Cancer cell plasticity underlies tumor progression, metastasis and therapeutic resistance, yet how RNA-binding proteins regulate malignant state transitions remains poorly defined. Here, we identify t...

Summary: This Special Article provides a comprehensive overview of the methods, applications and considerations for the generation of cerebellar organoids.

Yuan et al. present S2-omics, an end-to-end workflow that automatically identifies regions of interest in histology images to maximize molecular information capture in spatial omics experiments.

In this perspective, Zagozewski et al. summarize current knowledge about the primitive neurodevelopmental programs that drive medulloblastoma progression. The authors also highlight the unmet needs in...

It is currently understood that the characteristic loss of the repressive histone mark H3K27me3 in PFA ependymoma and diffuse midline glioma (DMG) are caused by complementary mechanisms mediated by EZ...

Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry involved in the production of complex behaviors

The Developmental, Stem Cell & Cancer Biology program has led significant discoveries in developmental genetics, genomics, stem cell and cancer biology.

In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms ...

Job title: Locum Associate or Senior Editor, Nature (Biological, Clinical, and Social Sciences) Location: New York or Berlin (Hybrid working pattern) Deadline: June 11th , 2025 About Springer Nature G...

The cerebellar ventricular zone (VZ) is the primary source of progenitors that generate cerebellar GABAergic neurons, including Purkinje cells (PCs...

As US federal grants remain frozen and budget cuts loom, anxiety and fear grip early-career researchers.

Title: Associate or Senior Editor, Nature Communications (Stem Cell and Developmental Biology) Location(s): New York, Jersey City, Philadelphia, Berlin or Heidelberg Application Deadline: About Spring...

RNA translation is a core cell process that is deregulated in cancer. Here, the authors show that a machine learning approach, RiboTIE, can reconstruct RNA translation in cancer and non-cancer cells. ...

Job Title: Deputy Editor - Communications Biology Locations: New York or Berlin - Hybrid Working Model Application Deadline: February 17th About Springer Nature Group Springer Nature opens the doors t...

Promoting and advancing molecular understanding of biology

Analysis of medulloblastomas in humans and mice shows that the functional consequences of ZIC1 mutations are exquisitely dependent on the cells of origin that give rise to different subgroups of medul...

Werbowetski-Ogilvie, Taylor and colleagues report a noncanonical role for OTX2 in regulating alternative splicing and controlling a stem cell and pro-tumorigenic splicing program in group 3 medullobla...