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Andreas Müller

@andimicroscopy.bsky.social
717 followers 803 following 42 posts

Scientist at Paul Langerhans Institute Dresden and Visiting Scientist at HHMI Janelia Research Campus. Interested in the structural features of pancreatic islet cell function and signaling. 🔬

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Reposted by Andreas Müller
HHMI @hhmi-science.bsky.social · 11/10/2026
Every cell has an organelle signature — a “fingerprint” created from the shape, size, & arrangement of its internal structures. Scientists at our Janelia Research Campus can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹 Feliciano Lab@
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Haucke lab @volkerhaucke-lab.bsky.social · 10/10/2026
Research Associate and Postdoc Opportunities! I am happy to announce that I will establish a new laboratory at Hong Kong University of Science and Technology (HKUST) to start a major research program supported by a multi-year FTRSS grant.
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Mill_lab @cilialab.bsky.social · 09/10/2026
Nikon just announced it has withdrawn first place in this year’s #SWiM after finding winning video did not comply with its generative AI rules. www.nikonsmallworld.com/news/nikon-s... Letter still open until Monday- this is a starting point to engage & discuss how AI is transforming microscopy 🔬
nikonsmallworld.com
Nikon Small World in Motion Video Statement | News | Nikon Small World
An update from Nikon Small World regarding the 2026 Small World in Motion first-place winning video: After thoroughly re-evaluating the video and supporting materials and consulting with members of…
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Mill_lab @cilialab.bsky.social · 08/10/2026
We are at 302 signatories from 30 countries and territories... let's keep up this momentum. Nikon may be quiet but we are not.... stand up for imaging integrity! #NikonSWiM
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Andreas Müller @andimicroscopy.bsky.social · 08/10/2026
Grant deadline is approaching and of course the kids are getting sick.
static.klipy.com
Tired Baby on Play Area Floor
ALT: Tired Baby on Play Area Floor
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Florian Jug @florianjug.bsky.social · 08/10/2026
Just in case anyone here vibes with this: docs.google.com/forms/d/e/1F...
docs.google.com
Sign the open letter to Nikon Small World in Motion
The winning video in Nikon's 2026 Small World in Motion competition is captioned 'abnormal beating of airway cilia from a child with primary ciliary dyskinesia'. It has been seen worldwide, including ...
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Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 07/10/2026
In our new paper by Kata Szabó et al. we present optimised sample-preparation workflows for volume electron microscopy for entire small marine organisms. The workflow includes high-pressure freezing, various freeze substitution protocols and synchrotron […] [Original post on biologists.social]
X-ray image of a platynereis annelid worm larva collected at the European Sycnrotron Facility at Grenoble. The left image shows morphological rendering of a 6-day-old Platynereis scanned at 100 nm/px, the right images show individual image planes of the same larva scanned at 55 nm/px or 20 nm/px.
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Andreas Müller @andimicroscopy.bsky.social · 01/10/2026
Nur zweimal Friedrich!
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Reposted by Andreas Müller
Estibaliz Gómez de Mariscal, PhD @gomez-mariscal.bsky.social · 25/09/2026
🚨I have open PhD positions in my new lab at #NIMSB🚀!! Deadline Oct-16 nimsb.unl.pt/join-us/ 🌟I'm looking for motivated candidates who are eager to join a highly multidisciplinary team and study the intracellular dynamics of cancer cell migration using advanced computational methods and microscopy👾
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Valentin Dunsing-Eichenauer @dunsingvalentin.bsky.social · 25/09/2026
#FluorescenceFriday: Given the recently grown interest in ciliary beating, here is a movie of beating cilia in a human airway model that I captured last week with lattice light-sheet microscopy. No AI „processing“, this is the raw data! Frame rate is ca. 170fps, displayed here at 25fps.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 23/09/2026
Is anyone working for Nikon on here?? You really need to get them to understand the impact this is having on their brand. We loved the image contests--they are great PR for science and microscopy--but this is seriously damaging that reputation.
