iiinova — where your digital self keeps evolving

Tim Craggs @timcraggs.bsky.social · 18/03/2026

Something is happening at @ei-science.bsky.social HQ… Can’t wait to show you all! But I’m going to have to - won’t be long now.

Filming equipment in the lab at Exciting Instruments HQ. Lots of cool kit everywhere.

020

Tim Craggs @timcraggs.bsky.social · 18/03/2026

Great session with the Masters students today @unisheffieldlib.bsky.social getting them all set up on @linkedin.com and more importantly here on @bsky.app Please do give them a follow when you see them posting on here - part of their ‘homework’ this week ;) Just posting on my way out…

Selfie of me on my way to the car - wearing my Exciting Instruments stash

020

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 24/02/2026

👀 At #BPS but haven’t stopped by booth 401 yet? Meet the team to discover how you can unlock the ultimate #single-molecule resolution at your benchtop, generating high-impact insights into #biomolecular interactions and dynamics. See you there! @biophysicalsoc.bsky.social #biophysics #lifescience

064

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 17/02/2026

🚀 Big news from @timcraggs.bsky.social x #BPS2026: meet the new EI-FLEX Pro! Automated alignment + focus, real-time analysis with publication-ready plots, modular upgrade to 96/384 wells, no darkroom or optical table, compact benchtop. Meet us at booth 401 or get in touch for a demo! #singlemolecule

0196

Reposted by Tim Craggs

Prof. Zoë Waller @drzoewaller.bsky.social · 03/02/2026

New paper out! i-Motif, not G-quadruplex, stability regulates insulin expression - published in @narjournal.bsky.social Team effort driven by Dr Dilek Guneri supported by Dr Chris Morris, @timcraggs.bsky.social, @yiliangding.bsky.social and Prof Steve Smith academic.oup.com/nar/article/...

academic.oup.com

Validate User

1115

Reposted by Tim Craggs

Steve Quinn @steve-quinn-lab.bsky.social · 22/01/2026

Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬 @timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social 👇 tinyurl.com/bdznxur3

01910

Reposted by Tim Craggs

Quentin Smith @qmsmith.bsky.social · 22/01/2026

🗣️ Keynote Speaker: @sulianamanley.bsky.social 👥 Mentoring Session: Careers Across Biophysics featuring @valdavinson.bsky.social @timcraggs.bsky.social @sulianamanley.bsky.social @esisamakis.bsky.social 📈 Selected talk and poster presenters: You! ☀️ Please repost, share and we'll see you in June!

053

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 11/11/2025

Join Kuang and @timcraggs.bsky.social on 20th November to discuss his findings in more detail as part of our next Exciting Seminar - 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... 🧵 4/4 #structuralbiology #biophysics

022

Reposted by Tim Craggs

Barbara Ciani @drbciani.bsky.social · 08/11/2025

Can't decide if you like Biochemistry, Chemistry or Biophysics? Do all three! The bonus? You get to learn advanced biophysics with Prof Sarah Harris and @timcraggs.bsky.social and be exposed to the dynamic environment of @ei-science.bsky.social Application information: lnkd.in/eW9VxNBW

lnkd.in

This link will take you to a page that’s not on LinkedIn

022

Tim Craggs @timcraggs.bsky.social · 07/11/2025

Opening the London Stock Exchange - that’s all…

091

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 07/11/2025

📢 Our Exciting Seminars are back! Join @timcraggs.bsky.social & @shenk0128.bsky.social on Nov 20 for 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... #biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret

011

Tim Craggs @timcraggs.bsky.social · 03/11/2025

Love the optics here - see the reflection! We are welcoming a lot of people to @ei-science.bsky.social getting great data on their own biological systems for prelim data for grants. It’s nice to have a greta space to welcome them to! Is there an #smFRET experiment you’d like to try? Ping me here!

The entrance lobby for the new Exciting Instruments facility - with cool 3D logos and reflections in the window an interesting way around!

080

Reposted by Tim Craggs

Steve Quinn @steve-quinn-lab.bsky.social · 31/10/2025

🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk ! Find out more & apply by 4th Dec: tinyurl.com/yt36p9tx @ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social

144

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 02/10/2025

🚀 Since spinning out in 2021, our journey has been an Exciting one! Thrilled to see our CEO & founder @timcraggs.bsky.social named Entrepreneur of the Month by Insider Magazine. Read Tim’s comment below and the article here 👉 flickread.com/edition/html... #entrepreneur #singlemolecule #sheffield

081

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 11/09/2025

Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email info@excitinginstruments.com to schedule! #biophysics #smfret #fcs

001

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 10/09/2025

What is single-molecule FRET? Watch @timcraggs.bsky.social explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET

youtu.be

What is single-molecule FRET?

