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Valentin Riedl

@vavatin.bsky.social
1.8K followers 671 following 74 posts

Brain scientist asking: How do we spend metabolic energy on processing information? 
valentinriedl.de
 | Professor for multiscale neuroimaging @FAU
 | NeuroEnergetics-lab @TUM
 | Award-winning documentary LOST IN FACE about Carlotta and her brain

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Reposted by Valentin Riedl
Gabriel Castrillon @gabocas.bsky.social · 17/07/2026
Special thanks to Pietro Marcolongo, Urmi Bhattacharyya, @samomat.bsky.social , Dr. Antonia Bose, Dr. Stephan Kaczmarz, Gabriel Hoffmann, Daniel Rueckert & @vavatin.bsky.social #Neuroimaging #MRI #SciComm @fau.de @akmaier.bsky.social
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Valentin Riedl @vavatin.bsky.social · 24/06/2026
Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Naomi Klein @naomiaklein.bsky.social · 02/07/2026
Everybody in the "climate space" (which means everyone on earth...) needs to understand these mind-blowing figures. Google's "total electricity consumption jumped from 31 terawatt hours (TWh) in 2024 to 43 TWh in 2025." In ONE year. The AI corporate arms race is eating the world.
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Ye Lab @liye-tsri.bsky.social · 02/07/2026
Our new preprint is out!! The human brain runs on ~20 watts. Computers and modern AI systems require vastly higher energy. This gap raises a fundamental question: how does the brain compute so efficiently? In our new study, we take a critical step toward measuring and understanding this directly 1/3
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Valentin Riedl @vavatin.bsky.social · 24/06/2026
Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Valentin Riedl @vavatin.bsky.social · 17/06/2026
it‘s hot again in Bordeaux 😎 and Wednesday is neuroenergetics day: find Mahnaz‘s oral presentation and Samira‘s poster dates below and drop by for discussions! #ohbm2026 @samomat.bsky.social, @mahnazAshrafi
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Ali Maximilian Erturk @erturklab.bsky.social · 13/06/2026
See our science at Deep Piction, how we use it to develop new precision medicine.
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Valentin Riedl @vavatin.bsky.social · 09/05/2026
Samira's work made the cover of @natneuro.nature.com this month 🎉 🔗 nature.com/neuro/volumes/29/issues/5 I also want to highlight two recent comments that engage with our quantitative approach to interpreting the BOLD signal; both are worth reading (see below).
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practiCal fMRI @practicalfmri.bsky.social · 09/05/2026
Multiplexed magnetic resonance imaging (MRx). www.nature.com/articles/s41... 22 measures incl. T1, T2, main metabolites in 14 min. A technical tour de force, but I'm not sure where/how it will find clinical applications.
nature.com
Multiplexed magnetic resonance imaging - Nature
A new approach to magnetic resonance imaging, ‘multiplexed magnetic resonance imaging’, is reported, which enables high-resolution simultaneous multiparametric mapping of multiple molecules in standar...
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Manlio De Domenico @manlius.bsky.social · 19/04/2026
I didn’t expect a short video about an octopus to stay with me this long. At first, it looks like a simple, almost playful interaction. But the more you watch, the more something deeper emerges: a learning process unfolding between two completely different forms of intelligence. 🧵 1/
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Agnès Landemard @agnesland.bsky.social · 15/04/2026
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
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Hugo Spiers @hugospiers.bsky.social · 14/04/2026
This looks like a significant discovery from Doris Tao's lab: Rapid concerted switching of the neural code in the inferotemporal cortex @nature.com "..our findings indicate that there is a previously unknown mechanism for neural representation:.." www.nature.com/articles/s41...
nature.com
Rapid concerted switching of the neural code in the inferotemporal cortex - Nature
Face cells in the macaque inferotemporal cortex are initially able to detect faces and then rapidly switch to a face-specific neural code to discriminate between different face identities.
