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Olaya Rendueles

@olayarendueles.bsky.social
2K followers 702 following 239 posts

Microbial evolution & ecology, focus on surface structures (capsules) and HGT (#plasmids #phages), mostly in #Klebsiella #MicroSky From #Asturias 🇪🇸 living in 🇫🇷 @CNRS

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Reposted by Olaya Rendueles
Salim T. Islam Research Group @islamyxolab.bsky.social · 29/09/2026
Turns out (i) myxospores are actually coated in exopolysaccharide (making them sticky!), (ii) biosurfactant polysaccharide is needed to help them disperse, and (iii) spore "coat" polysaccharide instead forms a sub-surface cortex layer!🦠🔬 www.biorxiv.org/content/10.6...
biorxiv.org
Biosurfactant polysaccharide drives dispersal of exopolysaccharide-coated myxospores in Myxococcus xanthus
Bacterial spores are highly resilient cell forms, yet the organization of their protective surface layers in diderm species remains largely unexplored. For the social predatory soil bacterium Myxococc...
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Olaya Rendueles @olayarendueles.bsky.social · 11/09/2026
Excellent read! Much needed perspective. 💯% recommended
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Meaghan Castledine @mcastd.bsky.social · 10/09/2026
🦠Fully funded PhD project with myself, Angus Buckling, Jo Lello and Phil Mitchelmore🦠 How should we design phage therapeutics for bacterial co-infections? How do interactions between pathogens affect treatment efficacy? Please get in touch if you have any Qs 💃 shorturl.at/39Xea
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Max-Planck-Gesellschaft @maxplanck.de · 09/09/2026
We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack
Call for independent Max Planck Research Groups
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Olaya Rendueles @olayarendueles.bsky.social · 08/09/2026
Feliz día de Asturias 💙💚💙 #AsturiasParaisoNatural Home sweet home
Asturias pic
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Olaya Rendueles @olayarendueles.bsky.social · 03/09/2026
An icon. A pioneer. An inspiring, courageous voice who changed the world and made it better for generations of women and so many others. Gloria Steinem leaves an extraordinary legacy. www.nytimes.com/2026/09/03/u...
nytimes.com
Gloria Steinem, Personification of the Feminist Movement, Dies at 92
She challenged sexist assumptions, helping women develop a sense of self-worth and gain a measure of equality at work, at home and in society at large.
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Reposted by Olaya Rendueles
Casey Dunn @caseywdunn.bsky.social · 25/08/2026
My new book, Phylogenetic Biology, is now published. Available online for free at dunnlab.org/phylogenetic... . Physical copies can be purchased at shop.lightningsource.com/b/085?params... or your favorite bookstore.
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QinQin Yu @qinqinyu.bsky.social · 19/08/2026
Some bacteria can rapidly change their surface proteins to undergo antigenic variation – what is the diversity of these proteins and how do they evolve? We delved into this question in Neisseria gonorrhoeae, the cause of the sexually transmitted infection gonorrhea: journals.plos.org/plospathogen...
journals.plos.org
Diversity and evolution of a phase-variable multi-locus antigen in Neisseria gonorrhoeae
Author summary The rising levels of antibiotic resistance in Neisseria gonorrhoeae make controlling the spread of this sexually transmitted pathogen a public health priority. N. gonorrhoeae rapidly va...
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 18/08/2026
Functional profiling of ESKAPE viromes uncovers resistance-limiting phage-host dynamics www.biorxiv.org/content/10.64898/20…
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Olaya Rendueles @olayarendueles.bsky.social · 20/07/2026
There are few threads left to hold everything together in #Spain, and soccer is one of them. Tomorrow, all seams will burst open. But today,at least today,let’s enjoy and just be happy for a while. #WorldCup And #Trump has the nerve to say that we don’t invest in defense in Spain 🤣 VAMOOOOS 🇪🇸 !
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Olaya Rendueles @olayarendueles.bsky.social · 26/06/2026
@klebclub.bsky.social check this out!
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Reposted by Olaya Rendueles
brunolemaitre.bsky.social @brunolemaitre.bsky.social · 17/06/2026
A short, informal intro to Drosophila genetics (with a French accent 🇫🇷): key concepts & techniques for new lab members. www.epfl.ch/labs/lemaitr...
epfl.ch
Short Introduction to Drosophila_Engl
If you like French accent:A short and informal introduction to Drosophila genetics, covering the basic knowledge and techniques that may be helpful when working with Drosophila. This series of short l...
