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Reposted by Samira Epp (she/her)

Valentin Riedl @vavatin.bsky.social · 24/06/2026

Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...

pnas.org

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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Reposted by Samira Epp (she/her)

Nico Dosenbach @ndosenbach.bsky.social · 14/06/2026

We've known that socioeconomics (SES) matters for the 🧠. New & 🤯 is that SES drowns out all other brain associations, incl. IQ. If you train an algorithm to predict IQ from brain data, it's still way better at predicting SES. Science Mag: www.science.org/doi/10.1126/... @smarek0502.bsky.social 👀🧵👇

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Samira Epp (she/her) @samomat.bsky.social · 16/06/2026

Join me at #ohbm2026 to discuss about the reliability of multiparametric, quantitative MRI on Wed and Thurs N°2502 :)

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Reposted by Samira Epp (she/her)

Valentin Riedl @vavatin.bsky.social · 09/05/2026

Samira's work made the cover of @natneuro.nature.com this month 🎉 🔗 nature.com/neuro/volumes/29/issues/5 I also want to highlight two recent comments that engage with our quantitative approach to interpreting the BOLD signal; both are worth reading (see below).

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Reposted by Samira Epp (she/her)

Valentin Riedl @vavatin.bsky.social · 16/12/2025

4: In summary, we identified varying oxygen extraction as a novel hemodynamic response type to neuronal activity, leading to paradoxically inverse BOLD signal responses, particularly in the Default Mode Network.

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Reposted by Samira Epp (she/her)

Valentin Riedl @vavatin.bsky.social · 16/12/2025

2: We found inconsistent hemodynamic responses via blood flow (CBF) across the cortex and even within the same voxels, depending on task type and baseline oxygen extraction fraction (OEF).

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Reposted by Samira Epp (she/her)

Valentin Riedl @vavatin.bsky.social · 16/12/2025

fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:

BOLD signal changes can oppose oxygen metabolism across the human cortex, Nature Neuroscience

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