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Casanova-Acebes Lab

@casanova-acebes.bsky.social
718 followers 792 following 55 posts

Curious & passionate group leader at @cniostopcancer.bsky.social Myeloid cells, Cancer & Immunotherapy. casanovaacebeslab.com

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La Dama Hueca del ático 7.291 @nazisrael.bsky.social · 03/10/2026
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Lung Cancer Research Foundation @lcrf.org · 05/08/2026
Every Wednesday, we are spotlighting women who are making a difference in the #LungCancer community – in labs, at hospitals, and by sharing their stories. Caroline is one of them. She shares a powerful message: "Women like me can get lung cancer." LCRF.org/women #WomenWednesday #ResearchMatters
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José Mª Fernández ༥༠ @jmfernand3z.bsky.social · 30/07/2026
Por desgracia, cada vez se duerme menos, y es menos común que las personas tengan unos horarios estables y compatibles con su organismo. ¡¡Ánimo con este proyecto, @casanova-acebes.bsky.social !! www.infosalus.com/salud-invest...
infosalus.com
El jet lag no sólo altera el sueño: científicos del CNIO investigan su posible papel en el desarrollo del cáncer
   El jet lag crónico y los horarios irregulares no sólo afectan al sueño o al rendimiento...
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Waggoner Lab @labwaggoner.bsky.social · 19/03/2026
@biorxivpreprint.bsky.social Diverse lung challenges elicit a conserved monocyte-to-macrophage differentiation blueprint @bainlab.bsky.social @crick.ac.uk @edinburghuni.bsky.social @chrysante-ili.bsky.social www.biorxiv.org/content/10.6...
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Pampa García Molina @pampa.bsky.social · 14/06/2026
La última semana de colegio en Madrid va a ser una salvajada
Teo se muere de calor en junio en el cole 36 grados en Madrid 19 de junio
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Journal of Experimental Medicine @jem.org · 06/06/2026
#Myeloid diversity in tumors: shaped by genes, location, and time. Review by Maria Nogales-Pons, Mariola Munárriz-Paños, Teresa Aceña-Gonzalo, & María Casanova-Acebes @casanova-acebes.bsky.social: rupress.org/jem/article/... 📘 Part of JEM #Cancer Collection: rupress.org/jem/collecti... #EACR2026
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Life Science Zurich @lifesciencezurich.bsky.social · 05/04/2026
Hey young scientists! Got what it takes to break down your research in just 3 min? Step into the spotlight & show off your scicomm superpowers! Win over the jury, inspire the crowd — & you might be the one representing Switzerland at FameLab international! 🌍✨ Apply now: www.famelab.ch
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Journal of Experimental Medicine @jem.org · 19/03/2026
#Myeloid diversity in tumors: shaped by genes, location, and time. New review from Maria Nogales-Pons, Mariola Munárriz-Paños, Teresa Aceña-Gonzalo, & María Casanova-Acebes @casanova-acebes.bsky.social @cniostopcancer.bsky.social: rupress.org/jem/article/... #CancerFocus #InnateImmunity
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Cell Press @cellpress.bsky.social · 20/03/2026
Special Issue from @cp-trendsimmuno.bsky.social: Perinatal and early life immunity. Explore the full issue: www.cell.com/issue/S1471-...