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Olaya Rendueles @olayarendueles.bsky.social · 15/06/2026
@klebpapers.bsky.social @klebclub.bsky.social
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Toni Gabaldón @tonigabaldon.bsky.social · 10/06/2026
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
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Ken Timmis @kentimmis.bsky.social · 01/06/2026
Unnecessary bureaucracy is a global crisis impeding productivity, advancement of human and planetary wellbeing, science and sustainability. This self-inflicted problem urgently needs solution through global efforts at all levels. doi.org/10.1111/1751...
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Olaya Rendueles @olayarendueles.bsky.social · 01/06/2026
An excellent resource for @klebclub.bsky.social & #phagesky!
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Olaya Rendueles @olayarendueles.bsky.social · 01/06/2026
🌟 Very proud of the newest Dr. in the team , Dr. @julielebris.bsky.social 👩‍🎓! She brilliantly defended her PhD last Friday @pasteur.fr Excellent thesis in terms of output & quality! Thanks to the jury @lucyweinert.bsky.social @sylvainbrisse.bsky.social @edfeil.bsky.social Maria Halima Laaberki
The big moment
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Reposted by Olaya Rendueles
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 28/05/2026
Pervasive bacterial and prophage hybridization during chronic gut inflammation www.biorxiv.org/content/10.64898/20…
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Reposted by Olaya Rendueles
Yunn-Hwen Gan @yunnhwengan.bsky.social · 25/05/2026
If you are interested in hypervirulent #Klebsiella pneumoniae and liver abscess, pls take a look at our short review on Host interactions of hvKp along the gut liver axis! #microsky #UTIsky authors.elsevier.com/sd/article/S...
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Olaya Rendueles @olayarendueles.bsky.social · 24/05/2026
Se acabó el sueño del centenario. El #RealOviedo 💙🤍 ya no es de Primera 😔 Pero qué año hemos vivido, en los mejores campos, despidiendo a #Cazorla a lo grande Gracias a la afición vasca por recibirnos como hermanos. Volver a La Catedral fue algo inolvidable. Volvimos… y volveremos. 💙 #HalaOviedo
Bandera del oviedoCazorla se despide
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Olaya Rendueles @olayarendueles.bsky.social · 19/05/2026
🔬🦠 Comment #Klebsiella parvient-elle à changer de capsule aussi fréquemment pour mieux s’adapter à son environnement ? Les travaux de @julielebris.bsky.social mis à la une par @cnrsbiologie.bsky.social 👏 -avec @epcrocha.bsky.social #MicroSky @cbitoulouse.bsky.social
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CNRS Biologie @cnrsbiologie.bsky.social · 19/05/2026
#ResultatScientifique🔎| Une bactérie capable de changer de « bouclier » pour mieux s’adapter à son environnement : une stratégie étonnante de Klebsiella pneumoniae qui éclaire ses capacités d’évolution et de résistance. ✍️ @olayarendueles.bsky.social @julielebris.bsky.social ▶️ buff.ly/q8AKHo1
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Prof. Ruth Ley FRS @microbiome.bsky.social · 03/05/2026
Come and work with us in a beautiful corner of Germany: 5 years of funding for your microbiology research and lots of great colleagues 🦠🧫
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Clara Torres-Barceló @clara-inrae.bsky.social · 29/04/2026
🚨 We’re looking for a PhD student to join @phimresearch.bsky.social and explore phages in emerging rice epidemics 🌾 We will investigate phage–bacteria interactions and the seed microbiome/phageome. #phd #phage #plantscience #microbiome #scijobs ‪ 👉 More info: tinyurl.com/yhc2fa7
filesender.renater.fr
FileSender
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Klebsiella Club @klebclub.bsky.social · 23/04/2026
TODAY!! Join us for Session 3 of #KlebClub2026 📅 April 23rd ⏰ 9:00–10:30 AM EDT 🔬 Theme: Translational Microbiology Hear from researchers bridging bench to bedside and explore innovative approaches to tackling Klebsiella pneumoniae. ✨ Free registration ->scan the QR code on poster
klebclub flier
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Fernando Gonzalez-Candelas @fgonzalef.bsky.social · 22/04/2026
We are hiring a PhD candidate! Only for non-EU graduates. To work on the molecular and genomic epidemiology of Treponema pallidum, based on our recent publication (doi:10.1128/mbio.00358-26). Interested? Send your CV and an expression of interest to fernando.gonzalez@uv.es before May 20th, 2026.
