Nucleotide-binding and oligomerisation domain-like receptors (NLRs) are famous for driving immune responses in plants and animals. However, their extensive presence in multicellular…

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Taillefer et al. show that a bacterial type VI secretion system is lost or attenuated during experimental evolution when it provides no competitive advantage but is maintained in the presence of susce...

Nature Reviews Microbiology, Published online: 08 May 2026; doi:10.1038/s41579-026-01299-7In this Review, Vasse and Velicer explore the phylogenetic and functional diversity of predators of microorganisms, conceptualizing the forms of microbial predation along gradients, including gradients of evolutionary adaptedness for predation and privatization of prey-derived nutrients.

Institut Pasteur and the CNRS are launching a joint call for a mid-career group leader position in Medicinal Chemistry and Chemistry for Health. We are looking for an experienced researcher (typically...

EMBL Hamburg / CSSB The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organization, with more than 110 independent research groups across Heidelberg, Hamburg, Grenobl...

Pour Paula Navarro, les secrets du vivant se cachent à l’échelle atomique. Pour explorer cet univers minuscule, la biologiste s’appuie sur la cryo-microscopie électronique. Et s’il y a un endroit où p...

Conjugative plasmids are a class of mobile genetic elements capable of efficient transfer between bacterial cells. Although they can introduce beneficial traits such as antibiotic resistance to recipi...

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The Sec translocon and the YidC/Oxa1-type insertases universally mediate biogenesis of α-helical membrane proteins, but the molecular basis of their cooperation has remained disputed. Recent discovery...

ALT: Happy Dance

Contractile injection systems (CISs) are nanomachines that inject proteins into target cells. Here, the authors resolve the atomic structure of a CIS in the opportunistic human pathogen Salmonella ent...

Phase plates can in principle overcome the poor image contrast in electron cryo–microscopy (cryo-EM) and the resulting limits on the structural reconstruction of small proteins. However, previous desi...

Unnecessary bureaucracy is a global impediment to progress and productivity that increases stress and lowers workplace morale and motivation. In research it smothers creativity and innovation that ar....

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.