iiinova — where your digital self keeps evolving

Microbial Biotechnology (MBT) @microbiotech.bsky.social · 30/09/2026

#MicroSky: Xu et al. report that washed microbiota transplantation (WMT) showed promising feasibility & safety as salvage therapy for refractory non-CDI gut infections in critically ill patients, with 50% achieving clinical cure & no serious WMT-related adverse events. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 28/09/2026

#MicroSky: Can eye microbes help combat myopia? Yanqing Li et al. show that Lactobacillus mucosae MM-1 and its metabolite indole-3-lactic acid reduced lens-induced myopia in mice via AHR activation and TGF-β/Smad inhibition. Advancing science! doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 25/09/2026

#MicroSky: Barcelos et al. explore how biomanufacturing can scale from lab to industry, converting waste carbon into biofuels, biochemicals, and biomaterials. Integrating biology, process engineering, modelling, and economics is key to a sustainable bioeconomy. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 23/09/2026

#MicroSky: Li et al. uncover how indigenous fungi from mine tailings oxidize pyrite through distinct mechanisms, from organic acid secretion to peroxidase-driven pathways. A step forward for bioleaching and mining biotechnology. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 21/09/2026

#MicroSky: GUT MICROBIOME: Zhang et al. report that Bifidobacterium animalis subsp. lactis CP-9 safely enriched beneficial Bifidobacterium in healthy infants and improved gut tolerability over 3 months. Find more on Probiotics at doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 18/09/2026

#MicroSky: CIRCULAR ECONOMY: Laura de Eugenio et al discuss that enzymes can help tackle plastic waste, but no single technology will deliver circularity alone. A systems approach to plastics & bioplastics is key. Find their OPINION at doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 16/09/2026

#MicroSky: ANTI-PHAGE: Bacteria deploy remarkably diverse defenses against viruses, from DNA injection blockers and nucleases to immune-like systems resembling gasdermins, Argonautes and ubiquitin pathways. Thousands of anti-phage systems remain to be discovered. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 14/09/2026

#MicroSky: GREEN TECH. TolC is a key missing piece in mixed-linkage β-glucan (MLG) biosynthesis. Engineering Sinorhizobium meliloti with tolC, bgsBA and pleD boosted MLG production up to ~10 g/L and enabled synthesis in new bacterial hosts. Find more in Ruiz-Suarez et al., doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 11/09/2026

#MicroSky: METABOLISM. In vivo catalytic rates of 99 enzymes in formate-grown Methanococcus maripaludis reveal weak agreement with sequence-predicted turnover numbers, highlighting low enzyme saturation as a key constraint in C1 metabolism and bioengineering. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 07/09/2026

#MicroSky: SYNTHETIC BIOLOGY: Can we predict quorum sensing behaviour? A validated mathematical model helps fine-tune EsaI/EsaR genetic circuits, accelerating synthetic biology design. Relevant advances by De Baets et al. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 03/09/2026

#MicroSky: MORE THAN POLLINATORS: Honey bee gut microbes may be an overlooked detox organ. A new perspective proposes harnessing the microbiome to protect pollinators from pesticide exposure. Read the Opinion article by Liu et al. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 01/09/2026

#MicroSky: GLYCOBIOLOGY. Sugar matters! Optimizing N-glycosylation doubled the production of a fungal peroxygenase in yeast, improving recombinant enzyme yields for industrial biotechnology. Very relevant research presented by Schramm et al. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 27/08/2026

#MicroSky: FERMENTATION: Scaling up antifungal protein production is becoming a reality. Optimized bioreactor conditions boosted PeAfpA yields tenfold, paving the way for sustainable biofungicides. Find more in De Ovalle et al. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 24/08/2026

#MicroSky: PHYTOREMEDIATION: Can plants help clean up toxic pesticides? Engineered Arabidopsis expressing a bacterial dechlorinase removed >90% of lindane in just 4 weeks, opening new avenues for soil bioremediation. Learn more: Gonzalez De Figueras et al. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 20/08/2026

#MicroSky: Mycosynthesized silver nanoparticles show promise as safe, biocompatible vaccine adjuvants, boosting immune responses with strong dose-dependent IgG2a polarization, minimal toxicity and limited gut microbiota disruption in mice. Exciting work by Muñiz-Lago et al at doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 17/08/2026

#Microsky:Zeng et al present the first report of a clinical monophasic Salmonella Typhimurium ST34 with chromosomally integrated blaNDM-5. This stable carbapenem-resistant high-risk clone highlights the key role of IS26 in resistance spread & the need for genomic surveillance doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 13/08/2026