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Valentin Riedl @vavatin.bsky.social · 16/12/2025
fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:
BOLD signal changes can oppose oxygen metabolism across the human cortex, Nature Neuroscience
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Nils Kroemer @nbkroemer.bsky.social · 10/12/2025
What started as a spinoff project for Madeleine's PhD became one of the most striking indications that glucose levels play an important role in regulating everyday stress responses. This shows the potential of biosensors to evaluate whether metabolism alters stress reactivity #neuroskyence 🩺
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Manlio De Domenico @manlius.bsky.social · 08/12/2025
What if complex life began when evolution hit a search bottleneck? Across 6,500+ species, 🧬 length follow a scale-invariant law. At eukaryote origins, proteins plateau while 🧬 keep growing as noncoding regulatory DNA. Phase transition? www.pnas.org/doi/10.1073/... 👉 manlius.substack.com
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Peter Bandettini @fmri-today.bsky.social · 05/12/2025
One of the more provocative and important articles I've read in a while: A call for a "map" of neuroscience understanding and relationships between domains. apertureneuro.org/article/1388...
apertureneuro.org
Bridging the epistemological divide in neuroscience to improve ontological clarity | Published in Aperture Neuro
By Giulia Baracchini, Eli Muller & 1 more. This perspective highlights the epistemological divide that arises from the wide variety of different experimental approaches... which in turn lead to ontolo...
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Shannon Macauley @macauleylab.bsky.social · 13/11/2025
Our new review is out today! 𝗧𝗵𝗲 𝗘𝗻𝗲𝗿𝗴𝗲𝘁𝗶𝗰 𝗖𝗼𝗹𝗹𝗮𝗽𝘀𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿’𝘀 𝗕𝗿𝗮𝗶𝗻: 𝗠𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝗰 𝗜𝗻𝗳𝗹𝗲𝘅𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗔𝗰𝗿𝗼𝘀𝘀 𝗖𝗲𝗹𝗹𝘀 𝗮𝗻𝗱 𝗡𝗲𝘁𝘄𝗼𝗿𝗸𝘀 We argue that Alzheimer’s disease is not just a problem of brain hypometabolism, but a disorder of metabolic inflexibility. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks
Metabolic inflexibility in Alzheimer's disease. Schematic illustrating the biphasic trajectory of metabolic activity relative to canonical Alzheimer's disease (AD) biomarkers. In the presymptomatic p...
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Richard Huskey @richardhuskey.bsky.social · 02/11/2025
🧵 What does it take to build a small, scrappy, and successful communication neuroscience lab? Our lab, @gongxuanjun.bsky.social, @rachaelkee.bsky.social, Allyson Snyder, Ziyu Zhao, and I put out heads together to answer this question. Here's what we came up with: link.springer.com/chapter/10.1...
Cover for the book "Creating Communication and Media Research Labs: A Blueprint for Success". Edited by Chad Edwards, Autumn Edwards, and Patric R. Spence. Published by Palgrave Pivot.
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Ole Jensen @olejensen.bsky.social · 11/10/2025
Ever wonder how you read so fast? Your brain gets a head start—processing the next word before your eyes move. Our MEG + eye tracking study out in Nature Communications study from @thechbh.bsky.social reveals orthographic & semantic previews predicting reading speed www.nature.com/articles/s41...
nature.com
Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading - Nature Communications
Combining MEG, eye-tracking, and representational similarity analysis, this study shows that readers rapidly and sequentially extract orthographic and semantic information from upcoming words before fixation, supporting efficient reading.
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Sofie Valk @sofievalk.bsky.social · 19/09/2025
Hello! It has been a while, but for the Hector Fellow Academy I created a small project at the interface of neuroscience and music. In short, it is like a neuro-jukebox of projects of friends and colleagues integrating music and art. I thought it would be nice to share here cng-lab.github.io/kiosk
cng-lab.github.io
NEUROSONICS
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Nature @nature.com · 22/07/2025
Nature research paper: Mitochondrial origins of the pressure to sleep go.nature.com/40oC7Y4
go.nature.com
Mitochondrial origins of the pressure to sleep - Nature
Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
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Reposted by Valentin Riedl
Edvard I Moser @edvardmoser.bsky.social · 26/06/2025
Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...
