iiinova — where your digital self keeps evolving

Helen Zenner @helenzsci.bsky.social · 10/09/2026

FOCUS-3D sounds fantastic. I can't quite believe the incredible amount of training data (& I like the fact that they included such a range of data.) I also like that it is possible to have a quick try with the method using the website option. I'm looking forward to the future developments as well!

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Helen Zenner @helenzsci.bsky.social · 21/08/2026

There's some really cool research in this list! This preprint from Suzi Kim, En Cai and team looking at T cell membrane organisation really stood out to me. Check out NanoMAP! www.biorxiv.org/content/10.6...

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Helen Zenner @helenzsci.bsky.social · 07/08/2026

I interviewed Anjali @thekusumbelab.bsky.social for @jcellsci.bsky.social in 2023, & we discussed the challenges of imaging bone. It’s fantastic to see their progress since then in their latest preprint! #sampleprep www.biorxiv.org/content/10.6... Interview: journals.biologists.com/jcs/article/...

Images extracted from Ding et al.
e, Images of diaphysis of mouse tibia obtained from a light-sheet microscopy with high-magnification insets immunostained for CD31 (green) and Endomucin (red). Scale bars: upper, 300 µm; lower, 100 µm.

f, 3D images of a murine tibia labeled with CD31 (green), α-SMA (red), and DAPI (grey). Insets displaying the blood vessels in the metaphysis. Scale bars: left, 800 µm; middle, 500 µm; right, 200 µm.

g, Mouse molar prior to and post-tissue clearing. 3D image of a murine molar tooth showing staining for Endomucin (green) and α-SMA (red). Inset showing the selected region of interest. Scale bars: left, 600 µm; right, 90 µm.

h, 3D images of a mouse tibia acquired on a light-sheet microscopy platform post-clearing with vascular surface reconstruction (yellow) and spot rendering of CD8α-positive T cells (violet). Scale bars: panoptic tibia, 1000 µm; inset, 300 µm.

i, Representative light-sheet images of a murine femur labeled with CD8α (violet), Perilipin (yellow), and DAPI (grey) generated by 3D reconstruction. Scale bars: panoptic femur, 500 µm; inset, 100 µm.

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FocalPlane @focalplane.bsky.social · 27/07/2026

ICYMI: Our preprint list covering the latest research in bioimage analysis is now up on FocalPlane. Let us know if you have any recommendations! focalplane.biologists.com/2026/07/24/m...

focalplane.biologists.com

Microscopy preprints: bioimage analysis - FocalPlane

Microscopy preprints: bioimage analysis - News

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Helen Zenner @helenzsci.bsky.social · 07/07/2026

🌞🏃Early call for preprints as I've got the day off on Friday! Let us know what preprints we should be adding to the @focalplane.bsky.social preprint list. This week we're focussing on exciting research that uses microscopy to answer questions in biology. focalplane.biologists.com/tag/preprints/

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Helen Zenner @helenzsci.bsky.social · 01/07/2026

I was so excited when @manuelthery.bsky.social agreed to write about this project for FocalPlane, but I didn't actually appreciate the scale it! The videos from the museum are incredible but the whole project is so much more. Check it out ⤵️

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Helen Zenner @helenzsci.bsky.social · 26/06/2026

I know for a fact that this list is 100% human-generated! For that reason, there are almost certainly some excellent research that I've missed.... Drop me a message if you have any suggestions that I should add to the list.

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Helen Zenner @helenzsci.bsky.social · 25/06/2026

The 1% from QED has made for an interesting debate here! My initial thoughts - Highlighting research esp preprints is a good thing - Lists are good, rankings maybe not so much - What does a ranking even mean? - Can the LLM read the figures? Isn’t looking at the data how we evaluate research!?

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Helen Zenner @helenzsci.bsky.social · 24/06/2026

Come for the beautiful images and stay for technical tips! Thanks to Benita Wolf for writing this fantastic highlight for FocalPlane on one of my favourite papers from 2026.

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Helen Zenner @helenzsci.bsky.social · 12/06/2026

It's #preprint list time on @focalplane.bsky.social. This week it's all about #bioimageanalysis. Drop me a message if you have any suggestions of preprints uploaded in the last 6 week.