YouTube video by Exciting Instruments

052

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 18/08/2025

🙌 Excited to share that our CEO @timcraggs.bsky.social has been elected to @biophysicalsoc.bsky.social alongside Robert Best, Tanja Mittag & Kandice Levental. Congrats also to Enrique M. De La Cruz, elected President-elect! #biophysics #lifescience #biophysicalsociety

083

Tim Craggs @timcraggs.bsky.social · 12/08/2025

Holiday time! So good to recharge with family…

140

Reposted by Tim Craggs

Izzy Jayasinghe @ijayas.bsky.social · 30/07/2025

🚨Job Alert: My department in UNSW Sydney is recruiting a teaching-only Lecturer in Biophysics. The lecturer will play a key role in the pedagogical development and delivery of courses and practicals in the new undergraduate (BSc) major in #Biophysics that we are launching from 2026. #AcademicBsky 🧪

external-careers.jobs.unsw.edu.au

Lecturer in Biophysics, Education Focused

The incumbent will contribute to undergraduate teaching in Biophysics and across related disciplines within the School of Biomedical Sciences. Some responsibilities include preparing and delivering le...

02621

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 28/07/2025

🤔 What if we could detect disease from a single molecule before symptoms even appear? This isn’t just innovation. It’s a shift in how we understand, detect, and prevent illness. Molecular insights are unlocking a new era in human health. #innovation #lifescience #biophysics

022

Tim Craggs @timcraggs.bsky.social · 27/07/2025

Come on England! 🏴󠁧󠁢󠁥󠁮󠁧󠁿

110

Tim Craggs @timcraggs.bsky.social · 22/07/2025

Come on England!! Always make is wait - but what a result!

000

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 22/07/2025

Are you a @biophysicalsoc.bsky.social member? Vote in the 2025 election by 01/08! @timcraggs.bsky.social is nominated as Industry Rep. We encourage everyone to vote for this important cause, regardless of who you're voting for 🙂 www.biophysics.org/elections/bp... #biophysics #lifescience

054

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 04/07/2025

Voting in the KPMG Private Enterprise Tech Innovator in the UK competition is open! Show Exciting Instruments - and Yorkshire and the North East - your support by voting below 👇 app.sli.do/event/dkwYDn... #innovation #startups #deeptech #yorkshire #sheffield

022

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 23/06/2025

Forget what you think you know about single-molecule fluorescence spectrometry instruments! Introducing the EI-FLEX... Find out more and request a tech spec > bit.ly/45AqRLv #singlemolecules #biophysics #smfret #fcs #innovation

022

Reposted by Tim Craggs

Greg Egan @gregegansf.bsky.social · 22/06/2025

The antihero in my story “Crisis Actors” uses cylindrical mirror anamorphism as an “encryption” technique [he’s not very bright], but I’d never seen it done with 3D objects rather than just flat images until I stumbled on this article about the sculptor Jonty Hurwitz.

1668

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 18/06/2025

🇮🇹 The countdown to #EBSA2025 is on! @timcraggs.bsky.social, Paul Wheeler and @dr-mahmoud.bsky.social will be on hand to discuss all things single molecule! Book a catch up here > meetings-eu1.hubspot.com/pwheeler/ebs... #EBSA #biophysics #singlemolecule

021

Tim Craggs @timcraggs.bsky.social · 18/06/2025

Swag day! Loving the new branding @ei-science.bsky.social Great work @jessicaei.bsky.social And not on here Dr Paul Wheeler!

160

Reposted by Tim Craggs

Siân Owen @sianowen.bsky.social · 03/06/2025

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

34961

Reposted by Tim Craggs

Emmanuel Margeat @emmanuelmargeat.bsky.social · 26/05/2025

Applications are now open for the 4th edition of the “Ecole de Physique des Houches” on Fluorescence Markers for Advanced Microscopies, a WE-Heraeus seminar. March 15th-20th 2026 Join us to learn everything you wanted to know about Fluorescent Markers for advanced microscopies.

12822

Tim Craggs @timcraggs.bsky.social · 19/05/2025

Half way to 90! Here’s to the next 45 years! Awesome time celebrating with my family - carting then steak.

390

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 06/05/2025

In 2016, @timcraggs.bsky.social had a problem: He needed an instrument he couldn’t afford. So, he built one! His mission: → To democratise the smFRET method and make it accessible to as many labs as possible. In 2025, Exciting Instrument is speeding up (exciting announcements coming up!) 🚀

052

Reposted by Tim Craggs

Ursula von der Leyen @vonderleyen.ec.europa.eu · 05/05/2025

Europe’s choice is clear. To put science at the heart of its economy. To become the home of scientific freedom and collaboration. And to welcome talent from all over the world. I’m glad to present the first elements of our Choose Europe Initiative. → europa.eu/!TTbWbJ

1204021963

Tim Craggs @timcraggs.bsky.social · 03/05/2025

Ok people - I’ve not been to the cinema in a while - but was stunned at the price for this little lot… any guesses?

