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Reposted by Can Sarica

Lead-DBS @lead-dbs.org · 28/07/2026

Classic publication using Lead-DBS: In this article by Sarica et al., the authors tested MRI‑guided transcranial ultrasound stimulation (TUS) of M1, GPi, or occipital control in Parkinson’s patients with STN electrodes and... Check out the paper here 👇👇 doi.org/10.1126/scitranslmed.ady1883

Title card for publication: Transcranial ultrasound stimulation of motor networks in Parkinson’s disease informed by local field potential dynamics

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Reposted by Can Sarica

Research at UHN @uhnresearch.ca · 22/05/2026

Congratulations to Dr. Mojgan Hodaie, Senior Scientist at @kbi-uhn.bsky.social, who was awarded the University of Toronto Department of Surgery's prestigious 2026 Lister Prize. 🎉 This award recognizes excellence in surgical research and mentorship. 🔗 Read more: www.uhnresearch.ca/news/5-22-20...

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Reposted by Can Sarica

Research at UHN @uhnresearch.ca · 25/05/2026

#NewPublication 🚨 New research from @kbi-uhn.bsky.social shows transcranial ultrasound can safely and precisely stimulate the brain in #ParkinsonDisease, bringing us closer to non-invasive treatments and better care. 🔗 www.science.org/doi/10.1126/... @science.org @uhn.ca

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Reposted by Can Sarica

Lead-DBS @lead-dbs.org · 22/05/2026

New publication using Lead-DBS: In this article by Sarica et al., the authors tested MRI-guided transcranial ultrasound stimulation in Parkinson’s patients with STN electrodes and showed target- and brain-state–specific mod... Check out the paper here 👇👇 doi.org/10.1126/scitranslmed.ady1883

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Can Sarica @cansarica.bsky.social · 20/05/2026

🔊Today our study is out in @science.org Translational Medicine and on the cover: science.org/doi/10.1126/sc… 🙏 Huge thanks to all collaborators -particularly my shared first authors (Ghazel & Hamid) and mentors(Drs. Lozano and Chen), patients and friends who made this work possible. @uhn.ca

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Reposted by Can Sarica

mdcp-journal.bsky.social @mdcp-journal.bsky.social · 19/09/2025

Which is best, one side or two? A Systematic Review of Deep Brain Stimulation Approaches in PD and Essential Tremor. loom.ly/dT7cWGA

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Reposted by Can Sarica

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 29/09/2025

Deep Brain Ultrasound Augments Human Attention www.biorxiv.org/content/10.1101/202…

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Can Sarica @cansarica.bsky.social · 19/08/2025

Honored to be selected as one of the finalists for the DBS Think Tank Rising Stars Challenge. Grateful to the @dbsthinktank.bsky.social community for this opportunity and for fostering such an inspiring platform for advancing #DBS research. Excited to share my work on Aug 29! Links below 👇

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Reposted by Can Sarica

Michael Okun @michaelokun.bsky.social · 15/08/2025

Should you have DBS on one side or two sides of your brain? Do you know why the answer isn’t in the averages? A paper by Vetkas and colleagues presents pooled data and we should be cautious how we interpret. @parkinsondotorg.bsky.social

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Can Sarica @cansarica.bsky.social · 19/07/2025

www.nature.com/articles/s41... New study out! Is bilateral STN #DBS for #PD merely 2 × unilateral—or something more? We scanned 22 pts with #BOLD #fMRI: half with one lead on, half with both. Bilateral stimulation showed a synergistic suppression of sensorimotor cortex ‪@alfonsofasano.bsky.social

nature.com

Functional network differences between unilateral and bilateral deep brain stimulation of the subthalamic nucleus - npj Parkinson's Disease

npj Parkinson's Disease - Functional network differences between unilateral and bilateral deep brain stimulation of the subthalamic nucleus

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Can Sarica @cansarica.bsky.social · 24/06/2025

Thrilled to join the 24th International Symposium for Therapeutic Ultrasound #ISTU2025 in Banff! We shared our latest work on ultrasound in movement disorders with 4 oral presentations. Great to reconnect with colleagues worldwide—huge thanks to Samuel Pichardo & Laura Curiel, for organization.

