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Lena Kutscher

@lenakutscher.bsky.social
483 followers 346 following 81 posts

Scientist at dkfz, Twin mom + 1. Developmental Origins of Pediatric Cancer junior group leader. Interested in cerebellum development, tumor initiation, and cell death 🧪

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Reposted by Lena Kutscher
Kacy Gordon @kacylynn.bsky.social · 28/09/2026
JOB ALERT: UNC Bio is hiring 2 tenure track assistant profs doing molecular, cell, and dev bio. The search is intentionally broad, so please share widely and spread the word! Find more information and apply here: unc.peopleadmin.com/postings/325... Application review begins Nov 1.
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Reposted by Lena Kutscher
Max-Planck-Gesellschaft @maxplanck.de · 09/09/2026
We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack
Call for independent Max Planck Research Groups
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Lena Kutscher @lenakutscher.bsky.social · 03/09/2026
Excited to be awarded an ERC STG to continue our work on sex differences in medulloblastoma. Also happy that the ERC was also awarded to two other great people at DKFZ and my grad school roommate Kimberly Siletti at the UMCU!
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Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 03/09/2026
Three DKFZ-researchers have each been awarded a Starting Grant from the @erc.europa.eu this year. Daniel Kirschenbaum, Lena Kutscher and Michael Scherer impressed the ERC with their innovative research approaches to fundamental questions in cancer medicine. Congratulations! 👏 #ERCStG t1p.de/tk12d
t1p.de
Triple ERC Success at the German Cancer Research Center
Three researchers at the German Cancer Research Center (DKFZ) have each been awarded a Starting Grant from the European Research Council (ERC) this year. Daniel Kirschenbaum, Lena Kutscher, and Michael Scherer impressed the ERC with their innovative research approaches to fundamental questions in cancer medicine. With the funding, they plan to investigate why certain brain tumors occur more frequently in boys than in girls, how brain tumors suppress the immune system, and which epigenetic characteristics make cancer cells resistant to drugs.
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The Company of Biologists @biologists.bsky.social · 26/08/2026
Deadline is 31 August to register for the Innovative Preclinical Models for Pediatric Cancer Research meeting, hosted by @dmmjournal.bsky.social. Hear talks from an outstanding line up of speakers and apply to present a poster. www.biologists.com/meetings/dmm...
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Lena Kutscher @lenakutscher.bsky.social · 05/08/2026
We're recruiting a postdoc to study the molecular and cellular basis of the male bias in medulloblastoma! Please apply through the DKFZ Postdoc Program until September 8th. Our project is under B430_Developmental Origins. Please get in touch with questions! jobs.dkfz.de/en/jobs/1687...
jobs.dkfz.de
DKFZ Postdoctoral Fellowships 2026
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Reposted by Lena Kutscher
Michael Raissig @michaelraissig.bsky.social · 07/08/2026
🌾 We're hiring a postdoc! Join the Stomatal Biology group in beautiful Bern @unibe.ch How do grass leaves spatially coordinate development of veins & stomatal rows? 2 years (plus possible extension), funded by @snsf.ch @dfg.de within @cerealcell.bsky.social RU5325 jobs.unibe.ch/job-vacancie...
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Dr. Becca @docbecca.bsky.social · 06/08/2026
Please share--the Shansky lab is currently recruiting at all levels to work on an NIH-funded project investigating sex differences in the neural circuits that drive defensive behaviors. The official job ad isn't yet up, but interested folks can contact me as instructed here www.shanskylab.com/join
shanskylab.com
Join — Shansky Lab
The lab at our end-of-semester field day
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Lena Kutscher @lenakutscher.bsky.social · 05/08/2026
We're recruiting a postdoc to study the molecular and cellular basis of the male bias in medulloblastoma! Please apply through the DKFZ Postdoc Program until September 8th. Our project is under B430_Developmental Origins. Please get in touch with questions! jobs.dkfz.de/en/jobs/1687...
jobs.dkfz.de
DKFZ Postdoctoral Fellowships 2026
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Reposted by Lena Kutscher
Vuslat Akçay @vuslatakcay.bsky.social · 01/08/2026
Our work is now online! I'm excited to be presenting this project starting today at #GRS, followed by #GRC on Neural Development in Newport, Rhode Island. If you're attending, I'd love to connect. Please come find me! #GordonResearchConferences #NeuralDevelopment
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Lena Kutscher @lenakutscher.bsky.social · 01/08/2026
New preprint from the lab! Led by PhD students @vuslatakcay.bsky.social, Lisa Spänig and Wouter-Michiel Vierdag (EMBL), we investigated the development and differentiation of cerebellar unipolar brush cell progenitors (UBCPs). www.biorxiv.org/content/10.6...
biorxiv.org
Conserved cerebellar rhombic lip compartmentalization and Eomes regulatory networks govern unipolar brush cell development
The rhombic lip (RL) gives rise to all cerebellar glutamatergic cell types, including unipolar brush cells (UBCs). Disruptions to UBC development can lead to the neurodevelopmental disorder Dandy-Walk...