Image credit: Roberta Baldi (robertabaldi.com)
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 12/03/2026
Our view of new (and old but re-formulated) determinants of myeloid biology in tumors is out in @jem.org! Amazing work from #marianogales #mariolamunarriz, #teresaaceña, & a fantastic editing process (thanks @gaiajexpmed.bsky.social). Hope you like it! #cancerimmunitylab @cniostopcancer.bsky.social
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Academia Joven de España @academiajoven.bsky.social · 20/02/2026
📢Convocatoria 2026 de 10 plazas para la @academiajoven.bsky.social ➡️Plazo de inscripción abierto hasta el 28 de febrero (improrrogable) Más información en: academiajoven.es 👉convocatoria2026@academiajoven.es
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Enrique Cimientos @kikegasteiz.bsky.social · 02/02/2026
Steffi Graf ganó los 4 Grand Slams EL MISMO AÑO cuando tenía 19 años. Pero no era tenista, era mujer.
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Gaia Trincucci @gaiajexpmed.bsky.social · 15/01/2026
Welcome to @jem.org!
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 02/01/2026
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function | Science Immunology www.science.org/doi/10.1126/...
science.org
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function
Carboplatin reshapes macrophages to protect the heart through type I IFN signaling in mouse models.
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 02/01/2026
Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia | Science Immunology www.science.org/doi/10.1126/...
science.org
Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia
SFB colonization phenotypically alters alveolar macrophages, maintaining their antibacterial functions in inflamed interferon-rich lungs.
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Ivan Zanoni @lozanzi.bsky.social · 27/12/2025
#WeekendRead! #NeutrophilPower! @drusqui.bsky.social Aroca &co show @jem.org that neutrophil intrinsic circadian clock can be exploited by targeting CXCR4 to decrease vascular & myocardial damage by relocating neutrophils within the wound core, thus sparing injury to healthy neighboring cells!
doi.org
A circadian checkpoint relocates neutrophils to minimize injury
Aroca-Crevillén et al. identify a circadian checkpoint in neutrophils, mediated by the CXCL12–CXCR4 axis, that limits tissue injury by inhibiting their int
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Journal of Experimental Medicine @jem.org · 25/12/2025
New work by @ursmoerbe.bsky.social et al. provides an important framework for understanding gut-associated lymphoid tissues (GALT) diversity and function. rupress.org/jem/article/... 🎥 See a short video summary by Mörbe: youtu.be/iIWKSSnwFTg
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Lucie Van Emmenis @lucie-jexpmed.bsky.social · 24/12/2025
As 2025 is drawing to a close, @jem.org would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 tinyurl.com/2wrxk4mk
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Molly Przeworski @mollyprz.bsky.social · 22/12/2025
Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social, @natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n
biorxiv.org
What sets the mutation rate of a cell type in an animal species?
Germline mutation rates per generation are strikingly similar across animals, despite vast differences in life histories. Analogously, in at least one somatic cell type, mutation rates at the end of l...
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Gaia Trincucci @gaiajexpmed.bsky.social · 21/12/2025
#JEMLegacy @jem.org goes back to 1930 with the first description by William Tillett and Thomas Francis Jr. of C-reactive protein (CRP) in the sera of patients during the acute phase of pneumococcal pneumonia. @RockUPress @RockefellerUniv rupress.org/jem/article/...
rupress.org
SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS
1. Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pne
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Gaia Trincucci @gaiajexpmed.bsky.social · 21/12/2025
Today’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress. www.nature.com/articles/s41...
nature.com
Neutrophils preserve energy storage in sympathetically activated adipocytes - Nature
Neutrophil-derived IL-1β has a role in preserving lipid stores during metabolic stress.
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Science News @scinews.bsky.social · 14/12/2025
In 6 of 14 patients receiving immune checkpoint inhibitors, cell-free DNA methylation profiling revealed multiorgan damage with immune-related adverse events, often before symptoms appeared. @nejm.org www.nejm.org/doi/full/10....
nejm.org
Molecular Evidence of Multiorgan Damage in Patients with Immune-Related Adverse Events | NEJM
In 6 of 14 patients receiving immune checkpoint inhibitors, cell-free DNA methylation profiling revealed multiorgan damage with immune-related adverse events, often before symptoms appeared.
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Denis Wirtz @deniswirtz.bsky.social · 13/12/2025
Download our large database of postdoc fellowships in all fields of research. Database freely available to all; 281 fellowships. Download here: research.jhu.edu/rdt/funding-...
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 11/12/2025
“The collective” 
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Waggoner Lab @labwaggoner.bsky.social · 09/12/2025
Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes @cp-iscience.bsky.social www.cell.com/iscience/ful...
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Mass Lab @masslab.bsky.social · 06/12/2025
🧬🍽️ Your macrophages may be carrying your mother’s metabolic history! In our @cp-trendsimmuno.bsky.social article, we discuss how maternal diet programs lifelong immune function. authors.elsevier.com/sd/article/S... #ImmuneMemory #Macrophages #MaternalNutrition #DOHaD #EarlyLifeProgramming
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 06/12/2025
Could not like this topic better guys! Looking forward to read it! Disclaimer: i ate so much pistacchio ice-cream during my pregnancies 🥹🥲, poor baby TRMs!
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Kerry Hilligan @kerryhilligan.bsky.social · 06/12/2025
Calling all lung immunology enthusiasts 🫁 I’m excited to share this project where we designed and optimised a spectral cytometry platform to study immune responses in the mouse lung at steady-state and during viral infection. We hope this will be a useful resource for the field! Link below 👇
currentprotocols.onlinelibrary.wiley.com
Spatially Resolved Immune Profiling of the Murine Lung Using In Vivo Labeling and Spectral Cytometry
The lung is a structurally and immunologically complex organ, constantly exposed to airborne microbes, allergens, and pollutants. Understanding how diverse pulmonary immune cells respond to these cha....