3 regular popcorn - 2 ice blast - 1 coke

120

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 17/04/2025

Are you in the mood for: - Nice single-molecule data - Technical discussions on smFRET - What’s coming next to better support the users? You can get it in a webinar replay hosted by @timcraggs.bsky.social Guests: Hermia Kung, @steve-quinn-lab.bsky.social Link: www.youtube.com/watch?v=9eq-...

021

Reposted by Tim Craggs

Nonia Pariente @npariente.bsky.social · 25/03/2025

When they go low, you go high, said a very wise woman Just goes to show how pathetic Europe is exactly 💪🏻🧪 (Well done European Commission and ERC)

03711

Tim Craggs @timcraggs.bsky.social · 25/03/2025

I’m the fastest! Actually - that’s not entirely true. Mahmoud will get your smFRET experiment up and running in a matter of seconds - with data analysed in real time and streamed to your phone / laptop in minutes. Come chat at Booth 18 #POL2025 Physics of Life = Biophysics = Molecular Biology

060

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 21/03/2025

The most exciting biophysics meetup this month is happening in the UK! Physics of Life | Harrogate | 24 -27 March Exciting Instruments will be there! If you like talking single-molecule biophysics: Don’t forget to pass by booth 18 to meet @timcraggs.bsky.social and @dr-mahmoud.bsky.social

031

Reposted by Tim Craggs

Canadian History Ehx @cdnhistoryehx.bsky.social · 20/03/2025

On this day in 1879, Maud Menten was born in Port Lambton, Ontario. In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field. Let's learn more about her life! 🧵1/10

A black-and-white photo shows a woman in a patterned dress with a lace collar and pearl necklace, sitting in a chair. The background features shelves with bottles and a wire basket, suggesting an early 20th-century setting, possibly a pharmacy or study.

3266113

Tim Craggs @timcraggs.bsky.social · 11/03/2025

Don’t miss out! Come for @steve-quinn-lab.bsky.social Stay for awesome data from undergraduate summer student Hermia King. Leave before Tim gets too excited and you all end up buying a benchtop instrument for smFRET and FCS ;)

050

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 10/03/2025

🔔 Happening TOMORROW: → 3 scientists → 2 case studies → 1 roundtable discussion with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social Join us live When: 11th March 2025 | 5 PM GMT (12 PM ET) Why: To talk about single-molecule studies using smFRET. Where: buff.ly/J5P2J8s

032

Tim Craggs @timcraggs.bsky.social · 09/03/2025

We have got to do better than this…

000

Reposted by Tim Craggs

Adriana Guatame-García @adriguatame.bsky.social · 06/03/2025

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩‍🔬

There have been people less than helpful in my journey here. I wanted to acknowledge those too, bc I know I am not unique in this experience.
No thank you to the physics study assoc that made me sing songs about how women couldn't study physics without sleeping with the professor, the day I stepped into university life. No thank you to the 5th year physics student that decided to assign me a stripper name within the first minute of meeting me in the physics coffee corner in my first year. No thank you to the technician that was responsible for onboarding me on the use of the cluster in my third year who raised his eyebrows and asked me if that meant I was some sort of computer girl. No thank you to the senior researcher that sent me utterly inappropriate texts after a conference, then proceeded to apologise months later by telling me they had not been meant for me anyway so no hard feelings remain hopefully And no thank you to him for attending every conference I've been to since. No thank you to the people who told me that it was surprising that I was doing a PhD since I was a girl. No thank you to the man who mistook me for a coffee lady at a conference, and after having to correct him two times that I did not work there, responded with you should consider it. No thank you to the researcher that asked me what I was wearing underneath my outfit during a conference. No thank you to the physicist who declared to a room full of other physicists that biologists don't know how to design an experiment. No thank you to the people who have called me scary instead of strong and intimidating instead of intelligent.
And finally, no thank you to the exec board of the TU Delft, whose knee-jerk reaction to being held up a mirror about the social safety at the university, was to sue the party holding up the mirror instead of looking at the problems they highlighted.
... You have made me feel like I do not belong in science & I cannot forgive you for that.

12365132320

Reposted by Tim Craggs

Exciting Instruments @ei-science.bsky.social · 04/03/2025

🚨 Exciting Seminar coming up! → Unravelling the FLEXibility of DNA hairpins and novel RNA systems with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social ⏰ 11th March 2025 | 5 PM BST (12 PM ET) 🔥 Bonus: A roundtable discussion! Register here: buff.ly/J5P2J8s

053

Tim Craggs @timcraggs.bsky.social · 04/03/2025

Awesome PhD opportunity in a great collaborative team - and maybe even some single-molecule FRET!!

010