Tonate virus (TONV) is a neglected mosquito-borne alphavirus of the Venezuelan equine encephalitis complex associated with febrile illness, encephalitis, and fetal central nervous system abnormalities...

The Heidelberg Medical Faculty of the University of Excellence Heidelberg is an outstanding location for innovative research, both nationally and i...

The Cluster of Excellence EXC 2124 “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen invites applications for Indepen...

The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

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A model for hit-and-run viral carcinogenesis in the bladder.

Mecp2 deficiency underlies Rett syndrome, a genetic disorder presenting with chronic low-grade inflammation of unknown origin. Here, the authors show that Mecp2 is a central regulator of the onset, br...

Author summary Hepatitis E virus (HEV) is an important yet often underestimated pathogen. Depending on the genotype, HEV infections can progress to chronicity, but the underlying mechanisms remain poo...

imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...

This year’s annual MSCA Postdoctoral Fellowships call has attracted considerable interest from the research community with 17,058 proposals submitted.

Author summary Host recognition of viral nucleic acids is fundamental for stimulating antiviral immunity. To prevent aberrant immune activation, cells must precisely differentiate “non-self” from “sel...

Salivary virome profiling revealed distinct virome profiles in Sjögren’s disease and a role for Vientovirus in triggering autoimmunity through molecular mimicry.

This study examines the function of G-quadruplex DNA secondary structures in mammalian promoters, revealing that they represent core promoter elements contributing to gene regulation by nucleosome exc...

imageimageInfluenza A virus infection increases host transposable element (TE) expression. This study provides evidence that some infection-induced TEs form double-stranded RNAs that accumulate in the...

Nature Communications - Costa-Verdera et. al describe a mechanism by which AAV vector genomes activate P53-mediated signalling in CNS cells involving downstream STING activation and...

In a context where some scientists in the United States may feel threatened or hindered in their research, our university is announcing the launch of the Safe Place For Science program, dedicated to w...