes.bsky.social · 25/09/2026
We have an open Assistant/Associate Professor position in Pathogen Biology at the Department of Genetics - come and join us! 🦠 🧫 🧬https://www.cam.ac.uk/jobs/assistantassociate-professor-in-pathogen-genetics-pc51175
cam.ac.uk
Assistant/Associate Professor in Pathogen Genetics
Applications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu...
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Freya Harrison @friendlymicrobe.bsky.social · 25/09/2026
What‘s the biggest, most exciting or nagging unanswered question in biology? What do you really, really wish we knew the answer to? I’m crowdsourcing responses to these Qs for my welcome talk to new Biology undergrads next week. I’d love to know your thoughts - thank you in advance!
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Dr Vanessa @hpsvanessa.bsky.social · 25/09/2026
Cannot tell you how much I hate this & how ashamed & angry I am that @ukri.org have taken this step. We KNOW this sort of gAI is socially biased, we KNOW it favours slopAI output over human-written. Our research landscape is falling apart due to underfunding, & they do this? it's *appalling*
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Freya Harrison @friendlymicrobe.bsky.social · 24/09/2026
I helped a little with this cool study of molecules inspired by hipposudoric acid - one of the components of the red "sweat" that hippos secrete from their skin. Part of Munib Uddin's PhD with @moleculesunlimited.bsky.social onlinelibrary.wiley.com/doi/10.1002/... #MicroSky
onlinelibrary.wiley.com
The Preparation of Novel Fluorenes Inspired by Hipposudoric Acid
In this research we report on the design and synthesis of a series of fluorene-based derivatives loosely inspired by the tricyclic framework of hipposudoric acid. Preparation of sixteen novel N-alkyl....
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Freya Harrison @friendlymicrobe.bsky.social · 24/09/2026
I was wondering this - 15ish years ago I was asked to give out awards at my old school, and there were kids doing HNCs alongside GCSES. What’s better/different about the new GCSEs? Is this GNVQs again, or something sustainable?
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Ellie Jameson @elliejameson.bsky.social · 22/09/2026
MScRes bursary of £2000 available at Bangor University to study Bacteriophages as natural biocontrols for plant pathogens. Deadline is 19th October. Please contact me for more details #PhageSky #MicroSky
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Freya Harrison @friendlymicrobe.bsky.social · 22/09/2026
Excellent lab news - congratulations to @kadeayomikun.bsky.social, who has won a Warwick PATHWAY fellowship to stay on for several months after handing in his PhD and develop publications & funding applications 🥳
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Chris Millard @chrismillard83.bsky.social · 21/09/2026
“Universities have managed staff costs significantly below inflation,[between 2016-17 and 2023-24] increasing only 14% compared to the 41.2% increase in RPIX [measure of inflation]” Substantial real terms pay cut, which continues a trend existing years before that…
gov.uk
Cost of undergraduate provision and qualifications in England
A study of the full economic cost of providing undergraduate-level higher education and other qualifications in England.
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Annalee @flowerhorne.com · 19/09/2026
This is why I think it's so important to push back against the personification of LLMs. If a person shoots someone while wearing a hand puppet, they can't claim the hand puppet did the murder.
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Freya Harrison @friendlymicrobe.bsky.social · 16/09/2026
“The #phage space is developing very rapidly in the UK, and it’s an exciting time to be a part of it.” #MicroSky
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Will Ratcliff @wcratcliff.bsky.social · 15/09/2026
1/17 Submissions are now open for the 2027 Microbial Population Biology GRC! We expect this meeting to be extraordinarily oversubscribed. If you want to come, time is of the essence--apply ASAP! June 27–July 2 • Andover, NH www.grc.org/microbial-po...