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Helen Zenner @helenzsci.bsky.social · 12/06/2026

You can't beat a webinar that not only includes fantastic science but also sheep herding videos, Aardman characters and the tardis!

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Helen Zenner @helenzsci.bsky.social · 26/05/2026

I'm really excited for the 2nd webinar in our new series & I recommend checking out the abstracts from Laura & Sven on FocalPlane! I may also be looking forward to hearing whether it will be @ajcellbio.bsky.social or @joemckenna.bsky.social that will take on the tricky pronunciation of Brillouin!

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Helen Zenner @helenzsci.bsky.social · 17/02/2026

It was fantastic to chat with Aníbal about the @lisium-chile.bsky.social initiative and Aníbal’s journey to becoming a light-sheet specialist and project coordinator at Universidad Mayor, Chile.

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FocalPlane @focalplane.bsky.social · 24/01/2026

The next deadline for @jcellsci.bsky.social FocalPlane Training Grants is 20 February. These grants are open to early-career researchers in cell biology that require funding to attend a microscopy or bioimage analysis training course. www.biologists.com/grants/jcs-f...

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Guillaume Jacquemet @guijacquemet.bsky.social · 15/01/2026

🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social

abo.rekrytointi.com

Laboratory Engineer (Senior), in Advanced Imaging, 1.5.2026-31.12.2028

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FocalPlane @focalplane.bsky.social · 15/01/2026

The next stop on our ‘Imaging with…’ series is at Unidad de Microscopía Avanzada, Pontificia Universidad Católica de Chile. Meet the team (including the microscopes), discover how you can access the facility and learn their pet peeve! focalplane.biologists.com/2026/01/15/i...

focalplane.biologists.com

Imaging with… Unidad de Microscopía Avanzada, Pontificia Universidad Católica de Chile (UMA UC) - FocalPlane

Imaging with… Unidad de Microscopía Avanzada, Pontificia Universidad Católica de Chile (UMA UC) - News

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Helen Zenner @helenzsci.bsky.social · 09/01/2026

Fridays = preprints and #FluorescenceFriday. I'm looking forward to brightening up a cold, rainy day!

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FocalPlane @focalplane.bsky.social · 08/01/2026

🔬🔦Imaging spotlight: Lock-in-SIM Our latest imaging spotlight focusses on structured illumination microscopy, as Wenjie Liu & team present Lock-in-SIM. Check out their post to discover how & why you should try it with your SIM workflow: focalplane.biologists.com/2026/01/08/i...

focalplane.biologists.com

Imaging spotlight: Lock-in-SIM - FocalPlane

Imaging spotlight: Lock-in-SIM - Tools

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Helen Zenner @helenzsci.bsky.social · 07/01/2026

Wow, what a fantastic line up of instructors! Don't miss this opportunity to learn from some of the best in the business ❤️🔬

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Helen Zenner @helenzsci.bsky.social · 06/01/2026

The 2023 version of this meeting was fantastic and the 2026 programme promises to be just as brilliant! (I may also be thinking of chatting all thing microscopy in the Spanish sunshine while huddled inside in a cold and snowy Cambridge.) Sign up by Friday 16 Jan for the early-bird discount ⤵️

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Jennifer Waters @jencwaters.bsky.social · 06/01/2026

🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)! An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools. 🗓️ Apply online by Jan 30, 2026

meetings.cshl.edu

Quantitative Imaging: From Acquisition to Analysis

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

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Helen Zenner @helenzsci.bsky.social · 19/12/2025

Amazing research and such a fantastic scicomm video. I'd like to show it to my kids, but I'm afraid that it'll backfire and they'll use it to explain why all the clothes in their cupboards are unfolded despite the fact they were folded when they went in....

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Helen Zenner @helenzsci.bsky.social · 15/12/2025

Thanks for catching that background slide, Chris! And thanks for the shout to @the-node.bsky.social, @prelights.bsky.social & @focalplane.bsky.social, Jez. I'm sad to miss the UK membrane trafficking meeting this year, but hope to see you both at @jcellsci.bsky.social imaging meeting next year!