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 23/09/2026
What if any dataset, any size, any number of dimensions, opened in a browser tab from a link? 🔬🧪💻 Luxar is out today: write it in Python, share it as a link, explore it in any browser. Open source. 🧵 @biohub.org Preprint: doi.org/10.5281/zen... Code: github.com/royerlab/luxar
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MwahahahahahadScientist @mads100tist.bsky.social · 23/09/2026
"embrace slop to create things that do not exist from a sample that was probably donated by some kid with the premise of studying their disease" Conflating AI and genAI on purpose is loser behavior and Nikon Small World will always have that label to me 🧪
A screencap from the interview where the researcher says"

His advice to other researchers considering entering the competition is straightforward: “Take care of the sample, use as little light as possible when working with living cells, and embrace AI to reveal the hidden beauty in your data. Most importantly, keep recording. The best moment usually appears right after you decide to stop.”
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Andreas Müller @andimicroscopy.bsky.social · 23/09/2026
Ha, I knew it.
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paveltomancak.bsky.social @paveltomancak.bsky.social · 20/09/2026
21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk! marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
marie-sklodowska-curie-actions.ec.europa.eu
MSCA Postdoctoral Fellowships 2026 receives record number of applications
The 2026 call has attracted considerable interest from the research community with 21,627 applications submitted.
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Andreas Müller @andimicroscopy.bsky.social · 18/09/2026
It feels like we are still in Plato's cave.
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Andreas Müller @andimicroscopy.bsky.social · 18/09/2026
Well, it won the contest. 😉
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Andreas Müller @andimicroscopy.bsky.social · 18/09/2026
Yes, seems highly altered. Still, my guess is that also AI asignment of organelle fluorescent signals has been involved.
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Andreas Müller @andimicroscopy.bsky.social · 18/09/2026
Ah, so it might be AI coloring of label-free images or something similar.
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Christophe 🔬 Leterrier @christlet.bsky.social · 18/09/2026
Questions about the recently announced Small World in Motion winner @healthcare.nikon.com
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MwahahahahahadScientist @mads100tist.bsky.social · 17/09/2026
We are at a critical point in which we need to decide whether we like our job and whether we like our colleagues, and whether we like our community, and what we can do to make it stronger. Otherwise, isolationism will lead to communities going the way of the Dodo 🧪
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Diabetologia @diabetologiajnl.bsky.social · 01/09/2026
Our Sept cover shows a mouse pancreatic islet (alpha cells in pink & beta cells in blue), highlighting single cell calcium responses to stimuli. In this issue, Hart et al report that SST inhibits insulin secretion by restraining alpha cell calcium and cAMP link.springer.com/article/10.1...
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HHMI @hhmi-science.bsky.social · 03/09/2026
(1/2) When Janelia set out to map every neuron in the fly brain in 2008, many thought it couldn’t be done. Nearly 20 years later, a complete wiring diagram of the 166,000+ neurons of the adult male fruit fly is helping to reveal the brain’s secrets: bit.ly/4zT7jPf.
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Diabetologia @diabetologiajnl.bsky.social · 02/09/2026
Up front and free to read in our Sept issue #editorspicks: Islet ultrastructure: past achievements and future directions doi.org/10.1007/s001...
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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 27/08/2026
Very happy to see our Nature Reviews Molecular Cell Biology Roadmap out! A fantastic collective effort, led by Carsten Janke and Zdenek Lansky, together with an amazing group of colleagues, and sparked by inspiring discussions at the Fondation des Treilles. www.nature.com/articles/s41...
nature.com
Towards a systems-level view of the microtubule cytoskeleton and its functions in physiology and disease - Nature Reviews Molecular Cell Biology
Microtubules are essential components of the cytoskeleton, yet important links between their molecular properties and organismal functions remain unresolved. In this Roadmap, Janke et al. discuss key ...
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Deutsches Zentrum für Diabetesforschung (DZD) @diabresearch-dzd.bsky.social · 27/08/2026
🧬 An interesting review: Islet ultrastructure: past achievements and future directions highlights how advances in imaging are deepening our understanding of pancreatic islets and diabetes. @andimicroscopy.bsky.social #DiabetesResearch #Islets #Diabetologia
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Christophe 🔬 Leterrier @christlet.bsky.social · 20/08/2026
So I'm learning today that there's a researcher funded by the ERC who publishes philosophy about *checks bibliography* why men should not do an equal share of house cleaning, why blackface is OK, why monarchy *stops reading*
static.klipy.com
Man Smiles and Closes Laptop
ALT: Man Smiles and Closes Laptop
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Chad Topaz Queer DEI Race Traitor @chadtopaz.bsky.social · 31/07/2026
🧵🚨: Remember the recent #genAI cheating scandal at Brown? Everyone talks about the average score drop from take-home midterm to proctored final: 95.7 → 48.8. That number alone can't settle anything. But the released data can, and almost nobody has looked at it. So we did! Read on. #AcademicSky
arxiv.org
What exam scores can and cannot prove about unauthorized AI assistance: Evidence from a highly public classroom episode
In spring 2026, an economics professor at Brown University gave a take-home midterm and, after unusually high scores, made the final exam proctored. Among the 59 students who completed the course, ave...
