By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University

Summary: A guide to mechanics in development: unlock how forces, material properties and geometry shape the forms of life.

I’m taking part in One Walk London on 2026-06-20 for Breakthrough T1D! Please support me with my challenge and give whatever you can spare. Breakthrough T1D's research has led to amazing developments ...

Jia et al. develop SPACE-seq, a versatile technology that integrates CRISPR barcoding with spatial transcriptomics to jointly map cell ancestry, identity, and location. Compatible with diverse spatial platforms, SPACE-seq can be applied to a wide range of biological questions, revealing clonal architecture, migration, and fate-shaping interactions in development and cancer.

Brassard and Wells discuss how next-generation human pluripotent stem cell-derived organoids are achieving greater cellular complexity by more faithfully reproducing developmental processes. Advances in tissue interactions, specialized cell incorporation, and bioengineering technologies are enabling increasingly physiologically relevant organoid models to study human development, disease mechanisms, and regenerative biology.

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Nature Reviews Gastroenterology & Hepatology - Pancreatic development is a dynamic process. This Review discusses the development and cellular plasticity that occurs in the pancreas in health...

Nature Reviews Gastroenterology & Hepatology - Pancreatic development is a dynamic process. This Review discusses the development and cellular plasticity that occurs in the pancreas in health...

Nature Reviews Gastroenterology & Hepatology - Pancreatic development is a dynamic process. This Review discusses the development and cellular plasticity that occurs in the pancreas in health...

Summary: This Development at a Glance article summarizes current research into the cellular and molecular mechanisms controlling the development of the vertebrate embryonic endoderm into digestive and...

Summary: This Review examines the evolutionary history of the extra-embryonic endoderm, an evolutionarily ancient tissue co-opted to form the yolk sac, and explores how in vitro models are uncovering ...

Gail Roberta Martin, Professor Emerita of Anatomy at the University of California, San Francisco, and one of the founding figures of modern stem ce...

The 2027 Gordon Research Conference on Pancreatic Diseases will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

I'm taking on Swim22 and raising money for Diabetes UK

Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leig…