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Helen Zenner @helenzsci.bsky.social · 12/12/2025

Love this story from @andreamurillo.bsky.social. It was fun to think back to when @em-stp.bsky.social & @jemimaburden.bsky.social taught me EM and I got to play with gold*, sapphire^ and diamond**! I was so excited to get our paper published in JCS, & now I have the pleasure to be part of the team.

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Helen Zenner @helenzsci.bsky.social · 03/10/2025

Now that's image stitching! My fun discovery this Friday is this montage of 33 electron micrographs in published in @jcellsci.bsky.social in the 1960s. The original measured 3ft square!

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Heather Brown-Harding @microscopyed.bsky.social · 31/03/2025

Probably the coolest thing I learned at #ABRF was that there is a website called "core in a box" all about starting a core and management. Check it out! www.hopkinsmedicine.org/research/res...

hopkinsmedicine.org

Core in a Box

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BioImaging North America @bioimagingna.bsky.social · 31/03/2025

#MicroscopyMonday! Join @bioimagingna.bsky.social for a conversation with @clairebrown514.bsky.social as part of our Career Speaker series! Learn More & Register here buff.ly/9nB1qnC

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Helen Zenner @helenzsci.bsky.social · 27/03/2025

At the end of last year, I was lucky enough to chat with both Jennifer and Manu. Check out these interviews in @jcellsci.bsky.social to find out more about these extraordinary scientists!

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Helen Zenner @helenzsci.bsky.social · 18/03/2025

I always get a little nervous when attending conferences and knowing what to expect helps. We give a few insights into what to expect at #biologists100 & do reach out if you have any qs about the meeting. Also, there's a possibility that I once went to the wrong door at the ACC, so we explain all!!

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Helen Zenner @helenzsci.bsky.social · 13/03/2025

It's almost impossible to choose! We're excited to get the images back from the printers, along with something for another little project that our community sites are working on with our conference reporters 😉 for #biologists100.

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FocalPlane @focalplane.bsky.social · 06/03/2025

@the-node.bsky.social #biologists100 reporter @jens-cells.bsky.social is putting together a conference survival guide. What are your top tips for getting the most out of your conference experience.

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Helen Zenner @helenzsci.bsky.social · 21/02/2025

Good choice! But if we are allowed to play favourites, I thought this one from Malina Iwanski, Lukas Kapitein and team was pretty cool. www.biorxiv.org/content/10.1...

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Helen Zenner @helenzsci.bsky.social · 19/02/2025

As part of @biologists.bsky.social 100-year anniversary, it has been fun to look at the older journal content. For this post, I went all the way back to 1853 to look at early efforts at segmentation, wise words on peer review and the benefits of sharing tips and tricks rather than whole stories.

focalplane.biologists.com

Bringing the past into the future with JCS and FocalPlane - FocalPlane

Bringing the past into the future with JCS and FocalPlane - News

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FocalPlane @focalplane.bsky.social · 17/02/2025

There's still time to enter our image competition for your chance to win £250! All the shortlisted images will be displayed in our gallery at the Biologists @ 100 conference in Liverpool. Deadline: 24 February 2025 #Biologists100 focalplane.biologists.com/2025/02/05/t...

focalplane.biologists.com

Enter the Node-FocalPlane image competition - FocalPlane

Enter the Node-FocalPlane image competition - News

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FocalPlane @focalplane.bsky.social · 30/01/2025

#FocalPlaneCorrespondent Greg Redpath shares the first post in his biosensor series. Greg discusses the key considerations in selecting & using signalling biosensors and highlights GFP, the original biosensor. focalplane.biologists.com/2025/01/16/h...

focalplane.biologists.com

Highlighting signalling biosensors 1. - FocalPlane

Highlighting signalling biosensors 1. - How to

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FocalPlane @focalplane.bsky.social · 16/01/2025

We are looking for our next cohort of #FocalPlaneCorrespondents! If you are interested in getting some #scicomm experience alongside your research, check out our call and drop us an email if you have any questions. Deadline for applications: 20 January 2025

focalplane.biologists.com

Become a FocalPlane correspondent - FocalPlane

Become a FocalPlane correspondent - Discussions

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FocalPlane @focalplane.bsky.social · 10/01/2025

