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Agnès Landemard @agnesland.bsky.social · 14h

New fUSI workshop in Paris in December 🎉 join us! Opportunities for young investigator talks and travel grants available too ✨

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Emilie Macé @mace-lab.bsky.social · 14h

Exciting times for functional ultrasound! The field is growing fast—and we need to train the next generation. We’re launching the first Paris Ultrasound Workshop, on Dec 8–9 2026. 🎓 Leading experts 🧰 Open-source tools 👩‍🔬 For new & experienced users Register by Nov 15! Link: tinyurl.com/ParisfUSI

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Agnès Landemard @agnesland.bsky.social · 14/09/2026

Really cool cells and even cooler paper!

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Enny van Beest @ennyvb.bsky.social · 04/09/2026

Textbook: tracking position during navigation is primarily the job of the hippocampus. Recent findings suggest a more complicated story. Recording >20k neurons brainwide, we indeed find spatial representations in every region! With @kenneth-harris.bsky.social and @carandinilab.net

Brainwide representations of a virtual corridor

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Anyi Liu @anyiliu.bsky.social · 29/07/2026

Pyramidal cells in the cortex send a long apical dendrite to layer 1. What is its role? What happens when it's gone? ✂️ A causal spatial role for apical dendrites in the cortex Out today with @kenneth-harris.bsky.social, @carandinilab.net and @fedrossi.bsky.social www.biorxiv.org/content/10.6...

biorxiv.org

A causal spatial role for apical dendrites in the cortex

Cortical pyramidal neurons project a long apical dendrite to layer 1 (L1), to receive synaptic inputs that are thought to provide contextual and possibly suppressive modulation. In visual cortex, thes...

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Simons Foundation @simonsfoundation.org · 07/07/2026

For years, neuroscientists have sought to reconcile conflicting findings about how brain activity relates to blood flow. A new study from the Simons Collaboration on the Global Brain suggests the answer lies in a hidden balance between two opposing groups of neurons: bit.ly/3QX90to

bit.ly

Deciphering the Link Between Neural Activity and Blood Flow in the Brain

For years, neuroscientists have sought to reconcile conflicting findings about how brain activity relates to blood flow. A new study suggests that the answer lies in a hidden balance between two oppos...

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Agnès Landemard @agnesland.bsky.social · 12/06/2026

Looking forward to opening #FENS2026 with a fUSI-centric technical symposium on Monday 6 July (additional registration required!) 🤩 A great line-up to discuss opportunities and challenges in using functional ultrasound imaging for the study of internal states (and in general!). Come see us!

Technical Workshop W05 - Monday July 6, 11:00 AM - 2:00 PM
Imaging brain-wide activity across behavioral states and species using functional ultrasound imaging

Antoine Bergel (chair)CNRS Tenured ResearcherParis Brain Institute, France
Emilie MacéProfessorUniversity Medical Center, Goettingen, Germany
Agnès LandemardSenior Research FellowUniversity College London, United Kingdom
Yves Boubenec Associate ProfessorEcole Normale Supérieure, Paris, France
Thomas OrsetPostdoctoral AssociateWestern University, Canada
Sadaf Soloukey Assistant Professor, Neurosurgeon in trainingErasmus MC, Rotterdam, The Netherlands

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Matteo Carandini @carandinilab.net · 10/06/2026

Losing one side of Superior Colliculus is bad, but losing both sides seems fine. Wait, what? Flora & team discovered why: both sides press for contra actions and against inaction, obeying an incredibly simple additive rule. Out today in bioRxiv: www.biorxiv.org/cgi/content/...

A diagram showing a sequence of linear operations, with visual signals from visual cortex added to auditory signals from auditory cortex. Prefrontal cortex sums these signals and superior colliculus provides a constant, stimulus-independent factor pushing for each eligible action. The final decision is taken via softmax.

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The Transmitter @thetransmitter.bsky.social · 15/04/2026

When it comes to blood flow in the brain, not all neurons are created equal. Rather, only a subset of neurons may be driving vascular changes, a new study finds. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/neurovascula...

thetransmitter.org

Arousal neuron activity explains brain blood flow in mice

The findings could impact how researchers interpret signals from techniques that use blood flow as a surrogate for neural activity.

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Agnès Landemard @agnesland.bsky.social · 15/04/2026

How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social

The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.

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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 10/04/2026

New paper out 🎉 Awake fUSI is powerful, but motion can strongly bias the data, even in head-fixed experiments. In this paper, we tried to systematically characterize those artifacts, benchmark denoising strategies, and turn that into practical recommendations for awake fUSI of mouse brains. 1/12

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Enny van Beest @ennyvb.bsky.social · 10/11/2025

All talks of the 2025 UCL #Neuropixels course are now available: www.youtube.com/playlist?lis... For more information on the course see the website: www.ucl.ac.uk/neuropixels/... And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋. Happy Neuropixeling!

youtube.com

2025 UCL Neuropixels Course - YouTube

Lectures at the 2025 UCL Neuropixels course (https://www.ucl.ac.uk/neuropixels/training/2025-neuropixels-course)

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Agnès Landemard @agnesland.bsky.social · 24/09/2025

Happy to see my last PhD paper (finally!) out 🥳 Cross-species ferret vs. human, fUSI vs fMRI, round 2! Is the human cortical hierarchical gradient in background invariance also found in ferrets? Yes! Are they supported by the same mechanisms? No! Find out more: 👉 elifesciences.org/articles/106...

elifesciences.org

Hierarchical encoding of natural sound mixtures in ferret auditory cortex

To parse foreground and background sounds, the auditory cortex of humans and ferrets share a similar hierarchical organization, but the underlying computational mechanisms are fundamentally different.

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Enny van Beest @ennyvb.bsky.social · 16/09/2025

Join the 2025 UCL Neuropixels course (free and online!), 22-24th of October: Day 1 and 2: Get started with the basics and the latest updates on hardware & software. Day 3: Focus on how to analyse the many neurons you recorded. More info and to register: www.ucl.ac.uk/neuropixels/...

ucl.ac.uk

2025 Neuropixels course

A free online course on Neuropixels, 22-24 October 2025

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Emilie Macé @mace-lab.bsky.social · 11/09/2025

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

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International Brain Laboratory @intlbrainlab.bsky.social · 03/09/2025

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

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Alessandro Gozzi @gozziale.bsky.social · 03/09/2025

This looks pretty cool: ultrasound can now see through the skull! 🧠🔊 The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯) Huge congrats to the authors!!! www.biorxiv.org/content/10.1...

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Matteo Carandini @carandinilab.net · 24/07/2025

Introducing our new favorite stimulus. A few minutes are enough to map the visual preferences of thousands of neurons. Mapping the visual cortex with Zebra noise and wavelets www.biorxiv.org/content/10.1... By Sophie Skriabine and Max Shinn, with Samuel Picard and @kenneth-harris.bsky.social

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Matteo Carandini @carandinilab.net · 18/07/2025

A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...

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Matteo Carandini @carandinilab.net · 07/07/2025

New by Agnès Landemard (@agnesland.bsky.social‬) & co Brainwide blood volume reflects opposing neural populations Brainwide fluctuations in blood volume arise from two populations with opposite relation to brain state and distinct relationships to blood supply www.biorxiv.org/content/10.1...

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