Nature Reviews Immunology - Adaptive immunity is indispensable to vertebrates, yet most living organisms defend themselves perfectly well without it. Here, I ask why somatically diversified antigen...

Tracy Tomlinson was offered the clinical trial for ovarian cancer at The Christie hospital in Manchester.

Mark England was diagnosed with bladder cancer in early December last year. He is the first patient to join the MANIFEST study, one of the largest immunotherapy studies in the country.

Mark England says numb fingers help him play guitar as researchers hope to change how disease is treated by investigating why immunotherapy does not benefit all

Cancer Research UK Manchester Institute says the extra cash will make a "huge difference" to its work.

Every year, thousands of cancer patients treated at The Christie NHS Foundation Trust, Manchester University NHS Foundation Trust and Northern Care Alliance NHS Foundation Trust choose to donate tissue samples to the Manchester Cancer Research Centre Biobank.

Here the authors show DNGR-1 expressed by cDC1s promotes CD8⁺ T cell priming to cytoskeletal neoantigens from dying tumor cells, thereby shaping cancer immune visibility and tumor evolution through im...

Cell therapy has revolutionised the landscape of cancer treatment, with therapies such as Chimeric Antigen Receptor T cells (CAR-T cells), showing remarkable efficacy in haematological malignancies, a...

New research has uncovered an unexpected way to stimulate the immune system against cancer: by subtly disrupting how tumour cells manufacture their proteins.

BJC’s Emerging Leaders collection recognises stand-out early-to-mid career researchers, clinicians, and educators within the field of oncology.

British Journal of Cancer - Tumour-infiltrating lymphocyte therapy in melanoma: ready for prime time?

TIL (Tumour-Infiltrating Lymphocyte) therapy is a transformative, cell-based immunotherapy approach now entering clinical practice for melanoma. This national summit brings together UK and internation...

The Christie Institute for Cancer Education has welcomed international colleagues from the National Cancer Institute of Ukraine (UNCI) as part of a new education partnership focused on bilateral shari...