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merritt @merrittk.com · 15/09/2026
god, i was born in the wrong era. imagine being around in the Cambrian period. you could just evolve something simple like shell or legs that nobody had thought of before and coast on that your whole life
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Microbiology Society @microbiologysociety.org · 15/09/2026
There’s still time to join us at our Publishing Fundamentals webinar—An Introduction to Peer Review on 16 September! Register now to secure your spot: microb.io/4wJUeEY
microb.io
Publishing Fundamentals – An Introduction to Peer Review
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Michael Baym @baym.lol · 13/09/2026
Ten years ago Tami, Roy, and I released a movie we made of antibiotic resistance evolving in real time. I thought maybe a couple thousand people tops would see it. I couldn't have imagined it would be seen millions of times, and be taught from middle school through the graduate level worldwide
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Microbiology Society @microbiologysociety.org · 10/09/2026
Join us during #PeerReviewWeek for a Publishing Fundamentals webinar dedicated to the peer review process. This event will take place on 16 September and is free for members; for non-members: £10. Register here: microb.io/4wJUeEY
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David Sünderhauf @davvi36.bsky.social · 10/09/2026
Please share! We are looking for a PhD student excited about gene transfer, and tackling Antimicrobial Resistance in Klebsiella pneumoniae. 🧬 More details & applications on funder website by 21st Oct 👇🏻 gw4biomed.ac.uk/developing-c...
gw4biomed.ac.uk
Developing CRISPR-Cas antimicrobials to tackle antibiotic resistance spread in Klebsiella pneumoniae - GW4 BioMed MRC DTP
Project Code IIAR27Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance (AMR) poses a major thre...
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Harmit Singh Malik @harmitmalik.bsky.social · 08/09/2026
So (if I understand this correctly), the way AI (companies) will "solve" all the major problems in maths, biology, and medicine in the next 5 years will be by stealing and building on the ideas of researchers naive enough to think their chats with AI companies would be private.
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Rafal Mostowy @rafalmostowy.bsky.social · 04/09/2026
🧬 Postdoc ad is now live: evolutionary genomics of Klebsiella pneumoniae phages. How do prophage depolymerases vs SGNH-esterases shape phage host range? Krakow, Poland. Deadline 21 Sept: mostowylab.com/job-postdoc-...
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Prof Jenny Rohn @jennyrohn.bsky.social · 04/09/2026
Thrilled our latest paper out @natureportfolio.nature.com Nature Comms, lead author @microberamon.bsky.social, who developed P-FLO, a urine-flowing human micro-bladder model in collab with Oxford & Leicester to understand #UTI biology & treatment failure 1/4 #UTISky www.nature.com/articles/s41...
nature.com
Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli - Nature Communications
Maset et al. show that bladder conditions strongly influence how urinary tract infections respond to antibiotics and bacteriophages, highlighting the need for more realistic lab models to improve diag...
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Sky Marchini @sky.skymarchini.net · 31/08/2026
At this point, it might be easier to make a list of Dan Ariely papers that do not use suspect data 
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Freya Harrison @friendlymicrobe.bsky.social · 03/09/2026
It's taken 12 years and a lot of work from many fantastic people, but we have published an analysis of how our reconstruction of Bald's eyesalve kills bacteria. This was driven by @tosinorababa.bsky.social & Jess Furner-Pardoe through their PhD work #MicroSky journals.asm.org/doi/10.1128/... [1/n]
Jess in the lab, holding an onion and a garlic bulb and talking; Tosin in the lab holding a petri dish and inspecting it; two glass bottles labelled "eyesalve 33/6/14"
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Freya Harrison @friendlymicrobe.bsky.social · 02/09/2026
@rachelmwheatley.bsky.social and I really enjoyed putting together a special issue of Essays in Biochemistry on the social lives of bacteria. All the papers are now out, and here's our editorial :D @biochemsoc.bsky.social #MicroSky portlandpress.com/essaysbioche...
The journal cover, showing a CLASI-FISH image of a structured bacterial community.
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Freya Harrison @friendlymicrobe.bsky.social · 01/09/2026
The use of Galleria mellonella to study microbial interactions, immune responses, & substrate interactions - super, comprehensive review from Evgenia Maslova, Ciaram Staber & @ronanmccarthy.bsky.social portlandpress.com/essaysbioche... #MicroSky
Schematic representation of G. mellonella applications for investigating interbacterial interactions
The upper half (A) of the figure depicts experimental methods in which bacteria are introduced to G. mellonella larvae. These include force-feeding, injection, and burn models. The lower half (B) shows example interactions described in the literature within the G. mellonella model, including antagonistic, competitive, and cooperative co-infection outcomes.