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Can Sarica @cansarica.bsky.social · 10/05/2025

movementdisorders.onlinelibrary.wiley.com/doi/10.1002/... Happy to share our work in @movedisorder.bsky.social We compared outcomes of bilateral #HIFU and #DBS in essential tremor, identified thalamic hotspots using probabilistic mapping. @fusfoundation.bsky.social @alfonsofasano.bsky.social

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Reposted by Can Sarica

Matthias Nau @matthiasnau.bsky.social · 01/04/2025

Invasive Deep Brain Stimulation is often a last resort for people with Parkinson's disease & other conditions. Here, Darmani et al show direct electrophysiological evidence that *non-invasive* ultrasound stimulation is effective even in deep brain structures. Amazing! www.nature.com/articles/s41...

nature.com

Individualized non-invasive deep brain stimulation of the basal ganglia using transcranial ultrasound stimulation - Nature Communications

Transcranial ultrasound stimulation (TUS) is a non-invasive method to modulate deep brain activity. Using direct recordings from implanted electrodes, we showed that TUS engages the human globus palli...

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Reposted by Can Sarica

Michael Okun @michaelokun.bsky.social · 30/03/2025

Wouldn't it be cool to be able to stimulate deep w/in the brain w/o the need for brain surgery, and without actually making a physical lesion in the brain (i.e. FUS or pallidotomy)? This paper provides 'proof of concept' that a transcranial ultrasound stimulation (TUS) approach may be achievable.

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Can Sarica @cansarica.bsky.social · 22/03/2025

Proud to share the first of our two-part sequel papers on the #TUS-#DBS project! t.co/yrGRcdpjXn We recorded local field potentials using #PerceptPc #DBS systems in #Parkinsons patients while applying transcranial ultrasound stimulation (#TUS) — aiming to better understand its effects & mechanisms.

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Can Sarica @cansarica.bsky.social · 19/03/2025

Our paper on the safety of transcranial ultrasound stimulation in #Parkinson patients, published in @movedisorder.bsky.social, has been recognized as one of the #TopCitedArticles! Huge thanks to my incredible co-first authors Drs. Samuel and Ding. onlinelibrary.wiley.com/doi/full/10.... @wiley.com

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Can Sarica @cansarica.bsky.social · 26/02/2025

Brain Stimulation Conference 2025 wraps up today! Grateful for the opportunity to present my latest work as a poster and to receive valuable feedback from some of the leading experts in the field. Already looking forward to next one! #BrainStim2025 #BrainStimConf @braistimjournal.bsky.social

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Can Sarica @cansarica.bsky.social · 25/02/2025

We’re thrilled to hear from Dr. Andreas Horn, this year’s Brain Stimulation Early Career Award winner, at #BrainStimConf today! Congratulations on this well-deserved recognition @andreashorn.org #BrainStim2025 @braistimjournal.bsky.social @braincircuits.bsky.social

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Can Sarica @cansarica.bsky.social · 09/02/2025

Thank you! It was wonderful to be in Boston and to have the opportunity to connect with you and the team.

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Can Sarica @cansarica.bsky.social · 08/02/2025

Honored to be invited by @foxmdphd.bsky.social to give a talk on mapping tremor response zones in thalamus @harvardmed.beky.social this Friday. It was a privilege to discuss with brilliant scientists like Dr. Cosgrove, Dr. Horn @andreashorn.org, Dr. Bubrick, and Dr. Siddiqi @shansiddiqi.bsky.social.

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Can Sarica @cansarica.bsky.social · 05/01/2025

doi.org/10.3171/2024... Thrilled to unveil our multicenter study—featuring Bern, Hannover, Innsbruck, Milan, Oxford, & Toronto—mapping thalamic #DBS response regions for central post- #stroke #pain. A step forward in understanding and treating this challenging condition! @lead-dbs.org

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Can Sarica @cansarica.bsky.social · 11/12/2024

Check out our new book chapter on ethical challenges in the future of #DBS, authored by Cletus Cheyuo! It's featured in "Ethical Challenges for the Future of Neurosurgery," @springernature.bsky.social edited by Mark Bernstein and Ahmed Ammar. 📚 rdcu.be/d24nd