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Marieke Oudelaar @mariekeoudelaar.bsky.social · 07/07/2026
We are looking for someone to lead the new Facility for Protein Biochemistry & Biophysics at the MPI of Immunobiology and Epigenetics in Freiburg — please spread the word and apply if you are interested!
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Eric Chevet @ericchevet.bsky.social · 18/06/2026
The elephant in the room: impact factor journals.biologists.com/dev/article/...
journals.biologists.com
The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
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Reposted by Lena Kutscher
DMM Journal @dmmjournal.bsky.social · 01/06/2026
Lena Kutscher @lenakutscher.bsky.social is speaking on '2D and 3D models of embryonal brain tumor initiation' at our Journal Meeting this October #DMM2026cancer #pediatriccancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026
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Reposted by Lena Kutscher
Maryam Zaringhalam @webmz.bsky.social · 01/06/2026
There's been a lot of chatter about proposed updates to the Office of Management and Budget (OMB) Federal Financial Assistance Rule, which is, to put it bluntly: destructive to the integrity of federally supported research. 🧵 thread...
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Lena Kutscher @lenakutscher.bsky.social · 21/05/2026
This October, I'll present our work on new iPSC-derived stem cell models @dmmjournal.bsky.social’s meeting on Innovative Preclinical Models for Pediatric Cancer Research. It looks like a great meeting, so please join us for some exciting science and fun discussions!! bit.ly/46r84Ca #DMM2026cancer
bit.ly
DMM26: Innovative Preclinical Models for Pediatric Cancer Research
Innovative Preclinical Models for Pediatric Cancer Research Cancer in children represents ∼3% of the global incidence of cancer. Pediatric cancer exerts an outsized impact: beyond the physical and emo...
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Reposted by Lena Kutscher
The Company of Biologists @biologists.bsky.social · 23/04/2026
Join researchers working on pediatric cancer at @dmmjournal.bsky.social's meeting in October at Nationwide Children’s Hospital, USA. Organisers: James Amatruda @amatrudalab.bsky.social, Pratiti (Mimi) Bandopadhayay @bandolab.bsky.social , Ana Banito & Elaine Mardis Register at tinyurl.com/bddksc4v
Speaker list and science image
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Mari Sepp @marisepp.bsky.social · 20/04/2026
By applying for an MSCA Postdoctoral Fellowship with the University of Tartu, you can access 3 funding pathways: MSCA, ERA Fellowships, and national funding schemes. Get in touch if interested in brain development, autism spectrum disorders, and single-cell genomics. ut.ee/en/content/p...
ut.ee
Postdoctoral research at the University of Tartu
Estonia, a hub of innovation and cutting-edge research, offers a vibrant ecosystem for postdoctoral researchers.
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Reposted by Lena Kutscher
Mark Hartmann @mphartmann.bsky.social · 02/04/2026
Excited to present our work at the 2026 #ISEH Mini Symposium! “Beyond the Maturation Block: Oncofetal Reprogramming and Stem Cell Plasticity in Pediatric Leukemia” Join us on April 16 to discuss developmental programs in leukemia and beyond. iseh.org/Webinars-Eve...
iseh.org
Mini Symposium
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Mari Sepp @marisepp.bsky.social · 31/03/2026
Exciting study by @lenakutscher.bsky.social and @doctorpauln77.bsky.social on male bias in medulloblastoma: “testosterone and the XY genotype cooperate to increase the abundance of specific cerebellar progenitor populations” Elegant use of Four Core Genotypes mice + recapitulation in organoids
ky.social
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Lena Kutscher @lenakutscher.bsky.social · 30/03/2026
Here's the preprint!!
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Lena Kutscher @lenakutscher.bsky.social · 30/03/2026
New preprint alert! I'm excited to share our latest preprint where we investigate the underlying developmental causes of the male bias in the pediatric brain tumor Group 3/4 medulloblastoma. www.biorxiv.org/content/10.6...
graphical abstract for "Developmental determinants of male bias in medulloblastoma" preprint. We propose that boys are more likely to develop Group 3/4 medulloblastoma more vulnerable cells-of-origin are available for transformation. Specifically, GC_UBC progenitors in the developing cerebellum are more abundant in male murine embryos, as a result of testosterone exposure and the XY genotype.
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Lena Kutscher @lenakutscher.bsky.social · 24/03/2026
Go Roy!!!