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Freya Harrison @friendlymicrobe.bsky.social · 01/09/2026
The social lives of bacteria as revealed through CLASI-FISH - thank you @jmarkwelch.bsky.social for this lovely review, covering the structure of bacterial communities in the human mouth, mouse gut and associated with kelp portlandpress.com/essaysbioche... #MicroSky
Bacteria in a cross-section of the mouse colon. The colonic epithelium (gray) is at right and at the bottom of the image; bacterial cells appear as colored dots, and food particles appear bright yellow. Some regions are rich in Bacteroides spp.; others have all five labeled cell types, but in all regions, bacteria are mixed.
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Freya Harrison @friendlymicrobe.bsky.social · 30/08/2026
Great piece from Marvin Whiteley. But it can be impossible or near-impossible to access the samples needed to benchmark models properly. I spent over a decade trying and failing to source resected CF lung, and we’re in year five of trying to access another sample type for one of our projects.
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Prof Jenny Rohn @jennyrohn.bsky.social · 29/08/2026
Cool study – #Mtb is notoriously slow growing, but inside macrophages, a subpopulation replicates fast and in doing so, actually evade #antibiotics better than the slow-growers - which is counter-intuitive (multiple theories discussed) #MicroSky #Tuberculosis #Tb www.nature.com/articles/s41...
nature.com
Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment - Nature Communications
The slow growth displayed by Mycobacterium tuberculosis has been historically associated with pathogen’s persistence and drug tolerance. Unexpectedly, here the authors identify a rare subpopulation of...
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Freya Harrison @friendlymicrobe.bsky.social · 30/08/2026
The ten artists I’ve enjoyed seeing live the most, in no particular order and from various phases of life: Blind Guardian VNV Nation Rachel Stamp Apocalyptica AntiProduct Public Service Broadcasting Sisters of Mercy Manic Street Preachers Epica Pulp
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Freya Harrison @friendlymicrobe.bsky.social · 23/08/2026
The possibility that accidental or unofficial releases of big cats led to self-sustaining populations in the UK countryside has been contentious. @warwicklifesci.bsky.social’s Robin Allaby is one of the people who’s been assessing the evidence, using DNA: www.discoverwildlife.com/animal-facts...
discoverwildlife.com
Black leopards are quietly thriving in the British countryside – here’s the whole incredible story | Discover Wildlife
Sightings and DNA tests suggest that large cats such as black leopards are quietly naturalising in Britain. Here’s the whole story.
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Mark A. Hanson @hansonmark.bsky.social · 14/08/2026
HIRING MICROBIOLOGIST: effective start asap! The PDRA/PDRF (per xp) will investigate the interactions of bumblebee antimicrobial peptides (AMPs) with the gut microbiota & more. Our work has shown AMPs have striking specificity for ecological microbes. careers.exeter.ac.uk/vacancies/13... 1/2
careers.exeter.ac.uk
Postdoctoral Researcher Associate or Fellow in Cornwall | University of Exeter
View details and apply for this Postdoctoral Researcher Associate or Fellow vacancy in Cornwall. Postdoctoral Research Associate / Fellow This job is part of an Advanced Research + Inventio...
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Freya Harrison @friendlymicrobe.bsky.social · 15/08/2026
Whatever Arday and his employers did or didn’t do, the person pushing the story is an open white supremacist (full video available in the linked thread).
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Freya Harrison @friendlymicrobe.bsky.social · 13/08/2026
Looking forward to reading this! #MicroSky
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Freya Harrison @friendlymicrobe.bsky.social · 13/08/2026
We have some impressive undergrad students at @uni-of-warwick.bsky.social @warwicklifesci.bsky.social 💜 Access, equity, and ambition: rethinking early careers in the life sciences portlandpress.com/biochemist/a...
portlandpress.com
Access, equity, and ambition: rethinking early careers in the life sciences
Abstract. For many students eager to pursue a career within the life sciences, the transition from education to employment is marked by uncertainty and fragmentation. This comes as a result of a lack ...