uv.es
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Klebsiella Club @klebclub.bsky.social · 03/04/2026
‼️ Excited to announce 1st session of #KlebClub2026! We kick things off with a session on pathogenesis, with *Jay Vornhagen* as keynote speaker, alongside 2 short talks selected from submitted abstracts - Sylvie MIQUEL & @microbiosaroj.bsky.social 🗓 Thursday 9 🕘 9:00 -10:30 AM (EDT) (1/2)
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Tatiana Dimitriu @tatianadimitriu.bsky.social · 02/04/2026
And the preprint is out! www.biorxiv.org/content/10.6... We compared plasmid conjugation in liquid and on solid across 13 AMR plasmids with different types of conjugative pili.
biorxiv.org
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Daniel Padfield @padpadpadpad.bsky.social · 30/03/2026
PLEASE SHARE. PhD Opportunity with me, Ben Raymond and Jan Engelstaedter and Andrew Letten at University of Queensland. Experimentally testing mechanisms of how temperature may change selection and spread of AMR in E. coli. Coupled with some advanced modelling and sequencing. 🧪🦠 #microsky
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Olaya Rendueles @olayarendueles.bsky.social · 27/03/2026
Our latest manuscript explores capsule exchangeability & phenotypic portability We didn’t directly address its role in #virulence ⏩️ that was already elegantly shown here—worth a look 👀👇🏻 doi.org/10.1371/jour... 🎯 Their results supports our plug-and-play model! Bonus: we kept 🐭 alive #microsky
doi.org
Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver
Author summary Klebsiella pneumoniae is a major human pathogen. While capsule is the main virulence factor of the pathogen, only several of more than 80 capsule serotypes are frequently identified in ...
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Reposted by Olaya Rendueles
PLOS Biology @plosbiology.org · 26/03/2026
How do multi-gene systems evolve across genetic backgrounds without disruptive epistasis? @julielebris.bsky.social @olayarendueles.bsky.social &co show the #Klebsiella capsule locus is a plug&play module that swaps with low fitness cost while preserving #virulence @plosbiology.org 🧪 plos.io/4s64Ko0
Characteristics and capsule production of capsule-swapped strains. Genetic (lower triangle) and biochemical (upper triangle) relatedness between the different capsule types analyzed in this study. Biochemical similarity was calculated as the percentage of residues shared between two K types (# of shared unique oligosaccharides/# of different nonredundant oligosaccharides). Oligosaccharidic compositions and models were taken from K-PAM. Genetic relatedness was calculated taking into account all homologous genes between two K types. Monosaccharides composing the different capsules are depicted according to the Symbol Nomenclature for Glycans convention.
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Olaya Rendueles @olayarendueles.bsky.social · 26/03/2026
So happy to see this finally published in @plosbiology.org! This is the first chapter of @julielebris.bsky.social PhD thesis demonstrating how capsules are exchanged by plug-and-play dynamics w/ @epcrocha.bsky.social #microsky @klebclub.bsky.social Link below- Check out her 🧵 for more details!
doi.org
Plug-and-play evolution of the Klebsiella pneumoniae capsule locus enables serotype exchange across genetic backgrounds
How complex multi-gene systems evolve across genetic backgrounds without disruptive epistasis remains unclear, particularly in highly exchangeable loci such as the capsule of Klebsiella pneumoniae. Th...
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Eduardo Rocha @epcrocha.bsky.social · 17/03/2026
Horizontal gene transfer is often depicted as a process distributing pre-existing functions to novel genetic backgrounds. Yet HGT can also increase the rate of functional innovation after transfer. Here's a brief review on the topic: ecoevorxiv.org/repository/v... #evosky #microsky
ecoevorxiv.org
From Trading Genes to Crafting New Tricks: How Horizontal Gene Transfer Potentiates the Emergence of Novel Functions
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 15/03/2026
Cross-family and phage-specific gene requirements for Klebsiella infection revealed by scalable RB-TnSeq genetic screens www.biorxiv.org/content/10.64898/20…
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Alvaro San Millan @sanmillan.bsky.social · 13/03/2026
Final version of our last paper is out! www.nature.com/articles/s41...
nature.com
Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation - Nature Microbiology
Inactivation of chromosomal genes through plasmid-encoded IS elements is an extended mechanism of antimicrobial resistance evolution in bacteria.