science.org
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
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layerfmri.bsky.social @layerfmri.bsky.social · 27/05/2025
At today's layer-fMRI seminar, @ofgulban.bsky.social presented stunning high resolution vein mapping tools. It left me quite excited. youtu.be/0V8fSjo2T2w?...
youtu.be
Faruk Gulban: Meso Veins Meet Layer fMRI in High-Speed Data Exploration for the New Mesoscopic Era
YouTube video by Layer fMRI
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Martin Lauritzen @mlauritz.bsky.social · 06/05/2025
Your brain functions not only as a thinking organ but also as a miniature water factory. We here calculate how much water neuronal mitochondria produce by glucose oxidation: 300-400 ml. Of that amount, 100 ml go into brain's interstitial fluid. fluidsbarrierscns.biomedcentral.com/articles/10....
fluidsbarrierscns.biomedcentral.com
A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep - Fluids and Barriers of the CNS
Maintaining brain fluid homeostasis is of critical importance for creating a stable environment conducive to optimal neuronal functioning, nutrient distribution, and waste product removal. In this stu...
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Valentin Riedl @vavatin.bsky.social · 30/04/2025
truely multiscale brain data on neuroenergetics
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Valentin Riedl @vavatin.bsky.social · 27/03/2025
The brain’s energy landscape as a potential window into brain health www.nature.com/articles/d41... (study led by Martin Picard and Michel Thiebaut de Schotten)
nature.com
First map of human brain mitochondria is ‘groundbreaking’ achievement
Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
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ISMRM @ismrm.bsky.social · 28/02/2025
Have questions about the ISMRM MiniHub in Lille, France? Get all your questions answered in an informal drop-in Zoom session with the Organizing Committee. Whether you're already registered or considering attending, stop by and ask us anything! Register now: ow.ly/8Rgx50V6Xgr #ISMRM #ISMRMMiniHub
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Jeremy Berg @jeremymberg.bsky.social · 16/02/2025
Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n
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Bratislav Misic @misicbata.bsky.social · 12/02/2025
Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1... Led by Justine Hansen Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
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The Transmitter @thetransmitter.bsky.social · 07/02/2025
Neurons primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice. By @giorgiag-sciwriter.bsky.social www.thetransmitter.org/metabolism/f...
thetransmitter.org
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
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Tobias Staudigl @tobiasstaudigl.bsky.social · 29/01/2025
📢 New preprint from the lab: We are very excited to report the discovery of an oscillation in the Central Thalamus using rare direct recordings of human thalamic electrophysiology. The novel oscillation is tightly coupled to specific, natural states of consciousness.🧵
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Phil Corlett @philcorlett.bsky.social · 16/01/2025
David Lynch was an artist in all aspects of his life. I am a particular fan of his hair. He would have played Karl Friston in an fMRI biopic. RIP
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Ida Momennejad @neuroai.bsky.social · 20/12/2024
Honored that a piece I wrote made it to NYTimes. It’s about how my mom’s stroke changed my connection to time, science, and nature. What a privilege to honor my mom in Modern Love. Below is a gift link. Let me know your thoughts 🙏🏼 www.nytimes.com/2024/12/20/s...
nytimes.com
Grief Makes Us Time Travelers (Gift Article)
A neuroscientist studying memory, I used to believe time was linear. Then my mother had a stroke.
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Bratislav Misic @misicbata.bsky.social · 19/12/2024
Mapping neuropeptide signaling in the human brain | doi.org/10.1101/2024... Neuropeptides are among the functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it brain function 🧩 🧠 ⤵️
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Danielle Beckman @daniellebeckman.bsky.social · 14/12/2024
Having a difficult day, but I'm glad to have microscopy to inspire me and hopefully inspire others as well. 💔 The brain keeps being amazing. These are neurons in the neocortex #FluorescenceFriday 🔬
Image from the microscope showing pyramidal neurons in the neocortex
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Tim Behrens @behrenstimb.bsky.social · 09/12/2024
Quick reminder that Elsevier's share price has doubled in the past 5 years: www.relx.com/investors/sh...
