We developed a 50-plex imaging protocol using the MACSima platform to characterize the microarchitecture of germinal centers in secondary lymphoid tissues. This workflow combines tissue processing, a...

The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...

Natural intraepithelial T lymphocytes (T-IELs) are innate-like, intestine-resident T cells essential for gut homeostasis. These cells express self-reactive T cell antigen receptors (TCRs) due to thymi...

Description This 2025 collection of The Journal of Immunology features a special collection of articles curated by guest editor Patricia Gearhart. The collecti

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...

The nasal mucosa is the first immunologically active site that respiratory viruses encounter and establishing immunity at the initial point of path...

The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...

In this manuscript for the “Highlights of 2024” series, this is me trying to summarize recent discoveries regarding the emerging regulatory and effector roles of γδ T cells during sepsis, both in hum....

Calvanese et al. discovered that type I interferon is an essential upstream mediator for the development of tertiary lymphoid structures in the lungs. IFNAR1 signaling results in the production of LT....

Sep 08 – 11, 2025 │ Matrei am Brenner, Austria

The Babraham Institute in Cambridge, UK, invites applications for tenure-track and tenured group leader positions in the Immunology Programme. We w...

Professor Cindy Ma heads the Human Immune Disorders Laboratory at the Garvan Institute of Medical Research. She is a member of the Garvan Faculty, holds a