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Florian I. Schmidt lab

@fischmidtlab.bsky.social
164 followers 200 following 17 posts

Cell Biology meets Immunology and Virology, spiced up with nanobodies

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Reposted by Florian I. Schmidt lab
Jörg Spengler 🇪🇺 @joergspengler.bsky.social · 24/06/2026
Robert Habeck bringt es auf den Punkt! ✊ #Klimaschutz 🌍
Zitat: "WIR MÜSSEN UNS NICHT DAFÜR ENTSCHULDIGEN, KLIMASCHUTZ ZU MACHEN, SONDERN DIE IN DIE VERANTWORTUNG NEHMEN, DIE ES NICHT TUN.
ES GEHT NICHT UM DAS KLIMA, WENN WIR DAS KLIMA SCHÜTZEN, ES GEHT UM DIE FREIHEIT, SICHERHEIT UND DAS LEBEN
DER MENSCHEN."
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Reposted by Florian I. Schmidt lab
Margot Foley @mfoley25.bsky.social · 14/06/2026
#ObamaDay #ObamaAppreciationDay #BarackObama
A photograph of Barack Obama receiving the Nobel Peace Prize. The man standing with Barack Obama in the photo is Thorbjørn Jagland, who was the chairman of the Norwegian Nobel Committee at the time. Below the photo, large white text on a black background reads: "IT'D BE A REAL SHAME IF THIS PHOTO OF PRESIDENT OBAMA RECEIVING HIS NOBEL PEACE PRIZE WENT VIRAL TODAY, FOR  CB NO PARTICULAR REASON." A laughing emoji is centered at the bottom, and a circular logo with a silhouette of the Statue of Liberty and the words "THE RESISTANCE" is in the top right corner.
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Reposted by Florian I. Schmidt lab
Gregg Gonsalves @gregggonsalves.bsky.social · 06/06/2026
To the leadership of the American Diabetes Association: Dear Mr. Henderson and Dr. Kalyani, By now, you have probably received plenty of missives about the police action against scientists and clinicians with your own organization at your national meeting. 1/
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 23/05/2026
If you are interested in molecular regulation of innate immunity or nanobody technology, we have a few exciting postoc positions to fill in the Schmidt lab @unibonn.bsky.social in the context of @immunosens.bsky.social. Please share!
Postdoc positions in molecular immunology and nanobody technology in the Schmidt lab at Uni Bonn, Germany
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 23/05/2026
If you are interested in molecular aspects of innate immunity or nanobody technology, we have a few exciting postdoc positions to fill in the Schmidt lab @unibonn.bsky.social in the context of @immunosens.bsky.social. Please share!
Postdoc position in Molecular Immunology and Nanobody Technology in the Schmidt lab at Uni Bonn, Germany
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Reposted by Florian I. Schmidt lab
GfV - Gesellschaft für Virologie @gesvirologie.bsky.social · 18/03/2026
This yearˋs Löffler-Frosch-Medal for his lifetime achievements and contributions to virology goes to our former president Prof. Ralf Bartenschlager @ciid-heidelberg.bsky.social @uniheidelberg.bsky.social! So greatly deserved, congratulations, Ralf! #gfv2026
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 12/03/2026
Ready for the #BonnOrganoidSymposium 2026 at @unibonn.bsky.social ….
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Reposted by Florian I. Schmidt lab
Broz Lab @brozlab.bsky.social · 16/02/2026
We're thrilled to share the lab's latest publication demonstrating how caspase-4 and the non canonical inflammasome recognize cytosolic LPS by preferentially binding to the convex portions of membranes - both bacterial and micelles @cp-immunity.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation
The non-canonical inflammasome, comprising caspase-4 in humans, initiates pyroptosis upon sensing cytosolic lipopolysaccharide (LPS) from Gram-negativ…
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 29/01/2026
Early weekend read: Our new review on #antiviral #inflammasomes spearheaded by Jennifer Wuerth with some recommendations for inflammasome detection is out! @unibonn.bsky.social @immunosens.bsky.social www.mdpi.com/1999-4915/18...
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Reposted by Florian I. Schmidt lab
Ervin Fodor @efodor.bsky.social · 24/01/2026
Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 21/01/2026
Ever wondered how you can specifically inhibit #AIM2 #inflammasomes? @y-m-tesfamariam.bsky.social generated inhibitory AIM2 #nanobodies to ‬dissect inflammasome responses to #poxvirus infections in human #PrimaryCells @unibonn.bsky.social @immunosens.bsky.social link.springer.com/article/10.1...
link.springer.com
Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells - The EMBO Journal
The innate immune system is known for its ability to recognize cytosolic DNA as evidence of infection, but detailed studies of this process have been mostly limited to mice and cell lines. To investig...
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Reposted by Florian I. Schmidt lab
Pablo Pelegrin @ppelegrin.bsky.social · 07/09/2025
Looking for passionate candidate to apply to PhD fellowship to University of Murcia call: www.um.es/documents/d/... Interested students contact me!
um.es
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Reposted by Florian I. Schmidt lab
WachtenLab @wachtenlab.bsky.social · 21/08/2025
🚨 New in The EMBO Journal! Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins. 🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social 📄 www.embopress.org/doi/full/10....
embopress.org
BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal
imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 17/06/2025
Thrilled to start the 2nd Bonn #Organoid Day with more than 100 participants at @unibonn.bsky.social!
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Reposted by Florian I. Schmidt lab
Waggoner Lab @labwaggoner.bsky.social · 25/05/2025
KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency @cp-cellreports.bsky.social www.cell.com/cell-reports...
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Reposted by Florian I. Schmidt lab
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 24/05/2025
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...
youtu.be
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
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Reposted by Florian I. Schmidt lab
Cluster of Excellence ImmunoSensation @immunosens.bsky.social · 22/05/2025
Hurray! ImmunoSensation will go on! 🥳 The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded! Let us #celebrate 7 more years of #immunology in #Bonn 🎉 www.immunosensation.de/news/immunos...
immunosensation.de
Excellence Strategy Funds Bonn Cluster for Immune Research
The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…
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Reposted by Florian I. Schmidt lab
Jonathan Kagan @jkagan1.bsky.social · 18/05/2025
Want to live a longer and better life? Give creative people resources to make your life better. Harvard.edu
harvard.edu
Harvard University
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 06/04/2025
This work was spearheaded by @florianngohr.bsky.social at @unibonn.bsky.social. He is an outstanding immunologist/virologist currently looking for #postdoc opportunities!
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Florian I. Schmidt lab @fischmidtlab.bsky.social · 06/04/2025
Late #WeekendRead: We describe a novel reporter to visualize endogenous #inflammasome assembly. Suitable for cell lines, primary cells, and tissues as well as quantification by #microscopy and #flowcytometry. Happy to share. www.biorxiv.org/content/10.1...
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Reposted by Florian I. Schmidt lab
Bella Rauch @rauchlab.bsky.social · 13/03/2025
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science! Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
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