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Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 30/07/2026
If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" link.springer.com/article/10.1038/s… […] [Original post on biologists.social]
Figure showing different Erdős–Rényi-type random graphs with different preferential attachment, resulting in increasingly modular graphs. Images of Syncytial nerve net of the ctenophore Mnemiopsis, Schematic of an incision experiment carried out by Romanes on the scyphosoan medusa Aurelia,  Schematic of the localised spread of activity in a hydrozoan nerve net, where different non-overlapping nerve nets mediate distinct behaviours. The hydromedusa Aglantha digitale with its giant motor system shows a centralised arrangement.
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Stanley Heinze @stanley-heinze.bsky.social · 30/07/2026
New preprint! www.biorxiv.org/content/10.6... Nearly a decade after starting the project, the first major results from our comparative connectomics work is online! Comparing the head direction circuits of the central complex in bees, ants and flies, recapitulating >300million years of evolution.
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Prof. Stefan Rahmstorf @rahmstorf.bsky.social · 24/07/2026
Holiday in the climate emergency. No that’s not AI or edited, just a snapshot I just took with my phone on Lacanau beach in France. What future will this boy grow up in? It is in our hands, but time is running out.
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Aafke Gros @aafkegros.bsky.social · 24/07/2026
Microscopy Nodes 3.1 is out for Blender 5.2! 🎉 This has cool new features for conditional masking, working with even larger data (regional upscaling), and data manipulation! Watch the new youtube tutorials that explain the features: www.youtube.com/playlist?lis...
A FIB-SEM plankton visualization where the top shows only the volumetric data of the chromosomes, and the bottom a normally sliced region of the cell. A fluorescence microscopy dataset where a region has been reloaded to be much higher resolution
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EuroCilia2027 @eurocilia.bsky.social · 24/07/2026
📣 Abstract submission and early registration are now OPEN for the 7th European Cilia Conference—an official EMBO workshop! 📅 8–12 March 2027 📍 Stresa, Italy Submit and register: meetings.embo.org/event/27-cilia www.eurocilia.eu #EMBOCilia #Cilia2027
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Diabetologia @diabetologiajnl.bsky.social · 20/07/2026
From early electron microscopy of insulin granules to 3D islet reconstructions, this review follows the evolution of islet ultrastructure imaging and looks ahead to link structure with function in diabetes. link.springer.com/article/10.1... 🔓 @plid-info.bsky.social @hhmijanelia.bsky.social
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John Bogovic @bogovicj.bsky.social · 17/07/2026
It's an exciting day for #Fiji users! Now read and write @zarr.dev v3 and #OMEZarr v0.5. Don't want a million tiny files in your #zarr? Shard that sucker! Read the details here forum.image.sc/t/fiji-can-r...
forum.image.sc
Fiji can read and write Zarr3 & OME-Zarr v0.5 (new N5 release!)
Updating your Fiji-Latest installation will give you the newest versions of the N5 library, enabling OME-Zarr v0.5 / Zarr v3 support with sharding! What's new? Reading zarr 3 datasets (sharded and u...
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FX Coudert @nanoporous.net · 17/07/2026
Ironically, as @mart1oeil.eu showed, there are telltale signs that the piece was edited with ChatGPT: many links include "?utm_source=chatgpt.com" If even Science editorial team cannot afford good human editing, that's worrying
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BWJones @bwjones.bsky.social · 26/06/2026
This is one of the most beautiful cross sections of cilia I've ever seen in our data, found by @csigulinsky.bsky.social. It is perfectly perpendicular to the plane of imaging which brings up an important point ~ connectomics. You gotta have enough resolution to see the important things. 2nm/px FTW!
A ultrastructural image at 2nm/pixel of a cross section of a cilia.