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Reposted by Lena Kutscher
Lena Kutscher @lenakutscher.bsky.social · 18/03/2026
We’re looking for a HiWi to join our team! In case you know any current BSc or MSc students, preferably in an early semester, please send them our way. No need for prior experience - we’ll teach the necessary skills! jobs.dkfz.de/en/jobs/1684...
jobs.dkfz.de
Student / Scientific Assistant for 39 hours/month
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Lena Kutscher @lenakutscher.bsky.social · 24/03/2026
interested in working on sex differences during development and in tumor initiation! come join our lab via the MSCA MasterClass
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Lena Kutscher @lenakutscher.bsky.social · 18/03/2026
We’re looking for a HiWi to join our team! In case you know any current BSc or MSc students, preferably in an early semester, please send them our way. No need for prior experience - we’ll teach the necessary skills! jobs.dkfz.de/en/jobs/1684...
jobs.dkfz.de
Student / Scientific Assistant for 39 hours/month
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Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 12/03/2026
The next #ScienceatDKFZ event will take place on Thursday, 19 March 2026, at 4 pm. In addition to the keynote lecture by Sigrid Carlsson, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications. 👉 dkfz.de/en/news/even...
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DMM Journal @dmmjournal.bsky.social · 02/03/2026
Registration is open for @dmmjournal.bsky.social 2026 meeting 'Innovative Preclinical Models for Pediatric Cancer Research' organised by James Amatruda amatrudalab.bsky.social, Pratiti (Mimi) Bandopadhayay, bandolab.bsky.social, Ana Banito & Elaine Mardis. Find out more bit.ly/46r84Ca #DMM2026cancer
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Lena Kutscher @lenakutscher.bsky.social · 27/02/2026
They figured out meander tail mouse has an Mysm1 mutation! I have been curious about this mouse since I got into the cerebellum field, as this mouse is the only model identified so far that has defects preferentially in the anterior cerebellum. very cool follow up!! www.biorxiv.org/content/10.6...
biorxiv.org
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Lena Kutscher @lenakutscher.bsky.social · 11/02/2026
Ramsey Najm and I have a joint postdoc position advertised through the @hlsalliance.bsky.social Interinstitutional Postdoc call! Our project proposes to generate better posterior cerebellar organoids to improve fidelity of pediatric medulloblastoma models. www.health-life-sciences.de/opportunitie...
health-life-sciences.de
HEALTH + LIFE SCIENCE ALLIANCE | Interinstitutional Postdocs
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DMM Journal @dmmjournal.bsky.social · 10/02/2026
Esther Becker, Simone Mayer and @lenakutscher.bsky.social teamed up to summarise current approaches for generating #cerebellar #organoids and advocate for the establishment of rigorous quality control standards to ensure reproducible, high-quality research. Read doi.org/10.1242/dmm....
The figure shows the key features of human cerebellar patterning and gene expression. Panel A: The midbrain –hindbrain  boundary is set at ∼4-5 post-conception weeks. The isthmic organizer secretes the morphogens  to set the boundary. Panel B: around 10 weeks post conception, two progenitor pools are specified, including the ventricular zone, which generates all inhibitory neurons and glial cells, and the rhombic lip, which generates all excitatory neurons. The external granule layer is a second germinal zone producing the abundant excitatory granule neurons of the cerebellum. Panel C: at later stages in development, the cerebellum becomes highly foliated and adopts its characteristic three-layer structure. Panel D: major cell types of the mature cerebellum include Purkinje cells, granule cells, unipolar brush cells, GABAergic interneurons and cerebellar nuclei.
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Lena Kutscher @lenakutscher.bsky.social · 10/02/2026
Excited to share our preprint on our new multi-omic atlas of human hindbrain development. Led by postdoc Piyush Joshi, in collaboration with @kaessmannlab.bsky.social and Pfister labs, our atlas represents the first comprehensive view of human hindbrain development. www.biorxiv.org/content/10.6...
Brain with puzzle overlay to show that our study provides missing pieces of the puzzle of human brain development by delivering the most comprehensive picture of hindbrain development to date. We have strived to go beyond just another multi-omics atlas to gain deep insights by:
1. Meticulously annotating cell clusters
2. Extracting regulatory programs in terms of coordinated gene sets and accessible regulatory elements
3. Using deep learning to identify regulatory syntax
4. Resolving context-specific TF activity
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Lena Kutscher @lenakutscher.bsky.social · 08/02/2026
Some friends and I wrote a review with @biologists.bsky.social !! Together with Esther Becker and Simone Mayer, we explore the state of the cerebellum organoid field and offer practical guidance on getting this model system started in your own lab. journals.biologists.com/dmm/article/...
journals.biologists.com
Generating cerebellar organoids from pluripotent stem cells
Summary: This Special Article provides a comprehensive overview of the methods, applications and considerations for the generation of cerebellar organoids.