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Richard Sever @richardsever.bsky.social · 13/08/2026
bioRxiv/medRxiv have been dealing with endless bot attacks recently (plus usual DDOS stuff, etc). Tricky to address without impacting genuine users - many of you affected. Apologies. We're working with our hosting service on solutions & think we're getting there [he shouts in his Red Queen costume].
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Freya Harrison @friendlymicrobe.bsky.social · 12/08/2026
Preprint from @tosinorababa.bsky.social and a crack team he assembled to explore the mechanism of action of tEDTA against P. aeruginosa #MicroSky
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 12/08/2026
Excited to share this perspective article from my group - how can the interactions between microbes shape the spread of antibiotic resistance mutations? Thank you @microbiologysociety.org for inviting us to submit this 🦠 www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Microbial interactions as key players shaping the emergence and spread of de novo resistance mutations
Antibiotic resistance and the microbiome are two of the most prominent and highly active research areas currently in microbiology. However, these studies are commonly siloed. Research into antibiotic ...
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Freya Harrison @friendlymicrobe.bsky.social · 12/08/2026
Exploring the gaps & opportunities for development of an #AMR #AntiobioticResistance educational package for higher education: super to see this preprint from the AMRED group, including my PhD student @c-cornbill.bsky.social #MicroSky www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Exploring the gaps and opportunities for development of an AMR educational package for higher education
Antimicrobial resistance (AMR) is a complex and rapidly evolving global health challenge that requires well-trained professionals within a One Health framework. However, AMR education remains fragment...
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Katrina Ray @heykatray.bsky.social · 11/08/2026
#NoHep #gastrosky #microsky www.bbc.co.uk/news/article...
bbc.co.uk
England set to be one of the first countries to eliminate hepatitis C
England is on track to become one of the first countries in the world to eliminate hepatitis C, a dangerous virus that attacks the liver, figures show.
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Freya Harrison @friendlymicrobe.bsky.social · 11/08/2026
How do social interactions in plant microbiomes shape host health? What would a rationally-designed growth-promoting consortium look like? Thanks @carmen-escudero.bsky.social, Andrzej Tkacz, Marta Albareda & Carmen Sánchez-Cañizares for this review #MicroSky portlandpress.com/essaysbioche...
portlandpress.com
It takes a village: how plant-associated bacterial communities socialise to shape plant growth and health
Abstract. Plants outsource many functions to an associated microbiome, an ‘outside gut’ composed of socially interacting bacterial communities that support plant growth and health. These dynamic and d...
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Freya Harrison @friendlymicrobe.bsky.social · 11/08/2026
It’s not just B-DNA in #biofilm matrices - imaging approaches reveal diverse non-canonical DNA structures, and extracellular RNAs too. Thanks Gabriel Minero, Freja Sillesen & Rikke Meyer for contributing this review to Essays in Biochemistry #MicroSky portlandpress.com/essaysbioche...
portlandpress.com
Imaging nucleic acids in biofilms
Abstract. Extracellular nucleic acids (eNA) are ubiquitous components of bacterial biofilms, contributing to structural integrity, antimicrobial resistance, and immune evasion. While traditionally vie...
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Freya Harrison @friendlymicrobe.bsky.social · 11/08/2026
How do phages maintain or increase the diversity of plant-associated microbiomes? Thanks Renée Smith & @dholtappels.bsky.social for contributing this review to Essays in Biochem #MicroSky portlandpress.com/essaysbioche... 
Phages impact microbial communities from individual interactions to ecosystem-level functions. At the individual level (top, individual host represented by the dark blue color), phages infect single bacterial hosts, resulting in co-evolutionary arms races and the dispersal of genetic information through phage-mediated HGT. At the population level (closely related host bacteria as represented by various blue shades), phages and their bacterial hosts are intertwined with predator-prey dynamics and KtW dynamics, which support microbiome diversity and community structure effects. By influencing bacteria at the individual and population levels, phageomes are hypothesized to play important roles at the ecosystem level (including distantly related non-host bacteria, as represented by different colors and morphologies) in both function and resilience 
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Freya Harrison @friendlymicrobe.bsky.social · 11/08/2026
Invasive plasmids as ecosystem engineers: how can we understand & harness conjugative plasmids as agents of microbiome functionality? Thanks Solomon Garland, @vickiorr.bsky.social @jpjhall.bsky.social @ellieevolves.bsky.social for this review #MicroSky portlandpress.com/essaysbioche...
