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Bending Lab UK

@bendinglab.bsky.social
2K followers 838 following 29 posts

T cell immunology group. Interested in T cell regulation and checkpoint receptor control of adaptive immunity. #CD4Tcells #TCRsignalling #immunotherapy

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Reposted by Bending Lab UK
The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 09/06/2026
Congrats to #ListerFellow David Bending and colleagues on @medresfdn.bsky.social funding to advance safer, more personalised cancer care 👏 David will investigate role of T peripheral helper cells in immunotherapy side effects. @bendinglab.bsky.social www.birmingham.ac.uk/news/2026/bi...
birmingham.ac.uk
Birmingham researchers receive funding to improve patients’ lives during and after cancer treatment - University of Birmingham
Three University of Birmingham researchers will investigate why cancer immunotherapy can cause harmful side effects and how to predict, prevent and treat them.
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Willem van Schaik @wvschaik.bsky.social · 13/03/2026
MRC curiosity-driven research reopens with new approach www.ukri.org/news/mrc-cur... MRC applicant-led funding opportunities reopen 7 Apr, experimental medicine opportunities opening 30 Apr Complete change in selection of project: no boards, shortlisted applicants -> in-person panel interview.
ukri.org
MRC curiosity-driven research reopens with new approach
The Medical Research Council (MRC) unpauses curiosity driven research funding and improves the funding process.
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Bending Lab UK @bendinglab.bsky.social · 06/02/2026
www.bbc.co.uk/news/article...
bbc.co.uk
UK’s £8bn research fund faces “hard decisions” as it pauses new grants
UKRI boss Ian Chapman said it had been told by the government to
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Bending Lab UK @bendinglab.bsky.social · 06/02/2026
How to reconcile the end statement “UKRI’s overall research and innovation budget is rising…” with earlier “we unfortunately expect to make a reduced number of awards to applications currently being assessed” This statement if anything makes things worse www.ukri.org/blog/mrc-fun...
ukri.org
MRC funding update
An update on MRC funding during UKRI’s transition, what’s changing, and the next steps for paused opportunities and reopening timelines.
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Alan McNally @alanmcn1.bsky.social · 23/01/2026
Has the MRC made a public statement yet
media.tenor.com
a man is sitting on a swing in the grass
ALT: a man is sitting on a swing in the grass
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BSI Midlands @bsi-midlands.bsky.social · 20/06/2025
It's today! Our #BSIMidlands25 kicks off with an overview of the history of clinical immunology in the Midlands by Dr Aarnoud Huissoon
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The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 19/06/2025
We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...
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James Thaventhiran @thav-lab.bsky.social · 19/06/2025
Honoured to receive this prize alongside an inspiring group of scientists. This will support our work to improve mRNA therapies for precision medicine. #mRNA #immunoSky #Science
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Bending Lab UK @bendinglab.bsky.social · 15/05/2025
Lovely work!
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Bending Lab UK @bendinglab.bsky.social · 12/05/2025
PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells •PD-1 & Lag3 exhibit layered control of CD4 T cell activation •Co-blockade enhances NFAT-dependent TCR transcription •NFAT inhibition reverses functional effects of anti-PD-1&Lag3 doi.org/10.1093/immadv/ltaf015 @imtadvances.bsky.social
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Damian Maseda @dmaseda.bsky.social · 12/05/2025
Congrats to the team! Very nice study. I find it especially interesting that blocking NFAT can compensate for the effects of anti-PD1/LAG3.
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Bending Lab UK @bendinglab.bsky.social · 12/05/2025
PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells •PD-1 & Lag3 exhibit layered control of CD4 T cell activation •Co-blockade enhances NFAT-dependent TCR transcription •NFAT inhibition reverses functional effects of anti-PD-1&Lag3 doi.org/10.1093/immadv/ltaf015 @imtadvances.bsky.social
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Eva Frickel @frickellab.bsky.social · 13/04/2025
🔥 Open postdoc position in human inflammation-driven control of infection! 🔥 Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5) Please share!
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The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 14/04/2025