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Can Sarica @cansarica.bsky.social · 04/12/2024

t.co/SnttfVdhTF In our latest study, we explored metaplastic effects on TUS-induced plasticity. We found that priming theta burst #TUS (tbTUS) with #TMS extends plasticity duration, while delivering #TMS immediately after #tbTUS abolishes its induction. Check it out at @sfnjournals.bsky.social!

t.co

https://www.jneurosci.org/content/44/44/e2438232024

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Can Sarica @cansarica.bsky.social · 27/10/2024

My close friends know I’ve been systematically visiting #UNESCO #WorldHeritageSites (WHS) and have now reached #277! Instead of sharing all my travel photos here, I’ll be updating my banner with WHS photos I’ve personally taken—starting with 🇺🇸 #Cahokia Mounds State Historic

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Can Sarica @cansarica.bsky.social · 24/10/2024

Thrilled that the best time of the year is here: the #GairdnerScienceWeek Laureate Lectures! It was a privilege to hear from the 2024 @GairdnerAwards laureates Shankar Balasubramanian, David Klenerman, Pascal Mayer @PascalMAYER16, and Michel Sadelain. Their presentations were

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Can Sarica @cansarica.bsky.social · 28/09/2024

After a long break, my running mate Gozde and I got back into it with a 10k night run—double the fun compared to a day run, and triple the fun with the after-party DJ! #britanightrun

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Can Sarica @cansarica.bsky.social · 18/09/2024

The #WSSFN2024 Congress in Chicago was a huge success! Grateful to the organizers for making this incredible event happen @mhodaie. It was fantastic to see current and former Toronto fellows throughout the venue. Thrilled to present our latest research and excited for the

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Can Sarica @cansarica.bsky.social · 18/08/2024

Is the optimal target for #MRgFUS ablation different in #PD patients versus those with #ET? Discover the findings in our latest paper in @MDJ_Journal, led by my colleague @CCheyuo . @kalialabs @mhodaie @DrAlfonsoFasano @UofTNeuroSurge...

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Can Sarica @cansarica.bsky.social · 14/07/2024

We concluded @itrusst #FUN24 with a successful workshop, sponsored by @Brainbox_Neuro @Brainbox_Init , and attended by over 30 participants.

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Can Sarica @cansarica.bsky.social · 12/07/2024

We completed the first session of day two at @itrusst #FUN24 with three excellent presentations from Elena Vicari @EPFL_en, Taylor Webb @UUtah, and Neha Chauhan @Sunnybrook. @elevicari @tjjlemaire @OAkouissi @splacour40 @_smicera @HarrietLeaBanks @KullervoHynynen @MKFlugge

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Can Sarica @cansarica.bsky.social · 12/07/2024

We’re thrilled to welcome the #FocusedUltrasound Neuromodulation Society to @itrusst #FUN24 in Toronto! Ready for an exciting second day filled with great presentations.

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Can Sarica @cansarica.bsky.social · 11/07/2024

Our third speaker of #fun24 today, Hyunjoo Jenny Lee from @kaistpr, showcased novel technologies in the #focusedultrasound field, ranging from wireless and wearable systems to artifact-free closed-loop systems. @tobergmann

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Can Sarica @cansarica.bsky.social · 11/07/2024

Our second invited speaker, Ghazaleh Darmani, delivered an excellent lecture on how #LFPs change in response to #focusedultrasound stimulation in #ParkinsonsDisease patients in the second session that was moderated by Elsa Fouragnan @EFouragnan from @PlymUni.

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Can Sarica @cansarica.bsky.social · 10/07/2024

Exciting day in the lab! We've just received our new @Fraunhofer focused ultrasound device. Can't wait to dive into research with this cutting-edge technology! @JFNankoo @RobertC21093233

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Can Sarica @cansarica.bsky.social · 10/06/2024

We had an amazing four days at the #assfn2024 conference in Nashville, immersing ourselves in insightful presentations and sharing our own work. Already looking forward to the next @ASSFNeurosurg meeting in @CleClinicNS in 2026!