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Sara Mitri @saramitri.bsky.social · 09/03/2026
This! 👇
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Tobias Warnecke @tobiaswarnecke.bsky.social · 05/03/2026
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you! 1/n
my.corehr.com
Job Details
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Microbiology Society @microbiologysociety.org · 05/03/2026
#OnThisDay in 1938, American evolutionary biologist Lynn Margulis was born. Margulis is most known for developing and popularising the endosymbiotic theory, which explains how eukaryotic cells evolved organelles from simpler prokaryotic organisms that resided within another and became incorporated.
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Pedro Dorado-Morales @doradomoralesp.bsky.social · 26/02/2026
New preprint out on bioRxiv! www.biorxiv.org/content/10.6... Can conjugative plasmids be used to control plasmid and pathogen spread? Follow me down the rabbit hole that led to this story 🧵
biorxiv.org
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Richard Lenski @relenski.bsky.social · 21/02/2026
Alita Burmeister (@aburmeister.bsky.social) is looking to hire a postdoc (or potentially a PhD student) for projects on phage resistance and evolution. The position description is posted to the Eco-Evo Jobs wiki and also available on her lab's website (arburmeister.weebly.com).
arburmeister.weebly.com
The Burmeister Lab: Studying Microbial Evolution and Extinction
​Our research integrates evolutionary biology and microbiology, using bacteria and phage as study systems to address fundamental questions in both fields. ​ ​We study microbial evolution, a...
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Zaki Saati-Santamaría @zakisaati.bsky.social · 17/02/2026
How do evolutionary forces shape bacterial adaptation to the plant environment? 🌱🦠 Curious? Read our new review in @femsjournals.bsky.social Microbiology Reviews. #PlantMicrobiome #MicrobialEvolution #HostMicrobeInteractions #Rhizosphere #Microbiome 🔗 doi.org/10.1093/fems...
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FEMS @femsmicro.org · 19/02/2026
💡 We are inviting you to nominate a woman in microbiology whose work or impact deserves to be seen. Selected nominations will be featured on the FEMS website and across our social media channels on International Women’s Day, 8 March. 👉 Who inspires you? Nominate them by 4 March . buff.ly/AKyMbQD
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Klebsiella Papers @klebpapers.bsky.social · 19/02/2026
Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor-Binding Protein Mining and Modular Assembly doi.org/10.1002/advs.202514511
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Francois Lebreton @flebreton.bsky.social · 18/02/2026
New preprint out! Anjali Sapre, Melissa Martin and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. www.researchsquare.com/article/rs-8...
researchsquare.com
Preferred evolutionary routes of convergence in Klebsiella pneumoniae favor siderophore acquisition over hypervirulence
The rise of Klebsiella pneumoniae combining antimicrobial resistance and virulence genes poses a major health threat, but the evolutionary routes and phenotypic consequences of this convergence are po...
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 13/02/2026
New in JB: Weiss, Tamayo et al. describe a very cool microbial interaction wherein Enterococcus faecalis, an opportunist found in the inflamed gut, impacts phase-variation noted by chaining & rough colony morphology of C. diff. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
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Rubin Lab @therubinlab.bsky.social · 12/02/2026
Check out our latest preprint from @jnvmartinson.bsky.social and @leosong.bsky.social! 🌟🦠 We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
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Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 13/02/2026
Please check out our review on the impact of spatial structure in microbial ecosystems! In it, we discuss how spatial patterns impact microbial ecology and evolution, eventually impacting everything we see around us! See @marcelbaecker.bsky.social's amazing summary below :) 🦠 𝚂𝙿𝙰𝙲𝙴 𝙼𝙰𝚃𝚃𝙴𝚁𝚂 ! 🦠
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Olaya Rendueles @olayarendueles.bsky.social · 09/02/2026
#PhageSky
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Laura Mike @lauraamike.bsky.social · 09/02/2026
✨If you have a story you would like to share with the community, please submit an abstract by Feb 16. ✨
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Olaya Rendueles @olayarendueles.bsky.social · 03/02/2026
Today we were thrilled to host @tatianadimitriu.bsky.social at @cbitoulouse.bsky.social @cnrsbiologie.bsky.social She discussed factors contributing to plasmid spread (defense systems, environmental factors…) - with @benoitjpons.bsky.social
Hosting of Tatiana’s scientific talk  @ CBI touliuse
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