portlandpress.com
Invasive plasmids as ecosystem engineers—from mechanism to application
Abstract. Horizontal gene transfer, mediated by mobile genetic elements such as conjugative plasmids, is recognised as a major driver of bacterial innovation. While predominantly explored in the conte...
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Freya Harrison @friendlymicrobe.bsky.social · 11/08/2026
One of the best summaries I’ve seen of the whole sorry Arday situation. From Reddit.
A post from user PeterRum. It reads as follows. “ How about this. I've been fascinated by the story, as an Oxford and LJMU graduate who is a disabled person.

It has made me doubt myself, despite the fact I usually downplay my academic record. I want to be judged for my work. Still, I feel inherited  shame over this whole affair.

First hand I have seen academics being racist to felloow students in a casual way (not at Oxford tho). How much worse to be held back and told you were pushed forward.

Yes, it seems in this case they tried to rectify things by allocating a poster boy to show things had changed. But they made it worse for all of us by casting doubt on our achievements by allowing him to fake his.

I've got enough imposter syndrome without this shit.

Also, that poor, sad, delusional clown who spouted nonsense everyone pretended to believe. How much of it did he believe? Was he clinically delusional?”
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Freya Harrison @friendlymicrobe.bsky.social · 10/08/2026
I tagged the wrong Hall… this is by @hallfungalresearch.bsky.social & @katherine-baxter.bsky.social #MicroSky
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Mark O. Martin @markowenmartin.bsky.social · 10/08/2026
You have to be careful sourcing quotations. JBS Haldane's "An inordinate fondness for beetles" is much more nuanced; it is based on abundance. This is from his book, "What is Life?" And since I love stars and microbes, I would like to modify Haldane's quote.
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Freya Harrison @friendlymicrobe.bsky.social · 10/08/2026
How much do we currently know about the influence of bacterial-fungal interactions: on community function in environmental, health & industrial contexts? Thanks @halllab.bsky.social & @katherine-baxter.bsky.social for this review for Essays in Biochem! #MicroSky portlandpress.com/essaysbioche...
Example bacterial-fungal interactions in three different niches. Plant niches: synergistic interactions to promote plant growth by enhancing nutrient uptake, and antagonistic interactions where a bacterium prevents fungal infection. Human niches. Examples of C. albicans interactions across four different body niches showing synergy with bacteria in oral plaque formation, the CF lung and gut microbiome dysbiosis, and antagonism where bacteria prevent fungal infection in the vaginal microbiome. The built environment: co-occurrence of fungal species increases the resistance of Legionella to UV disinfection.
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Freya Harrison @friendlymicrobe.bsky.social · 10/08/2026
What do microbes actually use antimicrobial peptides for? How do they impact microbial communities? Thanks @lindaoyama.bsky.social for contributing this review to a special issue of Essays in Biochemistry on the social lives of bacteria #MicroSky portlandpress.com/essaysbioche...
portlandpress.com
From sequence space to ecological function: microbiome-derived antimicrobial peptides as community effectors and therapeutic leads
Abstract. Antimicrobial peptide research has long centred on host defence molecules, yet microbiomes themselves encode a diverse and increasingly important repertoire of peptide-based antimicrobials. ...
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Freya Harrison @friendlymicrobe.bsky.social · 10/08/2026
How the social lives of bacteria affect their pangenome: thank you @whelanfj.bsky.social for reviewing how community ecology affects pangenomes, and for a special issue of Essays in Biochemistry on the social lives of bacteria #MicroSky portlandpress.com/essaysbioche...
portlandpress.com
How the social lives of bacteria affect their pangenome
Abstract. Although the study of microbes started with type strains and reference genomes, advances in sequencing technology and new interest in mixed microbial communities have made us aware that a si...
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