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Can Sarica @cansarica.bsky.social · 01/06/2024

📢 Important @itrusst #FUN24 Congress Updates! 🗣️ - Oral presentations announced. - Early bird registration & late-breaking abstract submission deadlines extended to June 9, 2024. - Welcome our distinguished speaker, Andres M. Lozano, presenting "Potential Therapeutic Uses of Foc

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Can Sarica @cansarica.bsky.social · 28/05/2024

Only 44 days until our @itrusst #FUN24 meeting! We can't wait to see all #FocusedUltrasound enthusiasts in Toronto. Don't miss out—this week is your last chance to register at discounted rates. For program details and registration, visit: www.fun24.ca

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Can Sarica @cansarica.bsky.social · 28/05/2024

Excited to share our latest #FocusedUltrasound study by @TalytaGrippe in @MDJ_Journal! We provide more safety and efficacy data on low-intensity #FUS for #Parkinson's Disease. Read more: movementdisorders.onlinelibrary.wil… @movedisorder...

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Can Sarica @cansarica.bsky.social · 05/04/2024

Announcing our third speaker, Emilie Franceschini from Aix-Marseille University @univAMU_Europe @LMA_UMR7031 #IUSTI, presenting "Ultrasonic neurostimulation of dorsal root ganglion neurons: exploring molecular and physical mechanisms" at @itrusst's #FocusedUltrasound

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Can Sarica @cansarica.bsky.social · 04/04/2024

🌟 Important Announcement! 🎉 The deadline for abstract submission has been extended to April 21, 2024. Seize this opportunity to present at the prestigious @itrusst #FocusedUltrasound #Neuromodulation Conference (#FUN24) in Toronto, Canada, from July 11th-13th, 2024. Don't miss

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Can Sarica @cansarica.bsky.social · 04/04/2024

Introducing our second invited speaker for @itrusst's #FocusedUltrasound #Neuromodulation Conference (#FUN24) in Toronto, Canada, from July 11th-13th, 2024; Hyunjoo Jenny Lee from the Korea Advanced Institute of Science and Technology (KAIST) @kaistpr. Join us as she shares

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Can Sarica @cansarica.bsky.social · 03/04/2024

📢 Exciting news for the #FocusedUltrasound Community! We're thrilled to announce our first invited speaker for the @itrusst Focused Ultrasound Neuromodulation Conference (FUN24) on July 11th-13th, 2024 in Toronto, Canada: Jan Kubanek from University of Utah @UUtah. 🧠 Jan

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Can Sarica @cansarica.bsky.social · 26/03/2024

This Sunday, I achieved a personal milestone by completing my longest distance yet—35.4k in the #AroundTheBay road race in Hamilton. Grateful for my amazing support team whose encouragement doubled my joy. Big hugs to them! 🏃‍♂️ 🎉

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Can Sarica @cansarica.bsky.social · 25/03/2024

🧠 Dive into our latest review paper on intracranial #hemorrhage in #Deepbrainstimulation surgeries in @TheJNS authored by the brilliant @CCheyuo! A must-read for anyone in the field! 📝#Neurosurgery #DBS @mhodaie @kalialabs @CA1CA2CA3CA4 doi.org/10.3171/2024.1.JNS232385

doi.org

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Can Sarica @cansarica.bsky.social · 07/03/2024

Gratitude to @PNASNews and @PNASNexus for recognizing the invaluable efforts of reviewers in 2023. It was truly an honor to serve as a reviewer for both journals, playing a part in advancing impactful scientific contributions....

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Can Sarica @cansarica.bsky.social · 12/02/2024

Excited to share our latest review article featured in the upcoming special issue on #neuromodulation, edited by @DrAlfonsoFasano and Vibhor Krishna for #Neurotherapeutics journal. @BenDavidson__ @RobertC21093233 @UofTNeuroSurge!...

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Can Sarica @cansarica.bsky.social · 30/12/2023

Gratitude, @NeuroKarger, for acknowledging the reviewers of the year! Proud to contribute to our flagship journal! Wishing you a Happy New Year🎄 @CCheyuo @StefanLang_MD @kalialabs @BenDavidson__ @oliverflouty @mhodaie @DrAlfonsoFasano...

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