Our first preprint list for 2025 is focussed on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see on our list. focalplane.biologists.com/2025/01/10/m...

focalplane.biologists.com

Microscopy preprints - applications in biology - FocalPlane

Microscopy preprints - applications in biology - News

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FocalPlane @focalplane.bsky.social · 19/12/2024

As 2024 comes to a close we caught up with our fabulous #FocalPlaneCorrespondents Daniel Doucet, @sdutta.bsky.social and Greg Redpath. In our interviews we chat about their research, their FocalPlane posts and their experiences as correspondents. focalplane.biologists.com/2024/12/19/o...

focalplane.biologists.com

Our 2024 FocalPlane correspondents - Daniel Doucet, Subhajit Dutta and Greg Redpath - FocalPlane

Our 2024 FocalPlane correspondents - Daniel Doucet, Subhajit Dutta and Greg Redpath - Interviews

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Helen Zenner @helenzsci.bsky.social · 18/12/2024

I'm so full of ginger cookies from the office Christmas pot luck lunch that it is hard to think. Apologies if anyone receives any nonsensical emails from me this afternoon! #ThreeBiscuitRule

media.tenor.com

a purple curtain with the words did someone just say cookies written on it

ALT: a purple curtain with the words did someone just say cookies written on it

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Helen Zenner @helenzsci.bsky.social · 18/12/2024

And don't forget to tell all your friends that aren't on social media!

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FocalPlane @focalplane.bsky.social · 17/12/2024

#FocalPlaneCorrespondent Daniel Doucet interviews Kedar Narayan, the 2025 recipient of the Alan Agar @royalmicrosoc.bsky.social Award for Electron Microscopy. We learn about #volumeEM, big data challenges and the vEM community. focalplane.biologists.com/2024/12/14/v...

focalplane.biologists.com

VolumeEM: An Interview with Kedar Narayan - FocalPlane

VolumeEM: An Interview with Kedar Narayan - Interviews

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Helen Zenner @helenzsci.bsky.social · 16/12/2024

This is such a fantastic post, both for those getting started in imaging or if you need an update on the amazing developments in fluorescent probe research. Thanks Lina! Also, look out for our short interview with Lina, which will be up on @focalplane.bsky.social soon.

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Helen Zenner @helenzsci.bsky.social · 13/12/2024

This week's @focalplane.bsky.social preprint list will focus on new tools and techniques in microscopy, covering sample prep, probes, microscopy hardware and software. I'm just finalising the list now, so let me know if you have any recommendations from the last ~6 weeks!

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FocalPlane @focalplane.bsky.social · 12/12/2024

Following workshops at @harvardmed.bsky.social and #I2K2024, Ranit Karmakar shares an intro (plus access to course material) into how to use Segment Anything Model (SAM) to segment your microscopy images. Check it our here: focalplane.biologists.com/2024/12/10/s...

focalplane.biologists.com

SAM for Bioimage Analysis: A Comprehensive Guide - FocalPlane

SAM for Bioimage Analysis: A Comprehensive Guide - Education

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Joachim Goedhart @joachimgoedhart.bsky.social · 12/12/2024

Hey SkyWalkers, we've recently acquired a STED microscope and I was wondering what's your favorite structure to test/demo STED imaging (except for tubulin/actin)? Bonus points when: -can be done in HeLa cells -it's based on a genetically encoded part that is available from @addgene.bsky.social

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Seema Grewal @seemagrewal.bsky.social · 10/12/2024

Excited for #CellBio2024 (how is it only a few days away? 😱)! Looking forward to seeing old friends/colleagues and meeting new ones (…and hopefully seeing some ☀️). If you’d like to chat more about publishing in @jcellsci.bsky.social, drop me a message or find me at the @biologists.bsky.social stand!

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AIC at Janelia @aicjanelia.bsky.social · 10/12/2024

Check out this feature on @harikrushnan.bsky.social, one of our previous Advanced Microscopy Fellows (www.aicjanelia.org/fellowship) 👇

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