Our new blog post spotlights the Lister Institute's ties with @unibirmingham.bsky.social, home to Lister Fellows past and present @bendinglab.bsky.social @agagambus.bsky.social @sarahdimeloe.bsky.social sky.social @therad-lab.bsky.social @tunglejic.bsky.social lister-institute.org.uk/shining-a-li...
lister-institute.org.uk
Shining a light on the Lister Institute’s connection to the University of Birmingham – Lister Institute
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Sarah Ross @sarahhross.bsky.social · 11/04/2025
#Immunology out now @science.org After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/49bKcTG By Jobin, Seetharama, Rüttger et al.
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Rebecca Drummond 🍄 @therad-lab.bsky.social · 11/04/2025
Check out latest work from @bendinglab.bsky.social - new insights into IFNg regulation of TCR signalling! 🧪 #immunosky
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Bending Lab UK @bendinglab.bsky.social · 11/04/2025
Now published @cp-iscience.bsky.social Work lead by David Lecky & Lozan Sheriff in collaboration with @therad-lab.bsky.social and @cameron-wraith.bsky.social showing how IFNg augments T Cell receptor signal strength to enhance type 1 Regulatory T (Tr1) cell development www.cell.com/iscience/ful...
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Waggoner Lab @labwaggoner.bsky.social · 08/04/2025
Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans @jem.org rupress.org/jem/article-...
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The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 08/04/2025
A new paper from #ListerFellow @linterman.bsky.social and colleagues explores the role of tertiary lymphoid structures (TLS) in #bcell immune response. @pnas.org doi.org/10.1073/pnas...
doi.org
Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS
The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...
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Lizzy Rosser @bcellsrosser.bsky.social · 28/03/2025
What better way to get into that Friday feeling than reading our new paper? First author @hlpeks.bsky.social and I will be doing a tutorial on @arrdept-ucldom.bsky.social next Tuesday lunchtime for those who are interested in reading the highlights 📖
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Journal of Experimental Medicine @jem.org · 28/03/2025
Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in humans with an XX chromosomal background. From @hlpeks.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin et al. rupress.org/jem/article/...
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Fränze Progatzky @franzeprogatzky.bsky.social · 23/01/2025
📣 New Review Alert! Do you think glial cells are simply neuronal support cells in the CNS? Did you know glial cells are integral to barrier organs? Check out our latest review exploring the fascinating crosstalk between glia and immune cells in the gut, lung and skin! #GlialCells #ImmuneSystem
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Daniel Utzschneider @danielutzschneider.bsky.social · 31/01/2025
Excited for our lab's FIRST paper #ScienceImmunology! 🎉 Led by @categraca.bsky.social & Amania Sheikh, with amazing collabs from Axel Kallies, Dane Newman, & @rickyjohnstone.bsky.social Huge thanks to reviewers & @claireolingy.bsky.social 🙌 #Tpex #onthescoreboard www.science.org/doi/full/10....
science.org
Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer.
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Otto Balsiger @obalsiger.bsky.social · 16/01/2025
The BSI has grants available for our members who want to help get more people excited about #immunology
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MRC AIM DTP @mrcaimdtp.bsky.social · 07/01/2025
⏰ Last few days before the deadline of midday (GMT) Friday 10 January if you are thinking of applying for one of our Medical Research Council fully funded 4 year PhD studentships at our partner institutions @uniofnottingham.bsky.social @unibirmingham.bsky.social or University of Leicester 🧵
more.bham.ac.uk
PhD Opportunities – MRC AIM
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Bending Lab UK @bendinglab.bsky.social · 13/12/2024
great opportunities!
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Doug Dyer @douglaspdyer.bsky.social · 13/12/2024
I’m so excited about this project, it’s going to reveal so much about how the glycocalyx works, amazing opportunity!!
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Altmetric @altmetric.com · 03/12/2024
BLUESKY MEGA-THREAD Altmetric is thrilled and also LITERALLY RELIEVED to officially announce: We are now tracking research attention as it happens on Bluesky! We have been picking up posts on the site since late Oct. Our team is on Bluesky all day answering questions. Let's get into it!
Blueksy Mentions are now in Altmetric.