#MicroSky: Antibiotics. Xu et al present CI-ARS3, a dual-silencing platform that suppresses streptomycin and streptothricin biosynthesis by >97% in Streptomyces, enabling discovery of hidden antimicrobials, including the new compound enissomycin active against A. baumannii. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 10/08/2026

#MicroSky: Did you know? Popelarova et al. show that outer membrane porins can shape sugar uptake in Pseudomonas putida. Engineering OprB-I improved glucose and xylose utilization, highlighting an overlooked strategy for metabolic engineering and synthetic biology. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 06/08/2026

#MicroSky: Biocontrol: Zhang et al. uncover how GATA transcription factors coordinate pathogenicity and chlamydospore formation in the nematode-trapping fungus Arthrobotrys. WC2 emerges as a promising engineering target for improved biocontrol strains. Don’t miss at doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 03/08/2026

#MicroSky: High-copy expression can overwhelm the ER—but shi et al found a way forward. In Komagataella phaffii, engineering key UPR regulators boosted secretion of recombinant proteins by up to 46%, advancing a more robust chassis for Synthetic Biology and biomanufacturing. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 30/07/2026

#MicroSky: Synthetic biology toolbox expansion for probiotic Lacticaseibacillus rhamnosus. Direct plasmid cloning, a strong promoter, and engineering fluorescent strains, open new chances for studying host–microbe interactions and developing probiotic cell factories. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 27/07/2026

#MicroSky: Pseudomonas KT2440 grows on polyethylene-derived long-chain alcohols, and adaptive evolution rapidly boosts this ability. Expressing the outer-membrane transporter AlkL shows membrane permeability as a key lever for engineering microbes to upcycle plastics. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 23/07/2026

#MicroSky: Fungal metabolism: Deleting NADPH dehydrogenase genes in Podospora reshapes fungal metabolism: boost fruiting body formation, alter redox balance, increase oxidative stress sensitivity, and rewire energy and lipid metabolism. By Qiu et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 20/07/2026

#MicroSky: A heterologous T3SS transforms P. protegens Pf-5 into a programmable molecular syringe, delivering Bg9562 into Fusarium hyphae to suppress disease, boost rhizosphere colonization, & protect tomato plants from wilt. A promising modular platform for fungal biocontrol doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 16/07/2026

#MicroSky: 5-year journey of IMiLI-SAC in advancing Microbiology Literacy & translating Microbiome science into society. Through outreach, multilingual resources & education, we connect microbes with health, sustainability, etc.: building an informed & healthier future. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 13/07/2026

#MicroSky: PLANT/MICROBES INTERACTIONS. Plants and microbes communicate in unexpected ways. Soybean flavonoids trigger the formation of wall-deficient cells in Streptomyces, revealing a link between plant metabolites and bacterial morphology. Learn on biotech applications at. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 09/07/2026

#MicroSky: SYNTHETIC BIOLOGY. How do microbes respond to electricity? Al Sbei et al show that microbial electrosynthesis drives Clostridium ljungdahlii into a unique physiological sate, offering new insights into carbon capture, energy storage and biomanufacturing. Don’t miss doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 06/07/2026

#MicroSky: Cancer Research: Microbial genetics can transform cancer diagnostic. Xi et al identified thousands of E. coli SNOs associated with colorectal cancer, enabling a highly accurate, non-invasive risk prediction model. Don’t miss doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 03/07/2026

#MicroSky: PLANT HEALTH: Can bacteriophages protect oak trees? Grace et al doi.org/10.1111/1751... isolated the first phages targeting bacteria linked to acute oak decline. While promising in the lab, field assays highlight the complexity of applying phage therapy in natural environments.

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 01/07/2026

#MicrosKY: VACCINES: A new nanoparticle vaccine platform against West Nile virus shows strong immune responses, scalability and safety. Built on bacterial expression systems, the novel approach can accelerate affordable vaccine development against multiple viruses. Byun et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 29/06/2026

#MicroSky: Scientific academies are more than honor societies; they are public institutions with a responsibility to lead. In an era of climate change, inequality, declining trust in science, evidence-based leadership has never been so important. Timmis et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 24/06/2026

#MicroSky: From Antarctica comes a new discovery by Kralova et al doi.org/10.1111/1751.... They identified kineochelins, an unknown group of siderophores produced by rare actinomycetes. A new step toward uncovering new bioactive compounds and antimicrobials.

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 23/06/2026

#MicroSky: MBT has achieved a CiteScore of 9.4! We’re thrilled to rank in the top 15% of the areas of Applied Microbiol & Biotechnol and Biochemistry, Genetics & Mol Biol. THANKS to our readers, authors, staff & editors for their unwavering support!