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Valentin Riedl @vavatin.bsky.social · 05/12/2024
beautiful and elegant 👏
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Philip Hubbard @philiphubbard.bsky.social · 03/12/2024
Here are some important populations of columnar neurons in the #Drosophila right optic lobe, from the #connectome released in April 2024 again. Note the subtle variations in morphologies. I made this video with Michael Reiser ( @michaelreiser.bsky.social), using neuVid driving #Blender.
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Zebrafish Rock! @zebrafishrock.bsky.social · 01/12/2024
Intracranial lymphatic vessels in a larval zebrafish. Credit to @zebrafish007.bsky.social. #ZebrafishZunday 🧪
Intracranial lymphatic vessels in zebrafish with Qdot angiography in magenta, lymphatics in green, Bone in blue. Learn more at Castranova et al. 2020 Circulation Research
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Tim Behrens @behrenstimb.bsky.social · 01/12/2024
OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019). The renamed: Bluesky-sized history of neuroscience (biased by my interests)
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Ali Maximilian Erturk @erturklab.bsky.social · 29/11/2024
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...
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Micah G. Allen @micahgallen.com · 25/11/2024
After a couple weeks, I've added a few hundred of you to Brain and Mind by request. The list is really an awesome source of posts in neuroscience, cognitive neuroscience, and compneuro. Has basically replaced my home feed! bsky.app/profile/did:...
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Micah G. Allen @micahgallen.com · 25/11/2024
The thing I am struggling with most as a PI is getting projects across the finish line. There are so many preprints, manuscripts, grants, tasks, and admin things to do that I feel like I am pushing the rock up the hill but never making true progress. Just picking a task each day becomes difficult.
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Danielle Beckman @daniellebeckman.bsky.social · 22/11/2024
A forest of neurons inside your head, happy #FluorescenceFriday! 🔬🧪🧠
Microscopy image of a piece of the cortex of rhesus macaque. Markers shown are dapi (blue), pyramidal neurons in yellow (smi32),  calreticulin (pink), and neun (purple).
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Natasha O'Brown @natashaobrown.bsky.social · 22/11/2024
#NewPI achievement unlocked: the first #obrownlab publication is officially accepted (🍾) about #zebrafish #glia (green) and the vasculature (magenta). Thanks to our reviewers and congrats to all of the lab members! What a great 1st paper experience. Happy #fluorescencefriday ya'll!
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Felipe del Valle Batalla @fadelvalle.bsky.social · 23/11/2024
Mitochondria in axons! #FluorescenceFriday
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Jonathan Roberts @jonroberts.bsky.social · 22/11/2024
Trying to start a "reviewer 2" starter pack but I'm still working through the extensive feedback on my first version.
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Hugo Spiers @hugospiers.bsky.social · 22/11/2024
This article with authors incl. @russpoldrack.bsky.social @summerfieldlab.bsky.social @katejj.bsky.social is still on my mind when I come to thinking about conferences 'Fly less' is an important perspective: www.cell.com/neuron/fullt...
cell.com
How Can Neuroscientists Respond to the Climate Emergency?
The world faces a climate emergency. Here, we consider the actions that can be taken by neuroscientists to tackle climate change. We encourage neuroscientists to put emissions reductions at the center...
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Sofie Valk @sofievalk.bsky.social · 22/11/2024
rdcu.be/d07ia here we should how hemispheric asymmetry in the human cortex is rooted in microstructure. 🙏 Bin Wan, @amnsbr.bsky.social @sbe.bsky.social @borismontreal.bsky.social and all others not yet in Bluesky 💜
rdcu.be
Microstructural asymmetry in the human cortex
Nature Communications - The human cortex displays an anterior-to-posterior asymmetry, identified via both post-mortem and in vivo microstructural measurements. Microstructural asymmetry is...
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CLaE @claeneuro.bsky.social · 22/11/2024
Nature Neuroscience The cell-type underpinnings of the human functional cortical connectome www.nature.com/articles/s41...
nature.com
The cell-type underpinnings of the human functional cortical connectome - Nature Neuroscience
Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through functional ...
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