It's been 84 years meme

#AcademicSky #HigherEd #MedSky #HMSky #Altmetrics #Medlibs #Metascience
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Altmetric @altmetric.com · 03/12/2024
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.
‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6
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Bluesky @bsky.app · 03/12/2024
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
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Maslowski MMIMiC Lab @mmimic.bsky.social · 03/12/2024
Before you go - a couple of fun side notes from the sup figures. FIRST, we could have missed this phenotype without the Timer system, EV1 shows comparison with the Nr4a1-GFP and Nr4a1-Timer. GFP gives the impression all is fine bc it sticks around-don't get the info of seeing it turned off. 10/12
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Bending Lab UK @bendinglab.bsky.social · 03/12/2024
Great fun to be involved in this project! 🧵below well worth a read 🧪
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Waggoner Lab @labwaggoner.bsky.social · 02/12/2024
T cell receptor–centric perspective improves single-cell analysis www.science.org/doi/10.1126/...
science.org
T cell receptor–centric perspective to multimodal single-cell data analysis
T cell receptor–centric perspective improves single-cell analysis.
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Willem van Schaik @wvschaik.bsky.social · 02/12/2024
The University of Birmingham is now on here! @unibirmingham.bsky.social
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Adrian Liston @labliston.bsky.social · 02/12/2024
Professorship of Infection / Immunity up for grabs in @cambridgeuni.bsky.social www.jobs.cam.ac.uk/job/49381/
jobs.cam.ac.uk
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
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Thiago Carvalho @cyrilpedia.bsky.social · 02/12/2024
"Nivolumab proved highly effective in advanced dMMR/MSI tumors. Expression of key innate immune receptors/ligands was the main predictor of a good treatment outcome, contrasting findings in melanoma and strengthening the rationale for tumor type–specific biomarkers for guiding #immunotherapy."
aacrjournals.org
The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment: Results from the Drug Rediscovery Protocol
AbstractPurpose:. The treatment efficacy of nivolumab was evaluated in patients with advanced, treatment-refractory solid mismatch repair deficiency/microsatellite-instable (dMMR/MSI) tumors, and in-d...
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Adrian Liston @labliston.bsky.social · 02/12/2024
What an opportunity!
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John Lindner @johnmlindner.bsky.social · 28/11/2024
I’m biased of course but this is a detailed new mechanism for the direct action of IL-2 on antigen-experiencing B cells, driving early/extrafollicular antibody responses! Congrats to @katyely.bsky.social and all co-authors on a job diligently and well done! Glad I could help #immunosky #bcells
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Aga Gambus @agagambus.bsky.social · 27/11/2024
Two fully funded PhD opportunities in our lab. Interdisciplinary, DNA replication, cancer research, structural biology… deadlines in early Jan. Open to international students. t.co/WEJJIU4zU4 www.findaphd.com/phds/project...
t.co
https://www.findaphd.com/phds/project/inhibitor-of-donson-gins-interaction-as-an-experimental-tool-and-potential-anticancer-strategy/?p178853
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Hepworth Lab @hepworth-lab.bsky.social · 28/11/2024
New PhD opportunity in the lab with @profjudiallen.bsky.social and @douglaspdyer.bsky.social looking at interactions between ILCs and the extracellular matrix. Application deadline Jan 10th 2025 - spread the word Bluesky immunologists! www.findaphd.com/phds/project...
findaphd.com
(Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester on FindAPhD.com
PhD Project - (Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester, listed on FindAPhD.com
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Sarah Dimeloe @sarahdimeloe.bsky.social · 28/11/2024
If you’re interested in a project please contact the lead supervisor to find out more, and make sure you complete the application form by 10th January!
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Sarah Dimeloe @sarahdimeloe.bsky.social · 28/11/2024
There’s a really exciting range of PhD projects on offer through the MRC “AIM” doctoral training partnership between the Universities of Birmingham, Leicester and Nottingham. 4-year funded studentships with great training opportunities too. Check out the options: more.bham.ac.uk/mrc-aim/phd-...
more.bham.ac.uk
PhD Opportunities – MRC AIM
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Aga Gambus @agagambus.bsky.social · 27/11/2024
One of this projects is ours 😀. Please send interested students our way!
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Bending Lab UK @bendinglab.bsky.social · 27/11/2024
Applications now open for our MRC AIM DTP 4 year fully funded PhD studentships across the Universities of Birmingham, Nottingham and Leicester. Deadline for applications is Friday 10th Jan 2025. More details and how to apply in the following link🧪 more.bham.ac.uk/mrc-aim/phd-...
more.bham.ac.uk
PhD Opportunities – MRC AIM
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Babraham Institute @babrahaminst.bsky.social · 26/11/2024
Delighted to welcome back Alyssa Silva-Cayetano for her 2024 Berridge Prize lecture on #ageing and the germinal centre response. Her research with the @linterman.bsky.social team brought together mice models, in silico modelling and human samples. Paper below! 👇
Alyssa and Martin Turner. Presentation slide showing the spatial organisation of the germinal centre reads: Spatial dysregulation of Tfh cells impairs vaccine responses in ageing
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British Society for Immunology @britsocimm.bsky.social · 26/11/2024
Our top-rated #bioinformatics #training course 'Omic data analysis and visualisation using R' starts in less than 2 weeks (9 Dec) Perfect for those who want to gain new #DataAnalysis and #omics skills 🤩 Don't miss out! Book your place now 👉 bit.ly/4gXvxOF
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Waggoner Lab @labwaggoner.bsky.social · 25/11/2024
REVIEW: Next-generation combination approaches for immune checkpoint therapy www.nature.com/articles/s41... @pamsharmamdphd.bsky.social
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Jon Lim, FRCP PhD @drjonlim.bsky.social · 24/11/2024
3️⃣ days left to apply! Application will close this Wednesday, 27 November 2024 👇 www.healthjobsuk.com/job/v6778827
healthjobsuk.com
Job vacancy: Clinical Fellow - Advanced Immunotherapy & Cell Therapy Team, The Christie NHS Foundation Trust, Manchester | trac.jobs
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Altmetric @altmetric.com · 23/11/2024
JUST DROPPED: “We practice Neurosurgery on SATURN in a country called “ILLUSIONLAND.” Attention details page for riveting article “Practise of Neurosurgery on Saturn” www.altmetric.com/details/1704...
altmetric.com
Report for: Practice of neurosurgery on Saturn
In the top 25% of all research outputs scored by Altmetric
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Thorn-Seshold Lab @thornsesholdlab.bsky.social · 22/11/2024
Wishing the Elsevier editors who desk-accepted this all the best for their next career moves. doi.org/10.1016/j.ij...
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