Comprehensive spatial and immune profiling of metastatic mismatch repair–deficient colorectal cancer reveals response to immunotherapy

Neuraminidase A controls pneumococcal recognition and fate: deficiency enhances immune sensing and intracellular survival, while treatment promotes phagocytic clearance.

Call for Papers

Development and evaluation of two whole-blood flow cytometry protocols for monitoring patients treated with JAK inhibitors

Harnessing the duality of regulatory B cells: from identification of characteristic molecules to therapeutic targeting

Hyperactivation of the PI3K pathway in inborn errors of immunity: current understanding and therapeutic perspectives

Heterogeneity of regulatory B cells in autoimmune diseases: implications for immune equilibrium and therapeutic strategies

Growth factor supportive care for chemotherapy-induced neutropenia suppresses antitumour immunity in checkpoint blockade-responsive pancreatic cancer

Pharmacokinetics of hyaluronidase-facilitated subcutaneous immunoglobulin 10% in pediatric patients with primary immunodeficiency disease

High-affinity T cell receptor ImmTAC® bispecific efficiently redirects T cells to kill tumor cells expressing the cancer–testis antigen PRAME

High-affinity T cell receptor ImmTAC® bispecific efficiently redirects T cells to kill tumor cells expressing the cancer–testis antigen PRAME

Preclinical assessment of MAGE-A4-specific TCR-NK cells against solid tumors

M2 macrophages promote IL-10+B-cell production and alleviate asthma in mice

M2 macrophages promote IL-10+B-cell production and alleviate asthma in mice

Regulation of temporal cytokine production by co-stimulation receptors in TCR-T cells is lost in CAR-T cells

Pharmacokinetics, safety, and efficacy of 20% subcutaneous immunoglobulin (Ig20Gly) administered weekly or every 2 weeks in Japanese patients with primary immunodeficiency diseases: a phase 3, open-label study

Ex vivo comparative immunogenicity assessment (EVCIA) to determine relative immunogenicity in chronic plaque psoriasis in participants receiving Humira® or undergoing repeated switches between Humira® and AVT02

Neuraminidase A controls pneumococcal recognition and fate: deficiency enhances immune sensing and intracellular survival, while treatment promotes phagocytic clearance.

A rapid method to assess the in vivo multi-functionality of adoptively transferred engineered TCR T cells