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Saganism @sagan.bsky.social · 06/12/2025
"If we ruin the earth, there is no place else to go” ― Carl Sagan
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Mucosal Immunology @mucosalimmunol.bsky.social · 05/12/2025
Feel better during the day than at night during #influenza? Find out the “Role of IL-10 signaling in the #circadian control of host response to influenza infection” www.mucosalimmunology.org/article/S193...
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 05/12/2025
Do not miss this seminar, Roger is great!
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Andres Hidalgo @drusqui.bsky.social · 03/12/2025
Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.
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Eric Topol @erictopol.bsky.social · 02/12/2025
The NIH grant cuts in 2025 www.nytimes.com/interactive/...
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Oded Rechavi @odedrechavi.bsky.social · 02/12/2025
ERC applicants who made the shortlist and got invited to Brussels for an interview
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Caetano Reis e Sousa @reisesousalab.bsky.social · 01/12/2025
Key points on the need for continued animal use in scientific research. www.theguardian.com/science/2025...
theguardian.com
Why we have to continue with animal testing for medical research | Letters
Letters: Dr Robin Lovell-Badge and Prof Emma Robinson respond to an editorial on using new technologies to reduce the reliance on animal experiments
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Mucosal Immunology @mucosalimmunol.bsky.social · 26/11/2025
Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair in this work from @lizihegarty.bsky.social, @bainlab.bsky.social, and colleagues: www.mucosalimmunology.org/article/S193...
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Casanova-Acebes Lab @casanova-acebes.bsky.social · 26/11/2025
#PorLaCiencia que hacemos en @cniostopcancer.bsky.social
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Prof Sheena Cruickshank @sheencr.bsky.social · 14/11/2025
Climate change poses multiple challenges to our health. Our new article coauthored with @kathelse.bsky.social considers the rise in infections and pollution combines with the impact of climate change on our immune system and what we need to do to better understand this 🧪 🧵#EcoImmunology
nature.com
The role of ecoimmunology in tackling the emerging threats of climate change and the exposome
Nature Immunology - Climate change creates a multitude of challenges over the human life-course, influencing our exposomes and shaping immune function — requiring researchers to consider...
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Waggoner Lab @labwaggoner.bsky.social · 14/11/2025
Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity www.science.org/doi/10.1126/... @science.org
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Denis Wirtz @deniswirtz.bsky.social · 08/11/2025
We have written two reviews providing a practical guide and fundamentals of cell migration: (1) How to select an optimal cell migration assay, (2) How to analyze cell migration data. We also added a perspective on AI methods of analysis. Coming out soon in Nature Methods.
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Elizabeth McKenna @elizsmckenna.bsky.social · 30/10/2025
Now online in Cancer Discovery @aacrjournals.bsky.social: A Prognostic Signature for Lung Adenocarcinoma in Patients Who Have Never Smoked - by Wei Zhao, Maria Teresa Landi, and colleagues doi.org/10.1158/2159...
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Ricardo Henriques @henriqueslab.bsky.social · 28/10/2025
Using #LLMs for science👨‍💻💬? We have a fun tool for you: introducing #folder2md4llms. It converts an entire folder of docs/code/pdfs/pptx into a single markdown file that you can upload to your chatbot of choice. We use it to talk with our publications database or code repos github.com/HenriquesLab...
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Nature Reviews Immunology @natrevimmunol.nature.com · 28/10/2025
NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM #structuralimmunity #immunosky
nature.com
Structural immunity: immune cells as architects of tissue barriers - Nature Reviews Immunology
This Perspective presents a framework of ‘structural immunity’ that positions immune cells as architects of tissue structure. Beyond their roles in antimicrobial defence, we posit that immune cells co...
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Indivisible ❌👑 @indivisible.org · 19/10/2025
This is what democracy looks like. #NoKings
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Kal Tsanov @ktsanov.bsky.social · 15/10/2025
Many thanks to #AmyGladstein & #DavidFeldser for this great perspective on our recent paper @natcancer.nature.com. As they say in it (and have elegantly shown in their work): "‘Flip the switch’ and let nature show you the way!" 🔦🧬🐭 www.nature.com/articles/s43...
nature.com
Primary tumor chromatin landscape governs metastatic organotropism - Nature Cancer
Little is known about how mutations in genes encoding tumor suppressors influence metastatic site selection and whether sustained inactivation of such genes influences tumor maintenance at these sites...
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c0nc0rdance @c0nc0rdance.bsky.social · 15/10/2025
University administration: "We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible." Also university administration:
Stolen from the Internet, a sign that says "If Elevator does not move do a small jump it should move after", and a dirty-white freight elevator wall and aged elevator controls with only floors 1 and 2."

I have no idea where this really is, I just stole it off Wikimedia.
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DrArchivalGenomics @ehekkala.bsky.social · 12/10/2025
🧪🧬🔬🔭🥼🌎
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Thiago Carvalho @cyrilpedia.bsky.social · 10/10/2025
'All three awards (...) honored achievements rooted in fundamental research from decades ago. Some experts interpret the selections by the Royal Swedish Academy of Sciences as representing the importance of slow, basic science, work pursued out of a desire to better understand the world.'
nytimes.com
Nobel Prizes This Year Offer Three Cheers for Slow Science
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Naomi Moris @nmoris.bsky.social · 09/10/2025
The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍
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Rockefeller University Press @rupress.org · 03/10/2025
#Macrophages are presumed to attack antibody-opsonized #cancer cells by #phagocytosis. In @jcb.org, @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al find that macrophages attack adherent cells using #trogocytosis, or cell nibbling, instead of phagocytosis. rupress.org/jcb/article/...
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