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 22/06/2026

#MicroSky: SCIENCE COMMUNICATION: Microbes shape our world, yet they are often misunderstood. Bakteriopolis is bringing the hidden microbial world directly to communities through interactive exhibits, hands-on activities and dialogue with scientists. Read Friebel et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 19/06/2026

#MicroSky: ONE HEALTH: Cutibacterium acnes extracellular vesicles promote ovarian tumor growth by activating the KEAP1–NRF2 axis and suppressing ferroptosis. RSL3 reversed these effects, highlighting microbial EVs therapeutic targets in EOC. Learn more. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 17/06/2026

#MicroSky: BIOREMEDIATION In the environment, bacteria sense aromatic pollutants, move to them, adapt to toxicity, & use specialized uptake & catabolic systems. Genomic plasticity, metabolic versatility & division of labor within populations aid to remove persistent chemicals doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 15/06/2026

#MicroSky: Kim et al (doi.org/10.1111/1751...) improved microbial chemical production by combining genomic libraries with fluorescent biosensors. They identified genes involved in 3-HP import & locking product re-uptake boosted 3-HP titers by 21%, advancing smarter microbial cell factories.

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 12/06/2026

#MicroSky: SYNTHETIC BIOLOGY. Kato et al (doi.org/10.1111/1751...) engineering bacterial P450 into an H₂O₂-driven biocatalyst boosting activity 28-fold & enabled efficient synthesis of valuable compounds, including indigo dye. A simple, powerful strategy to expand sustainable enzyme-driven chemistry

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 10/06/2026

#MicroSky: Machine learning meets microbiome science: optimized amino acid formulations for Bifidobacterium longum reduced nutrient inputs by up to 77% while maintaining growth. Kaneco et al reveal key amino acids shaping fitness and enables streamlined media design. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 08/06/2026

#MicroSky: Science conversations are evolving. By analysing interactions on X and BlueSky, Bernal et al highlight the microbiology and biotechnology topics our community cares about most: from precision medicine to synthetic biology and sustainability. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 05/06/2026

#MicroSky: Park et al present ways for fighting antibiotic resistance by targeting bacterial persisters. bymBDZ accelerates persister regrowth & increases antibiotic susceptibility in E. coli, boosting killing during early recovery. A promising strategy to prevent relapse. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 03/06/2026

#MicroSky: A greener future for bioplastics: near-solvent-free recovery of microbial PHAs directly from wet biomass using insect-derived enzymes. High polymer recovery & material quality, & up to 7× lower carbon footprint without drying or toxic solvents. Read Bogojevic et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 01/06/2026

#MicroSky: GREEN CHEMISTRY: Succinic acid is key for sustainable green chemistry, but cost & sustainability challenges limit scale-up. Gunkel and Blombach explore next-generation feedstocks, low-pH fermentations & novel yeasts to advance competitive succinic acid production. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 29/05/2026

#MicroSky: Adapting Bacteria for Better Bioremediation. Evolving Dehalobacter on mixed substrates boosts 1,1-DCA dechlorination. Key mutations in TmrA enhance binding to xenobiotic pollutants, a new path to engineer more efficient cleanup microbes. Read Ren et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 27/05/2026

#MicroSky: Engineering Better Fucosylation with Enzyme Design. MBT ( doi.org/10.1111/1751...) presents a study led by Patricie Vodičková, that boosts transfucosylation >20× via a single mutation (S237V), enabling precise synthesis of fucosyllactose derivatives for biosensors and diagnostics.

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 25/05/2026

#MicroSky: Better Biosensors: Engineering Geobacter biofilms via cGAMP signaling enhances electron transfer, creating thinner, more conductive films. Result: a 20× improvement in Cd(II) detection sensitivity, hence advancing bioenergy and biosensing tech. By Zhang , Han et al doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 21/05/2026

#MicroSky: Wastewater: Prototheca, rare pathogenic microalgae, are widespread in wastewater (78% samples). Treatment cuts levels by up to 99.9%, yet detectable cells remain, highlighting WWTPs as potential release routes & the need for routine monitoring + safety guidelines. doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 20/05/2026

#MicroSky: Healthcare systems are failing on access, equity, and resilience. Timmis et al propose a bold reset: patient-driven digital care, microbial tech innovation, and a shift to prevention, reframing healthcare as a public good, not a commodity. Learn more doi.org/10.1111/1751...

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Microbial Biotechnology (MBT) @microbiotech.bsky.social · 18/05/2026

#MicroSky: How does a methylotrophic yeast fine-tune methanol metabolism? Cai et al reveal high-res structures of two alcohol oxidase isozymes in Ogataea methanolica, showing distinct cofactor preferences & assembly into functional octamers: biotech protein production. doi.org/10.1111/1751...

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