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Chrysante Iliakis

@chrysante-ili.bsky.social
178 followers 391 following 3 posts

Former PhD student, now postdoc in the lab of Andreas Wack @crick.ac.uk Studying alveolar macrophage phenotype and function after lung infection 🔬🇬🇷🇩🇪

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Chrysante Iliakis @chrysante-ili.bsky.social · 26/07/2026
Gone but not forgotten: lung infection history shapes future respiratory immunity🫁 Check out our latest review @alicia-dirlam.bsky.social - we discuss how infection history alters lung immunity in the long term, and the translational implications for experimental models and therapeutic intervention!
mucosalimmunology.org
Gone but not forgotten: lung infection history shapes future respiratory immunity
After respiratory infection, the lung does not simply return to the prior baseline but adopts a new distinct post-infection steady state involving durable imprints that can shape tissue responses to s...
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Reposted by Chrysante Iliakis
Journal of Experimental Medicine @jem.org · 12/05/2026
TACI regulates marginal zone B cell development. New study from Daisy H. Luff, Lesley Vanes, Stefan Boeing, and Victor L.J. Tybulewicz @crick.ac.uk: rupress.org/jem/article/... #LymphocyteBiology #Bcells
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Reposted by Chrysante Iliakis
Calum Bain @bainlab.bsky.social · 12/04/2026
Our latest preprint in an awesome collaboration with the Wack Lab @crick.ac.uk. Led by @chrysante-ili.bsky.social, @woutertj.bsky.social and @isobelmouat.bsky.social. We show that monocytes follow a largely conserved differentiation blueprint in the 🫁 when elicited by distinct challenges.
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Reposted by Chrysante Iliakis
Asma Farhat @asmafarhat.bsky.social · 28/03/2025
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis. 🔗 www.science.org/doi/10.1126/...
science.org
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
Hematopoietic aging drives lung fibrosis and profibrotic macrophage influx, stalling their maturation via reduced Treg-derived IL-10.
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Reposted by Chrysante Iliakis
Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 19/03/2025
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
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Reposted by Chrysante Iliakis
Waggoner Lab @labwaggoner.bsky.social · 19/01/2025
Review Tissue-resident immune cells: from defining characteristics to roles in diseases www.nature.com/articles/s41...
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Reposted by Chrysante Iliakis
Ivan Zanoni @lozanzi.bsky.social · 11/01/2025
#WeekendRead! Ahn, Arthur &co show @CellHost&Microbe that pathogenic E. coli produce a metallophore that sequesters zinc in macrophages, stabilizing HIF1a & driving fibrosis in #IBD mouse models and Crohn Disease patients! www.sciencedirect.com/science/arti...
sciencedirect.com
Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
Inflammatory bowel disease (IBD)-associated fibrosis causes significant morbidity. Mechanisms are poorly understood but implicate the microbiota, espe…
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Reposted by Chrysante Iliakis
Marta Lebrusant @martalebrusant.bsky.social · 24/11/2024
How do NKT cells control epithelial cell biology and function in the small intestine ? Thrilled to share my PhD work investigating the cytokine driven crosstalk between NKT cells and epithelial cells in the gut @barrallab.bsky.social
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