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Sam Wang @samwang.bsky.social · 07/02/2026
From my work on gerrymandering, I know that New Jersey politicians play dirty. Now my campaign faces its first test. To beat their petty games, I need at least 1,000 signatures from Democrats and unaffiliated voters in the 12th District. It's cold work. To help, sign up at SamForNJ.org - or DM me!
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Sam Wang @samwang.bsky.social · 04/02/2026
News from central Jersey: I'm running to represent New Jersey's 12th Congressional District. By entering the fray, I hope to bring ideas of repairing our frayed republic. Not only to defend it in 2026, but to build something stronger, for generations to come! samwang.substack.com/p/entering-t...
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Mari Sepp @marisepp.bsky.social · 29/01/2026
I've started my own lab 🎉 PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders. We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.
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Harmit Singh Malik @harmitmalik.bsky.social · 01/01/2026
Today I made a small but momentous start to work in 2026 by changing a single number. I renamed the file “Papers to write and submit in 2025” to “Papers to write and submit in 2026”. Stay tuned for more file updates on 1st January 2027.
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tugboatcity.bsky.social @tugboatcity.bsky.social · 23/12/2025
I love this live version of the new @themountaingoats.bsky.social song. 🎶"There's always a clock ticking somewhere."🎶 youtu.be/pv53gRqjvxY?...
youtu.be
"Cold at Night" - The Mountain Goats ft. Tommy Stinson (LIVE on The Late Show)
YouTube video by The Late Show with Stephen Colbert
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Chris Jackson @chriscjackson.bsky.social · 15/12/2025
This entire weekend
in the pit
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Christophe 🔬 Leterrier @christlet.bsky.social · 02/12/2025
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Moritz Mall @moritzmall.bsky.social · 02/12/2025
The @dkfz.bsky.social PhD Program is open, and the Mall Lab is recruiting PhD students. 1: in vivo and organoid models to study and treat autism associated disorders. 2: cancer cell plasticity in brain tumors using single cell genomics and perturbation screens. Apply now: www.dkfz.de/en/career/in...
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Banito Lab (KiTZ, DKFZ) @banitolab.bsky.social · 26/11/2025
This will be a very exciting meeting! Looking forward to see you there Please spread the word
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Society for Developmental Biology @socdevbio.bsky.social · 12/11/2025
Olya Yarychkivska of @rockefeller.edu will kick off the #SDBPostdocSeminar with her talk "Myelin regulatory factor 1, identified by single cell transcriptomics, primes a migrating cell for non-apoptotic cell death" Image: Linker cell at the tail of a C. elegans male
Olya YarychkivskaLinker cell at the tail of a C. elegans male
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Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 27/10/2025
Emmy Noether grant for DKFZ researcher Jens Puschhof.👏 With this grant, he aims to decipher the role certain intestinal bacteria play in the earliest stages of colon cancer development and how this process can be halted. t1p.de/aoeve @jenspuschhof.bsky.social
t1p.de
Role of intestinal bacteria in the development of colorectal cancer: Emmy Noether grant for DKFZ researcher Jens Puschhof
The German Research Foundation (DFG) is funding a new Emmy Noether project led by Jens Puschhof from the German Cancer Research Center (DKFZ). With this project, the junior researcher aims to decipher...
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European Medicines Agency @ema.europa.eu · 23/09/2025
Paracetamol remains an important option to treat pain or fever in pregnant women. Following rigorous assessment of the available scientific data, we find no evidence that taking paracetamol during pregnancy causes autism in children. Read more 👉 www.ema.europa.eu/en/news/use-...
ema.europa.eu
Use of paracetamol during pregnancy unchanged in the EU | European Medicines Agency (EMA)
Paracetamol medicines can be used in pregnancy, in accordance with official recommendations
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Christin Schmidt lab @MUSC @cschmidtlab.bsky.social · 21/09/2025
I am more than thrilled to announce that I will be starting my own lab at the Neuroscience Department at MUSC in November 2025! We will be studying the origin of pediatric brain cancers through the lens of brain development! My lab is hiring see here: cschmidtlab.xn--com-gr63bea
cschmidtlab.com
Schmidt-lab | Pediatric Neurooncology MUSC
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Alex Eve @amjeve.uk · 20/08/2025
Like our sister journals, you can also submit an additional language abstract at @dev-journal.bsky.social and we cater for non-Western characters for author names. Did you know Development also facilitates retrospective author name changes?
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Baptiste Libé-Philippot @blibep.bsky.social · 18/08/2025
🧠 Position still opened! Don't hesitate to apply if you want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders!
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Sam Wang @samwang.bsky.social · 12/08/2025
The mid-decade redistricting wars are unending. I'll be on CNN with Jake Tapper to talk about what we know and what it means. Is democracy dead? Is there hope? What can citizens do? This Wednesday August 13, sometime around 5:00-7:00pm Eastern. Precise time when I know it.
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