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Andreas Müller @andimicroscopy.bsky.social · 10/07/2026
Happy to share our review on islet ultrastructure @diabetologiajnl.bsky.social: link.springer.com/article/10.1... We cover classical EM, multimodal, and3D imaging and give an outlook on exciting future experiments on islet structure in diabetes. @plid-info.bsky.social @hhmijanelia.bsky.social
link.springer.com
Islet ultrastructure: past achievements and future directions - Diabetologia
Islets of Langerhans constitute the endocrine component of the pancreas and comprise the main cell types responsible for the regulation of glucose homeostasis. Beta cells produce and secrete insulin, ...
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Andreas Müller @andimicroscopy.bsky.social · 10/07/2026
Amazing! Congratulations!
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Helmholtz Imaging @helmholtzimaging.bsky.social · 09/07/2026
How ready is your image dataset for analysis? Join our 2-part online workshop on image dataset quality control, data exploration and PixelPatrol. 📅 Sept 10 + 17, 2026 Open to @helmholtz.de & HIDA partners Registration opens Aug 13, 12 PM. More 👉 bit.ly/Image-Qualit... #datascience #training
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Spagnoli_Lab. @labspagnoli.bsky.social · 04/07/2026
🚨We are #hiring! Excited to welcome a talented #postdoc to join the lab. and be part of an interdisciplinary research program #Type1DiabetesGrandChallenge -- harnessing #pancreas #development for #stem cell therapy of #diabetes. 🧫🧪🔬 Join us! Apply before 23 July. ⤵️ my.corehr.com/pls/coreport...
Images Human Pancreas Organoids
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Ben Engel @cellarchlab.com · 03/07/2026
Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩‍🔬👨‍🔬
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EMBO @embo.org · 30/06/2026
Gain #training on correlative #LightElectronMicroscopy techniques in the eponymous EMBO Practical Course "Correlative light electron microscopy" in Utrecht, Netherlands, 13–18 September 2026. Deadline: 3 July 2026 meetings.embo.org/event/26-clem #EMBOCorrelativeLight #EMBOevents 🧪
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Christophe 🔬 Leterrier @christlet.bsky.social · 28/06/2026
Look at that dinosaur reading and reviewing claims himself rather than asking Claude how good it is, as we all know now proper independent review should be done /s
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Stephen Royle @steveroyle.bsky.social · 25/06/2026
This AI stuff.... Anyone else feel like they're one of the remaining unbitten characters in a zombie movie?
Mastodon post that says: I feel like I'm one of the remaining unbitten characters in a zombie movie.

In the past week:
- marked student papers with clear LLM use
- attended student hearing for academic integrity due to LLM use
- received peer review comments that seemed AI generated
- important email from a colleague that was riddled with banal LinkedIn-ese and must also be LLM-generated

This post is human-created!
#IsThereAnybodyOutThere #AIApocalypse
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Harmit Singh Malik @harmitmalik.bsky.social · 24/06/2026
I know it seems like a heretical idea, but one way to figure out if a preprint is really interesting (to you) is... to read the preprint. Then, in the spirit of sharing, send a note to authors: a simple kudos or a more detailed question. I do this a dozen times a year. It's awesome. Try it.
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Wieczorek Lab @mike-wieczorek.bsky.social · 23/06/2026
New preprint! In collaboration with the Steinmetz Lab at PSI we report cryo-EM structures of microtubules at up to 1.9 Å (!) resolution & in different nucleotide state mimics, suggesting a mechanism for lattice-induced GTP hydrolysis and why it leads to catastrophe: tinyurl.com/7cjrf863
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Mel Andrews @bayesianboy.bsky.social · 17/06/2026
When utilized in literature review, LLMs consistently 1. fail to mention female authors in female-led literatures, 2. insist that men are more influential or more heavily cited when this is contradicted by objective citation counts, and 3. attribute women’s work to hallucinated male scholars.
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Biohub @biohub.org · 16/06/2026
Cryo-ET gives unparalleled views of cellular structures, but targeted sample preparation by cryo-FIB milling has been a constraint. No longer! A new workflow yields close to 100% targeting success for centrioles & other small structures. Read the preprint ⤵️ www.biorxiv.org/content/10.6...
Diagram of FIB-SEM with integrated fluorescence microscope alongside cryo lamella micrograph and 3D segmentation highlighting targeted centrioles
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Andreas Müller @andimicroscopy.bsky.social · 17/06/2026
I am scared to check things like the references
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